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      • 발생 부위에 따른 단순성 골낭종의 치료방법에 대한 연구

        이석현,서승우,정현일,Lee, S.H.,Suh, S.W.,Jeong, H.I. 대한근골격종양학회 1996 대한골관절종양학회지 Vol.2 No.1

        Twenty-nine cases of unicameral bone cyst developed in long bone of children have been treated and followed up for 4.5 years in average form Department of Orthopaedic Surgery, Guro Hospital, Korea University, College of Medicine since September, 1983, Treatment for those lesions differed to form largely two groups, one of which consised of insillation of Methyl-prednisolone for non-weight bearing bones(12 humeri) and the other of curettage and autogenous bone graft for weight-bearing bones(7 femur). Methl-prednisolone group required repetition of instillation for 3.5 time in average spanning over 4 years until cloudy obliteration occurs. Curettage and bone graft had healed in 3 year 6 months' time in average. There were neither recurrence nor pathologic fractures of the lesions with the latter group. Immobilization period was virtually non with Methyl-prednisolone group and 4-6 weeks by hip spica with curettage and bone graft group. As conclusions, It seems confirmed that treatment strategy of unicameral bone cyst consisted of Methyl-prednisolone instillation for humerus lesions and early curettage and bone graft for femur lesions is applicable as guideline having solid ground in clinical experiences.

      • KCI등재

        동결-해동-원심분리를 이용한 무세포 돼지각막의 특성 연구

        이석현,전연숙,김재찬.Seok Hyun Lee. MD. Yeoun Sook Chun. MD. Jae Chan Kim. MD. PhD 대한안과학회 2011 대한안과학회지 Vol.52 No.1

        Purpose: To develop a new decellularization technique of porcine cornea using freezing-thawing-centrifugation (FTC) and to examine the characteristics of acellular porcine cornea (APC) for xenograft material. Methods: Two-hundred micrometer thickness porcine corneas were decellularized with DNase/RNase, followed by 3 freezing-thawing-centrifugations (FTC, group 1), lyophilized FTC-APC (group 2), and chemical enzyme treated APC (CE-APC, group 3). Histologic evaluation to examine cells and collagen matrix, comparison of transparency, and cultivation to determine the viability of stromal cells was performed in fresh porcine cornea and 3 experimental groups. Results: Decellularization occurred successfully in all experimental groups. Decellularization was confirmed by H&E staining and cultivation. Transparency of group 1 was similar to the normal porcine cornea but transparency of group 2 and group 3 was decreased. Collagen fibers of CE-APC (group 3) were not as well arrayed as FTC-APC (group 2). Conclusions: Acellularity of porcine cornea was successfully achieved by the FTC method with preservation of the cornea stroma. Novel decellularized porcine cornea can be considered as xenogeneic material for corneal transplantation. J Korean Ophthalmol Soc 2011;52(1):86-92

      • KCI우수등재

        국내 Holstein종에서 milk β-hydroxybutyrate acid, milk acetone, 에너지 보정유량 및 산유량의 유전모수 추정

        이석현,최성운,당창권,도창희,Lee, SeokHyun,Choi, Sungwoon,Dang, Chang-Gwon,Mahboob, Alarn,Do, ChangHee 한국데이터정보과학회 2017 한국데이터정보과학회지 Vol.28 No.6

        케토시스 질병의 지표 형질인 milk ${\beta}$-hydroxybutyratc acid (BHBA), milk acetone, 그리고 사료효율의 지표형질 에너지보정유량 및 젖소의 주요 경제 형질인 산유량에 대한 유전력과 이들 간의 유전적 관계를 통하여 젖소의 케토시스 저항성 증진 가능성을 확인하기 위하여 본 연구를 수행하였다. 국내 젖소 14,397두에서 수집된 산유능력 검정자료 75,072건의 기록과 혈통기록 44,954두의 기록을 다형질 임의회귀 검정일 선형 모형을 이용하여 분석하였다. 케토시스 지표형질들의 유전력은 범위 0.06 ~ 0.15, 평균 0.08 (${\pm}0.03$)로 추정되었으며, 케토시스 지표형질들 간에 표현형 상관은 범위 0.73 ~ 0.90, 평균 0.78 (${\pm}0.04$), 유전 상관은 0.93 ~ 0.98 평균은 0.97 (${\pm}0.01$), milk BHBA, milk acetone과 산유량의 표현형 상관은 범위 -0.18 ~ -0.05 평균 -0.08 (${\pm}0.027$), 범위 -0.05 ~ -0.23, 평균 -0.1 (${\pm}0.041$), 유전상관은 -0.55 ~ 0.05, 평균 -0.16 (${\pm}0.18$), -0.62 ~ -0.04, 평균 -0.24 (${\pm}0.17$)로 각각 추정이 되었다. mill BHBA, milk acetone과 ECM의 표현형 상관관계는 0.056 (${\pm}0.023$), -0.04 (${\pm}0.029$), 유전적 관계는 평균 0.023 (${\pm}0.08$), 0.09 (${\pm}0.067$)로 각각 추정되었다. 따라서 산유능력 검정자료 수집 시 부가적으로 수집되는 케톤체를 이용하면 케토시스 저항성 증진을 할 수 있을 것으로 사료된다. This study was conducted to estimate the genetic parameters for common ketosis indicators (${\beta}$-hydroxybutyrate acid, BHBA; milk acetone), feed intake efficiency indicator (energy-corrected milk, ECM), and milk yield (MY) in Korean Holstein. A total of 75,072 monthly test-day records from 14,397 first parity cows were collected, between 2012 and 2016, from Korea animal improvement association enrolled farms. Variance components were estimated using a multiple trait random regression model. The heritability of BHBA and acetone levels ranged from 0.06 to 0.15 at different DIMs. The phenotypic and genetic correlations between BHBA and acetone were between 0.73 and 0.90, and between 0.93 and 0.98, respectively. The phenotypic correlation between BHBA and MY, between acetone and MY, between BHBA and ECM, and between acetone and ECM ranged from -0.18 to -0.05, -0.23 to -0.05, 0 to 0.10, and -0.09 to 0.01, respectively. Genetic correlation estimates between BHBA and MY, between acetone and MY, between BHBA and ECM, and between acetone and ECM also ranged from -0.55 to 0.05, -0.62 to -0.04, -0.10 to 0.11, and -0.20 to 0.00, respectively. We hope that these results would greatly assist in the improvement of ketosis disease in the local Holsteins.

