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정지인(Ji Inn Jung),손석호(Suk Ho Sohn),조욱현(Wook Hyun Cho),정정희(Jung Hee Jung),김용림(Yong Lim Kim),이진관(Jin Kwan Lee) 대한내과학회 1993 대한내과학회지 Vol.45 No.3
N/A Background: The prevalence of antibody to hepatitis C virus (anti-HCV) in healthy subjects from Korean has been investigated in various studies. But most of these studies were estimated from data in blood donors who were mostly young adults. So these studies could not represent the prevalence of anti-HCU in all age groups and its age distribution. Method: The prevalence of anti-HCV among healthy subjects in Ulsan area was evaluated using commercially available enzyme immunoassay. We studied a correlation between anti-HCV and alanine aminotransferase (ALT) level, and between anti-HCV and HBs Ag. Effects of increasing age and blood transfusion were also evaluated. Results: 1) The overall prevalence of anti-HCV was 1.079 among 3,000 healty subjects. 2) Male to female ratio was 2.5:1. The prevalence of anti-HCV among male subjects (1.21%) was higher than that among female subjects (0.7%). 3) Anti-HCV prevalence increased with increasing age through the fourth decade of life. 4) There was no significant difference both in the prevalence of anti-HCV in healthy subjects with or without HBs Ag and in the prevalence of anti-HCV in healthy subjects with or without the history of transfusion. 5) Anti-HCV prevalence increased linearly with the increase of alanine aminotransferase level. Conclusion: The prevalence of anti-HCV in healthy subjects in Ulsan area was 1.07%. There was a significant increase with increasing age above 30 years. There was a good correlation between the prevalence of anti- HCV and ALT level, but the prevalence of anti-HCV was not associated with blood transfusion.
종합검진상 발견된 C형 간염 항체 양성자의 추적과 HCV RNA 검출율
이진관(Jin Kwan Lee),김정철(Jung Chul Kim),정정희(Jung Hee Jung),이창구(Chang Goo lee),최형경(Hyeong Kyoeng Choi),손석호(Suk Ho Sohn),조욱현(Wook Hyun Cho),허충(Chung Hur) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.6
N/A Follow up study and HCV RNA test by PCR was performed on the 26 asymptomatic subjects with anti-HCV found in routine health check. Among the 26 sugjects, 16 have persistently normal ALT level and 10 abnormal ALT level. In 6 subjects, anti-HCV turned to be negative on follow up test and among those, 5 have normal ALT level and one abnormal ALT level. 15 subjects with normal ALT level have HCV RNA and those subjects were assumed to be asymptomatic hepatitis C carrier. HCV RNA was positive in 8 out of 10 subjects with abnormal ALT level. In conclusion, 23 out of 26 asymptomatic subjects with anti-HCV have HCV-RNA and among them 15 with normal ALT level were assumed to be asymptomatic hepatitis C carrier.
성인에서 발견된 Prune-belly Syndrome 1 예
김종수,이병화,김용림,이진관,손석호,조욱현 대한내과학회 1995 대한내과학회지 Vol.48 No.1
A 28-year-old man was diagnosed as having prune-belly syndrome, a congenital disease characterized by abdominal wall defects, undescended testes, a generalized dilatation of the urinary tract, and chronic renal failure. The patient also demonstrated metatarsus varus and pectus excavatum. The patient was asymptomatic until the diagnosis was made at the age of 28 years. This is the first case report of prune-belly syndrome in adulthood in Korea.