부분 구문 분석 결과에 기반한 두 단계 부분 의미 분석 시스템

박경미,문영성,Park, Kyung-Mi,Mun, Young-Song 한국정보처리학회 2010 정보처리학회논문지B Vol.17 No.1

부분 의미 분석 시스템은 문장의 구성 요소들이 술어와 갖는 관계를 분석하는 것으로 문장에서 술어의 주체, 객체, 도구 등을 나타내는 의미 논항을 확인하게 된다. 본 논문에서 개발한 부분 의미 분석 시스템은 두 단계로 구성되어 있는데, 먼저 부분 구문 분석 결과로부터 의미 논항의 경계를 찾는 의미 논항 확인 단계를 수행하고 다음으로 확인된 의미 논항에 적절한 의미역을 부착하는 의미역 할당 단계를 수행한다. 순차적인 두 단계 방법을 적용하는 것에 의해서, 학습 성능 저하의 주요한 원인인 클래스 분포의 불균형 문제를 완화할 수 있고, 각 단계에 적합한 자질을 선별하여 사용할 수 있다. 본 논문에서는 PropBank 말뭉치에 기반한 CoNLL-2004 shared task의 데이터 집합 및 평가 프로그램을 사용하여 각 단계가 시스템의 전체 성능에 기여하는 정도를 보인다. A shallow semantic parsing system analyzes the relationship that a syntactic constituent of the sentence has with a predicate. It identifies semantic arguments representing agent, patient, instrument, etc. of the predicate. In this study, we propose a two-phase shallow semantic parsing model which consists of the identification phase and the classification phase. We first find the boundary of semantic arguments from partial syntactic parsing results, and then assign appropriate semantic roles to the identified semantic arguments. By taking the sequential two-phase approach, we can alleviate the unbalanced class distribution problem, and select the features appropriate for each task. Experiments show the relative contribution of each phase on the test data.

감초 약침액의 항암 및 면역활성에 미치는 영향

박경미,조경희,손윤희,임종국,남경수,Park, Gyung-Mi,Cho, Kyoung-Hee,Shon, Yun-Hee,Lim, Jong-Kook,Nam, Kyung-Soo 한국생약학회 2000 생약학회지 Vol.31 No.1

Glycyrrhizae Radix aqua-acupuncture solution (GRAS) and Glycyrrhizae Radix water-extracted solution (GRWS) were prepared and tested for organ toxicities, antitumor activities, and immunomodulatory effects. The organ-toxicity of GRAS to male ICR mice was studied by the measurements of glutamic oxaloacetic transaminase (GOT), glutamic pyruvate transaminase (GPT), lactate dehydrogenase (LDH), and alkaline phosphatase (ALP-s) activities after injection of GRAS for 7 days. The activities of GOT, GPT, LDH, ALP-s were decreased with GRAS. It was shown to possess considerable toxicity toward various tumor cell lines. Concentration of GRAS at 1.5g/ml and 3g/ml resulted in more than 80% inhibition of growth in Ehrlich ascites tumor cells (EATC), Hepa1c1c7, and HeLa cells. Toxicity of GRAS to A549 revealed that 68% inhibition of growth. GRWS at the concentration of 3g/ml showed more than 80% inhibition of growth with EATC, Hepalclc7, A549 and HeLa. In morphological study, the number of cells were decreased, and the shape of cells was round-form in EATC, Hepalclc7, A549 and HeLa cells with GRAS. Administration of GRAS inhibited the growth of EATC in vivo. Mice given EATC at 1.5g/ml or 0.3g/ml GRAS had 16.7% to 50% survival after 21 days. GRAS increased the proliferation of T and B cells and the cytolytic activity of purified T cell. The biosyntheses of nucleic acid and protein of EATC, Hepalclc7, A549 and HeLa cells were inhibited by GRAS.

트리플루살 캅셀의 생물학적 동등성 평가

박경미(Kyung Mi Park),이미경(Mi Kyung Lee),임수정(Soo Jeong Lim),김종국(Chong Kook Kim),박정숙(Jeong Sook Park),김진기(Jin Ki Kim),최성희(Sung Hi Choi),민경아(Kyung Ah Min) 한국응용약물학회 2001 Biomolecules & Therapeutics(구 응용약물학회지) Vol.9 No.4

