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웨어러블 심전도 측정과 임상 심전도 측정과의 상관관계에 대한 연구
이강휘(Kang-Hwi Lee),이성수(Seong-Su Lee),김상민(Sang-Min Kim),이혁재(Hyeok-Jae Lee),민경진(Kyoung-Jin Min),강현규(Hyun-Kyu Kang),이주현(Joo-Hyeon Lee),곽휘권(Hwy-Kuen Kwak),고윤수(Yun-Soo Ko),이정환(Jeong-Whan Lee) 대한전기학회 2018 전기학회논문지 Vol.67 No.12
Recent advances in ICT technology have transformed many of our daily lives and attracted a lot of attention to personal health. Heart beat measurement that reflects cardiac activities has been used in various fields such as exercise evaluation and psychological state evaluation for a long time, but its utilization method is limited due to its differentiation from clinical electrocardiogram. Therefore, in this study, we could observe the change of the measured signal according to the change of the distance and the position of the measuring electrodes which are non-standard electrode configuration. Based on the electric dipole model of the heart, correlation with clinical electrocardiogram could be confirmed by synthesizing multiple surface potentials measured with a shorter electrode distance than standard one. From the electromagnetic point of view, the distance between the measuring electrodes corresponds to the distance that the electric potential by the cardiac electric dipole moves, and the electric potential measured at the body surface is proportional to the moving distance of the electric potential. Therefore, it is preferable to make the distance between electrodes as long as possible, and to position the measuring electrode close to the ventricle rather than the atrium. In addition, it was found that standard electrocardiographic waveforms could be synthesized by using arithmetic sum of multiple measuring electrodes due to the relationship of electrical dipole vectors, which is obtained by dividing and positioning a plurality of measuring electrodes on a reference electrode line, such as Lead-I, Lead-II direction. Also, we obtained a significant Pearson correlation coefficient (r = 0.9113 ± 0.0169) as a result of synthetic experiments on four subjects.
증례 : 감염 ; HIV 감염 환자에서 피부의 좁쌀결핵으로 발현한 IRIS 1예
고재훈 ( Jae Hoon Ko ),신범수 ( Beom Su Shin ),이성수 ( Seong Soo Lee ),임경숙 ( Kyung Suk Lim ),이우주 ( Woo Joo Lee ),유정래 ( Jeong Rae Yoo ),강철인 ( Cheol In Kang ) 대한내과학회 2014 대한내과학회지 Vol.86 No.5
피부의 좁쌀결핵은 면역저하 상태에서 발생하는 결핵의 드문 감염형태로, 구진 농포성 발진과 피부를 포함한 여러 장기로의 결핵균의 혈행성 다장기 감염을 특징으로 한다. 저자들은 ART를 시작한 HIV 감염 환자에서 피부의 좁쌀결핵으로 발현한 IRIS 첫 예를 경험하여 이를 보고하는 바이다. Tuberculosis is one of the most common opportunistic diseases in human immunodeficiency virus (HIV)-infected patients in Korea, and extra-pulmonary infections are frequent in these patients. Cutaneous miliary tuberculosis is a rare form of tuberculosis that presents as a papulopustular eruption and hematogenous dissemination of Mycobacterium tuberculosis to multiple organs. This has been reported in patients with progressive HIV infection. We report the first case of cutaneous miliary tuberculosis that developed as a manifestation of immune reconstitution inflammatory syndrome (IRIS) after initiating antiretroviral therapy (ART). (Korean J Med 2014;86:647-650)
송동섭(Dong Seob Song),한지연(Ji Youn Han),권희정(Hi Jeong Kwen),민기옥(Ki Ouk Min),이성수(Seong Su Lee),김현숙(Hyeon Sook Kim),서은주(Eun Joo Seo),이경식(Kyung Shik Lee),김문희(Moon Hee Kim),이은희(Eun Hee Lee) 대한내과학회 2000 대한내과학회지 Vol.58 No.6
N/A Ascites is a rare complication of multiple myeloma. When it develops, it is usually associated with extensive liver infiltration with plasma cells, infectious peritonitis or myelomatous peritoneal infiltration. Ascites caused by peritoneal infiltration is even less frequent than others. The majority of previously reported cases were characterized by an IgA paraprotein and lack of skeletal lesions. This rare extramedullary complication of myeloma has been unresponsive to therapy and rapidly fatal. Therefore, it is important to recognize myeloma as a cause of ascites and the presence of ascites heralds a poor prognosis of myeloma. We recently experienced a case of myeloma with ascites and reviewed the relevant literature of human myeloma presenting with the triad of ascites, relative or absolute sparing of the skeleton, and an IgA paraprotein. A 76-year-old man was presented with ascites early in the course of myeloma. He had no evidence of intra-abdominal plasmacytoma and skeletal lesions. Myelomatous ascites was demonstrated by the monoclonal immunoglobulin of IgA type in ascitic fluid. He was treated by plasmapheresis due to hyperviscosity syndrome and VAD combination chemotherapy. He was discharged with the improved clinical condition.(Korean J Med 58:686-691, 2000)
김영진,이성수,김정태,최호,홍윤주,이철주,노환규,류한영,소동문 대한외상학회 1997 大韓外傷學會誌 Vol.10 No.2
Traumatic cardiac rupture is high rates of morbidity and mortality. From May to June, 1997, v e experienced the five cases of traumatic cardiac rupture. In sex distribution. All 1 cases were male and ages 12 to 67. 4 cases were injured traffic accident and 1 case was stah injury. Anatomic injuries included right atrial rupture, 2 cases (40%) and left atrial rupture, 2 cases (40%) and right ventricle rupture. 1 case (20%). Diagnosis was made hy CVP check, echocardiogram, computed tomogram in case hy case. 4 cases were median sternotomy and other 1 case was left lateral thoracotomy. The immediate post operative mortality rate was only 1 case (20% ).
비외상성 두개내 출혈 환자에서 심근손상의 발생과 예후에 미치는 영향
강구현,황성호,이강현,조준휘,김성환,문중범,박해상,이서영,이성수,김헌주 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4
Objective: The aim of this study was to investigate the clinical significance of myocardial injuries in patients with nontraumatic intracranial hemorrhage by identifying the occurrence of myocardial injury and defining its correlation with subsequent cardiovascular events. Subjects and methods: One hundred twenty-four patients with nontraumatic intracraninal hemorrhage presented to the emergency department within six hours from onset of symptoms were enrolled. Brain CT, serial electrocardiography, and echocardiography were done at the emergency center. Blood samples for troponin I and creatine kinase(CK)-MB were drawn immediately and eight hours after admission, Troponin I and CK-MB were measured using a chemiluminescent immunoassay, respectively. Results: Electrocardiographic and echocardiography abnormalities were found in 65 cases(52.4%) and 21 cases(17%), respectively. Serum troponin I and creative kinase-MB were increased in 35 cases (28.2%) and in 58 cases(46.8%), respectively. Abnormal findings of echocardiography and ECG, as well as elevated levels of serum troponin I and creative kinase-MB, were associated with an increased risk of cardiovascular event and survival. Logistic regression analysis revealed that an abnormal echcocardiographic finding and elevation of serum troponin I were factors associated with the occurrence an adverse cardiovascular event and that electrocardiographic abnormalities and initial mental status were factors associated with poor prognosis. Conclusion: This study reveals that actual myocardial injury develops in a significant proportion of patients with nontraumatic intracranial hemorrhage and that the development of the myocardial injury is associated with an adverse cardiovascular event that occurs during admission.