      • KCI등재

        편측성 후방연장 국소의치에서 직접유지장치의 설계와 지대치 골흡수에 따른 간접유지장치 지대치 주위조직에 발생하는 응력분석

        이석현,이청희,조광헌,Lee, Suk-Hyun,Lee, Cheong-Hee,Jo, Kwang-Hun 대한치과보철학회 1998 대한치과보철학회지 Vol.36 No.1

        For the purpose of evaluating the effect of both direct retainer design and bony absorption degree around abutment of indirect retainer on the supporting tissue of abutment of indirect retainer, dislodging force was transmitted to unilateral distal extension RPD bases. Analysis of stress distributed within the supporting tissue around abutment of indirect retainer was carried out. Using three-dimensional photoelastic stress analysis method and the conclusion is a follows. 1. According to the extent of force which the direct retainer of the most distal abutment tooth, the amount of force transmitted to the abutment tooth of indirect retainer was small. 2. Of all the cases, Mandibular first premolar which was used abutment tooth of indirect retainer, buccal, mesial and distal sides represented compression stress and lingual side represented tensile stress. 3. The more bone resorption of abutment tooth of indirect retainer, the more distortion of buccal and distal side of abutment tooth was existed and the extent of compression stress which was existed and distal side to abutment tooth was large. 4. When the alveolar bone around the abutment with indircet retainer is normal. The amount of force transmitted on abutment with indirect retainer was small in the order of Akers clasp, RPA clasp, RPI clasp. 5. When the alveolar bone around the abutment with indirect retainer has been absorbed 20% and 30%, the amount of force transmitted on abutment with indirect retainer was small in the order of RPA calsp, RPI clasp, Akers clasp. 6. When denture is displaced, shape of the direct retainer reciprocating abutment affect much the function of indirect retainer.

      • 인천광역시 원도심 공원녹지 기본계획 현황 및 이용 평가

        이석현,김하늘,곽동화,Lee, Seok-Hyun,Kim, Haneul,Kwack, Dongwha 인천대학교 도시과학연구원 2018 도시과학 Vol.7 No.2

        The purpose of this study is to review and evaluate the proper planning for 2030 Incheon Urban Parks & Green Space Master Plan. Some of the plans are aimed at multiple small districts within the city's old town, as local governments are planned to be sub-subsidized by Incheon Metropolitan City. However, these plans have become simple plans for each district and therefore find it difficult to collect from the perspective of the using system of the residents who are directly used. First, the construction of the urban park and green space network requires the construction of a service using system that can be felt by the users. Second, the basic idea of each district planned as the detailed strategy of the master plan should be planned through consultation with nearby the district. Third, specific targets and directions for the urban park and green space plan through the urban development project are needed.

      • KCI등재

        교수에 대한 수학적 지식의 관점에서 본 지필평가문항 분석

        이석현,한길준,Lee, Seok-Hyeon,Han, Gil-Jun 한국수학사학회 2012 Journal for history of mathematics Vol.25 No.2

        본 연구는 평가 문항에 대한 컨설팅 내용을 '교수에 필요한 수학적 지식 (MKT)'의 영역과 비교하여 '평가 문항 제작에 필요한 지식'의 영역을 알아볼 목적으로 2007년부터 2009년까지 A교육청의 컨설팅단에서 일선학교 교사들이 출제한 문항에 대해 컨설팅을한 내용을 수집하여 분석하였다. 이를 통하여 '평가 문항 제작에 필요한 지식'을 알아보았으며 교사들이 보다 질 높은 평가 문항을 제작할 수 있도록 하기 위해서는 문항 출제 관련 연수 및 컨설팅이 계속해서 이루어질 필요가 있다고 판단된다. This paper aims to identify the area of knowledge required for constructing test items by comparing the consulting contents with the area of MKT(Mathematical Knowledge for Teaching). This paper collects the consulting results by the consulting group of A provincial office of education from 2007 to 2009, and analyzes and categorizes the results. The knowledge for constructing test items are known by the analysis on the consulting contents. Training and consulting for teachers are necessary to enable them to recognize the importance of these categories and improve the quality of test items.

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