실험적 성대마비 개에서 자가이개연골의 성대근육내 주입 후 조직학적 변화 : 2년 후 결과

이병주,이진춘,전경명,고의경,노환중,이창훈,왕수건,Lee Byung-Joo,Lee Jin-Choon,Chon Kyong-Myong,Goh Eui-Kyung,Roh Hwan-Jung,Lee Chang-Hun,Wang Soo-Geun 대한후두음성언어의학회 2005 대한후두음성언어의학회지 Vol.16 No.2

Background and Objective : Vocal fold augmentation by injectable material under direct visual control is an easy and simple operation. However, when autologous fat or bovine collagen is used, the resoiption creates a problem. And autologous fascia is debating about absorption now days. We previously reported on the one year results of injected autologous auricular cartilage for volumetric augmentation in paralyzed canine vocal cord. This study evaluates the long-term histomorphologic results of injected autologous auricular cartilage for the augmentation of the paralyzed canine vocal fold at two year. Material and Methods . A prospective trial of autologous cartilage augmentation of vocal cord in animal model. Three dogs were operated upon. A piece of auricular cartilage was harvested from the ear and minced into tiny chips with a scalpel. Fat was harvested from inguinal area and minced with a scalpel. The minced cartilage and fat-paste (0.2ml) was injected using a pressure syringe into the paralyzed thyroarytenoid muscle using direct laryngoscopy. Three animals were sacrificed at 2 years. Each subject underwent laryngectomy and serial coronal sections of paraffin blocks from the posterior vocal fold were made. Results There was no significant complication perioperatively and during follow-up. The injected cartilage which appeared to have lost viability existed in the vocalis muscles until 24 months. Fibrotic change was exhibited in the surrounding injected cartilage. Conclusion : The autologous auricular cartilage graft is well tolerated and may be very effective material for volumetric augmentation on paralyzed vocal cord.

성대 반흔에 대한 기초연구의 최신 경향

이병주,Lee, Byung-Joo 대한후두음성언어의학회 2012 대한후두음성언어의학회지 Vol.23 No.1

Vocal fold scar disrupts structure of lamina propria and causes significant change in vocal fold tissue biomechanics, resulting in a range of voice problems that often significantly compromise patient quality of life. Although several therapeutic management have been offered in an attempt to improve vocal fold scar, the ideal treatment has not yet been found. Recently, several tissue engineering technique for vocal fold scar using growth factors, several cells, and scaffolds have been described in tissue culture and animal models. Several growth factors such as hepatocyte growth factor, basic fibroblast growth factor, and transforming growth factor beta 3 for therapy and prevention of vocal fold scar have been studied. Cell types to regenerate vocal folds in scarring tissue have been introduced autologous or scarred vocal fold fibroblast and adult mesenchymal stem cells. Decellularized organ matrix and several hyaluronic acid materials have used as scaffolds for vocal fold scar.

옥천대(沃天帶)의 변형특성(變形特性)과 그 형성(形成) 과정(過程) -충북(忠北) 남서단(南西端)을 예(例)로 하여-

이병주,박봉순,Lee, Byung-Joo,Park, Bong-Soon 대한자원환경지질학회 1983 자원환경지질 Vol.16 No.2

The studied area is situated in tho southern part of the Ogcheon fold belt, where the "Ogcheon Group" is widespread with Jurassic and Cretaceous intrusions. The regional stratigraphy may be divided into three formations, the lower pebble bearing phyllitic, the middle dark grey phyllitic, and the upper black phyllitic formations. For the purposes of the present study, the area has been partitioned to three structural subareas based on major fold axes and fault line. The main subjects of the research have been discussed from two different points, multiple deformation and minor-micro fold styles. The former is analyzed by pebble elongation, folding and lineation in a pebbly formation as well as schistosity, crenulation cleavage and crenulated lineation in the phyllitic formation. The later describes the characteristic features of fold style in each formation and structural subarea. Although minor fold axes within broad pelitic rocks usually tend to trend northeast and to plunge northward, most of these were probably formed by two stages, first a similar fold phase and second a kink fold phase. Measured structural elements indicate that crenulation cleavage in phyllite formed parallel to fold axes of folded pebble followed a NE phase of first deformation and a fold axes of pebbles diagonal to bedding of phyllite are represented by a NW phase of a second deformation. Microscopically, quartz and mica grains form a micro fold enabling one to establish tectonic levels which occur in different deformation modes in each stratigraphic sequence. Microtextures such as crenulation cleavage, kink band, aggregate band of mica and pressure shadows of porphyroblast of quartz related to qarnet and staurolite may suggest the time relation of crystallization and tectonism. The result of this study may conform that three deformation phase, NE first phase-NE second phase-NW phase, occurred in the area.

