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      • KCI등재

        유동층 공정을 이용한 열화학적 전환 공정의 최신 개발 동향

        박현준,오승석,Ogunsola Nafiu Olanrewaju,Jester Lih Jie Ling,정철승,박한샘,이시훈 한국화학공학회 2023 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.61 No.1

        Increasing of energy demand due to the rapid growth of global population and the development of world economy has inevitably resulted in the continuously increase of fossil fuel usage in the world. However, highly dependence on fossil fuels has necessarily brought about critical environmental issues and challenges such as severe air pollutions and rapid global warming. In order to settle these environmental and energy problems, clean energy generations in the conventional combustion processes have widely adapted in the world. In particular, novel thermochemical conversion processes such as pyrolysis and gasification have rapidly been applied for generating clean energy. Fluidized bed technologies having advantages such as various fuel use, easy continuous operation, high heat and material transfer, isothermal operation, and lower operation temperature are widely adopted and used because they are suitable for thermochemical energy conversion. The latest research trends and important findings in the thermo-chemical conversion process with fluidized bed technologies are summarized in this review. Also, the need for research such as layered materials and substances to reduce fine dust (biomass, natural resource waste, etc.) was suggested. Through this, it is intended to increase interest and understanding in fluidized bed technology and to present directions for solving future challenges in fluidized bed process technology development.

      • KCI등재

        In-situ and highly sensitive detection of epidermal growth factor receptor mutation using nano-porous quartz crystal microbalance

        박현준,유준석,박찬호,장규환,나성수 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.4

        Assessment of epidermal growth factor receptor (EGFR) exon 19 mutations is very important indicator for treating lung cancer patients. In this report, we propose in-situ and highly sensitive detection method of EGFR mutation using quartz crystal microbalance (QCM) and nano-porous structured QCM electrode. The detection is based on the resonance frequency shift of QCM electrode upon DNA hybridization between probe DNA and EGFR mutant DNA (746–750 (del ELREA) in EGFR exon 19). Nano-porous structure is produced on the QCM electrode through simple processes of electrochemical deposition and etching. By using QCM, in-situ detection of EGFR mutation is performed within 30 mins. High sensitivity is achieved by introducing nano-porous structure on a QCM electrode, and the limit of detection (LOD) is 1 nM.

      • KCI등재

        Restoration of Spermatogenesis Using a New Combined Herbal Formula of Epimedium koreanum Nakai and Angelica gigas Nakai in an Luteinizing Hormone-Releasing Hormone Agonist-Induced Rat Model of Male Infertility

        박현준,구연경,박민정,황윤경,황성연,박남철 대한남성과학회 2017 The World Journal of Men's Health Vol.35 No.3

        Purpose: We investigated the protective effect of a mixture of 2 herbal extracts, KH-465, which consisted of Epimedium koreanum Nakai and Angelica gigas Nakai, on spermatogenesis in a luteinizing hormone-releasing hormone (LHRH) agonist-induced rat model of male infertility.Materials and Methods: Seventy-five 12-week-old male Sprague-Dawley rats were randomly divided into 5 groups, containing 15 rats each: a normal control group that received no treatment and 4 experimental groups (I, II, III, and IV) in which an LHRH agonist was administered for 4 weeks to induce spermatogenic failure. Group I received distilled water, and groups II, III, and IV received 200 mg/kg/day of KH-465, 400 mg/kg/day KH-465, and depo-testosterone for 4 weeks, respectively. Weight changes of the testis and epididymis, sperm count motility, and levels of testosterone (T), free T, follicle-stimulating hormone (FSH), luteinizing hormone (LH), superoxide dismutase (SOD), and 8-hydroxy-2’-deoxyguanosine (8-OHdG) were estimated.Results: Body, testis, and epididymis weight showed no significant differences among the control and experimental groups. Treatment with KH-465 increased the sperm count and motility. Serum hormone levels of T, free T, and FSH were not significantly different in the experimental groups, while the LH level was higher than in the LHRH agonist-induced control group, but not to a significant extent. Levels of SOD were higher and 8-OHdG were lower in the groups that received KH-465 than in the LHRH agonist-induced control group.Conclusions: Our results suggest that KH-465 increased sperm production via reducing oxidative stress and had a positive effect in a male infertility model.

      • KCI등재

        Changing Relationships between Education and Marriage among Korean Women

        박현준,이재경,조인경 한국사회학회 2013 韓國社會學 Vol.47 No.3

        Using the data from the 1-percent microdata sample of 2010 Census (N = 107,741), we examine changing relationships between education and first marriage across Korean women of three birth cohorts born in 1951-60, 1961-70, and 1971-80. We apply discrete-time hazard models to the person-year data, allowing the effect of women’s educational attainment on the risk of marriage to fully vary across cohorts and over duration. Women of younger cohorts have increasingly delayed and forgone marriage regardless of educational levels. However, the trend toward later and less marriage has been particularly significant among the lowest educated. In the result, for the youngest cohort, the percentage of women who remained single by the age 39 is highest at both ends of educational attainment. This contrasts the pattern among the oldest cohort where there was a linearly negative relationship between education and marriage, consistent with the findings in other East Asian countries.

