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치매 노인을 돌보는 노년기 배우자의 돌봄 부담감이 생활만족도에 미치는 영향: 사회적지지의 조절효과
박주희,Park, Ju-Hee 한국가족자원경영학회 2021 가족자원경영과 정책 Vol.25 No.4
The purpose of this study was to explore the effects of perceived care-related burden and social support on life satisfaction and the moderating effect of social support from elderly spouses caring for their elderly partners with dementia. The subjects were 165 spouses aged over 60 years, caring for their elderly partners afflicted with dementia, and living in Seoul and Gyeonggi Province. The analysis results are as follows: First, the quantified total care-related burden shouldered by the participant spouses was 3.76 points (SD = .57), which was slightly higher than the median value. In the case of social support, informal support was scored 2.65 (SD = .78), and formal support was scored 2.60 (SD = .77), which was lower than the median value. Life satisfaction earned a score of 3.11 points (SD = .78), which somewhat exceeded the median. Second, subjective health status, income level, burden from social activity, and informal support influenced life satisfaction. Put differently, the higher the subjective health status of a caring spouse, the higher the income level, the lower the social activity burden, the stronger the informal support, and the greater the life satisfaction. Third, the interaction terms of social activity burden and informal support were significant. Therefore, informal support had a moderating effect on the relationship between social activity burden and life satisfaction among the elderly with dementia. In other words, even though the caring spouses experienced a burden from social activities, the higher the frequency with which they accessed informal support, the lower the decrease in life satisfaction.
제 1상 임상시험에서 멈춤 규칙을 이용한 수정된 최대허용용량 추정법
박주희,김동재,Park, Ju Hee,Kim, Dongjae 한국데이터정보과학회 2012 한국데이터정보과학회지 Vol.23 No.6
제 1상 임상시험의 주목적은 신약 후보 물질의 독성을 평가하여 부작용 및 안전하게 투여할 수 있는 약물의 적정한 용량인 최대허용용량의 추정이다. 기존에 최대허용용량을 추정하는 방법에는 표준방법 (Storer, 1989; Korn 등, 1994) 그리고 NM방법 (Lee와 Kim, 2012) 등이 있다. 본 연구에서는 많은 피험자들이 낮은 용량에 많이 할당되는 점을 보완하고 기존의 최대허용용량 추정법보다 적은 수의 피험자로 실험하기 위해서 기존 최대허용용량 추정법을 수정한 멈춤 규칙을 적용시킨 추정법을 제안하였다. 기존의 방법들과 새롭게 제시한 방법을 모의실험을 통하여 비교하였다. Phase I clinical trials are designed to identify an appropriate dose; the maximum tolerated dose, which assures safety of a new drug by evaluating the toxicity at each dose-level. The adjusted maximum tolerated dose estimation is presented by stopping rule in phase I clinical trial on this research. The suggested maximum tolerated dose estimation is compared to the standard method3 and NM method using a Monte Carlo simulation study.
융복합 시대의 사회적 자본이 노년기 우울에 미치는 영향
박주희,Park, Ju-Hee 한국사물인터넷학회 2021 한국사물인터넷학회 논문지 Vol.7 No.3
본 연구의 목적은 사회적 신뢰, 네트워크, 규범, 참여 등의 융복합 시대의 사회적 자본이 노년기에 경험할 수 있는 우울에 어떠한 영향을 미치는지를 탐구하는데 있다. 본 연구의 대상은 서울시와 경기도 지역에 거주하는 65세 이상 노인 302명이다. 분석결과, 노인이 교육수준이 낮고 종교가 없으며 사회적 자본의 네트워크와 규범 수준이 낮을수록 우울이 높은 것으로 나타났다. 본 연구에서 우울에 가장 영향력 있는 변인으로 사회적 자본의 네트워크로 나타났다. 본 연구를 통해 노년기 우울을 완화하기 위해서는 우리 사회 전체의 네트워크를 활성하고 확대하는 노력이 요구된다. 노인의 네트워크 활성화를 위해 지역사회의 활동공간 확장과 다양한 융복합 컨텐츠의 프로그램 개발, 노인교육프로그램의 확대가 필요하다. The purpose of this study is to analyze the effect of social capital include networks, trust, norms, and participation on depression in the elderly in the era of convergence. The subjects of this study were 302 senior citizens aged 65 and over who are living in Seoul and Gyeonggi Province. The results are follows. Depression was more severe in the elderly with lower level of education, no religion, and lower social capital including networks and norms. In this study, social networks were found to be the most important contributor to depression. In order to alleviate depression in the elderly through this study, efforts to activate and expand the network of the entire society are required. In other words, it is necessary to expand the activity space of local community, develop programs for various convergence contents, and expand education programs for the elderly in order to vitalize the network of the elderly.
