慢性頭痛의 病態生理

田珍淑 藥業新聞社 1984 (月刊) 醫藥情報 Vol.1984 No.2

A Case of Attention Deficit Hyperactivity Disorder in Association with Postinflammatory Hydrocephalus

전진숙 고신대학교(의대) 고신대학교 의과대학 학술지 1992 고신대학교 의과대학 학술지 Vol.8 No.2

-Abstract- An arrested hydrocephalus viewed as enlarged lateral and the third ventricles with thinning of corpus callosum was found on MR imaging in a ten year-old boy whose behavior was disruptive with hyperactivity, impulsivity and inattention, a typical clinical features of attention deficit hyperactivity disorder according to the DSM-Ⅲ-R, and was responsive to the stimulant. The hydrocephalus seemed to be secondary to tuberculous meningoenphalitis which had occurred at 12 months of his age, I reported the case to speculate organic causes of attention deficit hyperactivity disorder and reviewed articles related to the etiology of the attention deficit hyperactivity disorder.

장수와 치매의 예방

전진숙 대한신경정신의학회 2009 신경정신의학 Vol.48 No.5

Objectives: The aim of this study was to understand pharmacological and non-pharmacological methods of dementia prevention. Methods: An internet searchof literature published from 2006 thru 2008 was done using combinations of the words‘dementia’ and‘prevention’. These publications were subsequently reviewed. Results: 1) Reduction of risk factors:control of vascular risk factors (hypertension, diabetes mellitus, obesity, hypercholesterolemia, smoking, hyperhomocysteinemia, and platelet aggregation) and medical risk factors (head trauma, depression, herpes simplex, hyperthyroidism, and alcohol problems). 2) Pharmacological trial:NSAIDs, selective COX-2 inhibitors, estrogen replacement therapy, and antioxidants. 3) Healthy diet and nutrition:macronutrients (polyunsaturated fatty acid such as omega-3, alpha-linolenic acid, docosahexaenoic acid) and micronutrients (vitamins such as vitamin A, vitamin B1, 3, 6, 9, 12, vitamin C, vitamin D, vitamin E, vitamin K;minerals such as iron, iodine, magnesium, zinc, manganese, copper, cobalt, selenium;trace elements;and non-essential micronutrients such as polyphenols). 4) Regular excercise and activities:physical activities including aerobics, flexibility, and strength exerrcises;Recreational activities including participation in religious or social activities, healthy sex life with partner, and stimulating cognitive activities. Conclusion: The final goal of dementia treatment is primary prevention. However, there is no proven method to achieve this. Therefore, secondary prevention or preventative maintenance through risk reduction and introduction of a healthy lifestyle in an attempt to postpone the onset of disease is a realistic goal. 치매치료의 궁극적 목표는 일차적 예방(primary prevention)이다. 그러나, 아직 이를 위한 치료법은 개발되지 않았다. 치매의 진행을 예방할 수 있는 약물치료나 생활양식은 입증된 것이 없다. 따라서, 현재로서는 이차예방이나 예방적 유지책(환자의 전반적 건강, 정신상태, 기능을 극대화 시킴으로써 과다한 질병을 감소시키는)에 중점을 두는 수밖에 없다. 다시말하면, 위험인자를 감소시키거나, 건강한 생활양식을 도입하여 치매의 발병을 지연시키는 것이다.