N/A The bioequivalence of two triflusal products was evaluated with 20 healthy volunteers following single oral dose according to the guidelines of Korea Food and Drug Administration (KFDA). Trisal^? capsule (Whanin Pharm. Corp., Korea) and Disgren^? capsule (Myung-In Pharm. Corp., Korea) were used as test product and reference product, respectively. Both products contain 300㎎ of trifusal. One capsule of test product or reference product was orally administered to the volunteers, respectively, by randomized two period crossover study (2×2 Latin square method). Blood samples were taken at predetermined time intervals for 4 hours and the determination of trifusal was accomplished using semi-microbore HPLC equipped with automated column switching system. The analytical method with HPLC was validated according to the Bioanalytic Method Validation guideline by FDA prior to determining the plasma samples. The pharmacokinetic parameters (AUC_(0-4h), C_max, and T_max) were calculated and ANOVA test was utilized for statistical analysis of parameters. As a result of the assay validation, the limit of quantification of trifusal in human plasma by current assay procedure was 50 ng/ml using 500 ㎕ of plasma. The accuracy of the assay was from 97.76% to 116.51% while the intra-day and inter-day coefficient of variation of the same concentration range was less than 15%. Average drug concentration at the designated time intervals and pharmacokinetic parameters calculated were not significantly different between two products (p>0.05). The difference of mean AUC_(0→4hr), C_max, and T_max between the two products (2.92, 4.39, and -2.44%, respectively) were less than 20%. The power (1-β) and treatment difference (Δ) for AUC_(0→4hr) and C_max were more than 0.8 and less than 0.2, respectively. Although the power for T_max was under 0.8, T_max, of the two products was not significantly different from each other (p>0.05). These results satisfied the criteria of KFDA guideline for bioequivalence, indicating the two products of triflusal were bioequivalent.

소아 환자에서의 괴사성 폐렴의 임상적 고찰

박경미 ( Kyung Mi Park ),손승국 ( Seung Kook Son ),김혜영 ( Hye Young Kim ),김용우 ( Yong Woo Kim ),황재연 ( Jae Yeon Hwang ),박희주 ( Hee Ju Park ) 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.3

Purpose: Necrotizing pneumonia (NP) is a complication of invasive pneumonia. Few studies have reported on the clinical features of NP in children. Methods: Nineteen patients with NP who were admitted to Pusan National University Hospital and Pusan National University Children``s Hospital between December 2008 and March 2013, were studied in terms of sex, age at diagnosis, clinical characteristics, detected organisms, radiologic findings, treatments and clinical outcomes. Results: Twelve patients (63.2%) were males and seven patients (36.8%) were female. Eight patients (44.4%) were younger than 5 years of age, seven patients (38.9%) were at 6-10 years of age and four patients (21.1%) were older than 11 years of age. Most patients had fever and cough at the time of diagnosis. Minorganism were identified in 9 cases (47.4%): Mycoplasma pneumonia in 4 (21.1%), Streptococcus pneumonia in 1(5.3%), Staphylococcus aureus in 1 (5.3%), G+cocci in 1 (5.3%), and M. pneumonia + S. pneumoniae coinfection in 2 (10.5%). The diagnosis of NP was established by computerized tomography. Cavitary necrosis was shown in all patients, and pleural effusion was shown in 15 patients (78.9%). Six patients (31.6%) presented local atelectasis and 2 patients (10.5%) presented pneumothorax. Five patients (26.3%) treated with only antibiotics were cured completely. Invasive treatment was needed by 14 patients (73.7%): 10 patients (52.6%) needed chest tubing, and 5 patients (26.3%) needed surgery. Only one patient (5.3%) expired. Conclusion: NP is a rare complication of pneumonia in children and has a good prognosis, typically resolving completely with medical treatment alone. However, patients who present with the worsening of clinical status or pleural complications despite the use of appropriate antibiotics should be evaluated for surgical indications.

예수/예수운동과 가정

박경미(Park, Kyung Mi) 한국신약학회 2018 신약논단 Vol.25 No.3

이 글에서는 예수/예수운동에서 ‘가정’이 지니는 의미를 확인하고자 했다. 많은 학자들이 복음서의 탈가정적인 본문들에 근거해서 예수/예수운동에서 ‘가정’의 의미를 소극적으로 해석해왔다. 대표적으로 제자부름에 관한 본문들에서 예수는 제자가 될 사람들에게 가족에 대한 의무와 연결을 끊고 소유물과 생업을 포기하며 가정의 보호까지 포기하라고 요구한다.(Q 9:59-60; Q 12:51-53, Q 14:26) 이 글에서는 이처럼 가정을 해체하고 파괴하는 것으로 해석될 수 있는 예수의 말씀들과 예수의 하나님나라 운동의 거점이자 중심으로서 전통적인 가정의 재건과 갱신을 시사하는 말씀들 간의 긴장관계를 어떻게 해석할지 살펴보았다. 그리고 예수의 하나님나라 운동의 혁신적 비전이 가정이라는 가부장적이고 관습적인 사회제도와 관련해서 어떠한 방식으로 구체화되는지도 밝히고자 했다. 그럼으로써 예수/예수운동에서 ‘가정’이 지니는 적극적 의미를 재건하고자 했다. This study reexamines the meaning of ‘family’ in the Jesus/Jesus movement. Scholars have tended to devalue the notion of family in the Jesus/Jesus movement by pointing to the anti-familial texts in the synoptic gospels. In particular, scholars have highlighted the texts where Jesus calls on his disciples to sever familial bonds and duties, and give up their property, occupations, and protection from their families (Q 9:59-60; Q 12:51-53, Q 14:26). This study endeavors to interpret the tension between two types of words that Jesus uses words that seem to advocate for the deconstruction or destruction of the family/household and words that emphasize the reconstruction or restoration of the traditional family or household. Furthermore, this study aims to determine how the radical social vision of the Jesus/Jesus movement has been actualized in relation to the household as a conventionally patriarchal social system. Through these efforts, this study seeks to verify the significance of family as a central metaphor of and material basis for the Jesus/Jesus movement.