중년기 기혼남녀의 가족생활 스트레스, 가족가치관이 결혼안정성에 미치는 영향
박주희,Park, Ju-Hee 한국가족자원경영학회 2018 가족자원경영과 정책 Vol.22 No.4
The purpose of this study was to explore the effects of family life stress and family values on marital stability among middle-aged couples. The subjects included a total of 302 men and women aged 45-64 who had been married for more than 20 years and were living in Seoul. The collected data were statistically analyzed with the SPSS 21.0 Package. First, Cronbach's alpha was calculated to measure the reliability of the scale that assessed the variables of the research model. Then, mean and standard deviation were calculated to determine the degrees of family life stress, family values, and marital stability among the subjects. Finally, a hierarchical multiple regression analysis was performed to identify factors that affected the subjects' marital stability. The results revealed that the level of family life stress in middle-aged married men and women was slightly higher than the mean value. Of all the sub-scales of family life stress, the subjects were found to experience the most stress from factors related to financial pressure, followed by family relationships, a sense of loss within a family, and work-family compatibility. Therefore, financial problems were one of the critical stressors for middle-aged married couples. Also, for this demographic, the levels of family values and marital stability were higher than the medians. The factors affecting marital stability in middle-aged couples were identified to be family relationship stress, financial stress, subjective economic status, family values, stress related to work-familycompatibility,religion,andage.Thedegreeofmaritalstabilitywashigherinmiddle-agedcouplesa stheirstresslevelsfromfamilyrelationshipsandfinancialproblemswerelower.Moreover,thehigherthes ubjectiveeconomicstatusandthemoretraditionalthefamilyvalues,thehigherthedegreeofmaritalstabili ty.Finally,marriedcoupleswhowerereligioushadalowerlevelofstressfromwork-family compatibility, and the younger the couples, the higher the degree of marital stability.
박주희,권영혁,박준봉,정종혁,신승일,허익,Park, Ju-Hee,Kwon, Young-Hyuk,Park, Joon-Bong,Chung, Jong-Hyuk,Shin, Seung-Il,Herr, Yeek 대한치주과학회 2008 Journal of Periodontal & Implant Science Vol.38 No.1
Purpose: The purpose of this study was to evaluate exophytically vertical bone formation in the mandibular premolar area of beagle dogs by the concept of guided bone regeneration with a titanium reinforced e-PTFE membrane combined with human demineralized freeze-dried bone. Materials and Methods: Four one-year old beagle dogs were divided into control and experimental group. All mandibular premolars were extracted and surgical vertical defects of 5 mm in height were created in the extracted sockets. At 8 weeks after the extraction, TR e-PTFE membrane sized with 8 mm in length, 5 mm in width, and 4 mm in height was placed on the decorticated mandible, fixed with metal pins and covered with full-thickness flap and assigned as control group. In experimental group, decorticated mandibule was treated with TR e-PTFE membrane and human demineralized freeze-dried bone. The animals were sacrificed at 16 weeks after the regenerative surgery, and new bone formation was assessed by histomorphometric as well as statistical analysis. Results: Average of new bone formation was 38% in the control group, whereas was 25% in the experimental group (p<0.05). Average of connective tissue formation was 42% in the experimental group, whereas was 30% in the control group (p<0.05). The lamellar bone formation with haversian canals was observed in the both groups. In the experimental group, the particles of human demineralized freeze-dried bone were observed after 16 weeks and complete resorption of graft was not observed. Conclusion: On the basis of these findings, we conclude that titanium reinforced e-PTFE membrane may be used alone for vertical guided bone regeneration, but demineralized freeze-dried bone has no additional effect on vertical guided bone regeneration.
박주희 ( Ju Hee Park ),유광호 ( Kwang Ho Yoo ),한태영 ( Tae Young Han ),이갑석 ( Kap Sok Li ),서성준 ( Seong Jun Seo ),홍창권 ( Chang Kwun Hong ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.9
Urticaria pigmentosa (UP) is the most common variant of cutaneous mastocytosis. Primarily a disease of childhood, in over one-half of the cases onset is before 2 years of age, and in 90%, the disease is confined to the skin. UP precedes the diagnosis of systemic mastocytosis and is more common in adults than in children. Therefore, systemic examination should be performed in patients with UP. We report a case of adult-onset UP with systemic involvement. (Korean J Dermatol 2009;47(9):1060∼1062)