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        「최척전」에 나타난 지리산권의 역사와 삶

        이상구 순천대학교 남도문화연구소 2011 南道文化硏究 Vol.0 No.21

        Little resources have been left on the situation and terrific condition of Mt. Jiri district duing the Imjin War and Jeongyu War in the late 16th century. Gyeongyeom(慶念), a war accompanying monk, left 『Dairy in Joseon(朝鮮日日記)』and Jo Gyeong Nam(趙慶男) left, 『Miscellaneous during the war(亂中雜錄)』. However, 「Choicheokjeon」 reveals no less the severity of the war than these resources whose records correspond with the historical fact. It is, of course, hard to figure out overall feature and progress of the war as 「Choicheokjeon」 is based on specific individual's experience. This is the unique point of 「Choicheokjeon」 to others. 「Choicheokjeon」 is dramatized an actual experience, which describes helpless situation and emotional feeling one suffered specifically and delicately. With this point in mind, this study examines the details of 「 Choicheokjeon」 with historical fact and resources to figure out its authenticity and the life of residents in Mt. Jiri district. As a result, it proves that the contents and incidents in 「Choicheokjeon」 in the late 16th century are corresponding to historical facts to a great extent, and it also shows a history and life of Mt. Jiri including the brutality of Japanese troops and the life of local gentry in Namwon.

      • KCI등재

        거시경제요인이 보건의료산업 주식시장에 미치는 영향에 관한 연구

        이상구 대한경영정보학회 2015 경영과 정보연구 Vol.34 No.4

        본 연구의 목적은 보건의료산업 주식 시장에 대해 거시경제변수에 대한 요인이 미치는 영향을 알아보고자 한다. 첫째, 의약품지수는 국공채금리와 환율을 원인변수로 하며 콜금리변수와는 상호영향 관계를 가진다. 즉 금리와 환율의 변화는 의약품산업에 영향을 미치는 변수로서 주의해야 한다는 것이다. 둘째, 의료기기지수는 콜금리, 국공채금리, 환율에 대해 상호 원인변수로 작용하며 경상수지변수를 원인변수로 한다. 즉 의료기기산업에 대해 금리와 환율 그리고 경상수지의 변화가 영향을 미칠 수 있다는것이다. 셋째, 의약품 지수에 영향을 미치는 변수의 관계를 추가적으로 분석하면 콜금리와 환율은 음(-)의 관계이며 국공채금리와는 양(+)의 관계를 가진다. 의료기기 지수에 영향을 미치는 변수의 관계를 분석하면환율과는 음(-)의 관계이며 국공채금리와는 양(+)의 관계를 가진다. The purpose of this study was to evaluate the effect of this factor on the macroeconomic variables for the healthcare industry market. First, the government bond interest rates and the exchange rate is the cause variable of drug industry index. Drug industry index is a mutual influence between the Call interest rate. Second, the medical equipment index haver mutual cause variable such as call rate index, government bond interest rates, and exchange rate. A current account balance variable is the cause variable of drug industry index. Third, the drug industry index has a negative relationship with a Call interest rate and an exchange rate. but it has a positive relationship with a government bond interest rates. the medical equipment index has a negative relationship with an exchange rate. but it has a positive relationship with a government bond interest rates.

      • KCI등재

        구강 편평세포암종에서 태반성장인자의 발현

        이상구,김철환,Lee, Sang-Gu,Kim, Chul-Hwan 대한악안면성형재건외과학회 2009 Maxillofacial Plastic Reconstructive Surgery Vol.31 No.1

        Angiogenesis is essential for solid tumor growth and progression. Among the pro-angiogenetic factors, vascular endothelial growth factor(VEGF), also known as vascular permeability factor, is the most important as a mitogen for vascular endothelium. The VEGF family of molecules currently consists of six growth factors, VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and placenta growth factor(PlGF). Over-expression of PlGF is associated with angiogenesis under pathological conditions such as ischemia, inflammation, and cancer. Hence, the goal of this study is to identify the correlation of clinicopathlogical factors and the up-regulation of PlGF expression in oral squamous cell carcinoma. We studied the immunohistochemical staining of PlGF, PlGF gene expression and a real time quantitative RT-PCR in 20 specimens of 20 patients with oral squamous cell carcinoma. The results were as follows. 1. In the immunohistochemical study of poorly differentiated and invasive oral squamous cell carcinoma, the high level staining of PlGF was observed. And the correlation between immunohistopathological PlGF expression and histological differentiation of specimens was significant (Pearson correlation analysis, significance [r] >0.6, P < .05). 2. In the PlGF gene RT-PCR analysis, PlGF expression was more in tumor tissue than in adjacent normal tissue. Paired-samples analysis determined the difference of PlGF mRNA expression level between the cancer tissue and the normal tissue (Student's t - test, P < .05) These findings suggest that up-regulation of the PlGF gene may play a role in progression and local metastasis in invasive oral squamous cell carcinoma.

