실란을 포함한 친수성 콘택트렌즈의 물리적 특성에 대한 Isocyanate Group의 영향

성아영,조선아,김태훈,Sung, A-Young,Cho, Seon-Ahr,Kim, Tae-Hun 대한화학회 2012 대한화학회지 Vol.56 No.5

본 연구는 triacetoxyvinlysilane을 첨가제로 사용하여 교차결합제인 EGDMA (ethylene glycol dimethacrylate)와 HEMA (2-hydroxyethyl methacrylate), MMA (methyl methacrylate), MA (methacrylic acid) 그리고 개시제인 AIBN (azobisisobutyronitrile)과 함께 공중합 하였다. 생성된 고분자의 물리적 특성을 측정한 결과, 함수율 35.63~32.44%, 굴절률 1.4382~1.4480, 가시광선 투과율 89.0~92.5%, 인장강도는 0.346~0.674 kgf를 나타내었다. 기본 모노머 조합에 triacetoxyvinlysilane을 첨가한 조합과 1%의 hexamethylene diisocyanate를 첨가하여 중합한 조합의 물성을 비교한 결과 hexamethylene diisocyanate 1%를 첨가하여 중합한 렌즈의 인장강도가 더 큰 값을 나타내었다. 본 실험결과로 볼 때 생성된 공중합체는 내구성 및 인장강도가 우수한 안의료용 렌즈 재료로 사용될 수 있을 것으로 판단된다. The copolymerization of triacetoxyvinylsilane, EGDMA (ethylene glycol dimethacrylate as a cross-linker), HEMA (2-hydroxyethyl methacrylate), MMA (methyl methacrylate), MA (methacrylic acid) was performed in the presence of AIBN (2,2'-azobisisobutyronitrile) as an initiator. Measurement of the physical properties of the resulting copolymers showed that water content, refractive index, visible ray transmittance, and tensile strength were in the range of 35.63~32.44%, 1.4382~1.4480, 89.0~92.5% and 0.346~0.674 kgf, respectively. The values of tensile strength of copolymers-containing hexamethylene diisocyanate were higher than those of the copolymers containing triacetoxyvinylsilane. From the results we came to the conclusion that the produced copolymers are suitable for the application of ophthalmic contact lens with high tensile strength, wettability and duraility.

POLYMERIZATION OF HEMA IN THE PRESENCE OF PHENYLSILANES

성아영,Sung, A-Young 한국안광학회 2001 한국안광학회지 Vol.6 No.2

Phenylsilane들과 2-Hydroxyethylmethacrylate(HEMA)의 광중합은 말단기에 phenylsilyl기를 포함하고 있는 poly(HEMA)s를 생성시킴으로써 열중합과 같은 결과를 보였다. 중합반응 동안에 실란의 몰비율이 증가함에 따라 중합수율과 고유점도는 감소하였으며, TGA 잔여수율과 Si-H IR 신축띠의 상대적 세기는 증가하는 경향을 보였다. phenylsilanne은 HEMA와의 광중합 반응에서 연쇄개시제와 전달물질로 중요한 영향을 주었다. The bulk photopolymerization of 2-hydrxyethylmethacrylate(HDMA) with phenylsilane was perforemed to produce poly(HEMA)s containing phenylsilyl moiety presumably as an end group. This result, are the same as that of thermal polymerization. It was found that while the polymerization yields and intrinsic viscosities decreased, the TGA residue yields and the relative intensities of SiH IR stretching bands increased with increasing molar ratio of phenylsilane over HEMA. The phenylsilane seemed to significantly influence on the photopolymerization as both chain initiation and chain transfer agents.

