충남 일부 중년 성인의 운동습관에 따른 식습관 및 스트레스 상태

김세윤,서연자,김미현,최미경,Kim, Se-Yune,Seo, Yeon-Ja,Kim, Mi-Hyun,Choi, Mi-Kyeong 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.1

This study aimed to evaluate the health concern, eating habits, dietary behavior, and psychological stress among middle-aged adults in Chungnam according to their exercise status. A total of 437 adults with a mean age of 42.6 years participated in this study and completed a questionnaire survey. The subjects were divided into one of three groups according to their exercise status: never doing exercise (NDE; n=144), doing exercise once a week (DEO; n=186), and doing exercise twice a week or more (DET; n=107). Results demonstrated significant differences in concern about health, subjective health status, meal regularity, dietary problems, and stress score among the three groups. The DET and DEO groups were more concerned about their health (p<0.001), and had a perception that their health status was better than that of the NDE group (p<0.01). A larger percentage of the DET group had breakfast everyday (p<0.05) and a smaller percentage of the DET group had dietary problems such as irregular mealtime and skipping meals (p<0.01), compared to the other groups. The average stress score of the DET group was significantly lower than that of the DEO and NDE groups (p<0.05). The results reveal that doing regular exercising at least twice a week is associated with higher health concern, more desirable dietary habits, and lower psychological stress in middle-aged adults. These findings support the beneficial effects of regular exercise for health, dietary habits, and stress control.

간경변 환자에서 CTP, MELD, MELD-Na 점수의 단기 사망률 예측에 대한 비교 분석

김세윤 ( Se Yune Kim ),임형준 ( Hyung Joon Yim ),이준영 ( June Young Lee ),이범재 ( Beom Jae Lee ),김동일 ( Dong Il Kim ),정성우 ( Sung Woo Jung ),한우식 ( Woo Sik Han ),이종섭 ( Jong Sup Lee ),구자설 ( Ja Seol Koo ),서연석 ( Yeon 대한소화기학회 2007 대한소화기학회지 Vol.50 No.2

