한국인 성생활(性生活) 특성(特性)에 대한 기초적(基礎的) 연구(硏究)

나종구,조봉춘,맹광호,최상진,김승조,Rha, J.G.,Cho, B.C.,Meng, K.H.,Choi, S.J.,Kim, S.J. 대한생식의학회 1978 Clinical and Experimental Reproductive Medicine Vol.5 No.1

The purpose of this study is to explore into the Korean Women's sexual life in terms of sexual behavior, sexual attitudes, and sexual experiences. In recent years, it has been generally recognized in both academic area and general publics that traditional norms, values, and patterns of behavior have been rapidly changing in Korea, thus being replaced by new ones. 1. The prevailing preconception that Korean women are sexwise traditional and conservative seems to be no longer true in the present days. 2. In this country, their sexual behaviors and attitudes at least within their marriage have been already westernized, being very similar to those of western women. 3. Knowledge and information of sexual matters held by Korean women prior to their marriage seems to be very limited, compared to those of western women. 4. It seems that Korean women have developed positive attitudes toward sex education practice in their family.

Premarin검사를 이용한 무월경환자에서의 시상하부-뇌하수체의 기능평가

이진우,나종구,Lee, J.W.,Rha, J.G. 대한생식의학회 1984 Clinical and Experimental Reproductive Medicine Vol.11 No.2

Hypothalamic-pituitary function in patients of 6 selected groups of amenorrhea was evaluated by performing premarin test. Selected amenorrheic patients were divided into 6 groups of Turner's syndrome(5), adrenogenital syndrome(3), Sheehan's syndrome(4), moderate hyperprolactinemia(3), severe hyperprolactinemia(9) and functional oligoamenorrhea(9) the diagnoses of which were performed according to modified our own protocol for management of amenorrheic patients. As control 20 normally cycling women in mid follicular phase determined by their symptothermal charts during last 6 months designed by WHO were compared. The premarin test which is one of the tests evaluating the hypothalamic-pituitary function by the principle of negative and positive feed back effect's of estrogen was performed by injecting 20 mg of premarin in volus intravenously. The levels of serum LH before, 24, 48, 72, 96 and 120 hours after injection of premarin were measured by double antibody technique radioimmunoassay the reagents of which were supplied by WHO. The results were as follows: 1. Both negative and positive feed back effects by exogenous estrogen were well preserved even in the patients of gonadal dysgenesis although the baseline levels were much higher than normal. 2. In the patients of Sheehan's syndrome one could observe the minimal response of feed back effect in the case with minimal pituitary function. 3, Androgens in adrenogenital syndrome and prolactin in hyperprolactinemia may suppress mainly the positive feed back effect rather than the negative one. The suppressive effect can be abolished by proper treatments which can eliminate those suppressive hormones. 4. This premarin test may be beneficial for predicting the result of clomiphene in ovulation induction.

자간전증의 생화학적 표지물질과 유용성

이종건(J. K. Lee),이형근(H. K. Lee),김용욱(Y. W. Kim),정대영(K. Y. Jung),이종승(C. S. Yi),김사진(S. J. Kim),나종구(J. G. Rha),김수평(S. P. Kim) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.12

