Isonicotinic acid hydrazide의 in vitro 및 in vivo 적용이 nicotinamide adenine dinucleotide analogue 형성에 관한 연구

유석형 中央醫學社 1940 中央醫學 Vol.9 No.6

Insonicotinic acid hydrazide (INH), a potent anti-tuberculous compound, was first reported to form a INH analogue with nicotinamide adenine dinucleotide (NAD) in the tissue homogenate by Zatman et al., and it was suggested that the formation of such a INH analogue may be of significance in explaining the clinical anti-tuberculous action of INH. The species specificity of the animal NADase with respect to INH analogue formation was also reported. It is possible that both the "sensitive" and "insensitive" NADases react in the same manner to the INH and from INH analogue of NAD, and in case of the "insensitive" such a analogue is formed in relative large amounts. The knowledge on the human tissue NADase with respect to INH is still very poor except a few references on the prostata and spleen NADase is available, and much desired to be studied. The author made a study on the formation of INH analogue of NAD in human erythrocytes, as well as cell free systems of mouse liver, spleen, brain and lung. 1. In vitro formation of INH analogues of NAD in human erythrocyte homogenate and in subcellular fractions of mouse liver has been demonstrated. 2. In the subcellular fractions of mouse liver, the main part of the synthetic activity of INH analogue of NAD was found in motochondrial and soluble fractions. 3. The transglucosidase activity of NADase from human erythrocytes was demonstrated by measuring the ability of the homogenate of erythrocytes to synthesize isonicotinic acid hydrazide adenine dinucleotide. 4, The NADase of human erythrocytes is relatively "insensitive" to INH. 5. The tissues-i. e. liver, brain, spleen and lung, which were pretreated in vivo with NAD, give rise a high synthetic activity of formation of INH analogue of NAD, while the activity in the control group is much lower.

시인의 자아와 창조적 상상력 : W. B. Yeats의 “Among School Children”을 중심으로

유석형 한국예이츠학회 1999 한국예이츠 저널 Vol.11 No.-

In this paper, through appreciating one of W. B. Yeats’s later poems, I try to find how the poet’s creative self gets to have its creative power and in what mechanism it expands its poetic circumference. “Among School Children” is the very poem his poetic self and creative imagination are well wrought into. In the poem, the poet suggests that power and knowledge cannot exist together, speaking of the powerful theories of Plato and simultaneously of the philosopher’s powerless being before Nature. He praises Aristotle as a king of kings, and Pythagoras as world-famous golden-thighed, but he mocks them of being old clothes upon an old stick to scare a bird. In the same way, he asserts that “the body is not bruised to pleasure soul.” In the sense of deconstructionists, all the binary oppositions have their hierarchies; however, Yeats puts the two antithetical elements on the identical level, as they are not subordinated to each other, and tries to bridge the abyss or space between. Such an attempt to unite the opposite worlds is manifested in his A Vision. Concerning his “gyre” theory, the figure is frequently drawn as a double cone. The one is called primary gyre, representing space, intellect, mask and fortune; the other antithetical one to represent time, emotion, creativity and will. The narrow end of each cone is in the centre of the broad end of the other. Seen at the narrow end of each cone through the centre of each broad end, appears a circle having a dot at the center. This is the poet’s world of imagination whose centre is his “self” and whose circumference is the limit of the self’s perception. The poet’s life-long activities are related with his efforts to expand the circumference. “Among School Children” is a trace of such activities. The centre is the place where the self of the poet is located; the circumference is where the self “perceives its limitation,” or where arises the feeling of awe, terror, or ecstasy, which means a kind of tension geared between the binary opposite worlds: the finite and the infinite; the mortal and the immortal; life and death; the real and the ideal; youth and age; the body and soul; pleasure and despair. The perception network of the poet connects the centre and circumference. The power to widen the circle originates from the poet’s paradoxical sense of life, of deprivation, and of renunciation through an attainable love with Maud Gonne, tensions between religious struggles, civil revolutions, and so on. The sharp confrontation of these tensions takes place rise to in the circumference and stimulates the poet’s creative imagination. This power of self strengthened by these tensions starts its quest-journey to explore the mysteries beyond the limit of its circle: the mysteries of the opposite worlds separated here and there. The ultimate purpose of the journey, finally, is to reach the united condition of the two worlds, which means what Greg Johnson calls “the highest imaginative enhancement of human identity” or immortality. This united world is the place where “we cannot know the dancer from the dance” and where Yeats’s “unity of being” is synthesized.