THERMAL POLYMERIZATION OF 2-HYDROXYETHYL METHACRYLATE WITH PHENYLSILANS

성아영,Sung, A Young 한국안광학회 2000 한국안광학회지 Vol.5 No.2

Poly(HEMA)는 소프트 콘택트렌즈의 재료로써 널리 사용되어 왔다. $phSiH_3$, $phMeSiH_2$, $ph2SiH_2$와 같은 다양한 hydrosilane들과 hydroxyethyl methacrylate(HEMA)와의 열중합은 Phenylsilyl 말단기를 포함하는 poly(HEMA)를 생성시켰다. 열중합 반응 동안에는 Phenylsilane의 농도가 증가함에 따라 고분자의 분자량과 고분자 수득률이 감소됨을 보였으며 광중합 반응에서 보다 중합 수득률, 고분자의 분자량, TGA 잔여 수율 등이 더 높았다. Poly(HEMA)s have been used as the optometric material for the preparation of soft contact lens. The bulk thermal polymerization of 2-hydroxyethyl methacrylate (HEMA) with various hydrosilanes such as $phSiH_3$, $phMeSiH_2$, and $ph2SiH_2$ were performed to produce poly(HEMA)s containing phenylsilyl end moeity. It was found for thermal polymerization that while the polymerization yield and polymer molcular weights decreased as the relative phenylsilane concentration increases, the TGA residue yields and the relative intensities of SiH IR stretching bands increased as the relative hydrosilane concentration increases over HEMA. The polymerization yield, molecular weight, and TGA residue for the thermal polymerization were higher than those for the photo polymerization. Thus, the hydrosilanes significantly influence on the polymerization as both chain-initiation and chain-transfer agents.

UV Absorbent-added Polymerization and its Application as Ophthalmological Material

성아영,김태훈,예기훈,Sung, A-Young,Kim, Tae-Hun,Ye, Ki-Hun Korean Chemical Society 2011 대한화학회지 Vol.55 No.1

본 연구는 자외선 흡수제로 사용되는 benzophenone계(group) 및 높은 굴절률과 화학적, 물리적으로 매우 안정한 물질로 알려진 $TiO_2$를 기존의 재료에 첨가하여 자외선 차단 기능을 가진 고분자 재료를 중합하였다. 중합 결과 생성된 고분자의 자외선 흡수 정도를 기존의 재료들과 비교하였으며, 제조된 콘택트렌즈의 함수율, 굴절률 및 광투과율등의 기본적인 물성을 측정하였다. 측정 결과, 자외선 흡수제를 첨가한 콘택트렌즈의 굴절률과 함수율은 각각 1.430~1.440, 35.0~45.0의 값들로 나타나 기존의 콘택트렌즈와 비슷한 결과를 나타내었다. 또한 각 파장대별 광투과율에서는 자외선 흡수제를 넣지 않은 콘택트렌즈에서는 UV-A, UV-B, 가시광선 투과율이 각각 89%, 88%, 89%로 나타나 자외선 투과율이 매우 높았으나, 2-hydroxy-4-methoxy-benzophenone와 2,4-dihydroxy-benzophenone을 첨가한 콘택트렌즈의 경우, 각각 UV-A 0%, UV-B 6%의 투과율을 나타내어 자외선 차단 효과가 있는 것으로 나타났다. 또한 $TiO_2$를 첨가한 콘택트렌즈의 경우, 각각 UV-A 6%, UV-B 51%의 투과율을 나타내어 자외선 차단 효과가 다소 있는 것으로 나타났다. 가시광선 투과율은 모두 77~89%로 콘택트렌즈의 가시광선 투과율의 조건에 만족함을 알 수 있었다. This study was done for the preparation of macromolecular material with UV-blocking features by adding the benzophenone group that is commonly used as a UV-absorbent and $TiO_2$ which is known to be a very stable material in chemical and physical aspects. Also, we compared the level of UV absorbency of the polymer produced from polymerization with previous materials and measured basic properties such as water content, refractive index and optical transmittance of produced contact lenses. The results of the measurement showed that the refractive index and water content of the contact lens with added UV-absorbent was 1.430~1.440 and 35.0~45.0% respectively, which was similar to that of previous contact lenses. Also, for optical transmittances of each wave length, contact lenses without the UV-absorbent was 89%, 88% and 89% respectively for UV-A, UV-B and visible light, indicating that the UV transmittance is very high though contrary with cases of contact lenses with added 2-hydroxy-4-methoxy-benzophenone and 2,4-dihydroxy-benzophenone which showed transmittances of 0% and 6% respectively for UV-A and UV-B showing a UV-blocking effect. Meanwhile, contact lenses with added $TiO_2$ showed transmittance of 6% and 51% respectively for UV-A and UV-B also showing a UV-blocking effect. The visible transmittance was 77~89% showing that it satisfies the visible transmittance required for ophthalmological materials.