목적: MELD (model for end-stage liver disease)는 간이식 대상자의 우선 순위를 정하는 기준으로 상용되며, 말기 간질환 환자의 예후 판정에 유용한 지표이다. 최근 MELD 점수에 혈중 나트륨(Na) 수준을 반영한 MELD-Na이 MELD보이 단기 사망률을 예측하는 데 보다 유용할 것이라는 의견이 제시되었다. 그러나 아직 국내 환자를 대상으로 한 MELD-Na의 유용성 평가 자료는 없다. 따라서 이번 연구에 서는 간경변 환자들을 대상으로 Child-Turcotte-Pugh (CTP), MELD, MELD-Na 세 가지 점수의 사망률 예측에 대해 비교 분석하여 MELD-Na이 타 지표보다 단기 사망을 예측하는데 보다 유용한 것인가를 판정하고자 하였다. 대상 및 방법: 1996년 1월부터 2006년 9월까지 고려대학교 안산병원 소화기내과에 입원하였던 355명의 간경변증 환자를 대상으로 후향 분석하였다. 간암, 만성 신부전, 중증 심폐질환자, 악성 종양이 있는 경우는 제외하였다. 입원 당시 각 점수에 따른 누적 생존율은 Kaplan-Meier 생존함수를 이용하여 구하였고 log rank test로 생존기간의 차이를 검증하였다. 또한 AUC를 이용해 3개월, 그리고 1년 사망률에 대한 위의 세가지 점수의 예측능을 비교 분석하였다. 결과: 세 가지 지표 모두가 점수에 따른 누적 생존율의 차이가 유의하였다(p<0.001). 3개월 단기 사망을 예측하는 데 있어 각 지표의 AUC는 CTP 0.828, MELD 0.845, MELD-Na 0.862 (p>0.05)이었으며 1년 내 사망에 대한 각 지표의 AUC는 각각 0.792, 0.800, 0.831(p>0.05)로 유의성은 없었으나 MELD-Na이 가장 높은 경향을 보였다. 다변량 분석에서는 세 가지 지표 중 MELD-Na만이 3개월 사망과 유의한 관련성이 있었다. 결론: 국내 간경변 환자를 대상으로 분석한 세 가지 예후 평가 점수 체계 중 MELD-Na은 우수한 단기 사망 예측능을 보였다. 아직 좀 더 많은 환자를 대상으로 한 대규모의 연구가 필요할 것으로 생각하나 만성 간질환 환자에서 단기 사망과 예후에 대한 지표로서 MELD-Na을 우선적으로 사용할 것을 고려해 볼 수 있다. Background/Aims: MELD-Na (model for end-stage liver disease with incorporation of serum sodium) was suggested to provide better survival prediction than MELD alone for patients with end stage liver disease. However, there is no data verifying the usefulness of MELD-Na for predicting short term mortality of cirrhotic patients in Korea. This study was aimed to determine whether MELD-Na would be more accurate in predicting short term mortality than other scoring systems such as Child-Turcotte-Pugh (CTP) or MELD. Methods: Data from 355 patients admitted due to liver cirrhosis were retrospectively reviewed. The cumulative survival rates were obtained. Prediction of mortality rate for three months and one year were analyzed using the area under the receiver`s operating characteristics curve (AUC). Results: One hundred patients (28%) died during the study period. All of the three systems showed significant differences in the cumulative survival rate according to the scores on admission (p<0.001). The AUC of CTP, MELD, and MELD-Na in predicting three-months mortality were 0.828, 0.845, and 0.862 (p>0.05), and the AUC of each score system for death within one year were 0.792, 0.800, and 0.831, respectively (p>0.05). The AUC of MELD-Na in predicting short term death were the highest, although it was not statistically significant. Multivariate analysis showed that only MELD-Na was significantly related to three-month mortality (p=0.012). Conclusions: MELD-Na is more appropriate in predicting short term mortality, but larger scale studies are needed to confirm the superiority of MELD-Na to MELD and CTP in patients with liver cirrhosis. (Korean J Gastroenterol 2007;50:92-100)

충남지역 초등학생의 총당류 섭취와 영양밀도 및 비만도와의 관련성

김세윤(Se-Yune Kim),김미현(Mi-Hyun Kim),강명화(Myung-Hwa Kang),최미경(Mi-Kyeong Choi) 동아시아식생활학회 2017 동아시아식생활학회지 Vol.27 No.2

The purpose of this study was to evaluate total sugars intake and determine its relationship with nutrient density and obesity degree in elementary school children. A total of 1,292 elementary school students (638 boys, 654 girls) in Chungnam participated in this study. Daily total sugars intake of subjects was analyzed using the USDA database of sugars after a questionnaire survey using 24-hour recalls. The average age of subjects was 9.7 years, daily energy intake was 1,834.0 kcal, and total sugars intake was 37.6 g/day, which was 8.3% of total energy intake. Sugars intake from the milk group was highest at 18.4 g/day, followed by fruits, cereals, sugars and sweeteners, and beverages. Nutrient density of protein as well as Na, Fe, and Zn levels were significantly lower according to total sugars intake level. There was no significant difference between overweight and obesity risk among the sugars intake quartile groups. In conclusion, total sugars intake of subjects was not significantly high and not associated with obesity risk; however, high sugars intake in children was associated with decreased consumption of protein, Fe, and Zn, which are important for growth.