신경성 식욕부진증과 우울증에서 시상하부-뇌하수체 기능의 비교 : 증례 및 문헌고찰

전진숙,장환일,한홍무 서울대학교 의과대학 정신과학교실 1985 서울醫大 精神醫學 Vol.10 No.2

정신과 입원환자에서 발생한 중수염에 대한 고찰

전진숙,이근후 대한신경정신의학회 1981 신경정신의학 Vol.20 No.4

The 10 cases of appendicitis experienced among psychiatric in patients in EwhaUniv. Hospital from Jan . 1977 to Mar. 1981 were retrospectively reviewed. The authers tried to find out characteristics of the clinical features and laboratory data, and the nclarify probable causes of reduced peristalsis which was presumed as the primary process for minglum in al obstruction in view of anticho linergic effect of psychotropic drugs and psychogenic factors, and finally to suggest existing problems in diagnosing and managing psychiatric patients with surgical illness. The following results were obtained; 1. Schizophrenic disorder was the most frequent psychiatric diagnosis. Most of patients showed active psychotic symptoms. Dynamic formulations were mainly composed of guilty or shame (50.0%), hostility and anxiety. 2. It occurred most frequently in the twenties (40 .0% ), and in winter (50.0%). 3. The clinical symptom began with constipation (70.0%) prior to the onset of pain on the R .L .Q . (70.0%) which was the most frequent subjective symptom of appendicitis. Most of patients showed direct tenderness, decreased bowel sound (60.0%) and abdominal distention (40.096) as physical signs. 4. The simple abdomen showed gaseous distention and other ileus sign in 7 cases (87.5%). The hematologic findin g showed normal number of leukocyte in 44.4% and leukocytosis in 33.3%. 5. Most of cases were operated with in 5 days’ lapse after the onset of appendicitis. 6. The operative and histopathological findings showed 9 cases of appendiceal lumen filled with fecalith (90.0% ). 5 cases (50.0%) were acute focal appendicitis, 2 cases normal appendix, another 2 cases acute suppurative appendicitis, and 1 case was chronic appendicitis. 7. Most of patients were hospitalized for 8 days (60.0% ). 8. During stay in the G-S ward, the postoperative psychiatric course showed 1 case of aggrav ation and 9 cases (90.0%) of improvement or no change. But, after discharge, it showed 7 cases of improvement (70.0%) and 3 cases of aggravation (30.096). 9. 4 cases (40.0%) were medicated with one kind of neuroleptic drug combined with anticho linergic drug, 1 case (10.0%) with over two kinds o f neuroleptics combined with anticho linergic d ru g & tricyclic antidepressant, and 5 cases (50.0%) with over two kinds of neuroleptics & anticholinergic drug.

보건수요에 따른 보건소 사업의 정책시차 분석

전진숙 한국공공관리학회 2015 한국공공관리학회 학술대회 Vol.2015 No.8

보건소는 최일선 보건행정조직으로서 주민들의 건강에 필수적인 다양한 보건의료서비스를 제공하고 있으며, 국민의 건강증진에 기여하며 사회 취약계층의 의료안전망 역할을 담당하고 있다. 보건사업들의 보건의료수요를 적기에 인지하여 정책을 수립하고, 시행하는 과정에서 시간의 개념은 대단히 중요하다. 이러한 관계에서 정정길(2002a)은 시차적 접근 이론(time-lag approach theory)을 제시하였으며 시차적 접근은 시차를 원인변수로 보고 사회과학적 인과관계와 정책시행의 적시성(timing 또는 timeliness)을 중요시 하였다(정정길, 2002b). 본 논문은 보건의료수요를 어느 시점에서 인지하고 정책을 시행하는 것이 가장 적시성이 있는지에 초점을 두고 사업들을 분석하였으며, 본 논문에서 인지시차(recognition lag)는 보건의료수요의 지표가 최고점에 이른 시점부터 국가 대응정책이 나온 시점까지이며, 집행시차(action lag)는 보건사업을 추진할 법, 제도, 예산 등의 인프라를 갖추어 사업을 본격적으로 시행한 시점까지를 말한다. 보건소가 비중 있게 추진한 역점사업인 가족계획사업, 심뇌혈관질환 예방관리사업, 치매관리사업을 선택하여 시차적 접근 이론을 근거로 인지시차와 집행시차를 분석하였으며, 이는 국민의 건강증진과 삶의 질 향상 그리고 사회경제적 정책비용을 절감할 수 있는 방안을 제시하고자 하였다. 보건의료수요를 적기에 인지하여 대응정책을 수립하고 집행하기까지의 정책시차를 줄여야 하며, 정책집행자들은 시행하고자 하는 보건사업에 대한 지식과 이해, 시차의 중요성과 사업의 전개과정에 대한 통찰력이 있어야 한다. 보건의료수요는 지속적으로 변화하므로 시차적 관점에서 적기에 인지하여야 하며, 사업에 필요한 조직을 정비하고 예산과 인력 등을 조기에 투입하여 사업시행의 지연에 따른 정책비용을 최소화시켜야 한다 초기대응의 부실로 인해 golden time을 놓쳐 국가적 혼란을 가져온 중동호흡기증후군(MERS)의 사태에서 보듯이 정부는 보건의료수요가 발생했을 때 보다 적극적인 대처로 국민들이 안전하고 건강한 삶을 누릴 수 있도록 하여야 한다. 또한 고령사회와 초고령사회를 대비하기 위해 보건소의 기능과 역할을 재정립하고, 모든 보건사업의 정책시차를 줄여나가려는 확고한 대응전략이 필요한 시점이다.

