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원자력시설 해체 규제요건과 기술기준 연계를 통한 요구관리
박희성,박종선,홍윤정,김정국,홍대석,Park, Hee Seoung,Park, Jong Sun,Hong, Yun Jeong,Kim, Jeong Guk,Hong, Dae Seok 한국시스템엔지니어링학회 2018 시스템엔지니어링학술지 Vol.14 No.1
This paper discusses decommissioning procedure requirements management using requirement engineering to systematically manage the technical requirements and criteria that are required in decontamination and decommissioning activities, and the regulatory requirements that should be complied with in a decommissioning strategy for research reactors and nuclear power plants. A schema was designed to establish the traceability and change management related to the linkage between the regulatory requirements and technical criteria after classifying the procedures into four groups during the full life-cycle of the decommissioning. The results confirmed that the designed schema was successfully traced in accordance with the regulatory requirements and technical criteria required by various fields in terms of decontamination and decommissioning activities. In addition, the changes before and after the revision of the Nuclear Safety Act were also determined. The dismantling procedure requirement management system secured through this study is expected to be a useful tool in the integrated management of radioactive waste, as well as in the dismantling of research reactor and nuclear facilities.
한약조제 지침서 100처방을 구성하는 생약 성분별 안전성과 상호작용에 대한 연구
김정은(Jeong Eun Kim),박종선(Jong Sun Park),김도연(Do Yeon Kim),류예진(Yae Jin Yu),김지은(Ji Eun Kim),임성실(Sung Cil Lim) 대한약학회 2021 약학회지 Vol.65 No.2
Currently in Korea, hundreds of herbs can be prescribed by an oriental medicine doctor or sold by a pharmacist to treat mild diseases or improve health conditions for the same indication. And it can be happened to the same patient at the same time. However, there is no monitoring system for the oriental medical doctors and pharmacists to check the drug interaction or duplicate the administration. Herbal medicine contains pharmacologically bioactive ingredients, and when administered without assessment of the patient s disease and/or preexisting health conditions, it may overdose, duplicate, or showed unexpected harmful effects. The study was conducted through collecting information based on the secondary research using PubChem, PubMed, etc. and the evaluation of various source of additional primary information through literature survey. The result showed if 151 herbs use without caution under supervision or monitoring, those may revealed pregnancy contraindication, severe drug indications, liver, renal, cardiovascular, and/or gastrointestinal (GI) functions and blood glucose, etc. Only 61 herbs were identified to be safe for pregnant women and the most frequency side effect is GI problems. In conclusion, the result is very meaningful but available information is still limited and need to further research in future.
국내 폐 랑게르한스세포 조직구증(Pulmonary Langerhans Cell Histiocytosis)의 임상양상
김철 ( Chul Kim ),정성환 ( Sung Hwan Jeong ),심재정 ( Jae Jeong Shim ),차승익 ( Seung Ick Cha ),손춘희 ( Choon Hee Son ),정만표 ( Man Pyo Chung ),박혜윤 ( Hye Yoon Park ),김영환 ( Young Whan Kim ),박종선 ( Jong Sun Park ),어수택 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.66 No.2
Background: Pulmonary Langerhans cell histiocytosis (PLCH) is characterized by a proliferation of Langerhans cells and this results in granulomas that involve multiple organs of the body. Because the incidence of PLCH is very low in Korea and worldwide, collecting the clinical data of patients with PLCH nationwide is needed to determine the clinical features of Korean patients with PLCH. Methods: The patients with PLCH confirmed by biopsy at any body site were included and the patients should have lung lesions present. A questionnaire that had items on the symptoms, lung function tests, the roentgenographic findings and the treatment was collected retrospectively at a Korean ILD Research Meeting. Results: A total of 56 cases were collected. The number of males and females was 48 and 8, respectively, and their median age was 43 years (range: 18∼67 years). The patients were current or ex-smokers in 79% of the cases. The most frequent symptom was coughing (39%), followed in decreasing order by dyspnea (38%), sputum (20%) and chest pain (20%). Pneumothorax was observed in 16 (29%) patients. Lung function tests showed a normal, restrictive, mixed or obstructive pattern in 26 (61%), 7 (16%), 7 (16%) and 3 patients (7%), respectively. Nodular-cystic lesion was most frequently observed in 59% of the patients on HRCT. The lung lesions were located in the middle and upper lobes in almost the cases. The median follow-up period was 90 months (range: 1∼180 months) and only two patients died during this period. Conclusion: This study provides a national survey of the patients with PLCH during a long follow-up period.