야생버섯에서 분리한 미기록종 버섯기생균 Sepedonium laevigatum 보고

오승윤 한국버섯학회 2022 한국버섯학회지 Vol.20 No.4

Fungi that infect mushrooms and cause diseases are called mycoparasitic fungi. Understanding the diversity of mycoparasitic fungi in wild mushrooms is important for the mushroom industry, as they can parasitize cultivated mushrooms. However, few studies have been conducted on the diversity of mycoparasitic fungi in wild mushrooms in South Korea. Upon surveying mushroom flora, we found a mycoparasitic fungus and analyzed its strain using molecular phylogeny and morphological examination. The strain was identified as Sepedonium laevigatum, which is an unrecorded species in South Korea. In this study, we described the cultural and microscopic characteristics of this strain of fungus.

동의수세보원(東醫壽世保元) 신정(新定) 처방(處方) 약재(藥材)의 약침 안전성 문헌 조사

오승윤,김구,권영미,이시우,장은수,주종천,Oh, Seung-Yun,Kim, Koo,Kwon, Young-Mi,Lee, Si-Woo,Jang, Eun-Su,Joo, Jong-Cheon 사상체질의학회 2011 사상체질의학회지 Vol.23 No.1

1. Objectives: Pharmacopuncture according to Sasang Constitutional Medicine is new field of constitutional medicine. We investigated safety of pharmacopunctures to develop this treatment. 2. Methods: We searched for papers in fifteen Korean oriental medical journals and four online searching portal articles. Hepatotoxicity, nephrotoxicity and general toxicity tests were investigated about one hundred thirty kinds of pharmacopunctures. 3. Results: Toxicity test about 36 kinds of 130 pharmacopunctures were investigated. 1) Hepatotoxicity and nephrotoxicity test of pharmacopunctures were searched in 11 of 38 Soeumin herbs, 8 of 36 Soyangin herbs, 5 of 44 Taeeumin herbs and 1 of 12 Taeyangin herbs. From among these herbs, toxicity was detected in Radix aconiti lateralis preparata(附子), Fructus alpiniae oxyphyllae(益智仁), Semen crotonis(巴豆), Radix bupleuri(柴胡) and Semen armeniacae amarum(杏仁) pharmacopunctures. 2) General toxicity test of pharmacopunctures were searched in 8 of 38 Soeumin herbs, 9 of 36 Soyangin herbs, 6 of 44 Taeeumin herbs and 2 of 12 Taeyangin herbs. from among thes herbs, toxicity was detected in Radix aconiti lateralis preparata(附子), Radix ginseng(人蔘), Semen crotonis(巴豆), Rhizoma seu radix notopterygii(羌活), Radix aralia cordatae(獨活), Semen armeniacae amarum(杏仁) and Radix scutellariae(黃芩) and Cortex acanthopanacis(五加皮) pharmacopunctures. 4. Conclusions: From these results, we must decide extraction method, concentration and dose carefully to use the toxic pharmacopuncture. More toxicity test and further study is needed about pharmacopuncture treatment in Sasang Constitutional Medicine.

원인불명 오심 구토의 태양인 미후등식장탕 치험1례

오승윤,박수정,박혜선 사상체질의학회 2023 사상체질의학회지 Vol.35 No.4

Objective To report the improvements with Mihudeungsikjang-tang on taeyangin patient with unexplained nausea and vomiting. Method The 55-year-old woman had severe nausea and vomiting after taking laxatives about 2 months ago. However, endoscopy and other examination findings were unremarkable except for gastritis. Soyangin Dojeokganggi-tang and taeyangin Mihudeungsikjang-tang were applied as a main treatment. Results The symptoms of nausea and vomiting were immediately improved after constipation disappeared applying Mihudeungsikjang-tang. Conclusion This case showed that Mihudeungsikjang-tang according to the appropriate constitutional diagnosis could improve nausea and vomiting which were not improved by other treatments.