고속 WPAN의 Mesh 네트워킹을 위한 분산형 채널타임 할당

이병주,박무성,이승형,최웅철,정광수,Lee, Byung-Joo,Park, Moo-Sung,Rhee, Seung-Hyong,Choi, Woong-Chul,Chung, Kwang-Sue 한국통신학회 2007 韓國通信學會論文誌 Vol.32 No.3A

본 논문에서는 IEEE 802.15.3 High-Rate WPAN(Wireless Personal Area Network)의 메쉬 네트워크 구성을 위한 분산형 채널 자원 관리 방법을 제안한다. IEEE 802.15 TG(task group)5는 WPAM의 메쉬 네트워크 구성을 위해 MAC과 PHY 계층의 표준화를 진행중이다. 기존 WPAN에서 전송 파워의 증가나 수신측의 감도 증가없이 전송 범위 확장 방법의 연구와 네트워크 내에서 라우팅 기능의 강화를 통해서 보다 신뢰성 있는 통신을 가능케하는 것이 이 TG의 목표이다. 본 논문은 PNC(piconet coordinator)가 없이 각 DEV(device)들이 자신의 채널 자원을 예약하는 환경에서 DEV들이 공평하게 채널 자원을 사용하는 방법을 제안한다. 채널자원을 분배하는 PNC가 없으면 각 DEV는 자신이 사용할 채널자원을 미리 예약하여 사용한다. Piconet에 먼저 접속한 DEV는 많은 양의 채널자원 예약이 가능하지만 나중에 접속한 DEV는 상대적으로 적은 양의 채널자원만 예약할 수 있다. 이처럼 기존 방법에서는 DEV들이 공평하게 채널자원을 사용하지 못하는 문제점이 발생한다. 본 논문에서는 MAC 계층에서 채널 자원 할당의 불공평함을 해결하는 분산형 채널타임 할당 방법을 제안하고, 시뮬레이션을 통해서 자원 할당 방법의 성능을 평가한다. This paper presents a resource management mechanism for the mesh networking in IEEE 802.15.3 High-rate WPAN. IEEE 802.15 TGS is standardizing the MAC and PHY for mese networking. This task group researches the mechanism that are extension of network coverage without increasing transmit power of receive sensitivity, and studies the enhanced reliability via route redundancy. In this paper we propose the distributed resource management scheme that is fairly using the channel resource in the piconet without centralized piconet coordinator. Each DEV reserves the channel time and broadcasts its information. This scheme has unfairness for later associated DEV because of preoccupation of earlier associated DEVs. This paper presents the method that fairly allocates the channel time in MAC layer. And we evaluate the performance enhancement using simple simulations.

포항분지내 지각변형 해석

이병주,송교영,Lee, Byung-Joo,Song, Kyo-Young 대한자원환경지질학회 1995 자원환경지질 Vol.28 No.1

Tertiary Pohang basin distributed in south western part of the Korean peninsula, is composed of Chunbuk formation as the basal conglomerate, Hakjon formation, Duho formation and intrusive basalt having 15 Ma by absolute age data. The basement of the basin is represented to Cretaceous sedimentary rocks, Hakjon welded tuff and Chilpo welded tuff and rhyolite. The fault systems in the basement of Tertiary Pohang basin are consist of $N20^{\circ}E$ fault, $N60^{\circ}W$ and E-W trend. NNE fault is not only strike-slip but also normal dip-slip. WNW fault has sinistral strike-slip sense and the geometry of E-W fault is strike-slip and normal faults. In the basin, the fault system is represented to $N20^{\circ}E$ strike-slip, E-W normal and NNE thrust faults. By these fault relationship and geometry, it is interpreted that NNE sinistral strike-slip fault and N-S normal faults have acted at the Cretaceous basement. After Miocene NNE dextral strike-slip fault has acted and created E-W normal fault. Progressively Tertiary basin was influenced by the transpression to make thrust and fold, namely inversion tectonics.

