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RISS 인기검색어
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- 저자 : 임경욱(Kyong Wook Yim) (검색결과 4 건)
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임경욱(Kyong Wook Yim),고광철(Kwang Chul Koh),김유철(Yoo Chul Kim),임용철(Yong Chul Lim),이효석(Hyo Suk Lee),윤용범(Yong Bum Yoon),송인성(In Sung Song),김정룡(Chung Yong Kim) 대한내과학회 1988 대한내과학회지 Vol.35 No.1
N/A There is plenty of evidence that the intestinal disaccharidases such as sucrase and maltase are adaptive by their substrates. However the intestinal lactase adaptiveness is still controversial despite results which positively suggest its adaptiveness in young experimental animals. The authors designed the following experiment with six groups of adult Wistar rats, each of which consists of ten 210 g average adult rats, to investigate whether dietary lactose solutions would increase the intestinal lactase specific acitivity and to observe the effects of various dietary solutions on other intestinal enzyme specific activities at the same time. All of the animals were fed by standard rat chow ad libitum and the first group (control) was made to suck tap water the second group a 5% glucose solution, the third group a 10 sucrose solution, and the fourth, fifth, and sixth groups 5%-, 10%- and 15% lactose solutions respectively, also ad libitum as the fluid source for a six week period. At the end of the experiment, the small intestines were divided into three segments of equal length from the Treitz ligament to the terminal ileum, from each of which one tissue section was made and specific enzyme activities (lactase, sucrase, trehalase, alkaline phosphatase and aminopeptidase N) were assayed. The results were as follows: 1) There was no difference in mean body weight during the experimental period. (mean±S.D; 230±12.3) 2) No histological differences between the groups were noted in each of the three segments. 3) The intestinal trehalase, alkaline phosphatase, aminopeotidase N, and lactase, which was the key enzyme of this experiment, were not adapted by these experimental solutions. 4) The intestinal sucrase specitic activities, especially of the middle segment, from animals fed with 5% glucose, 10% sucrose, 10%-and 15%-lactose solutions, in- creased from a control group value of 41.8±18.4 to 72.1±15.1, 73.0±12.0, 71.3±24.9 and 66.4±11.0mu/mg protein (p<0.01 in all) respectively, confirming again its adaptiveness. We concluded that the intestinal lactase was not adapted by these 5-15% lactose solutions in six weeks, To the contrary, the sucrase was adapted by various carbohydrate solutions which suggested that the adaptation was substrate non-specific and was by local effect rather than distant hormonal or neural effects.
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송인성,최규완,김정룡,임판식,임경욱,윤한두 대한소화기내시경학회 1987 Clinical Endoscopy Vol.7 No.1
The purpose of this study is to review the clinical and pathological features of pseudomembranous colitis in Korea. Ten cases of psedomembranous colitis, which were diagnosed by sigmoidoscopy and biopsy at the Seoul National University Hospital from May 1982 to occtober 1985, were analyzed in terms of the age and sex distribution, underlying diseases, presumptive causative antimicrobials, symptomatology, involved site and tratment. 1) The disease was more prevalent above sixth decade with a slight preponderance on the female. 2) The underlying diseases of the patients were the uterine cervix cancer in 3 cases and one case each of the nasal polyp, cataract, degenerative arthritis, tuberculous gradmuloma, SLE with menngitis, CVA and gingival abscess. 3) As for the presumptive causative drugs, cephalosporin were assaciated in 6 cases, aminoglycoside m 7 cases, penlcillin in 3 cases, Bactrim in 3 cases, antituberculosis drugs in 1 case and anticancer drugs in 1 case. 4) As for the anatotmical distribution of the lesion, the rectum was involved in 5 cases, the rectum and sigmoid colon in 4 cases and up to the descending colon in 1 case. 5) All the cases were cured by medical treatment. In 5 cases, discontinuation of the antimicrobial drugs and supportive care only were effective and in other 5 cases, vancamycin and/or metronidazole together vrith cholestyramine were added to the regimen.
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십이지장궤양에 대한 Nizatidine 과 Cimetidine 의 치료효과에 대한 비교 연구
송인성,최규완,윤병철,김정룡,이풍렬,정숙향,임경욱 대한소화기학회 1992 대한소화기학회지 Vol.24 No.2
Therapeutic effect of Nizatidine, a new H₂-receptor antagonist for the treatment of duodenal ulcer disease, was compared with that of cimetidine in an 8 week, randomized, double-blind trial. Patients were randomly aIlocated to receive either nizatidine 300 ㎎ h.s, or cimetidine 300 mg q.i.d. Patients were treated for 4 or 8 weeks. Follow-up endoscopy was performed at week 4 and 8. No more medication and follow up endoscopy was done in patients healed in week 4 follow up endoscopy. Healing rate with cimetidine 300 ㎎ q.i.d were numerically, (but not statistically significantly) superior to those with nizatidine 300 ㎎ h. s. at each treatment period. Ulcer healing rate at wk 4 and 8 were 45.4% (10/22) 71 4% (15/21) for nizatidine and 57.9% (11/19), 84.2% (16/l9) for cimetidine respectively. The therapeutic effect of nizatidine for duodeual ulcer was thought to be comparable to that of cimetidine.
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정현채,송인성,김재준,최규완,윤병철,김정룡,이풍렬,임경욱,정숙향 대한소화기내시경학회 1993 Clinical Endoscopy Vol.13 No.1
The gastric polyps may be premalignant lesions and they should be removed as possible. The gastric polyps can be remoued by various endoscopic methods. The safety and therapeutic effectiveness of snare polypectomy, neodymium YAG laser therapy and electrocutery were compared in a total number of 106 patients who were diagnosed as benign polyps by means of endoscopic biopsy.Safety was evaluated by the rate of complications such as perforation and bleeding, and therapeutic effectiveness was evaluated by the average numbers of treatment session of each modality. Average numbers of treatment session of snare polypectomy, laser therapy and electrocautery were 1.04, 1.38 and l.44, respectively. Average numbers of treatment session of snare polypectomy were significantly (p$lt;0.05) lower than those of other two methods. Perforation was not occurred in any group. Bleeding rates after snare polypectomy, laser therapy and electrocautery were 17.4%, 1.0% and 3.8%, respectively. Bleeding was significantly (p$lt;0,05) more frequent after snare polypectomy than after other two methods. In conclusion therapeutic effectiveness was best in snare polypectomy but complication was most frequent after snare polypectomy. There was no difference between laser therapy and electrocautery for therapeutic effectiveness and safety. Therfore, laser therapy and electrocautery caa be used for the removal of flat adenoma, alternatively.
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