대중교통 통행배정모형 개발 및 통행량 기반 대중교통 기종점통행량 추정

이신혜(Shin Hae Lee) 대한교통학회 2002 대한교통학회 학술대회지 Vol.41 No.-

교통혼잡 문제가 점점 심각해짐에 따라 대중교통의 중요성은 날로 부각되며, 대중교통을 지원하기 위한 정책들이 속속 입안되고 있어 대중교통을 심도 있게 분석할 수 있는 틀의 개발은 필연적이라 할 수 있다. 이에 본 연구는 대중교통 통행배정모형 개발과 대중교통 기종점통행량(OD) 추정을 목적으로 수행되었다. 대중교통 통행배정모형의 개발부분에서는 기존의 대중교통 통행배정모형이 개별차량과 다른 대중교통의 특성을 정확히 반영하고 있지 못하다는 한계를 극복하고자, 최적경로 탐색에는 유전자 알고리즘(Genetic Algorithm)을 통행량 배정에는 로짓모형을 기반으로 한 확률적 통행량 배정모형(Stochastic Network Loading ModeI)을 이용하여 TATSN 모형을 개발하였다. 그리고, 대중교통 기종점통행량의 추정은 전통적인 기종점통행량 추정 방법인 기종점조사 방법이 시간과 비용이 과대하게 소요된다는 단점을 인식하여 관측통행량을 이용하여 추정하는 방법을 제안하였다.

소나무재선충(Bursaphelenchus xylophilus)에 대한 몇 가지 한약재 추출물의 살선충 활성

이동운 ( Dong Woon Lee ),이상명 ( Sang Myeong Lee ),이신혜 ( Shin Hae Lee ),추호렬 ( Ho Yul Choo ) 한국토양동물학회 2010 한국토양동물학회지 Vol.14 No.1

Seventeen species (Artemisia argyi, Areca catechu, Auckulandia lappa, Atractylodes lancea, Cassia obtusifolia, Cyperus rotundus, Carthamus tinctorius, Dryopteris crassirhizoma, Eugenia caryophyllata, Lonicera japonica, Prunus mume, Piper nigrum, Quisqualis indica, Sophora flavescens, Taraxacum mongolicum, Torreya nucifera, and Zanthoxylum piperitum) in 12 families herbal hot and cold water extracts were evaluates to control pine wood nematode, Bursaphelenchus xylophilus in laboratory. Among them, hot and cold water extract of A. lancea with concentration of 10 fold showed 100% mean mortality rate against B. xylophilus at 1 day of exposure time in petri dish. With 10 fold concentration of cold water extracts of P. nigrum, Q. indica, S. flavescens and T. mongolicum and hot water extract of C. tinctorius showed 100% mean mortality rate against B. xylophilus at 1 day of exposure time too. Cold water herbal extracts with 1,000 fold concentration killed nematodes, but low efficacy to B. xylophilus. Hot water extract of P. nigrum with 500 fold concentration was the highest efficacy to B. xylophilus.

두드러기 소아 환자에서의 흡입 및 식품항원 감작과 비타민 D 관련성

이정봉 ( Jeong Bong Lee ),이신혜 ( Shin Hae Lee ),한만용 ( Man Yong Han ),윤정원 ( Jung Won Yoon ) 대한천식알레르기학회 2017 Allergy Asthma & Respiratory Disease Vol.5 No.3

Purpose: Urticaria is a common disorder, with a lifetime incidence of approximately 15%-20% of the general population. It is difficult to differentiate urticaria in children because of the similarity in symptoms between acute and chronic urticaria. There is also a lack of studies between vitamin D known as an important role in the immune system and urticaria in children. The present study aimed to assess the characteristics and allergen sensitization of young children diagnosed with urticaria and to evaluate the relationship between their vitamin D status and urticaria. Methods: We retrospectively reviewed medical records of 218 children diagnosed as having urticaria at CHA and Myongji Hospitals between April 2013 and December 2014. The results of questionnaires and laboratory tests, including specific IgE and serum 25-hydroxy vitamin D concentrations were obtained. Results: Of 218 patients, 118 (54%) were positive for at least 1 allergen and there was no significant difference in the prevalence of sensitization between the acute and chronic urticaria groups. However, the prevalence of polysensitization and sensitization of house dust mites was significantly higher in the chronic urticaria group than in the acute urticaria group (P=0.011 and P=0.029, respectively). Among the urticaria symptoms, an itching sensation was more associated with insufficient vitamin D status in children with urticaria (P=0.034). Conclusion: Our results demonstrated that children with chronic urticaria have a higher prevalence of sensitization to house dust mites and polysensitization. Further studies will need to determine whether the supply of vitamin D can improve itching sensation in urticaria children with an insufficient vitamin D status. (Allergy Asthma Respir Dis 2017:5:153-158)