Background and Puropse: The pathophysiologic features of preeclampsia are poorly understood. The diagnosis of preeclampsia is based not on the pathophysiology, but on the clinical symptoms. The endothelial dysfunction and the intravascular coagulopathy secondary to it, might be pivotal in the pathophysiology of preeclampsia. The purpose of this study is to investigate the significance of the potential biomarkers based on pathophysiology in preeclampsia. Methods: The vascular cell adhesion molecule-1 (VCAM-1), platelet-derived growth factor (PDGF-AB), antithrombin-III (AT-III) and D-dimer were measured in the plasma of the normotensive pregnant(control group) and preeclamptic women(study group). On the basis of the mean ±2SD or mean ±1SD cut-off value of biomarkers in control group, the sensitivity, specificity, positive predictive value and negative pred ctive value of each marker were calculated. Results: There were significant differences in VCAM-1, AT-III and D-dimer between control and study group. But the levels of PDGF were not significantly different from each other. With the mean±2SD cut-off value, the sensitivities of VCAM-1, AT-III and D-dimer were 38%, 34% and 40%, respectively. The specificities of VCAM-1, AT-III and D-dimer were 100%, 87% and 100%, respectively. Their positive predictive values were 100%, 86% and 100%, respectively. Their negative predictive values were 57%, 36% and 42%, respectively. With the mean ±1SD cut-off value, the sensitivities of VCAM-1, AT-III and D-dimer were 43% 51% and 60%,respectively Their specificities are 80%, 87% and 80%, respectively. Their positive predictive values were 64%, 90% and 88%, respectively. Their negative predictive values were 50%, 43% and 46%, respectively. Conclusion: The combination of these biomarkers such as VCAM-1, AT-III and D-dimer may be more useful as a biomarker in preeclampsia.

자연피임법으로서의 배란법의 피임효과

배석천,정윤조,나종구,오원섭,김승조,Bae, S.C.,Chung, Y.J.,Rha, J.G.,Oh, W.S.,Kim, S.J. 대한생식의학회 1976 Clinical and Experimental Reproductive Medicine Vol.3 No.1

In recent years, explosive increase in population has been damaging mankind in terms of deprivation of natural resources and more of economical demands. Therefore, we have thought about problems as to counter-balance the increasing population, and reached a resolution of artificial methods of controlling birth. In the past, though now used in some of contraceptive methods, extravaginal ejaculation, condom were commonly used. But recently, pills, IUD and several kinds of operative procedures are quite popular. Though the recent methods are known to be effective compared with the traditional methods, a certain unwanted side effects as well as limited value of usages now must be discussed. On this aspect, we are trying to research for a ideal methods such as symptom free, more of natural way of family planning and try to zero the failure rate. And also it has been suggested that only if those scientific methods of controlling birth can be base on religious concepts of moral being, it will be enlightened. At the Happy Family Planning Clinic of St. Mary's Hospital, we apply Billing's ovulation method to out-patients who want contraception and usually advise them to use it on a self-care basis. For a retrospective study of the presurvey data analysis and use-effectiveness of the ovulation method from April 1, 1975 to Nov., 30, 1975, we have dealt with a total of 1,383 women (urban areas 465, rural areas 918). The results of preliminary survey were as follows; 1) Among 465 women in Seoul areas, the failure rate was 10.3, which signified unplanned pregnancies of 32 women. 27 of the 32 women were pregnant due to the users own failure and the remaing 5 due to the failure of the method. Therefore, the failure of the method accounted for 1.6. 2) Among 918 women in rural areas, the failure rate was 15.2 signifing unplanned pregnancies in 93 women. The cause of the failure in 81 of the 93 women was attributable to the user's own mistake and that in the remaing 12 to the default of the method. Therefore, the failure attributable to the method accounted for 2.0.

산부인과 영역에 있어서 Amoxicillin의 임상효과

김수평,허필형,나종구 中央醫學社 1977 中央醫學 Vol.32 No.3

Thirty-two patients admitted to Dept. of Obstet. & Gynec., St. Mary's Hospital of Catholic Medical College were treated with amoxicillin for infections, proved on culture and prophylactic use. The antibiotic was administered orally in 2 capsules of 250mg two-times a day for 5 to 14 days. Thirty out of 32 patients were cleared of infection and these were determined by clinical signs, symptoms and organism culture on those can be available. Two cases, infected by Pseudomonas and unknown organism, among 32 patients showed poor effects to amoxicillin therapy. Amoxicillin was well tolerated by all patients without serious complications. Side effects were minimal and that disappeared within 24 hours even on continuation of the therapy. No other abnormal findings on CBC, urinalysis and blood chemistry were observed.

Candida성 질염에서 Fermalac^(�) 질정의 치료효과

강병철,김창이,나종구 최신의학사 1985 最新醫學 Vol.28 No.2