전체주의 시대의 종교와 여성 : ‘유토피아적 부정’과 여성해방적 종교비판

박경미(Kyung-Mi Park) 계명대학교 여성학연구소 2008 젠더와 문화 Vol.1 No.-

‘사유’라는 가장 인간적인 행위가 효율과 합리성의 미명 하에 조롱당하는 오늘의 현실 속에서 인간적인 세계를 향한 유토피아적 비전을 보존하는 보루로서 종교와 비판적 여성해방론은 어떻게 만날 수 있는가? ‘화폐적 보편성’에 의해 획일화 된 자본주의라는 이름의 전체주의 시대를 살아가는 우리들에게 비판적 관점에서 이루어지는 종교적 성찰은 오늘날 억압과 지배의 형태에 대한 어떠한 의미 있는 분석과 비판을 제공할 수 있는가? 그것은 비판적 여성해방론과 어떻게 근접할 수 있는가? 이러한 질문들에 대해 성찰하는 것이 이 글의 관심사이다. 무엇보다도 자본주의 산업사회가 지니는 억압적 성격에 대한 ‘비판이론’의 분석과 전망이 종교와 여성해방론을 잇는 다리 역할을 할 수 있을 것으로 보인다. 데일리나 뤼터, 피오렌자 같은 주요 여성신학자들은 드러내놓고 언급하지는 않았지만 실질적으로는 ‘비판이론’을 여성해방적 관점에서 비판적으로 재해석해서 기독교에 대한 여성해방적 비판이론을 전개했다. 비종교적인 비판이론과 여성신학이 결합될 수 있었던 것은 양자가 공유했던 유토피아적 관념 때문이었을 것이다. 비판이론과 여성해방신학은 각기 희망의 근거가 다르긴 해도, 둘 다 한 번도 실현된 적이 없는 보다 나은 세계의 실제적인 가능성에 대한 희망을 가지고 있다. 그리고 이러한 ‘유토피아적 관점’은 비판이론과 여성해방적 종교비판이 자본주의 근대 사회에 대한 급진적인 문명비판 작업을 할 수 있게 만드는 동력이 된다. 이 글은 비판적 여성해방론과 종교가 공유할 수 있는 지점, 즉 유토피아적 관점을 지지하고 해명하는 입장에서 씌어졌다. How can religion and critical feminism meet and coexist as a stronghold that preserves an utopian vision for the humane world in the reality that “thinking”, the most humanlike activity has become a stupid thing before the claim for the efficiency and rationality? The main purpose of this article is not to sketch out or explain about the women's place in each religion or their treatment of women. Rather, the focus is on reflecting the following questions: What meaning does the critical reflection on religion have in relation to the critical analysis of the forms of oppression and domination in this totalitarian and capitalistic society that is maintained by “monetary universality”? And how can this critical reflection on religion meet with feminism? These will be the leading questions in this article. It seems that the analysis and prospect of the “critical theory” on the suppressive characters and self-destructive aspects inherent in the capitalist industrial society can be the bridge between critical theory of religion and feminism. The leading feminist theologians such as Mary Daly, Rosemary Ruether and Elizabeth Schussler Fiorenza have not stated clearly that they accepted the “critical theory”. However, they have critically reinterpreted it in the light of feminism and developed feminist critical theories of Christianity. Probably one of the important elements that unites non-religious critical theory with feminist theology is the utopian ideal they share. In other words, although their grounds of hope are different from each other, both of them have the same hope for the possibility of a better world that has never been come true. This ‘utopian perspective’ becomes the power that enables the critical theory and feminist religious criticism to radically criticize the modern capitalist society. Synthesizing the three, that is, the critical theory, feminism, and theology into one theory is not the aim of this article. It is for supporting and elucidating the utopian perspective, the point that the critical feminism and religion can share with.