Efficacy of Herbal Medicine as an Adjunctive Therapy of Chemotherapy for Cervical Cancer: A Systematic Review and Meta-analysis

오승윤,김미숙,주종천,송용선 한의병리학회 2020 동의생리병리학회지 Vol.34 No.5

This study aimed to evaluate the efficacy of herbal medicine (HM) combined with chemotherapy (CT) for cervical cancer. Ten electronic databases including Pubmed, Cochrane library, Embase, Korean databases, and Chinese medical databases were systematically searched up to October 2019. All randomized controlled trials with HM combined with CT to treat cervical cancer were included. A total of 21 trials were included for analysis. Compared to the control group, HM combined with CT group significantly increased tumor response (complete and partial response) (risk ratio [RR] = 1.24, 95% CI: 1.15–1.33, p < 0.00001) and Karnofsky performance score (standardized mean difference [SMD] = 1.71, 95% CI: 1.41–2.01, p < 0.00001). Also, HM combined with CT group remarkably reduced CT toxicity. In Conclusion, our study suggests that HM might be a potential option for cervical cancer to enhance curative efficacy and reduce CT toxicity.

데이터베이스 검색을 통한 종양의 사상체질의학 관련 연구 문헌 고찰

오승윤,Oh, Seung-Yun 사상체질의학회 2020 사상체질의학회지 Vol.32 No.3

Objectives The purpose of this review was to investigate constitutional medical research on tumors and to propose information for further research. Methods The literature was investigated from Oriental medicine advanced searching integrated system, China national knowledge infrastructure, and PubMed. The searching terms were cancer, tumor, neoplasm, Sasang constitution, and so on. And studies were collected and analyzed into the three parts of distributions, treatments, and preventions. Results The distribution and type of tumors were different depending on the type of Sasang constitution. The symptoms of a tumor can occur variously in all types of diseases or patterns. Preventing tumors and cultivating health should be considered all aspects of physical, mental, and social health in the Sasang constitutional concept of securing requisite energy of minor organs. Conclusions The Sasang constitutional medicine for treating tumors should be focused on strengthening the constitutional healthy energy considering personal characteristics.

족저근막염의 초음파유도하 봉약침 치험1례

오승윤,염지윤,박수정 대한한의학회 2023 대한한의학회지 Vol.44 No.1

Obje cti v e s: This study is to report the usefulness of ultrasound in diagnosing plantar fasciitis and the effectiveness of ultrasound-guided bee venom pharmacopuncture as a treatment of it. Methods: A 61-year-old woman suffered from plantar fasciitis on her right foot for 1 month. The sonographic findings were fascial thickening, blurring of perifascial border and perifascial effusion. The ultrasound-guided bee venom pharmacopuncture for 6 times and conventional Korean medicine therapies like acupuncture and moxibustion for 12 times in 5 weeks. Numeric rating scale (NRS) and foot function index(FFI) was used to evaluate the pain and its progress. and thickness of plantar fascia was measured by sonography every week. Results: After treatments, NRS and FFI were reduced from 10 to 1 and from 190 to 72. The thickness of fascia was reduced from 0.43cm to 0.40. Blurring and effusion of perifascial border were also improved. Conclusion: This report suggests that the Ultrasound-guided Bee Venom Pharmacopuncture is effective for Plantar Fasciitis. Ultrasonography could be one of the most valuable items in the clinical practice of Korean medicine doctors who seek minimally invasive treatment.

국내 데이터베이스 검색을 통한 암성통증의 약침치료 임상연구 동향

오승윤,신뢰,주종천,박수정,Oh, Seung-Yun,Shen, Lei,Joo, Jong-Cheon,Park, Soo-Jung 대한암한의학회 2020 大韓癌韓醫學會誌 Vol.25 No.2

Objectives: The effectiveness of acupuncture on cancer pain is relatively well established, while there have been few clinical studies on pharmacopuncture on that. This research was aimed to investigate a trend of pharmacopuncture treatment for cancer pain and to propose information for further research. Methods: Clinical studies on pharmacopuncture for cancer pain were collected from 5 Korean medical databases. And the studies were analyzed by classifications of cancer, chief complaints, interventions, treating skills, additional treatments, treatment session, outcome measures, results and adverse effects. Results: The literatures were 8 case reports and 1 randomized controlled trial. Interventions were pharmacopunctures of soyeom, mountain ginseng, Harpagophyti Radix, snake venom, Trionycis Carapax, bee venom, Aconitum Ciliare Decaisne. Treatment skills, procedures, and indications of each pharmacopuncture were different. An adverse effects of bruising, bleeding, mild chilling, sore throat and pain were mentioned on snake venom and bee venom treatment. Conclusions: An appropriate interventions and treatment skills should be selected according to the type of cancer pain. And treatment procedures to ensure safety must be developed.

