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      • 소아 급성 위장관염에서의 원인과 임상양상

        임익재 ( Ik Jae Im ),이미정 ( Mee Jeong Lee ),정은희 ( Eun Hee Chung ),유지숙 ( Jeesuk Yu ),장영표 ( Young Pyo Chang ),박우성 ( Woo Sung Park ),박귀성 ( Kwisung Park ),송낙수 ( Nak Soo Song ),백경아 ( Kyung Ah Baek ),차윤태 ( Yune 대한소아감염학회 2006 Pediatric Infection and Vaccine Vol.13 No.2

        목 적 : 소아에서 흔한 감염성 질환인 급성 위장관염은 바이러스, 원충, 세균 등 다양한 원인에 의해 발생한다. 소아 위장관염의 다양한 원인에 대한 연구가 드물어 이에 급성 위장관염으로 방문했던 환아들을 대상으로 병원체의 원인과 임상양상에 대해 연구하고자 하였다. 방 법 : 2004년 12월부터 2005년 12월까지 설사, 구토 등의 위장관염 증상으로 단국대학교병원 외래를 내원하였거나 입원한 환아들을 대상으로 하였다. 대변검사는 총 17종의 원인 병원체에 대한 검사를 하였다. RT-PCR에 의한 norovirus, ELISA에 의한 rotavirus, astrovirus, adenovirus와 선택적 배지를 사용하여 Salmonella spp., Shigella spp., C. perfrigens, Campylobacter spp., E. coli, Vibrio spp., S. aureus, B. cereus, Yersinia spp., L. monocytogenes에 대한 배양검사, EIA에 의한 C. parvum, E. histolytica, G. lamblia에 대한 검사를 하였다. 원인별 임상양상에 대해 후향적으로 의무기록지를 검토하였다. 결 과 : 총 215례 환아에서 대변검사를 시행하였으며 이중 89례(41.4%)가 양성을 보였다. 89례의 남녀비는 1.3:1, 평균나이는 25개월(3일~14세), 평균 입원기간은 3.4일(1~10일)이었다. 연령별로 1개월 미만이 4례(4.5%), 1~2개월이 4례(4.5%), 3~12개월 24례(26.7%)였고 13~48개월이 47례(52.8%)로 가장 많았으며 4세 이상이 10례(11.2%)의 분포를 보였다. 원인별로 바이러스가 68례(77.5%), 세균이 26례(28.9%), 원충이 21례(23.6%)에서 검출되었고 바이러스류에서는 rotavirus(50례), 세균류에서는 salmonella(10례), 원충류에서는 C. parvum(11례)이 가장 많이 검출되었다. 양성 환아의 22례(24.4%)에서 2종 이상의 혼합감염을 보였고 바이러스와 원충의 혼합감염이 가장 많았다. 결 론 : 본 연구에서 소아 급성 위장관염을 일으키는 것으로 알려진 다양한 병원체들이 검출되었다. 이는 소아 급성 위장관염의 치료에 많은 정보를 줄 것으로 생각되며 향후 소아 급성 위장관염의 다양한 원인에 대한 광범위하고 지속적인 연구가 필요할 것으로 사료된다. Purpose : The purpose of this study is to evaluate epidemiological data of pathogens obtained from stool exams and compare them with the clinical course in pediatric patients with symptoms of acute gastroenteritis. Methods : Subjects were selected from patients presenting with symptoms of acute gastroenteritis who visited the outpatient clinic or who were admitted to the Dankook University Hospital from December of 2004 to December of 2005. Stool exams for 17 pathogens was performed. RT-PCR was used to detect norovirus and enzyme-linked immunoabsorbant assay (ELISA) was used to detect rotavirus, adenovirus and astrovirus in the subjects stool samples. Ten different species of bacteria(Salmonella spp., Shigella spp., Clostridium perfrigens, Campylobacter spp., Escherichia coli, Vibrio spp., Staphylococcus aureus, Bacillus cereus, Yersinia spp., and L. monocytogenes) were each selectively cultivated and enzyme immunoassays(EIA) was used to test for antigens for C. parvum, E. histolytica and G. lamblia. Retrospective chart review was performed for comparisons of clinical manifestations. Results : A total of 215 subjects was selected and of these 89 cases(41.4%) showed positive results for at least one pathogen. Male to female ratio was 1.3:1. Age distribution showed 4 cases less than one month(4.5%), 4 cases from 1~2 months(4.5%), 24 cases from 3~12 months(26.7%), 47 cases form 13~48 months(52.8%), 10 cases greater than 48 months (21.2%). Viruses showed the greatest proportion of cases with 68 subjects(77.5%), of these rotavirus being the most commonly reported in 50 cases. Bacteria was identified in 26 cases (29.2%), of these nontyphoidal salmonella was noted in 10 cases. Protozoa followed with 21 cases(23.6%), of these C. parvum was noted in 11 cases and G. lamblia was noted in 10 cases. Mixed infections with more than two pathogens were seen in 22 cases(24.7%), of these viral infection with accompanying parasitic infection was seen in 12(54.5%) cases. Conclusion : In this study we examined various pathogens known to cause acute gastroenteritis in children. Further studies for various pathogens can provide useful information for management of the acute gastroenteritis.