      • KCI등재

        20세기 초 미국수학계의 혁명적변화의 바탕

        이상구,황석근,천기상,Lee, Sang-Gu,Hwang, Suk-Geun,Cheon, Gi-Sang 한국수학사학회 2007 Journal for history of mathematics Vol.20 No.3

        미국수학사에서 가장 중요한 시기로 여겨지는 1890년에서 1950년 사이의 미국수학계의 발전과정을 당시의 미국수학 연구에 있어서 혁신적 발전의 계기를 제공한 시카고 대학의 초대 수학과장 E.H. Moore 의 역할을 중심으로 고찰한다. 19세기말 아직 낙후되었던 미국 수학계는 시카고 대학의 핵심 학과였던 수학과는 총장의 비전을 같이 할 우수교수를 확보하고, 새로운 제도 하에서 선발된 우수 대학원 학생들을 탐구지향 교수법으로 지도하며 미국 수학연구의 초장기에 우수한 인재를 공급하기 시작한다. 이를 통하여 미국은 인재양성과 새로운 연구 분야 및 연구방법의 개척에 성공하고, 1950년 국제수학자대회(ICM)를 미국에서 개최하며, 당당히 세계수학의 주류에 진입한다. 본 원고는 위의 발전과정이 현재 한국에 주는 의미를 분석한다. From 1876 to 1883, British mathematician James Joseph Sylvester worked as the founding head of Mathematics Department at the Johns Hopkins University which has been known as America's first school of mathematical research. Sylvester established the American Journal of Mathematics, the first sustained mathematics research journal in the United States. It is natural that we think this is the most exciting and important period in American mathematics. But we found out that the International Congress of Mathematicians held at the World's Columbian Exposition in Chicago, August 21-26, 1893 was the real turning point in American's dedication to mathematical research. The University of Chicago was founded in 1890 by the American Baptist Education Society and John D. Rockefeller. The founding head of mathematics department Eliakim Hastings Moore was the one who produced many excellent American mathematics Ph.D's in early stage. Many of Moore's students contributed to build up real American mathematics research power in early 20 century The University also has a well-deserved reputation as the "teacher of teachers". Beginning with Sylvester, we analyze what E.H. Moore had done as a teacher and a head of the new department that produced many mathematical talents such as L.E. Dickson(1896), H. Slaught(1898), O. Veblen(1903), R.L. Moore(1905), G.D. Birkhoff(1907), T.H. Hilderbrants(1910), E.W. Chittenden(1912) who made the history of American mathematics. In this article, we study how Moore's vision, new system and new way of teaching influenced American mathematical society at early stage of the top class mathematical research. and the meaning that early University of Chicago case gave.

      • KCI등재

        흰띠명나방의 온도발육 모형

        이상구,김주,정성수,김연국,이상계,황창연,Lee, Sang-Ku,Kim, Ju,Cheong, Seong-Soo,Kim, Yeon-Kook,Lee, Sang-Guei,Hwang, Chang-Yeon 한국응용곤충학회 2013 한국응용곤충학회지 Vol.52 No.1

