해외건축동향: 독일 - 애니메이션 어린왕자와 야수주의

김성환,Kim, Sung-hwan 대한건축사협회 2016 建築士 Vol.2016 No.1

인체 혈구암세포에 대한 단선탕(丹仙湯) 추출물의 증식억제 및 세포사멸 유도에 관한 연구

김성환,박상은,홍상훈,Kim, Seong-Hwan,Park, Sang-Eun,Hong, Sang-Hoon 대한한방내과학회 2011 大韓韓方內科學會誌 Vol.32 No.4

Objectives : This study investigated the biochemical mechanisms of anti-proliferative and pro-apoptotic effects of the water extract of Dan-Seon-Tang (DST) in human leukemia U937 cells. Methods : U937 cells were exposed to DST and growth inhibition was measured by MTT assay. Results : Exposure of U937 cells to DST resulted in the growth inhibition in a concentration-dependent manner. This inhibitory effect was associated with morphological changes and apoptotic cell death such as formation of apoptotic bodies, increased populations of apoptotic-sub G1 phase and induction of DNA fragmentation. The induction of apoptotic cell death in U937 cells by DST was associated with up-regulation of death receptor 4 (DR4) and down-regulation of Bid, surviving and cellular inhibition of apoptosis protein-2 (cIAP-2) expression. DST treatment also induced the proteolytic activation of caspase-3, caspase-8 and caspase-9, and a concomitant degradation of caspase-3 substrate proteins such as poly (ADP-ribose) polymerase (PARP), phospholipase (PLC)-${\gamma}1$, ${\beta}$-catenin and DNA fragmentation factor 45/inhibotor of caspase activated DNAse (DFF45/ICAD). Furthermore, apoptotic cell death by DST was significantly inhibited by caspase-3 specific inhibitor z-DEVD-fmk, demonstrating the important role of caspase-3. Conclusions : These findings suggest that herb prescription DST may be a potential chemotherapeutic agent for the control of human leukemia U937 cells; further study is needed to identify the active compounds.

Interferon과 Ribavirin 병용요법 시행중인 만성 C형간염 환자에서 발생한 부작용에 대한 침구치료 증례

김성환,홍상훈,박동일,Kim, Sung-hwan,Hong, Sang-hoon,Park, Dong-il 대한침구의학회 2003 대한침구의학회지 Vol.20 No.1

Objective : Interferon-alpha and Rivabirin are much used at the same time to treat Chronical C viral hepatitis. But interferon caused lots of unexpected side effects, Acupuncture Treatment for them will be an alternative plan. Methods : We first posed questions to a 4 year-old man who ha skin flare, fatigue, itching, insomnia, pronounced a diagnosis based on overall of symptoms and signs and then treated Acupuncture, Moxibustion and Electroacupuncture. We acupunctured a BL17, BL18, BL20 and removed it at once. We electroacupunctured at GV20, Yin tang(Ex-HN3) form 20 minutes, acupunctured at Bi yi(鼻翼, Extra-point), S36, P6. Pizhengge(脾定格) was acupunctured for 10 minutes. Results : The symptoms of fatigue, insomnia, itching are reduced after acupuncture treatments and they made a person keep interferon treatment on. Conclusions : We confirmed that acupuncture treatments make a patient of chronic C viral hepatitis reduce and improve side effects of interferon treatment. We should keep on studying the various and efficient method of acupuncture treatment to improve living quality and treatment efficiency of patients.

해외건축동향: 독일 - 보이지 않는 손 ; 건축과 문화 콘텐츠의 협업 가능성에 대하여

김성환,Kim, Sung-hwan 대한건축사협회 2015 建築士 Vol.2015 No.1

IHF 총회-IHF 총회 및 학술대회 소개

김성환,Kim Sung-Hwan 대한병원협회 2007 대한병원협회지 Vol.36 No.5

개인용 컴퓨터에 의한 방사선기술학 논문의 검색 및 데이터베이스 구축에 관한 고찰

김성환,Kim, Sung-Hwan 대한방사선기술학회 1997 방사선기술과학 Vol.20 No.1

Although many useful arfticles appear in the journals published in Korea, they are not always cited by researchers mainly due to absence of efficient searching system. The author made a program with 4 predefined filtering forms to detect published articles rapidly and accurately. The program was coded using database management system CA-Clipper VER 5.2. I used 486DX-II (8 Mbyte Ram, VGA, 560 Mbyte Hard Disk), desk-jet printer(HP-560k), and MS-DOS VER 5.0. I inputed twenty articles in the journal of Korean Society Radiotechnological Technology. And this program test for retrive article and made database.