      • KCI등재

        천막상 병변 뇌졸중 환자의 삼킴 시간과 흡인에 대한 음식물의 점도 및 양의 효과

        임익재(Ik Jae Im) 한국언어치료학회 2017 言語治療硏究 Vol.26 No.3

        Purpose: Diet modification has become one of the most common interventions and strategies for dysphagia, which isconsidered important for improving efficient and safe swallowing. However, to date, the effects of modification, involving liquid thickening and volume decreasing, are not fully understood. The purpose of this study was to investigate the effect of bolus viscosity and volume on temporal measurements and aspiration of oropharyngeal swallowing in supratentorial stroke patients. Methods: Seventy-eight stroke patients (mean age=64) with supratentorial lesions participated and underwent both videofluroroscopic swallowing examinations (VFSEs) and a brain magnetic resonance imaging study. VFSE data recorded during swallowing tasks of 2cc thin liquid, 5cc thin liquid, and 5cc curd yogurt and VFSE data also compared with those obtained from difference of bolus viscosity and volume. Temporal measurements of oropharyngeal swallowing from VFSEs data were used to measure the aspect of swallowing efficiency such as oral transit duration, pharyngeal transit duration, initiation of laryngeal closure and laryngeal closure duration. A penetration-aspiration scale was used to assess the aspect of swallowing safety. Results: Oral transit duration for 5cc curd yogurt swallowing was shown to be longer than thin liquid swallowing. Pharyngeal transit duration for 5cc thin liquid swallowing was shown to be shorter than 2cc thin liquid swallowing. Scores on the penetration-aspiration scale were significantly different according to both viscosity and volume of blouses. Conclusions: Our findings demonstrate the potential of liquid thickening agents to enhance swallowing efficiency and safety in supratentorial stroke patients.

      • KCI등재

        정상 성인에서의 전기성문파형 검사 ; 연하장애 환자의 전기성문파형 검사를 위한 예비연구

        김영빈,이주경,임대호,백진아,고승오,임익재,김현기,신효근,Kim, Young-Bin,Lee, Ju-Kyung,Leem, Dae-Ho,Baek, Jin-A,Ko, Seung-O,Im, Ik-Jae,Kim, Hyun-Ki,Shin, Hyo-Keun 대한악안면성형재건외과학회 2008 Maxillofacial Plastic Reconstructive Surgery Vol.30 No.5

        Electroglottography (EGG) is a simple and non-invasive technique for analyzing the vibratory patterns of the vocal folds by detecting impedance changes across the larynx. An abnormal electroglottogram is shown in patients who have a dysphagia associated with neuromuscular disorder. Electroglottography offers reliable informations for diagnosis of swallowing disorder and gives quantitative datas. The purpose of this study is to provide the normal value of electroglottography in normal adults. We took electroglottograms of 80 adults who have no problem in swallowing and utterance. EGG data were analyzed to find out the value of Pitch, Jitter and Closed quotient with a commercially available software. There were significant differences between a usual voice and loud voice in 3 measures on the EGG signalmean pitch, Avg. jitter, mean quotient. To get a proper electroglottography, phonation of a usual voice was better than a loud voice. Four measurements- S.D pitch, Avg. Jitter, Mean closed quotient, S.D closed quotient- were independent of sex for adult. Three measurements- Mean pitch, S.D pitch, Mean closed quotient - were independent of age for adult aged twenties to fifties. The Avg. Jitter of twenties appeared to be lower than those of forties and fifties. The S.D closed quotient of twenties appeared to be lower than those of thirties, forties and fifties.

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