호흡기 바이러스의 연령별, 성별, 계절별에 따른 유병률 변화: 단일기관에서 10년 동안 호흡기 질환으로 입원한 소아 환자를 중심으로

이승진 ( Seung Jin Lee ),이신혜 ( Shin Hae Lee ),하은교 ( Eun Kyo Ha ),신윤호 ( Youn Ho Sheen ),성명순 ( Myong Soon Sung ),정영호 ( Young-ho Jung ),이경석 ( Kyung Suk Lee ),지혜미 ( Hye Mi Jee ),한만용 ( Man Yong Han ) 대한천식알레르기학회 2017 Allergy Asthma & Respiratory Disease Vol.5 No.6

Purpose: It is well known that respiratory viral infection has epidemiological characteristics, including season. This study aimed to investigate the patterns of the prevalence of common respiratory viruses during a period of 10 years with regard to age, sex, and season in Korean children. Methods: From June 2006 to November 2016, we obtained 11,798 specimens from patients aged less than 18 years who were admitted with lower respiratory infections. Ten respiratory viruses were detected using multiplex reverse transcription-polymerase chain reaction. Results: Of 11,798 specimens, at least 1 virus was detected in 4,845 (41.1%). Respiratory syncytial virus (RSV, 18.9%) was the most common virus detected, followed by human rhinovirus (HRV, 14.8%), adenovirus (9.5%), and human bocavirus (HBoV, 7.4%). The detection rate of HRV was higher in male subjects (male 60.0% vs. female 40.0%, P=0.004), but the other viruses had no significant differences with regard to sex. The subjects who were positive for RSV test were youngest (median, 10.5 months; interquartile range, 3.0-25.0 months), followed by human coronavirus (median, 13.0 months), HRV (median, 14 months), and parainfluenza (median, 14 months). HBoV was most commonly detected in spring (29.3%), enterovirus in summer (25.8%), HRV in fall (22.6%), and RSV in October and winter (22.6%). Conclusion: We found that the prevalence of respiratory viruses in Korean children during a period of 10 years was associated with age, sex, and season when the infection occurred. Further nationwide data is warranted to infer clinical implication of our results. (Allergy Asthma Respir Dis 2017;5:320-325)

Neem과 mustard oil이 곤충병원성 선충과 누에에 미치는 영향

하판정(Pan Jung Ha),김태수(Tae Su Kim),이신혜(Shin Hae Lee),추호렬(Ho Yul Choo),최성환(Sung-Hwan Choi),김영섭(Young Sub Kim),이동운(Dong Woon Lee) 한국농약과학회 2010 농약과학회지 Vol.14 No.1

Effects of thirteen essential oils (anise oil, clove oil, marigold, mustard oil, neem oil, quassia, quilaja, rosemary oil, rotenone, tea tree extract, thyme oil, wintergreen oil, and yucca) and caffeine on typical industrial insect, silkworm (Bombyx mori) and two entomopathogenic nematodes, Steinernema carpocapsae GSN-1 strain (Sc) and Heterorhabditis sp. Gyeongsan strain (Hg) were investigated in the laboratory. When 1,000 ppm of each essential oils was treated, neem oil showed the highest insecticidal activity against silkworm. Mortality of silkworm fed on neem oil treated mulberry leaf was 55.3 and 100% 5 and 10 days after treatment, respectively. The silkworm fed on neem oil treated mulberry leaf did not make cocoon and pupa. Weight of cocoon and pupa was low in rotenone treatment showing 0.27 g and 1.01 g, respectively. Mustard oil had the highest nematicidal activity against entomopathogenic nematodes. 20 ppm of mustard oil resulted in 69.0% and 100% mortality of Sc and Hg 3 days after treatment, but 4% and 36% at 5 ppm in X-plate, respectively. Mortality of baited Galleria mellonella larva by Sc was not different from control at the concentration of 100 ppm of mustard oil while 30% lower in Hg in sand barrier. Mean numbers of established infective juveniles of Hg in Galleria larva were lower than Sc in sand barrier. Survival rate of Sc was similar to control at the concentration of <200 ppm of mustard oil in sand barrier.