의암호 퇴적물 내 인공방사성동위원소 (¹³⁴Cs, ¹³⁷Cs, ^239+240Pu) 분포특성 연구

김성환,이상한,오정석,최종기,강태구,Kim, Seung Hwan,Lee, Sang-Han,Oh, Jung Suk,Choi, Jong Ki,Kang, Tae Gu 대한방사선방어학회 2015 방사선방어학회지 Vol.40 No.4

공공수역 내 방사성물질 분포특성 파악을 위하여 춘천시 의암호 퇴적물 내 인공방사성핵종인 $^{134}Cs$, $^{137}Cs$, $^{239+240}Pu$과 자연방사성동위원소인 $^{210}Pb$을 분석하였고, 퇴적물 내 유기물의 특성을 파악하기 위하여 총 유기탄소(total organic carbon, TOC)를 분석하였다. 의암호 퇴적물 내 $^{134}Cs$ 농도는 4지점 모두 minimum detectable activity(MDA) 미만으로 나타났으며, $^{137}Cs$ 농도는 $MDA{\sim}8.79Bq{\cdot}kg^{-1}-dry$으로 나타났다. 표층 내 $^{137}Cs$의 농도는 $2.4{\sim}4.2Bq{\cdot}kg^{-1}-dry$의 범위를 나타냈고, St. 4에서 최소값, St. 3에서 최대값을 보였다. 의암호 퇴적물 내 $^{239+240}Pu$ 농도는 $0.049{\sim}0.47Bq{\cdot}kg^{-1}-dry$의 농도를 보였고, St. 2에서 최소값이, St. 3에서 최대값이 나타났다. $^{239+240}Pu$과 $^{137}Cs$ 농도의 상관관계 (r)는 0.54~0.97로 이들 두 핵종의 퇴적물 내 거동과 기원이 유사한 것으로 사료된다. $^{134}Cs$의 농도가 MDA 미만으로 검출된 점과 $^{239+240}Pu/^{137}Cs$의 평균값 0.041이 과거 대기 핵실험기원의 농도 비와 비슷한 값이 나타나는 점으로 의암호 퇴적물 내 인공방사성동위원소 ($^{134}Cs$, $^{137}Cs$, $^{239+240}Pu$)의 기원은 후쿠시마 사고가 아닌 과거 핵실험에 인한 낙진의 영향으로 사료된다. 의암호 퇴적물 내 $^{210}Pb$의 결과를 이용하여 퇴적물의 퇴적률을 산출한 결과, St. 2에서 $0.31{\pm}0.06cm{\cdot}y^{-1}$의 퇴적률을 나타냈으며, 이는 $^{137}Cs$의 퇴적물 내 peak를 1963년으로 가정하였을 때 측정된 퇴적률, $0.41{\pm}0.05cm{\cdot}y^{-1}$와 불확도($2{\sigma}$)의 범위에서 유사한 값으로 나타내었다. 의암호 퇴적물 내 TOC는 0.20~13.01%의 값이 나타났으며, 퇴적물 내 TOC와 $^{137}Cs$의 상관관계는 St. 1에서 다른 지점에 비해 높게 나타났다. The objective of this study is to identify the radionuclide distribution in public water by carrying out the analysis of artificial radionuclides($^{134}Cs$, $^{137}Cs$, $^{239+240}Pu$), natural radionuclide($^{210}Pb$) and TOC in the lake Euiam sediment in Chuncheon, South Korea. The $^{134}Cs$ concentration in all lake sediments showed below MDA values, and the $^{137}Cs$ concentration in lake sediment were ranged from MDA to $8.79Bq{\cdot}kg^{-1}-dry$. The $^{137}Cs$ concentrations in surface sediment were reported to be 2.4 to $4.2Bq{\cdot}kg^{-1}-dry$. The lowest concentration of $^{137}Cs$ was reported at St. 4 and the highest concentration was reported at St. 3, respectively. The $^{239+240}Pu$ concentration in lake sediment were ranged from 0.049 to $0.47Bq{\cdot}kg^{-1}-dry$. The lowest concentration was reported at St. 2 and the highest concentration was reported at St. 3. The correlation(r) between the $^{239+240}Pu$ concentration and $^{137}Cs$ concentration in lake sediment presented higher values (0.54 to 0.97) and this suggests the behavior and origin of $^{137}Cs$ is identical to the $^{239+240}Pu$ in the sediment. The $^{134}Cs$ concentration below MDA value and the $^{239+240}Pu/^{137}Cs$ ratio(mean value of 0.041) indicated that the artificial radionuclides in the sediment were originated from global fallout by the atmospheric testing of nuclear weapons conducted by former USSR and U.S.A, but not from the Fukushima Daiichi NPP accident. The sedimentation rate derived from $^{210}Pb$ age-dating method at St. 2 is calculated to be $0.31{\pm}0.06cm{\cdot}y^{-1}$. This value is similar to the value ($0.41{\pm}0.05cm{\cdot}y^{-1}$) estimated from the $^{137}Cs$ maximum peak produced from early 1960's. The content of TOC in lake Euiam sediments varied from 0.20 to 13.01%. While the highest correlation between TOC and $^{137}Cs$ concentration in the sediment were found at St. 1, the others presented the low correlation.