      • Growing Up in a Single-Parent Family in Korea

        박현준,주동범 (토론자) 한국직업능력개발원 2005 한국교육고용패널 학술대회 Vol.2005 No.1

        한국 교육고용패널의 1차년도 자료를 이용해, 본 논문은 한국 사회에서 가족구조가 청소년들의 교육열망 (educational aspiration)과 학교 태도 (school disengagement)에 미치는 영향을 알아본다. 한부모가족 (single-parent families)의 상이함을 염두에 두고 네가지 유형의 한부모가족을 구분하여 (이혼으로 인한 편부가족, 사별로 인한 편부가족, 이혼으로 인 한 편모가족, 사별로 인한 편모가족) 그러한 가족구조에 있는 청소년들과 두부모가족 (two-biological-parent families)의 청소년들의 4년제 대학 열망 정도와 학교태도를 비교한다. 분석결과, 한부모가족구조의 부정적인 효과를 확인할 수 있었으며 특히 이혼으로 인한 한부모가족 구조의 부정적인 효과가 두드러진다. 사별보다는 이혼으로 인한 한부모가족 형성이 더욱 부정적인 효과를 가진다는 사실은 편부와 편모가족 모두에게서 발견된다. 이러한 한부모가족의 효과의 상당 부분은 한부모가족의 낮은 가구임금에서 기인하며 부모의 양육태도 역시 일정한 부분을 설명한다 (하지만 양육태도는 편모가족의 효과를 전혀 설명하지 못한다). 최근의 이혼율의 급속한 증가는 한국 사회에서 가족구조가 불평등의 중요한 기제가 될 수 있음을 시사한다.

      • 뇌손상 예측을 위한 3차원 시뮬레이션 모델의 충격 방향에 따른 해석 결과 비교

        박현준,심희동,안장원,현예나,양석조 대한기계학회 2021 대한기계학회 춘추학술대회 Vol.2021 No.4

        본 연구는 뇌-머리 구조를3차원 모델로 제작하고 충격 시뮬레이션을 통해 뇌손상을 예측하기 위한연구이다. 뇌척수액(CSF)부분을 유체로 설정하고 ALE(Arbitrary Lagrangian-Eulerian)방식으로 해석할 수 있도록 3차원 모델을 제작하였으며, 머리에 충돌하는 질량체(Impactor) 속도를 조절하여 충격발생 시 발생하는 충격력을 기준으로 입력 값을 설정하였다. 여러 방향에서 충격을 주어 뇌에서 측정되는 최대압력 데이터로 뇌손상을 예측한다. Nahum.A는 머리 충격시험을 사체를 대상으로 실험을 하였으며, 시뮬레이션의 객관성을 확보하기 위하여 사체실험 데이터를 활용하였다. Nahum.A의 사체실험 방법을 시뮬레이션으로 모사하여 Nahum.A가 실험한 사체실험 데이터와 해석 결과값인 시뮬레이션 데이터 비교를 통해 모델의 타당성을 검증하였다. 충격 방향에 따라 뇌의 위치별(Front, Parietal, Occipital, Fossa)압력 분포가 달라지는 경향을 확인하여, 동일한 충격이 외부로부터 가해질 때 뇌손상에 가장 위협적인 충격 방향을 예측하는 연구를 수행하였다.

      • KCI등재

        Reappraisal of Supraorbital Sensory Nerve Conduction Recordings: Orthodromic and Antidromic Techniques

        박현준,김성훈,이세광,이항재,권희규 대한재활의학회 2016 Annals of Rehabilitation Medicine Vol.40 No.1

        Objective To establish a supraorbital nerve sensory conduction recording method and assess its usefulness. Methods Thirty-one healthy subjects without a history of trauma or neurological disease were recruited. For the orthodromic procedure, the recording electrode was attached immediately superior to the supraorbital notch. The stimulation electrode was placed on points along the hairline which evoked the largest sensory nerve action potentials (SNAPs). The antidromic sensory response was recorded after switching the recording and stimulating electrodes. The measured parameters were onset latency, peak latency, and baseline to peak amplitude of the SNAPs. The electrophysiological parameters of the bilateral supraorbital nerves were compared. We also recruited two patients who had sensory deficits on one side of their foreheads because of laceration injuries. Results The parameters of orthodromically recorded SNAPs were as follows: onset latency 1.21±0.22 ms (range, 0.9–1.6 ms), peak latency 1.54±0.23 ms (range, 1.2–2.2 ms), and baseline to peak amplitude 4.16±1.92 V (range, 1.4–10 V). Those of antidromically recorded SNAPs were onset latency 1.31±0.27 ms (range, 0.8–1.7 ms), peak latency 1.62±0.29 ms (range, 1.3–2.2 ms), and baseline to peak amplitude 4.00±1.89 V (range, 1.5–9.0 V). There was no statistical difference in onset latency, peak latency, or baseline to peak amplitude between the responses obtained using the orthodromic and antidromic methods, and the parameters also revealed no statistical difference between the supraorbital nerves on both sides. Conclusion We have successfully recorded supraorbital SNAPs. This conduction technique could be quite useful in evaluating patients with supraorbital nerve lesions.

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