중추신경계 손상환자의 운전자 재활에 대한 인식과 필요성 연구

이병주,신화경,이관섭,Lee, Byung-Joo,Shin, Hwa-Kyung,Lee, Kwan-Sub 대한물리치료학회 2013 대한물리치료학회지 Vol.25 No.5

Purpose: For patients with CNS injury who are restricted in the use of public transportation, car driving means more than simple movements and is essential for their independent lives, such as participation in society and returning to jobs. Therefore, in order to enhance the quality of life of disabled persons, their high perception and necessity of driving rehabilitation are required. The purpose of this study is to determine the perception and necessity of driver rehabilitation in patients with CNS injury. Methods: In order to survey the perception of patients with CNS injury and necessity of driving rehabilitation, questionnaires were distributed to patients with CNS injury. Questionnaires were composed of demographic characteristics, disability related characteristics, and driver's license related characteristics. Results: Our results showed that the number of driving participants with a driver's license for the disabled was significantly higher than that for non- driving participants with a previous general driver's license in the perception of driving rehabilitation. Conclusion: We suggest that driving rehabilitation for patients with CNS injury should be supported in terms of evaluation and treatment.

소아의 단안 고도 근시성 부등시 눈에서 콘택트렌즈 착용과 약시 치료

이병주,김정훈,유영석,Byung Joo Lee,Jeong Hun Kim,Young Suk Yu 대한안과학회 2010 대한안과학회지 Vol.51 No.1

Purpose: To report the clinical outcome of children with unilateral high myopic anisometropic amblyopia who were treated with contact lenses (CL). Methods: Patients who had myopic anisometropia greater than -7 diopters and was treated with contact lenses combined with occlusion therapy during the period between 1998 and 2007 were retrospectively reviewed. Twenty-seven patients who were followed up for more than 1 year after treatment were included in the study. Initial and final best corrected visual acuities (BCVA) were compared and factors which influence the visual outcome were analyzed. Results: A total of 10 out of 27 patients (37%) acquired visual improvement of more than 2 lines. At the final examination, 6 patients (22.2%) had BCVA better than logMAR 0.3 and 10 patients (37.0%) had BCVA better than logMAR 0.7. Medullated nerve fiber and strabismus were the most commonly associated ocular pathologies among the patients. Patients without strabismus or medullated nerve fiber acquired greater visual improvement than patients with these comorbidities. Patients with lower initial refractive error (spherical equivalent) in the amblyopic eye acquired a better final vision. Poor compliance to CL wearing or occlusion therapy adversely affected the final vision. Conclusions: In the present study of children with unilateral severe myopic anisometropic amblyopia treated with CL combined with occlusion therapy, a third of the patients acquired visual improvement of more than 2 lines. The absence of medullated nerve fiber or strabismus was determined to be a good prognostic factor. J Korean Ophthalmol Soc 2010;51(1):88-94

역류증상지수와 역류소견점수의 타당성과 신뢰도

이병주,왕수건,이진춘,Lee, Byung-Joo,Wang, Soo-Geun,Lee, Jin-Choon 대한후두음성언어의학회 2007 대한후두음성언어의학회지 Vol.18 No.2

Laryngopharyngeal reflux (LPR) is the retrograde movement of gastric contents into the larynx, pharynx, and upper aero-digestive tract. LPR differs from gastroesophageal reflux in that it is often not associated with heartburn and regurgitation symptoms. Otolaryngological manifestations of acid reflux include a wide range of pharyngeal and laryngeal symptoms. Belafsky et al. developed a useful self-administered tool, the reflux symptom index (RSI), for assessing the degree of LPR symptoms. Patients are asked to use a 0 to 5 point scale to grade the following symptoms: 1) hoarseness or voice problems; 2) throat clearing; 3) excess throat mucus or postnasal drip ; 4) difficulty swallowing; 5) coughing after eating or lying down; 6) breathing difficulties ; 7) troublesome or annoying cough; 8) sensation of something sticking or a lump in the throat; 9) heartburn, chest pain, indigestion or stomach acid coming up. A RSI score greater than 13 is considered abnormal. As there is no validated instrument to document the physical findings and severity of LPR, Belafsky et al. developed an eight-item clinical severity scale for judging laryngoscopic finding, the reflux finding score (RFS). They rated eight LPR-associated findings on a scale from 0 to 4 : subglottic edema, ventricular obliteration, erythema/hyperemia, vocal-fold edema, diffuse laryngeal edema, posterior commissure hypertrophy, granuloma/granulation tissue, and thick endolaryngeal mucus. A RFS score of greater than 7 was found to suggest LPR-associated laryngitis. Although both indices (RSI and RFS) are widely used, there is some controversy about their validity (sensitivity and specificity) and reliability (intra-rater and inter-rater) in LPR diagnosis and treatment. We discuss the validity and reliability of RSI and RFS with literature review.