국립 경남과학기술대학교 공학교육혁신센터: 미래산업혁신을 선도할 창의융합형 공학인재양성 선도센터

유석형 한국공학교육학회 2019 Ingenium(人材니움) Vol.26 No.3

W. B. 예이츠의 시세계에 나타난 상징과 원효사상 비교연구

유석형 한국예이츠학회 2003 한국예이츠 저널 Vol.20 No.-

The focus of study in this paper is put on the comparison of symbolism manifested in the world of W. B. Yeats’ poetry and the thoughts of Master Won-hyo.. The comparing works include the identification of their understanding ways of life. The symbols in common to bridge W. B. Yeats and Master Won-hyo are, for instance, circle, cone, cycle, sphere, spiral, wheel, vehicle, etc. Such a sign symbolizes a round thing, in another expression, the world or the cosmos where man belongs to. The phenomenological world or the cosmos by oriental thoughts is represented as the 28 phases of the moon, ranging from the dark moon(objectivity) to the full moon(subjectivity), which according to W. B. Yeats’ theory are identified the same kinds of character of man. Won-hyo(元曉, 617~686), a life-long friend of another Buddhist Master Ui-sang., insisted on the necessity for every living being to return to the foundation of the One Mind(一心), which is the original state of being, in another words, or “Ultimate Reality” to which every living being has to return. The Hwa-yen Sutra(華嚴經), a rare scripture of Mahayana Buddhism(大乘佛敎), emphasizes that the Ultimate Reality is the Source of One Mind of Won-hyo. We can say that Mahayana Buddhism teaches every living being the way to return to the world of the Ultimate Reality by great vehicle of Mahayana(大乘) in sanskrit. Another principle of Hwa-yen philosophy may be expressed as All in one, one in all. One is all, all is one(一中一切一切中一, 一卽一切一切卽一). The Six Aspects(六相) is interpretated by the principle. The mutual relationships are harmonized between the whole and a part, between the unity of the whole and the diversity of the part, and between the completion of the whole and the self-denial of the part. The One Mind is synonymous with the Great Vehicle with great wheels, which return to the Source of One Mind, the original state of being, or the Ultimate Reality( or Nirvana). The meaning of the One Mind may be expanded to the synonym of the existential world or the cosmos, at the center of which the One Mind lies. Accordingly, The One Mind, the Great Vehicle or Great Wheel and the World has a similar analogy, which make a system of symbolism, so called “Yeatsian gyre theory.” Yeats imagined a spiral, which he preferred to call a gyre) or whirling cone. Then two such cones were drawn and considered to pass like the human soul through a cycle from subjectivity to objectivity. These cones were imagined as interpenetrating, whirling around inside one another, one subjective, the other objective. The cones were not restricted to symbolizing objectivity and subjectivity. They were beauty and truth, value and fact, particular and universal, quality and quantity, abstract and concrete, and the living and the dead. Yeats thought that he had discovered in the figure of interpenetrating gyres the archetypal pattern which is mirrored and remirrored by all life, by all movements of civilization or mind or nature. Man or movement is conceived of as moving from left to right and then from right to left. No sooner is the fullest expansion of the objective cone reached than the counter-movement towards the fullest expansion of the subjective cone begins. These movements slide to the 28 phases of the moon. The dark moon, in the course of wane and wax sways to the full moon. The different 28 patterns of the moon is mirrored by all life or mind, ranging from the highest state of subjective mind(the 15th phase: the full moon) to the highest cast of objective mind(the 1st phase; the dark moon). In the long run, the world which Won-hyo and Yeats seek for as an ideal space of mind is a unified one, into which melted are the binominal opposites such as objectivity and subjectivity, the sacred and the profane, the bishop and Jane, fair and foul, the dancer and the dance, beauty and truth, value and fact, particular and universal, quality and quantity, abstract and concrete, and the living and the dead.

동적응답신호를 이용한 건축물의 손상추정기법

유석형 한국구조물진단유지관리학회 2013 한국구조물진단유지관리공학회지 Vol.17 No.4

경골목구조 벽체의 내화성능확보를 위한 질석보드 개발

유석형,정창헌 한국화재소방학회 2018 한국화재소방학회논문지 Vol.32 No.1

무기재로서 질석은 친환경적인 특성과 내화, 단열, 흡음 뿐 만 아니라 결로방지, 탈취 및 미관 등이 우수하므로건축마감재로서 활용될 경우 효용성이 높을 것으로 판단된다. 본 연구에서는 질석을 주원료로 하여 미네랄 루즈울(Mineral Loose Wool) 또는 미네랄 파우더(Mineral Powder)를 혼입한 건축용 마감보드를 개발하고 불연시험과 단열시험을 수행하였다. 시험결과 두 개의 질석보드 모두 불연재로서 성능을 확보하였으며 열전도율 0.086 및 0.092 W/m⋅K로 나타났다. 또한 개발된 두 개의 질석보드를 경골목구조 내화벽체 표준상세(KS F 1611-1)의 마감재로 적용하여내화시험을 수행하였다. 내화시험결과 VB-L 시험체가 VB-P시험체 보다 내화성능이 다소 높게 나타났으며 두 개의질석보드 모두 두께 30 mm로도 내화성능 2시간 확보가 충분한 것으로 나타났다. It is considered that vermiculite as an inorganic material is highly effective when it is used as a building finishing materialbecause it is eco-friendly. Vermiculite has excellent properties such as fire resistance, heat insulation, sound absorption as wellas prevention of condensation, deodorization and aesthetics. In this study, we developed a finishing board with vermiculiteas its main material and mixed with mineral loose wool (VB-L) or mineral powder (VB-P), and conducted fireproof test andinsulation test. In addition, fire resistance tests were carried out by applying the two developed vermiculite boards as finishingmaterials for the standard wall details of light frame wood structures (KS F 1611-1). As a result of the fire resistance test,the VB-L specimen showed better fire resistance than the VB-P specimen. Both vermiculite boards showed sufficient fireresistance performance of 2 hours for a thickness of 30 mm.

