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RISS 인기검색어
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- 저자 : 노성훈(Sung Hun Noh) (검색결과 6 건)
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류창학(Chang Hak Yoo),노성훈(Sung Hun Noh),김용일(Yong Il Kim),서진학(Jin Hak Suh),민진식(Jin Sik Min),이경식(Kyong Sik Lee) 대한소화기학회 1998 대한소화기학회지 Vol.30 No.1
N/A Background/Aims: Prirnary gastric lymphoma is an uncommom tumor, constituting less than 5% of gastric malignancies. Optimal treatment of early-stage gastric lymphoma has been a matter of debate for several years. Our purpose in this study is to evaluate the exact role of surgery in the treatment of gastric lymphoma. Methods: Retrospective study of 63 patients, treated at the Dept. of Surgery, Yonsei Univ., College of Medicine from 1980 to 1994 was performed. Survival and multivariate analyses were done using the Kaplan-Meier method and Coxs proportional hazard model. Results: The mean age was 49.4 years, the ale to female ratio was 1.5:1 and the mean tumor size was 5.lcm in maximal diameter. The distribution of histologic grade according to the Working formulation was low-grade(n=24), intermediate-grade(n=32), high-grade(n=7) and high with low-grade(n=l). The distribution of stage according to the criteria of Musshoff was I(n=35), II-1(n=l 1), II-2(n=14), IV(n=3). Fifty two patients underwent gastric resection: subtotal(n=29), total (n=23) and the remaining 11 patients were diagnosed by laparotomy biopsy(n=4) and endoscopic biopsy(n=7) without gastric resection. Treatment modalities included surgery(S), chemotherapy (CT), and radiotherapy(RT) in the following proportions: only S(n=l9), S+CT(n=17), S+RT(n=4), S+CT+RT(n=12) and CT+RT(n=l 1). The overall 5-year survival rate was 72.5%. The 5-year survival rates according to stage were 87.3% in stage I, 76.2% in II-1, and 45.7% in II-2. No difference in survival rate was found according to treatrnent modality. Significant prognostic factors by univariate analysis were histologic grade, multifocality, lymph node metastasis, gastric resection and stage. Among them, independent prognostic factor by multivariate analysis was stage (p=0.0011). Conclusions: We suggested that surgical role in the treatment of early gastric lymphoma(stage I, II) may still be primary therapeutic procedure and the extent of sugical resection should be a standard radical gastrectomy with D2 or D2+a lymph node dissection. But in the intermediate or high grade tumor, multifocal lesions, LN metastasis and advanced stage, chemotherapy or radiotherapy should be considered as adjuvant therapy. (Korean J Gastroenterol 1997; 30:39 - 47)
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위암의 DNA 배수성과 휴지기 세포 분획의 임상 및 병리적 연관성
하현수(Hyun Su Hah),노성훈(Sung Hun Noh),이정운(Jung Woon Lee),민진식(Jin Sik Min) 대한소화기학회 1995 대한소화기학회지 Vol.27 No.5
N/A Background/Aims: Previous studies have shown that clinicopathological findings are correlated with the DNA ploidy and S-phase fraction analyzed by flow cytometry in malignant tumors such as breast and colorectal cancer. We studied the clinicopathological correlations of DNA ploidy and S-phase fraction in gastric carcinoma. Methods: DNA flow cytometry was performed using fresh tissue in 188 patients who underwent gastrectomy from Aug. 1993 to Feb. 1995. The DNA ploidy and S-phase fraction were correlated with various clinicopathological findings in a retrospective manner. Results: The incidence of DNA aneuploid was 31.9%. DNA aneuploidy was more frequently associated with male patients and with antral location(p=0.001 & p=0.04). Moderately differentiated adenocarcinoma had a significantly higher frequency of DNA aneuploid than the other histologic type(p=0.007). The overall mean of S-phase fraction was 10.0%, The mean for diploid group was 6.3 fo and that for aneuploid group 17.6%. Higher S-phase fraction(-- 11%) was associated with aneuploid, antral location, moderately differentiated adenocarcinoma, and the group with more than 4 metastatic lymph nodes. Conclusions: DNA aneuploidy and S-phase fraction of gastric carcinoma were significantly correlated with various clinicopathological findings. Further studies on correlations with 1ong-term results such as recurrence and survival rate will be required to establish DNA aneuploidy and S-phase fraction as a significant biological marker in gastric carcinoma. (Korean J Gastroenterol 1995;27: 536-545)
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실리콘 단결정 잉곳용 석영유리 도가니의 brownish ring에 대한 연구
정윤성,최재호,민경원,변영민,임원빈,노성훈,강남훈,김형준,Jung, YoonSung,Choi, Jae Ho,Min, Kyung Won,Byun, Young Min,Im, Won Bin,Noh, Sung-Hun,Kang, Nam-Hun,Kim, Hyeong-Jun 한국결정성장학회 2022 한국결정성장학회지 Vol.32 No.3
A brown ring (hereinafter referred to as BR) on the inner surface of a quartz glass crucible used in the manufacturing process of a silicon ingot for semiconductor wafers was studied. BR is 20~30 ㎛ in size and has an asymmetric brown ring shape. The size and distribution of BR were different depending on the crucible location, and the size and distribution of BR were the largest and most abundant in the round part with the highest crucible temperature during Si ingot growth. BR contains cristobalite, which has a higher coefficient of thermal expansion than quartz glass, so it is considered that surface cracks appear. The color development of BR and pin holes are presumed to be due to oxygen vacancies.
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강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),김원호(Won Ho Kim),홍성표(Sung Pyo Hong),노성훈(Sung Hun Noh),신동환(Dong Hwan Shin) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.2
Papillary cystic neoplasm of the pancreas is a rare low-grade malignant tumor which occurs chiefly in young women. It is also designated as a solid and papillary epithelial neoplasm of the pancreas because of its distinctive microscopic features, that is, papillary areas composed of layers of tall cells situated on fibrovascular stalks and solid areas consisting of sheets of cells with interspersed areas of cystic degeneration. Since the prognosis for this lesion is much more favorable than for any other pancreatic neoplasm due to its rare metastasis and recurrence rate, preoperative suspicion and correct diagnosis are important for this unusual and potentially curable tumor. We present a 22-year-old female patient with a papillary-cystic neoplasrn of the pancreas who complained of left upper quadrant abdominal pain. Ultrasonography demonstrated a large, partly cystic tumor in the pancreatic tail and abdominal cornputed tomography disclosed a well-defined solid and cystic mass. On celiac arteriography, the splenic artery and superior mensenteric artery were displaced by the tumor, and no tumor vessel was seen. ERCP showed displacement of the main pancreatic duct and absence of ductal branches in the mass area. The tumor was totally excised with the attached spl en and a small portion of the adherent distal pancreas on the 13th. Hospital day.
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