IEEE 802.15.3 Wireless PAN의 MAC에서 다중채널의 적용

이병주,이승형,최웅철,정광수,이장연,조진웅,Lee Byung-Joo,Rhee Seung Hyong,Choi WoongChul,Chung Kwangsue,Lee Jang-Yeol,Cho Jin-Woong 한국통신학회 2005 韓國通信學會論文誌 Vol.30 No.8A

본 논문에서는 IEEE 802.15.3 High-Rate WPAN (Wireless Personal Area Network) 환경에서 다중 채널을 사용하여 향상된 성능의 MAC 프로토콜을 제안한다. IEEE 802.15.3 High-Rate WPAN은 10m 내외의 거리에서 실시간 비디오 및 대용량 파일 전송을 목적으로 설계된 MAC과 PHY의 표준을 말한다. 현재 표준의 MAC 프로토콜은 하나의 무선 채널을 piconet 내의 모든 DEV가 공유하여 사용한다. 이 중 PNC(Piconet Coordinator)는 TDMA(Time Division Multiple Access)방식으로 DEV들에게 채널타임을 할당한다. 이런 경우 piconet내의 통신하는 DEV의 수가 많아지게 되면 superframe의 길이가 길어져 전송되는 데이터의 aggregate throughput이 떨어지고 QoS(Quality of Service)를 보장하지 못한다. 본 논문에서 하나의 piconet이 여러 개의 채널을 동시에 사용하여 aggregate throughput을 향상시키고 QoS를 보장하는 다중채널 MAC 프로토콜을 제안하고 시뮬레이션을 통해 향상된 성능을 증명한다. This paper presents a multi-channel enhancement scheme for the MAC protocol of IEEE 802.15.3 High-rate WPAN (Wireless Personal Area Network). The current MAC protocol of the IEEE 802.15.3 High-rate WPAN is designed for sharing a single channel among DEVs of a piconet; that is, within a single piconet, PNC prevents interference through MAC layer assignment of time slots to other DEVs using time-division multiple access. When the number of DEVs that communicate with each other frequently, is increased in a single WPAN, the size of the superframe becomes inevitably large, and this may result in a significant throughput drop or a failure to provide QoS guarantee. A multi-channel enhancement scheme for the MAC protocol of IEEE 802.15.3 High-rate WPAN is proposed to significantly increase the aguegate throughput and more reliably provide the QoS guarantees in a piconet

沃川帶의 變形特性과 그 形成 過程

Byung Joo Lee(李炳柱),Bong Soon Park(朴奉淳) 대한자원환경지질학회 1983 자원환경지질 Vol.16 No.2

The studied area is situated in the southern part of the Ogcheon fold belt, where the “Ogcheon Group” is widespread with Jurassic and Cretaceous intrusions. The regional stratigraphy may be divided into three formations, the lower pebble bearing phyllitic, the middle dark grey phyllitic, and the upper black phyllitic formations. For the purposes of the present study, the area has been partitioned to three structural subareas based on major fold axes and fault line. The main subjects of the research have been discussed from two different points, multiple deformation and minor-micro fold styles. The former is analyzed by pebble elongation, folding and lineation in a pebbly formation as well as schistosity, crenulation cleavage and crenulated lineation in the phyllitic formation. The later describes the characteristic features of fold style in each formation and structural subarea. Although minor fold axes within broad pelitic rocks usually tend to trend northeast and to plunge northward, most of these were probably formed by two stages, first a similar fold phase and second a kink fold phase. Measured structural elements indicate that crenulation cleavage in phyllite formed parallel to fold axes of folded pebble followed a NE phase of first deformation and a fold axes of pebbles diagonal to bedding of phyllite are represented by a NW phase of a second deformation. Microscopically, quartz and mica grains form a micro fold enabling one to establish tectonic levels which occur in different deformation modes in each stratigraphic sequence. Microtextures such as crenulation cleavage, kink band, aggregate band of mica and pressure shadows of porphyroblast of quartz related to qarnet and staurolite may suggest the time relation of crystallization and tectonism. The result of this study may conform that three deformation phase, NE first phase-NE second phase-NW phase, occurred in the area.