각막굴절수술(라식) 환자에 대한 경향성 분석

성아영,김찬수,이석주,조수현 대불대학교 2002 論文集 Vol.8 No.1

Now a days, LASIK(laser in situ keratomileusis) surgical operation is enforced widely by method that is used to correct ametropia such as near-sightedness, far-sightedness, astigmatism etc. This wishes to solve troublesome matter for glasses and contact lens wearer that reform a part of corneal stroma by laser after using microkeratome in which make corneal flap. This experiment present that refraction by auto-refractometer in point of time before and after a week to those who undergone LASIK surgical operation 30 patients. 60 eyes that become full corrected(spherical power : +0.50D∼-0.50D). By this research method, in point of time that examination has a week after operation because of refraction power changed by passage of time and classified by sex, age, occupation, and degree of myopia(low:-1.0D∼-3.0D, moderate: -3.0D∼-6.0D, high :more than -6.0D). As a result of this study LASIK surgery can solve uncomfortableness by wearing glasses or contact lens, but the result objectively doesn't meet satisfaction level though full correction had made.

바닥상태 및 들뜬상태에서 날리딕산 수용액의 해리에 관한 연구

성아영,이형철 대불대학교 1999 論文集 Vol.5 No.1

The ionization structure and ionization constant of nalidixic acid have been studied in the ground-and excited states at room temperature. The nalidixic acid has two chromophore in aqueous solution and the hydrogen atom combined in the carboxyl group of the molecule was dissociated in the aqueous solution. The ionization constant of nalidixic acid in the ground state was determined by spectrophotometric method and by potentiometric titration method. The pKa value of the substance was found to be 6.35 in aqueous solution. In the excited state, it was found to be 1.75. This result indicates that dipole moment of the molecule increased in the excited state very much rather than in the ground state.

콘텍트렌즈 착용전후 측정기기별 굴절력에 관한 연구

성아영,이종헌,박상철,김상균,송경석 대불대학교 2002 論文集 Vol.8 No.1

Heine's Retinoscope is 100% dust proof and incorporates a unique Integrated Polarizing filter which eliminates all internal glare, providing for a clearer, brighter papillary reflex, enhancing performance and ease of examination, As a result of their data basis, we observed and analyzed which instrument has lesser occurring refracting aberration. Contact lens Wearers assuming best visual acuity lead 1.0(20/20) performed over refraction using Retinoscope. Auto Refractor, Auto Refrac-Keratometer and Suresight. The Auto refractor provides highly accurate measurement of patients refraction error. Auto Refrac-Keratometer provides precise and efficient refraction and Keratometry measurements and suggests contact lens base curve values. The automatic calculation of residual astigmatism assists in fitting RGP lenses. Also, suresight is a most convenient instrument for refraction. 30 contact lens wearers are chosen regardless of age, sex, and job. At least 30 minute after placing contact lens in each subjects eye, Performing over refraction by use of Retinoscope, Auto refractor, Auto refrac-Keratometer and suresight. Then presenting each results by graph in consist of spherical part, cylinder, axis, left eye and right eye separately.

메타올-암모니아 혼합용액의 광반응에 미치는 산소의 영향에 관한 연구

성아영,이형철,김희정 대불대학교 1999 論文集 Vol.5 No.1

The photochemical reaction of ammonia in aqueous methanol have been investigated by using 184.9 nm UV light at 25 ℃. During the photochemical reaction of methanol-ammonia mixture solution (mole fraction = 0.10 : 5×10-4), carbonyl compounds such as formaldehyde, ethyleneglycol and glyoxal, and amine compounds such as methoxyamine, 1,1-dimethlyhydrazine and dimethylamine were produced along with minor products such as ethlyenediamine and hydrazine. The presence of oxygen affected to the photochemical reactions. The reaction probability of hydrogen radicals with both methanol and ammonia decreased in the presence of oxygen because hydrogen radicals reacted with oxygen in the air atmosphere, resulting in the decrease of Initial quantum yield.