흡입화상으로 유발된 만성 기관지염의 태음인 마황정천탕(麻黃定喘湯) 치험 1례

오승윤,곽시라,Oh, Seung-Yun,Gwak, Si-Ra 사상체질의학회 2020 사상체질의학회지 Vol.32 No.3

Objectives To report an improved case with Taeeumin Mahwangjeongcheon-tang on the patient with chronic bronchitis caused by an inhalation injury. Methods The patient had been suffered from cough, sputum, dyspnea, and chest discomfort for 15 years. He was diagnosed as Taeeumin Esophageal Cold Pattern and was given Mahwangjeongcheon-tang according to Sasang constitutional medical theory. The clinical asthma measurement scale in oriental medicine(CAMSOM-V), quality of life questionnaire for adult Korean asthmatics(QLQAKA), and Spirometry were performed to evaluate the improvement of his symptoms. Results The clinical asthma measurement scale in oriental medicine(CAMSOM-V) improved from 16 to 14 points and the quality of life questionnaire for adult Korean asthmatics(QLQAKA) improved from 55 to 67 points. In spirometry, forced vital capacity improved from 3.07 to 3.59, and forced expiratory volume in 1sec improved from 2.59 to 2.84 after 4 weeks. Conclusion This report suggests that Mahwangjeongcheon-tang is effective for chronic bronchitis.

외측상과염의 초음파유도하 자하거약침 치험1례

오승윤,김명호,박수정 대한한의학회 2024 대한한의학회지 Vol.45 No.2

Objectives: This case study aims to demonstrate the efficacy of ultrasound-guided hominis placenta pharmacopuncture in lateral epicondylitis. Methods: A 42-year-old male patient presented with lateral epicondylitis of the right arm of 4 months’ duration. Sonographic findings were tearing of the common extensor tendon at the lateral epicondyle. The patient was treated with ultrasound-guided hominis placenta pharmacopuncture and acupuncture for 9 weeks. The numeric rating scale (NRS) and patient-rated tennis elbow evaluation(PRTEE) were used to assess pain, function and progression. Ultrasound images were compared every 2 weeks. Results: After treatments, NRS and PRTEE were reduced from 7 to 1 and from 106 to 22, respectively. And improvement was observed in the torn region of the common extensor tendon on ultrasound imaging. Conclusion: This case demonstrates that ultrasound-guided hominis placenta pharmacopuncture could improve lateral epicondylitis and tear with minimally invasive methods.

사상체질별 관격(關格)치료 약물인 파두(巴豆), 감수(甘遂), 과신(瓜莘)의 문헌 고찰

오승윤,이시우,주종천,Oh, Seung-Yun,Lee, Si-Woo,Joo, Jong-Cheon 사상체질의학회 2008 사상체질의학회지 Vol.20 No.2

1. Objectives I investigated the effects and mechanisms of Semen Tiglii(ST, 巴豆), Radix Euphorbiae Kansui(REK, 甘遂) and Pedicelus Melo(PM, 瓜莘) in the view of Sasang Constitutional Medicine. 2. Methods I analyzed the literature about oriental medicine and Sasang Constitutional medicine related to herbal Medicine. The contents analyzed were efficacious disease, dosage, usage, side effect, toxicity. 3. Results The first, similarities of ST, REK and PM are improving Gwangyuk, the Chest Discomfort with Constipation, Dysuria and Nausea, toxic, used in urgency, asministered by itself and used shaped powder. The second, ST and REK used the diseases related water and food metabolism in Soumin and Soyangin. PM used the diseases related Qi and fluid metabolism in Taeumin. The third, diarrhea caused by ST and REK is symptom to retrieve the diseases related water and food metabolism. The vomiting caused by PM is symptom to retrieve the diseases related Qi and fluid metabolism. 4. Conclusions The ST, REK and PM is good herbal medicine (() retrieve the urgency symptom caused by the body unbalance in Sasang Constitutional Medicine. The proper dosage is essential because of toxicity of drugs.