        비트의 주요 해충인 흰띠명나방을 9개의 다른 온도조건(15.0, 17.5, 20.0, 22.5, 25.0, 27.5, 30.0, 32.5 및 $35.0^{\circ}C$), 상대습도 $65{\pm}5%$, 광조건 16L:8D에서 발육특성을 조사한 결과, 알에서 성충 우화 전까지의 발육기간은 $17.5^{\circ}C$에서 51.0일로 가장 길었고, $35^{\circ}C$에서 14.6일로 가장 짧게 조사되었다. 온도와 발육율의 관계를 직선회귀에 의해 분석한 결과, 결정계수($R^2$) 값이 0.87 이상으로 나타났으며, 온도에 따른 발육은 직선회귀에 부합되었다. 알부터 성충 우화 전까지의 발육영점온도와 유효적산온도는 $10.4^{\circ}C$와 384.7일도를 나타내었다. 각 태별 발육모형은 $R^2$값이 0.97~0.99로 비선형회귀식에 잘 부합되었다. 각 태별 발육누적분포와 발육기간에 대한 평균 발육기간으로 나눈 값을 Weibull 함수에 적용한 결과 $r^2$값이 0.63~0.87이었다. The Hawaiian beet webworm (Spoladea recurvalis) is one of the serious insect pests found on red beet (Beta vulgaris var. conditiva) in Korea. The study was conducted to investigate the development period of S. recurvalis at various constant temperatures, 15.0, 17.5, 20.0, 22.5, 25.0, 27.5, 30.0, 32.5 and $35.0^{\circ}C$, with $65{\pm}5%$ RH and a photoperiod of 16L:8D. The developmental period from egg to pre-adult was 51.0 days at $17.5^{\circ}C$ and 14.6 days at $35.0^{\circ}C$. The developmental period of S. recurvalis was decreased with increasing temperature. The relationship between the developmental rate and temperature was fitted well by linear regression analysis ($R^2{\geq}0.87$). The lower developmental threshold and effective accumulative temperature of the total immature stage were $10.4^{\circ}C$ and 384.7 degree days, respectively. The nonlinear relationship between the temperature and developmental rate was well described by the Lactin model. The relationship between the cumulative frequency and normalized distributions of the developmental period for each life stage were fitted to the Weibull function with $R^2=0.63{\sim}0.87$.

      • KCI등재

        Zinc 수용액이 구강 미생물에 미치는 영향

        이상구,김은숙,이승우 대한안면통증구강내과학회 1998 Journal of Oral Medicine and Pain Vol.23 No.4

        This experiment was performed to investigate effects of zinc containing solution on the major normal flora Staphylococccus aureus, Streptococus mutans and Candida albicans and to observe the variation according to anionic change and concentration difference. Zinc chloride, zinc iodide and zinc acetate solution were added to werially diluted broth culture so that each final concentration might be 0.25%, 0.5%. 1%. After that, 100ul of each aliquot was spreaded on each selective media plate( Mannitol Salts Agar plate for Staphylococcus aureus, Mitis Salivarius Agar plate for Streptococcus mutans and Sabouraud Destrose Agar plate for Candida albicans). The % killing was calculated bu CFU count after incubation under the appropriate condition. 1. zinc iodide, zinc chloride, and zinc acetate solutions showed inhibitory effects on Staphylococcus aureus, Streptococcus mutans and Candida albicans. 2. The inhibitory effects on Staphylococcus aureus were ranked in order of ainc iodide, zinc chloride and zinc actate. 3. The inhibitory effects on Streptococcus mutans were ranked in orfer of zinc iodide, zinc chloride and zinc acetate. 4. the inhibitory effects on Candida albicans showed no difference among zinc iodide, zinc chloride and zinc acetate. 5. The inhibitory effects of zinc chloride and zinc acetate on Staphylococcus aureus and Streptococcus mutnas showed increasing pattern as the concentration increase. But the inhibitory effects of zinc iodide on Staphylococcus aureus and Streptococcus mutans showed no apparent difference according to concentrations and it was the case with the inhibitory effects of zinc iodide, zinc chloride and zinc acetate on Candida albicans.

      • KCI등재

        구취의 심도에 따른 치료 효과에 대한 비교 연구

        이상구,고홍섭,이승우 대한안면통증구강내과학회 1998 Journal of Oral Medicine and Pain Vol.23 No.3

        Considering various factors contributing oral malodor, the accurate prediction of prognosis is very important to both clinician and patients. The present study has been performed to invetigate the relationship between treatment effeicacy and pre-treatment volatile sulfur compounds (VSC) level. Ninety patients were divided into three groups, A(<150ppb), B(150< <200ppb), and C(>200ppb) groups, according to pre-treatment VSC level detected by Halimeter, and each group included 30 patients. Routine therapeutic measures for oral were provided to each patient which consisted of oral prophylaxis, tooth brushing and flossing instruction, tongue scraping by proper device, and gargling of 0.25% ZnCl2 Solution. The group with high pre-treatment VSC level (>150ppb) showed significant reduction of VSC level at 1 and 3 weeks after. However, the group with low pre-treatment VSC level (<150ppb) did not show any significant reduction during the experimental periods. Collectively, the results suggested that patients with high pre-treatment VSC level show better prognosis.

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