철골 끼움가새골조로 보강된 학교건물의 내진성능평가를 위한 비선형 해석 모델에 관한 연구

유석형,고관욱 한국구조물진단유지관리공학회 2022 한국구조물진단유지관리공학회 논문집 Vol.26 No.4

Recently, damage to buildings due to earthquakes in Korea occurred mainly in school buildings and Piloti-type multi-family houses, highlighting the need for seismic retrofit for buildings of the same type. In the early days of the seismic retrofit project for school facilities, various patented methods using dampers as a ductile seismic retrofit method were applied without sufficient verification procedures. However, in 「 School Facility Seismic Performance Evaluation and Retrofit Manual, 2021」, when the patented method is applied, it must be applied through a separate strict verification procedure, and instead, the strength/stiffness retrofit method was induced as a general method. In practice,when evaluating seismic performance for retrofit by infilled steel frame with brace, the analysis model is constructed by directly connecting only the steel brace to the existing RC member. However, if the frame is removed from the analysis model of the infilled steel frame with brace, the force reduction occurring on the existing RC member near the retrofit is considered to be very large, and this is judged to affect the review of whether to retrofit the foundation or not. Therefore, in this study, preliminary analysis with variables such as whether or not steel frame is taken into account and frame link method for the analysis model of RC school building retrofitted by infilled steel frame with brace and nonlinear analysis for actual 3-story school building was performed, and basic data for rational analysis model setting were presented by comparing preliminary analysis and pushover analysis results for each variable. 최근 국내 지진으로 인한 건축물의 피해는 주로 학교건물과 필로티형 다가구 주택에서 발생함으로써 동일한 형식의 건물에 대한 내진보강 필요성을 부각시켰다. 학교시설 내진보강사업은 초기에 연성보강방법으로서 댐퍼를 활용한 다양한 특허공법들이 충분한 검증 절차 없이 적용되었다. 그러나 「학교시설 내진성능평가 및 보강 매뉴얼, 2021」에서는 특허공법 적용시 별도의 엄격한 검증절차를 통하여 적용토록 하고 대신 일반공법으로서 강도/강성보강공법의 활성화를 유도하였다. 학교건물의 강도/강성 보강공법으로서 활발히 적용되고 있는 철골 끼움가새골조보강을 위한 내진선능평가 시 실무에서는 일부 제한된 조건에서 안전측의 내진성능평가 결과를 도출할 것으로 판단하여 기존 RC부재에 철골가새만을 직접연결하여 해석모델을 구성하고 있다. 그러나 철골 끼움가새골조의 해석모델에서 프레임을 제거할 경우 강성감소로 인한 보강 부근의 기존 RC부재에 발생하는 하중감소는 매우 클 것으로 사료되며 이는 보강부위 기초보강 유무 검토에도 영향을 미칠 것으로 판단된다. 따라서 본 연구에서는 철골 끼움가새골조를 이용하여 저층 RC 학교건물 내진보강 시 성능평가를 위한 해석모델에 대하여 철골 프레임 고려 유무, 프레임 링크방식 등을 변수로 한 예비해석과 실제 3층 학교 건물에 대한 비선형 정적해석에 따른 내진성능평가 를 수행하였으며, 변수별 예비해석 및 푸쉬오버 해석결과를 비교함으로써 합리적인 해석모델 설정을 위한 기초자료를 제시하였다.

大陸橫斷鐵道와 歐洲 定期船社間의 運送競爭力 比較

柳奭馨 韓國海洋水産開發院 1992 (월간) 해양수산 Vol.- No.98

豫想된 通貨의 實物經濟效果에 대한 實證分析

柳奭馨 연세대학교 산업경영연구소 1992 산업과경영 Vol.10 No.1

合理的 期待論者(rational expectationist)들 期待된 通貨(expected money) 또는 豫想된 通貨(anticipated money)는 實物生産에 영향을 주지 않는다고 주장한 이후 않은 경제학자들이 이 이론에 대해 비판을 하였다. 중요한 비판중 하나는 합리적 기대론자가 사용하고 있는 總供給兩數가 너무 단순하며, 총공급에 영향을 줄 수 있는 이자율, 자신, 또는 조세부담율 등의 중요한 요인들이 총공급함수에서 간과되어 있파는 것이다.

웨이블렛 변환을 이용한 건물의 손상추정을 위한 소형 진동대 실험

유석형,송진규 대한건축학회지회연합회 2012 대한건축학회지회연합회 학술발표대회논문집 Vol.2012 No.1