신경생리학적(神經生理學的) 동물실험(動物實驗)의 기초(基礎)

전진숙,Cheon, Jin-Sook 대한수면의학회 1994 수면·정신생리 Vol.1 No.2

The neurophysiological study has been widely used in the search of the relation between brain and behavior. The basic techniques for the animal experiments of this kind such as stereotaxic techniques, lesioning methods, the methods of electrical stimulation and confirmation of histological location were simply reviewed. Nevertheless, the importance of complementary neurochemical, neuroanatomical and behavioral studies can not be neglected.

신경정신장애의 분자 유전학적 접근

전진숙 고신대학교(의대) 고신대학교 의과대학 학술지 1993 고신대학교 의과대학 학술지 Vol.9 No.1

-Abstract- The molecular genetic techniques including recombinant DNA technology play an important role in modern neuropsychiatric research and practice. The basic concepts of molecular genetics and the clinical applications were reviewed in degenerative disorders including Alzheimer's disease, schizophrenia, mood disorders, and other neurological disorders. The molecular genetic methods seem to have potential value in the following applications; 1. The complete mapping of human genomes 2. The localization and cloning of genes for the hereditary disorders 3. The diagnosis and predictability of risks for the single-gene controlled disorders 4. The identification of gene products, and biochemical and physiological basis for the genetic diseases 5. The development of preventive methods and therapeutic drugs 6. In the future, availability of gene-replacement therapy for the same disorders

Fluoxetine 및 Sertraline으로 유도된 심한 세로토닌 증후군 1예

전진숙,이상신,김성희,조웅,Cheon, Jin-Sook,Lee, Sang-Shin,Kim, Sung-Hi,Cho, Woong 대한생물정신의학회 2001 생물정신의학 Vol.8 No.1

A 54-year old male patient who was suffering from bipolar I disorder for 19 years and was admitted to the National Bugok Mental Hospital due to a depressive episode, was referred to the Kosin University Gospel Hospital. On arrival at the emergency room, he had confused mentality with disorientation, memory impairment, hypomania, marked anxiety and hyperirritability. The change of neuromuscular activity such as ataxia, gait disturbance, tremor, shivering, myoclonus and epileptic seizures was also shown. In addition, the symptoms and signs of autonomic instability including diaphoresis, tachycardia, hypotension, fever and facial flushing were noticed. The above symptoms developed after the administration of sertraline successive to the discontinuation of fluoxetine without any washout period. The degree of severity seemed to be severe because he had epileptic seizures, fever and hypotension. He was recovered from the severe serotonin syndrome by the supportive symptomatic treatment with sodium valproate, clonazepam, lorazepam and cyproheptadine after cessation of the selective serotonin reuptake inhibitors during hospitalization. Therefore, this rare case of severe serotonin syndrome was reported and related literatures were also reviewed.

자율주행차 AI의 도로교통법 준수 운전능력평가 시나리오 개발 연구

전진숙,정현숙 대한교통학회 2022 대한교통학회 학술대회지 Vol.87 No.-