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      • KCI등재
      • SCOPUSKCI등재

        주초와 주중 혈액 투석 전 혈색소를 기준으로 조혈호르몬 용량 조절 시 평균 혈색소의 변화

        장은희 ( Eun Hee Jang ),강우헌 ( Woo Hun Kang ),최소연 ( So Yeon Choi ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.3

        목적: 혈액 투석 환자의 가장 적절한 목표 혈색소 농도는 11-12 g/dL이다. 조혈호르몬 (EPO) 치료 기준으로서 주초 혈액 투석 전 혈색소 (day1 preHD Hb)는 과도한 체중 증가로 인해 평균 혈색소를 저평가하여 과치료를 유발하고 둘째 혈액 투석 전 혈색소 (day3 preHD Hb)는 평균 혈색소를 잘 반영한다고 한다. 저자들은 국내보험 기준하의 일정한 EPO 프로토콜을 적용하여 다른 날짜의 투석 전 혈색소를 기준으로 EPO용량을 조절하였을 때 평균 혈색소의 변화를 관찰하고자 하였다. 방법: 제주대학교 병원에서 3개월 이상 투석과 EPO 치료를 받고 있는 환자 총20명을 대상으로 무작위로 두 군으로 나누어 A군 (n=11)은 day1 preHD Hb을 기준으로 B군 (n=9)은 day3 preHD Hb을 기준으로 정해진 지침에 따라 EPO를 8주간 투여한 후 이후 8주간은 cross over하였다. 연구 기간 동안 Transferrin saturation >20%, ferritin >100 pg/mL로 유지하였으며 mean Hb은 Day1 predialysis Hb+ (Day3 postdialytic Hb-Day3 predialytic Hb)/3으로 계산하여 2주 간격으로 측정하였고, 4주 간격으로 철분상태를 평가 보충하였다. EPO의 부작용으로 투석 전 평균 혈압을 비교하였고 항고혈압약제의 증량 또는 추가 빈도를 관찰하였다. 결과: 각 군에서 평균 연령과 성별, 평균 투석기간은 유의한 차이가 없었다. 각각 기저치, 8주, 16주째 EPO 프로토콜 적용 후 평균 혈색소는 A군에서 10.05±0.60, 10.10±1.2, 10.11±1.03 g/dL, B군에서 9.93±0.62, 9.72±0.99, 10.30±1.13 g/dL으로 유의한 차이가 없었다. 기저치, 0-8주간, 8-16주간 EPO 요구량은 A군에서 107.2±74.7, 110.9±37.0, 71.8±41.9 IU/kg/week, B군에서 95.4±94.6, 76.58±45.4, 85.6±35.7 IU/kg/week으로 유의한 차이는 없었다. 투석 전 평균 혈압은 시험 전, 8주, 16주째 두군 모두 차이가 없었으나 (107±12 vs 107.0±9, 108±8 vs 101±15, 101±6 vs 96±9 mmHg), 항고혈압제 증량이 각각 day1 preHD 기준시 3명에서 필요했다. 결론: 본 연구에서 주초, 주중 투석 전 혈색소 수치를 기준으로 EPO용량을 조절했을 때 EPO투여량 및 평균 혈색소에는 차이가 없었다. Purpose: The time average hemoglobin concentration (Hb-Tac) is more likely to represent hemodialysis (HD) patients` true hemoglobin due to variable hemoglobin concentration. This study was performed to evaluate the effect of erythropoietin adjustment on the Hb-Tac according to the Hb of different hemodialysis days. Methods: A controlled, randomized, cross-over study, where 20 stable hemodialysis patients (7 males, 13 females, mean age 57.8±3.0 year, mean HD duration 973±707 days) acted as their own controls. EPO adjustment was performed by protocol and according to preHD Hb of the first HD session (group A) or the second HD session (group B) in cross over for each 8 weeks. Serial Hb-tac were calculated by equation [mid week preHD Hb+[midweek pre HT [midweek preHD Hb+(midweek postHD Hb-preHD Hb)/3] every two weeks during the entire study periods. Their iron status were monitored and maintained adequately as K/DOQI guidelines. Results: There was no significant difference in clinical parameters except age during the entire study period. Mean hemoglobin at randomization and after 8, 16 weeks were 10.0±0.60, 10.10±1.19, 10.1±1.03, respectively, in group A compared with 9.93±0.62, 9.72±1.00, 10.3±1.12 g/dL in group B. Mean weekly epoetin alfa dosage at randomization and after 8, 16 weeks were 107.2±74.7, 123.2±43.1, 123.0±85.0 IU/kg/week, respectively in group A compared with 95.4±94.7, 107.4±60.7, 125.5±85.0 IU/kg/week in group B. There were no significant differences in Hb-tac and EPO dosage. Addition of antihypertensive occurred in three patients during EPO adjustment to preHD Hb of the first session. Conclusion: EPO dose adjustment according to the different day preHD Hb does not affect the Hb-tac and total EPO.

      • KCI우수등재
      • SCOPUSKCI등재

        Mycophenolate mofetil 치료 중인 전신성 홍반성 루푸스 환자에서 동시에 발생한 주자폐포충 폐렴 및 거대세포 바이러스 폐렴

        장은희 ( Eun Hee Jang ),김민옥 ( Min Ok Kim ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.4

        A 36-year-old woman developed concurrent Pneumocystis carinii pneumonia (PCP) and cytomegalovirus (CMV) pneumonia. She was diagnosed as lupus nephritis two years ago and was on immunosuppressive therapy with prednisolone and mycophenolate mofetil. She developed dyspnea with moderate hypoxemia. Chest X-ray and HRCT showed diffuse interstitial infiltration and ground glass opacity. The diagnosis of concurrent PCP and CMV was performed by the virus culture and PCP PCR of bronchoalveolar lavage fluid. She recovered following treatment with trimethoprim-sulfamethoxazole, prednisolone, gancyclovir for three weeks.

