주제와 관련된 토의자의 의견 - 한국인의 건강체중 기준산정을 위한 향후 연구 방향 제시 -

배종면 대한지역사회영양학회 2001 대한지역사회영양학회지 Vol.6 No.3

비교효과평가를 위한 성과연구

배종면 대한고혈압학회 2012 Clinical Hypertension Vol.18 No.1

In spite of being several results of efficacy obtained by randomized controlled trials about new health technologies, evidences related to real effectiveness confirmed by head-to-head direct comparison should be needed in order to improve qualities of healthcare. The comparative effectiveness evaluation (CEE) as outcomes research have suggested as the important tool for developing evidence-based information to patients, clinicians, and other decision makers about which technologies are most effective for which patients under specific circumstances. Four major methods of outcomes research are applied as systematic reviews and meta-analyses, cohort studies using registries, linkage of large databases, and pragmatic clinical trials. Through activating the CEE, the best and most effective technologies should be adopted rapidly in routine clinical practices.

제주도 암발생 양상에 관한 가설 제기 및 규명

배종면,Bae, Jong-Myon 대한예방의학회 2009 예방의학회지 Vol.42 No.1

Objectives : Using the population-based cancer registry in Jejudo, we found that Jejudo had lower incidence in stomach cancer than other regions in Korea. The aim of this study was to evaluate reasons for this difference. Methods : Citrus is the leading agricultural production in Jejudo, suggesting that lower cancer incidence in Jejudo could be explained by citrus fruit intake. We evaluated this hypothesis with quantitative systematic review(QSR). Results : Stomach cancer incidence was significantly lower, with a summary odds ratio(SOR) after QSR of 0.72 [95% CI=0.64-0.81]. In addition, the SOR of pancreatic cancer tended to be lower at 0.83 [95% CI=0.70-0.98]. The SOR of prostate cancer was slightly higher at 1.03 [0.89-1.19]. Conclusions : Quantitative systematic reviews for the effect of citrus fruit intake on cancer occurrence suggested that lower cancer incidence in Jejudo could be explained by intake of citrus fruits.

제주도 재학생의 아토피 피부염 유병률 추정

배종면,신경수,Bae, Jong-Myon,Shin, Kyung-Sue 대한예방의학회 2009 예방의학회지 Vol.42 No.3

Objectives : The frequency of visiting clinics in Jejudo for treating atopic dermatitis (AD) has been reported to be higher than that for other counties of Korea. The aim of this work was to estimate the prevalence of AD for the students of the primary, middle and high schools in Jejudo, Korea. Methods : We planned to evaluate about 5,000 students, so classes were randomly selected by random systematic sampling methods. The parents of all the students in the selected classes were asked to respond to a structured questionnaire concerned with the prevalence of AD. Results : The prevalence of AD based on ever being diagnosed by a doctor, on currently being diagnosed by a doctor, on ever being treated for AD by a doctor, on currently being treated for AD by a doctor was 25.57% (95% CI=25.3-25.8), 14.67% (95% CI=14.5-14.9), 21.90% (95% CI=21.6-22.2) and 14.41% (95% CI=14.2-14.6), respectively. Conclusions : On comparing the prevalence of AD, the students in Jejudo had a higher number of recurrence events in spite of their lower number of cases. Further studies are needed to evaluate these aspects of AD.

상대생존율

배종면,Bae, Jong-Myon 대한예방의학회 2004 예방의학회지 Vol.37 No.3

Shared decision making: relevant concepts and facilitating strategies

배종면 한국역학회 2017 Epidemiology and Health Vol.39 No.-

preferAs the paradigm in healthcare nowadays is the evidence-based, patient-centered decision making, the issue of shared decision making (SDM) is highlighted. The aims of this manuscript were to look at the relevant concepts and suggest the facilitating strategies for overcoming barriers of conducting SDM. While the definitions of SDM were discordant, several concepts such as good communication, individual autonomy, patient participants, and patient-centered decision-making were involved. Further, the facilitating strategies of SDM were to educate and train physician, to apply clinical practice guidelines and patient decision aids, to develop valid measurement tools for evaluation of SDM processes, and to investigate the impact of SDM.

Thyroid Cancer: We Need a Carcinogen-specific Genome Study

배종면 대한의학회 2015 Journal of Korean medical science Vol.30 No.12

Thyroid cancer is the most common cancer among Koreans with 22.3% annual percentage change in incidence rates between the years of 1999 and 2012 (1). An age-period-cohort analysis showed a strong period effect (2), which supports the hypothesis that the dramatic increase in the incidence rates of thyroid cancer in Koreans is ascribable to over diagnosis due to the spread of diagnostic ultrasound (3,4). The results of a cohort study with residents living near nuclear power plants (NPPs) conducted by Ahn et al. (5), according to which only female thyroid cancer showed significantly higher incidence, can also be explained to be attributable to such over-diagnosis

Introduction of Vaccinomics to Develop Personalized Vaccines in Light of Changes in the Usage of Hantaan Virus Vaccine (Hantavax®) in Korea

배종면 대한예방의학회 2019 예방의학회지 Vol.52 No.5

The Ministry of Food and Drug Safety of Korea made an official announcement in March 2018 that the total number of inoculations of Hantaan virus vaccine (Hantavax®) would change from 3 to 4. Some aspects of this decision remain controversial. Based on the characteristics of Hantaan virus (HTNV) and its role in the pathogenesis of hemorrhagic fever with renal syndrome, it might be difficult to develop an effective and safe HTNV vaccine through the isolate-inactivate-inject paradigm. With the development of high-throughput ‘omics’ technologies in the 21st century, vaccinomics has been introduced. While the goal of vaccinomics is to develop equations to describe and predict the immune response, it could also serve as a tool for developing new vaccine candidates and individualized approaches to vaccinology. Thus, the possibility of applying the innovative field of vaccinomics to develop a more effective and safer HTNV vaccine should be considered.

한국인과 중국인 중증열성혈소판감소증 환자간 임상증상의 차이

배종면 대한응급의학회 2019 대한응급의학회지 Vol.30 No.3

Because the case fatality rate (CFR) between Chinese and Korean patients with severe fever with thrombocytopenia syndrome is different, a comparison of the distribution of clinical manifestations shown at diagnosis in Chinese and Korean patients is needed. In contrast to Chinese patients between 2010 and 2013, Korean patients between 2013 and 2015 showed more cases of diarrhea (54.3% vs. 35.8%) and confusion (25.6% vs. 21.1%). These facts might delay the diagnosis in Korean patients and result in a higher CFR.

Researches of Epigenetic Epidemiology for Infections and Radiation as Carcinogen

배종면 대한예방의학회 2018 Journal of Preventive Medicine and Public Health Vol.51 No.4

In recent years, a number of studies have been reported on the various types of cancer arising from epigenetic alterations, including reports that these epigenetic alterations occur as a result of radiation exposure or infection. Thyroid cancer and breast cancer, in particular, have high cancer burden, and it has been confirmed that radiation exposure or onco-viral infection are linked to increased risk of development of these two types of cancer, respectively. Thus, the environment-epigenetic alteration-cancer occurrence (EEC) hypothesis has been suggested. This paper reviews the trends in research supporting this hypothesis for radiation exposure and onco-viral infection. If more evidences accumulate for the EEC hypothesis from future research, those findings may greatly aid in the prevention, early diagnosis, treatment, and prognosis of the thyroid cancer and breast cancer.