파종성 결핵 환자에서 interferon-γ 수용체의 부분결핍에 관한 연구

황정혜 ( Jung Hye Hwang ),고원중 ( Won Jung Koh ),이신혜 ( Shin Hye Lee ),김은주 ( Eun Joo Kim ),강은해 ( Eun Hae Kang ),서지영 ( Gee Young Suh ),정만표 ( Man Pyo Chung ),김호중 ( Ho Joong Kim ),권오정 ( O Jung Kwon ) 대한결핵 및 호흡기학회 2005 Tuberculosis and Respiratory Diseases Vol.58 No.1

연구배경 : 결핵의 발병에 유전적인 소인이 존재하며 숙주 면역 반응에 IFN-γ가 중요한 역할을 한다고 알려져 있다. 파종성 NTM 또는 BCG 감염증 환자에서 IFN-γ 수용체 유전자 돌연변이가 밝혀져 있는데, 결핵 환자에서 IFN-γ 수용체의 부분결핍 유무는 잘 알려져 있지 않았다. 방법 : 2개 이상의 장기를 침범한 파종성 결핵 환자 6명을 대상으로 염기순서분석을 통해 IFN-γ 수용체 1과 IFN-γ 수용체 2의 부분결핍을 초래하는 유전자 이상이 Background : Interferon-gamma (IFN-γ) is essential in the immune response to mycobacterial infections, and a complete or partial deficiency in the IFN-γ receptor 1 (IFNγR1) or the IFN-γ receptor 2 (IFNγR2) have been reported to confer susceptibility to a

모바일폰에서의 멀티태스킹 사용 맥락조사

정승은(Chung Seung Eun),이정윤(Rhee Jeong Yoon),이신혜(Lee Shin Hae),류한영(Ryoo Han Young) 한국HCI학회 2009 한국HCI학회 학술대회 Vol.2009 No.2

본 연구는 모바일폰 사용자의 멀티태스킹 니즈를 중심으로 태스크간의 이동을 유추함으로써, 각 태스크 별로 멀티태스킹이 지원되어야 하는 최소의 태스크 집단을 보여주고자 진행된, 멀티태스킹을 위한 모바일폰 인터페이스 설계의 기초 연구이다. 사용자가 여러 가지 태스크가 일어나는 상황을 예측한다는 것은 어려운 일이기 때문에, 먼저 모바일폰의 기능에서 도출된 16 가지 주요 태스크 별로 일대일로 대응되는 멀티태스킹 니즈를 조사하였다. 하나의 태스크에서 멀티태스킹 니즈가 있는 태스크가 도출되며, 다시 그 태스크에 나타난 멀티태스킹 니즈를 찾아가는 유추의 방식으로 태스크 간의 이동을 간략화하여 멀티태스킹 시나리오 다이어그램을 도출하였다. 여러 개의 태스크가 동시에 일어날 때 멀티태스킹이 어떠한 과정을 통하여 나타나는 가를 체계화하는 이러한 과정은, 향후 멀티태스킹 맥락을 고려한 사용자 중심 인터페이스 개발에 적용할 수 있을 것으로 기대된다. This paper presents the minimum groups of tasks that should allow for multi-tasking by each main task when using a mobile phone. Imaging the situation that various tasks are seamlessly happened and making clear which tasks they need are not simple for users. Thus, we explore multi-tasking needs between every two tasks first, out of entire 16 functions selected from general functions that mobile phones have. Next, we create multi-tasking scenarios by analogy connecting each previous task to appropriate tasks that user's needs are revealed. In this manner, 11 scenarios are introduced finally. We expect that the result of our research is possible to be applicable to the development of user-centered design that multi-tasking contexts are considered.