      • KCI우수등재
      • KCI등재
      • KCI등재
      • KCI등재

        전국 병원영양사의 직무만족도 현황 및 관련요인

        장은희 ( Eun Hee Jang ),류은순 ( Eun Soon Lyu ),이송미 ( Song Mi Lee ),박유경 ( Yoo Kyung Park ),이은 ( Eun Lee ),차진아 ( Jin A Cha ),박미선 ( Mi Sun Park ),이호선 ( Ho Sun Lee ),라미용 ( Mi Young Rha ),이승민 ( Seung Min Lee ) 대한영양사협회 2014 대한영양사협회 학술지 Vol.20 No.4

        The objective of this study was to examine job satisfaction status and its related factors among dietitians working in hospitals. A survey questionnaire was sent to dietitians working in tertiary, general, and convalescent hospitals in Korea. The study sample hospitals included all tertiary hospitals (n=43), and the sample of general hospitals (n=114) and convalescent hospitals (n=240) was randomly selected using a stratified sampling method. A total of 665 dietitians completed the survey questionnaire. The questionnaire included27 job satisfaction questions on task, stability·vision, working conditions, and relationship areas, and the questions on task improvement need. The job satisfaction scores in all four areas ranged from2.53/5.00 to 3.89/5.00, implying generally low job satisfaction level in hospital dietitians. The job satisfaction levels in the convalescent hospital group were significantly lower compared to those in the tertiary and general hospital groups. Whereas job satisfaction levels of tertiary and convalescent hospital groups did not differ by number of beds, those of the general hospital group increased significantly with the number of beds for all four areas. Multivariate regression analysis results showed that hospital type was a significant predictor of job satisfaction level for all four areas. Job satisfaction of relationship area was also significantly affected by the number of beds, whereas that of working conditions was influenced by annual income and working experience. The study findings provide useful information in planning clinical dietitians` optimal supply outlook for the improvement of clinical nutrition services.

      • KCI등재

        암 환자의 우울에 적용한 중재 효과의 메타 분석

        장은희(Jang, Eun Hee),최경숙(Choi, Kyung Sook),권수진(Kwon, Soo Jin) 대한종양간호학회 2013 Asian Oncology Nursing Vol.13 No.1

        Purpose: The purpose of this study was to analyze the characteristics and effect size of the intervention study applied to the depression of the cancer patient. Methods: A total of 749 studies published from 1990 to 2011 were searched through the search databases and among them, 35 examples satisfied the inclusion criteria. Three independent researchers implemented the methodological qualitative evaluation. The data were analyzed using meta-analysis. Results: For the depression of the cancer patient, 19 various interventions were applied. The size of the intervention effect that can be analyzed in terms of effect size came out as OR of the laugh therapy 8.122 (p=.073), OR of the music therapy 4.418 (p=.014), OR of the integrated therapy 4.418 (p=.015). Conclusion: This study suggests that the music therapy and integrated therapy is effective to the depression of cancer patients. Furthermore, in order to check the effects of intervention, we should need to include more randomized controlled studies and various intervention studies.

      • KCI등재

        BPO 거래의 당사자간 법률관계 연구

        장은희(Eun-Hee Jang),이주섭(Ju-Seob Lee),유준수(Joon-Soo Yoo) 한국국제상학회 2021 國際商學 Vol.36 No.3

        Purpose : The main purpose of this study was to consider the legal relationship between the parties involved in the BPO system. Therefore, the study was conducted to the effect that the users of this system would understand and comply with the rights and obligations of parties to regulate in the Uniform Rules for Bank Payment Obligations. Research design, data, methodology : This study mainly explored the basis of domestic papers, academic textbooks and that studied the electronic trade payment systems. Results : The legal relationship of parties involved in the BPO system is largely divided into relationship between the seller and the buyer, the buyer’s bank and the seller’s bank, the seller and the seller’s bank, and the buyer and the buyer’s bank. Conclusions : The four parties involved in the BPO system need to understand and comply with their rights and obligations under the Uniform Rules for Bank Payment Obligations. 현대의 외환 및 결제시스템이 인터넷을 포함한 전자매체를 상거래에 등장시켰고, 수출입업자가 국제거래에서 겪게 되는 리스크를 완화시키고자 등장한 것이 BPO 결제방식이다. 국제상업회의소와 SWIFT는 BPO 방식의 이용에 따른 가이드라인을 제시하고자 2013년에 BPO 통일규칙을 제정하였고, 현재 공식적으로 시행 중에 있다. 본고에서는 BPO 통일규칙 조문의 적용범위 및 대상, 주요 조문내용 등을 개괄적으로 검토한 후 BPO 거래에 참여하는 당사자간 법률관계를 매도인과 매수인간의 관계, 매수인과 매수인은행간의 관계, 매도인과 매도인은행간의 관계, 매수인은행과 매도인은행간의 관계로 각각 구분하여 상세히 검토하였다. 기본적으로 본 연구는 문헌연구방법을 취하였는데, BPO에 관련된 국내외 논문 및 통일규칙을 주로 참조하였고, 연구의 핵심부분인 당사자간 권리의무를 밝히는데 있어서는 국내외 결제 및 실무서적을 다수 이용하였다. 국내에서 BPO 거래의 원활화에 기여하고자 본 연구는 관련 당사자들의 법률관계를 명확히 밝히려 하였고, 이를 통해 실무상 이용편의 및 혼란을 제거하는데 그 목적을 두고 있다.

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