체크 노드 분할에 의한 LDPC 부호의 새로운 메시지 전달 복호 알고리즘

김성환,장민호,노종선,홍송남,신동준,Kim Sung-Hwan,Jang Min-Ho,No Jong-Seon,Hong Song-Nam,Shin Dong-Joon 한국통신학회 2006 韓國通信學會論文誌 Vol.31 No.4c

본 논문에서는 체크 노드 분할에 의한 low-density parity-check(LDPC) 부호의 새로운 직렬 메시지 전달 복호 알고리즘을 제안한다. 이 새로운 복호 알고리즘은 특히 적은 반복 횟수에 대하여 기존의 메시지 전달 복호 알고리즘의 비트 오율(BER) 성능보다 더 우수한 성능을 보인다. 체크 노드의 분할된 부분 집합의 개수가 증가함에 따라 비트 오율 성능이 보다 좋아진다는 사실을 분석적 결과로 확인할 수 있다. 또한 가우시안 근사화를 이용한 밀도 진화를 이용하여 변수 노드에서 메시지들의 평균값에 대한 재귀 방정식을 유도하고, 모의 실험을 이용하여 분석적인 결과를 검증하였다. In this paper, we propose a new sequential message-passing decoding algorithm of low-density parity-check (LDPC) codes by partitioning check nodes. This new decoding algorithm shows better bit error rate(BER) performance than that of the conventional message-passing decoding algorithm, especially for small number of iterations. Analytical results tell us that as the number of partitioned subsets of check nodes increases, the BER performance becomes better. We also derive the recursive equations for mean values of messages at variable nodes by using density evolution with Gaussian approximation. Simulation results also confirm the analytical results.

수산화아파타이트/알루미나 복합체의 기계적 특성에 미치는 불화물 첨가제의 영향

김성환,방희곤,박상엽,Kim, Sung-Hwan,Bang, Hee-Gon,Park, Sang-Yeup 한국세라믹학회 2006 한국세라믹학회지 Vol.43 No.1

Hydroxyapatite $(HAp,\;Ca_{10}(PO_4)_6(OH)_2)$/alumina composites were fabricated with the addition of fluorides, such as $MgF_2$ and $CaF_2$. In this study, the effect of fluorides on the inhibition of phase decomposition and the mechanical properties of HAp was investigated. Due to the higher solubility of F ion in HAp structure, $MgF_2$ additive was more effective compared to $CaF_2$ additive in the lowering decomposition temperature of HAp. Therefore, the dissociation tendency of HAp was fully inhibited below $1400^{\circ}C$. The mechanical properties of HAp composites with $MgF_2$ additive showed higher value (flexural strength: $\~170MPa$, Vickers hardness: $\~7\;GPa$, fracture toughness: $\~1.5\;MPam^{1/2}$) compared to $MgF_2-free$ composites. The linear thermal expansion coefficient of HAp composites with $MgF_2$ showed the value of $16.4\times10^{-6}/^{\circ}C\;at\;20\~400^{\circ}C $.

해외건축동향: 독일 - 얀겔_걷는 도시를 만들어내는 건축사

김성환,Kim, Sung-hwan 대한건축사협회 2015 建築士 Vol.2015 No.2