충남 일부지역 아토피 피부염 초등학생의 식습관과 영양소 섭취 실태 조사

김은진(Eun-Jin Kim),김현진(Hyun-Jin Kim),김세윤(Se-Yune Kim),김이영(Yi-Yeong Kim),이해지(Hae-Ji Lee),강명화(Myung-Hwa Kang),최미경(Mi-Kyeong Choi) 동아시아식생활학회 2014 동아시아식생활학회지 Vol.24 No.3

The purpose of this study was to investigate the dietary behaviors, eating habits, and nutrient intakes of elementary students with atopic dermatitis. Dietary conditions during infancy, dietary regularity, dietary behaviors, eating habits, and daily nutrient intakes were surveyed and compared between children with (WAD) and without (WOAD) atopic dermatitis using the 24-hr recall method. The ratio of children who responded ‘I eat regular meals’ was significantly lower in the WAD compared to WOAD group (76.4% vs. 81.7%, p<0.05). The ratio of children who answered ‘I eat processed foods or fast foods more than once a week’ (p<0.01) and ‘I take nutritional supplements’ (p<0.001) was significantly higher in the WAD compared to WOAD group. The scores for ‘I eat milk and its products everyday’ (1.4 vs. 1.5, p<0.05), ‘I eat dishes fried or stirred with oil more than twice a week’ (2.0 vs. 2.1, p<0.05), and ‘I eat snacks such as ice cream, cake, snacks, carbonated beverages more than twice a week’ (1.9 vs. 2.0, p<0.05) were significantly lower in the WAD group than in the WOAD group. Daily energy intakes were 1,859.1 kcal and 1,829.5 kcal in WAD and WOAD children, respectively, with no significant difference. However, daily intakes of fat (p<0.05), phosphorus (p<0.05), and vitamin B2 (p<0.05) in WAD children were significantly higher than in WOAD children. To sum up, elementary students with atopic dermatitis had irregular eating habits and higher intake frequency of processed or fast foods, milk and its products, dishes fried or stirred with oil, and snacks compared to normal children. Dietary guidance and nutritional education are required to improve irregular eating habits and induce adequate nutrient intakes in children with atopic dermatitis.

샘암종과 소세포암종이 혼재하는 원발 위암에서 소세포암종만이 간전이를 일으킨 1예

장진수 ( Jin Su Jang ),임형준 ( Hyung Joon Yim ),이범재 ( Beom Jae Lee ),김세윤 ( Se Yune Kim ),김동일 ( Dong Il Kim ),이홍식 ( Hong Sik Lee ),이상우 ( Sang Woo Lee ),최재현 ( Jai Hyun Choi ) 대한소화기학회 2007 대한소화기학회지 Vol.50 No.3

Primary small cell carcinoma (SCC) of stomach is a rare and highly aggressive malignancy with extremely poor prognosis. We report a 71-year-old man with upper abdominal pain diagnosed as single hepatic metastasis of SCC from mixed SCC and adenocarcinoma of the stomach. An endoscopic examination showed the presence of Borrmann type 2 gastric cancer, 2 cm in size on the lesser curvature of antrum. An abdominal CT scan revealed a huge dumbbell shaped mass with peripheral arterial enhancement and central low density in left lobe of the liver. Endoscopic biopsies showed solid proliferation of small, monotonous tumor cells with hyperchromatic nuclei and scanty cytoplasm. The neoplastic cells were positive for immunostaining with anti-chromogranin and anti-synaptophysin. There were also other neoplastic cells with gland formation being positive for anti- cytokeratin. On the basis of these findings, we made a final diagnosis of mixed SCC and adenocarcinoma of the stomach. In addition, we also confirmed hepatic metastasis of SCC through the microscopic finding and immunostaining of tissues of liver mass. Conclusively, we report a case of hepatic metastasis of SCC only from mixed SCC adenocarcinoma of the stomach. (Korean J Gastroenterol 2007;50:193-198)

프로톤 펌프 억제제 종류에 따른 Helicobacter pylori 제균 효과 비교 - Omeprazole, Rabeprazole, Esomeprazole, Lansoprazole -

금보라 ( Bo Ra Keum ),이상우 ( Sang Woo Lee ),김세윤 ( Se Yune Kim ),김민정 ( Min Jeong Kim ),정록선 ( Rok Son Choung ),임형준 ( Hyung Joon Yim ),진윤태 ( Yoon Tae Jeen ),이홍식 ( Hong Sik Lee ),전훈재 ( Hoon Jai Chun ),엄순호 ( S 대한소화기학회 2005 대한소화기학회지 Vol.46 No.6