UV Absorbent-added Polymerization and its Application as Ophthalmological Material

성아영(Sung, A-Young),김태훈(Kim, Tae-Hun),예기훈(Ye, Ki-Hun) 대한화학회 2011 대한화학회지 Vol.55 No.1

본 연구는 자외선 흡수제로 사용되는 benzophenone계(group) 및 높은 굴절률과 화학적, 물리적으로 매우 안정한 물질로 알려진 를 기존의 재료에 첨가하여 자외선 차단 기능을 가진 고분자 재료를 중합하였다. 중합 결과 생성된 고분자의 자외선 흡수 정도를 기존의 재료들과 비교하였으며, 제조된 콘택트렌즈의 함수율, 굴절률 및 광투과율등의 기본적인 물성을 측정하였다. 측정 결과, 자외선 흡수제를 첨가한 콘택트렌즈의 굴절률과 함수율은 각각 1.430~1.440, 35.0~45.0의 값들로 나타나 기존의 콘택트렌즈와 비슷한 결과를 나타내었다. 또한 각 파장대별 광투과율에서는 자외선 흡수제를 넣지 않은 콘택트렌즈에서는 UV-A, UV-B, 가시광선 투과율이 각각 89%, 88%, 89%로 나타나 자외선 투과율이 매우 높았으나, 2-hydroxy-4-methoxy-benzophenone와 2,4-dihydroxy-benzophenone을 첨가한 콘택트렌즈의 경우, 각각 UV-A 0%, UV-B 6%의 투과율을 나타내어 자외선 차단 효과가 있는 것으로 나타났다. 또한 를 첨가한 콘택트렌즈의 경우, 각각 UV-A 6%, UV-B 51%의 투과율을 나타내어 자외선 차단 효과가 다소 있는 것으로 나타났다. 가시광선 투과율은 모두 77~89%로 콘택트렌즈의 가시광선 투과율의 조건에 만족함을 알 수 있었다. This study was done for the preparation of macromolecular material with UV-blocking features by adding the benzophenone group that is commonly used as a UV-absorbent and which is known to be a very stable material in chemical and physical aspects. Also, we compared the level of UV absorbency of the polymer produced from polymerization with previous materials and measured basic properties such as water content, refractive index and optical transmittance of produced contact lenses. The results of the measurement showed that the refractive index and water content of the contact lens with added UV-absorbent was 1.430~1.440 and 35.0~45.0% respectively, which was similar to that of previous contact lenses. Also, for optical transmittances of each wave length, contact lenses without the UV-absorbent was 89%, 88% and 89% respectively for UV-A, UV-B and visible light, indicating that the UV transmittance is very high though contrary with cases of contact lenses with added 2-hydroxy-4-methoxy-benzophenone and 2,4-dihydroxy-benzophenone which showed transmittances of 0% and 6% respectively for UV-A and UV-B showing a UV-blocking effect. Meanwhile, contact lenses with added showed transmittance of 6% and 51% respectively for UV-A and UV-B also showing a UV-blocking effect. The visible transmittance was 77~89% showing that it satisfies the visible transmittance required for ophthalmological materials.

소프트웨어 관점에서 본 내장형 시스템의 테스트 프로세스

성아영(Ahyoung Sung),최병주(Byoungju Choi),최진영(Jinyoung Choi),이나영(Nayoung Lee),이장수(Jangsoo Lee) 한국정보과학회 2003 한국정보과학회 학술발표논문집 Vol.30 No.2Ⅱ

내장형 시스템의 기능이 복잡해지면서, 내장형 소프트웨어에 대한 테스팅이 중요하게 인식되고 있다. 특히 원자력 발전소 계통 기기와 같이 안전에 대한 치명도가 높은 Safety-Critical Embedded System일수록 탑재되는 내장형 소프트웨어에 대한 철저한 테스팅이 요구되기 때문에 본 논문에서는 대상 시스템에 탑재되는 소프트웨어 테스트를 중심으로 하여 Safety-Critical Embedded System을 위한 테스트 프로세스 및 이에 필요한 테스팅 기법을 제안한다.