제제설계의 최근 진보 : 약물 수용체로서 지질함유 vesicles 의 응용

박경미(Park Kyung Mi),(Kim Chong Kook) 한국약제학회 1999 과학의 달 기념 심포지움 Vol.- No.11

절 경계와 트리 거리를 사용한 2단계 부분 의미 분석 시스템

박경미(Kyung-Mi Park),황규백(Kyu-Baek Hwang) 한국정보과학회 2010 정보과학회 컴퓨팅의 실제 논문지 Vol.16 No.5

본 논문은 최대 엔트로피 모형에 기반한 두 단계 부분 의미 분석 방법을 제안한다. 먼저, 의미논항의 경계를 인식하고, 그 다음 단계에서 확인된 논항에 적절한 의미역을 할당한다. 두 단계 부분 의미분석에서는 두 번째 단계인 논항 분류가 논항 확인 단계의 결과에 기반하여 수행되기 때문에 논항 확인의 성능이 매우 중요하다. 본 논문은 논항 확인의 성능을 향상시키기 위하여 논항 확인의 전처리 단계에 구문 지식을 통합한다. 구체적으로, 절 인식 결과로부터 술어의 인접절 및 상위절들을 확인하고, 구문 분석 결과로부터 술어의 부모 노드로부터 구문 구성 요소의 부모 노드까지의 트리 거리를 추출하여 전처리 단계에서 활용한다. 실험을 통해, 구문 지식을 활용하는 것이 부분 의미 분석 성능에 기여함과 제안하는 두 단계 방법이 한 단계 방법보다 우수한 성능을 낼 수 있음을 보인다. In this paper, we present a two-phase shallow semantic parsing method based on a maximum entropy model. The first phase is to recognize semantic arguments, i.e., argument identification. The second phase is to assign appropriate semantic roles to the recognized arguments, i.e., argument classification. Here, the performance of the first phase is crucial for the success of the entire system, because the second phase is performed on the regions recognized at the identification stage. In order to improve performances of the argument identification, we incorporate syntactic knowledge into its pre-processing step. More precisely, boundaries of the immediate clause and the upper clauses of a predicate obtained from clause identification are utilized for reducing the search space. Further, the distance on parse trees from the parent node of a predicate to the parent node of a parse constituent is exploited. Experimental results show that incorporation of syntactic knowledge and the separation of argument identification from the entire procedure enhance performances of the shallow semantic parsing system.

간호대학생의 임상실습 스트레스, 사회적 지지, 현장실습 적응에 관한 연구

박경미(Park kyung Mi) 학습자중심교과교육학회 2020 학습자중심교과교육연구 Vol.20 No.8

본 연구는 간호대학생의 임상실습 스트레스, 사회적 지지 및 현장실습 적응간의 관계를 파악하고 현장실습 적응에 영향을 미치는 요인을 확인하는데 그 목적이 있다. 연구대상은 간호대학생 3,4학년 학생이며 구조화된 설문지를 사용하여 2019년 5월 3일부터 6월 3일까지 자료를 수집하였다. 자료처리는 SPSS 프로그램을 활용하였으며 t-test와 ANOVA, Pearson’s correlation, 다중회귀분석을 실시하였다. 연구결과 간호대학생의 임상실습 스트레스, 사회적 지지, 현장실습 적응간에는 유의한 상관관계가 있었다. 회귀분석결과 임상실습 스트레스 중 실습환경과 환자와의 갈등, 사회적 지지 중 평가적 지지와 정서적 지지가 현장실습 적응에 영향을 미치는 변수로 나타났으며 이 변수들은 현장실습 적응을 46% 설명하였다. 본 연구 결과를 토대로 현장실습 적응을 높이기 위해 임상실습 중 실습환경 및 환자갈등의 스트레스와 사회적지지 중 평가적, 정서적 지지를 고려한 프로그램의 개발이 필요하다 The purpose of this study is to identify the relationship between clinical practice stress, social support and field practice of nursing students and to identify the factors affecting field practice. The subjects of this study were nursing students in grades 3 and 4 and collected data from May 3 to June 3, 2019 using a structured questionnaire. SPSS program was used for data processing and t-test, ANOVA, Pearson s correlation, and multiple regression analysis were performed. As a result, there was a significant correlation between clinical practice stress, social support, and field adaptation of nursing students. As a result of regression analysis, the practice environment, the conflict with patients, the evaluation support and the emotional support among the social support were the variables influencing the field practice adaptation. These variables accounted for 46% of the field practice adaptation. Based on the results of this study, it is necessary to develop a program that considers the emotional and emotional support of the practice environment and patient conflict and the social support during clinical practice in order to improve on-site practical adaptation.

바이오 문서에서 지지 벡터 기계를 이용한 문법관계 분석

박경미(Kyung-Mi Park),황영숙(Young-Sook Hwang),임해창(Hae-Chang Rim) 한국정보과학회 언어공학연구회 2003 한국정보과학회 언어공학연구회 학술발표 논문집 Vol.2003 No.10