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김봉희,Kim, Bohng-Hee 대한세포병리학회 2006 대한세포병리학회지 Vol.17 No.2
Villoglandular adenocarcinoma of uterine cervix has recently been described, and is characterized by good prognosis and occurrence in young women, except a small number of cases. Morphologically, it exclusively shows villoglandular growth and mild to moderate nuclear atypia, the cytologic diagnoses have been frequently missed due to interpretation error. We report here on the cytologic findings of two cases, and both cases were not diagnosed as adenocarcinoma before punch biopsy. One of these cases showed previously described characteristic features such as high cellularity and large tissue fragments with long villous fronds lined by columnar cell with mild nuclear atypia. The other showed moderate cellularity of somewhat smaller clusters without long villous structures. The clusters showed marked nuclear overlapping and the nuclei showed distinct moderate atypia with hyperchromasia and coarse chromatin pattern. The nucleoli were indistinct. Recognition of these features will be helpful to avoid underdiagnosis as a benign lesion, although diagnosis is still difficult in a portion of the cases.
$H\"{u}rthle$ 세포선종의 세침흡인 세포학적 소견 - 1예 보고 -
김봉희,강명숙,박재훈,김윤화,박용구,이주희,양문호,Kim, Bohng-Hee,Kang, Myoung-Suk,Park, Jae-Hoon,Kim, Youn-Wha,Park, Yong-Ku,Lee, Ju-Hie,Yang, Moon-Ho 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.2
The increased use of thyroid fine needle aspiration(FNA) has re-focused on $H\"{u}rthle$ cell lesions. The cytologic diagnosis of $H\"{u}rthle$ cell tumor is a challenge due to the presence of $H\"{u}rthle$ cells in non-neoplastic lesions and the inability to differentiate between benign and malignant $H\"{u}rthle$ cell tumor. We report a case of $H\"{u}rthle$ cell adenoma(HCA) un a 68-year old woman, with review of the cytopathologic findings. FNA revealed loosely cohesive or sheets of large oval to polygonal $H\"{u}rthle$ cells containing abundant granular cytoplasm. The hustopathologic examination confirmed the diagnosis of HCA with follicular growth pattern. Ultrastructurally, the cytoplasm was packed with variable sized mitochondria.
김봉희,공경엽,Kim, Bohng-Hee,Gong, Gyung-Yub 대한세포병리학회 2002 대한세포병리학회지 Vol.13 No.2
To determine the usefulness on fine needle aspiration cytology(FNAC) of bone lesions and the complementary role of FNAC and percutaneous needle biopsy, 75 cases of FNAC taken from bone lesions were analyzed. Correlations with histopathology were possible in 47 cases, including 14 cases of simultaneous core biopsy and 33 cases of subsequent open biopsy due to inadequate aspirates. Among 75 cases, 4 cases were benign tumors and tumor-like lesion, 11 cases were malignant primary bone tumors, 17 cases were metastatic tumors, and 43 cases were nonneoplastic bone lesions. The aspirates were adequate in 35 cases(46.7%), in all of which the discrimination between benignancy and malignancy was possible. The main reason for Inadequate aspirates was due to hypocellularity. In the cases of aspiration and core biopsy simultaneously done, the diagnostic accuracy of aspiration, core biopsy, and both were 57%(8/14), 78.6%(11/14), and 92.9%(13/14), respectively. We conclude that a final diagnosis based on cytology is possible with the adequate aspirates and the clinical and radiological findings. Also we confirm the complementary role between FNAC and core biopsy in bone lesions.
질에서 발생한 악성 흑색종의 Papanicolaou 도말의 세포학적 소견 - 1례 보고 -
강명숙,김봉희,박재훈,김윤화,박용구,이주희,양문호,Kang, Myung-Suk,Kim, Bohng-Hee,Park, Jae-Hoon,Kim, Youn-Wha,Park, Yong-Koo,Lee, Ju-Hie,Yang, Moon-Ho 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.2
Primary malignant melanoma of vagina is a rare tumor which is easily misinterpretated in routine cytologic examination. We lately experienced a case of primary malignant melanoma of the vagina with direct cervical extension diagnosed by Pap smear. The cervicovaginal smear showed variable sized clusters of epithelial cells or singly scattered abnormal epithelial cells. Most of the tumor cells had round hyperchromatic nuclei with prominent nucleoli and brownish pigments in cytoplasm. The cytologic findings are compared with histologic features of resected specimen.
유방의 양성 및 악성 유두상 종양의 세포학적 소견의 비교 검색
이호정,공경엽,김봉희,안세현,박정미,허주령,강신광,노재윤,Lee, Ho-Jung,Gong, Gyung-Yub,Kim, Bohng-Hee,Ahn, Sei-Hyun,Park, Jeoug-Mi,Huh, Joo-Ryung,Khang, Shin-Kwang,Ro, Jae-Y. 대한세포병리학회 1999 대한세포병리학회지 Vol.10 No.1
Benign and malignant papillary neoplasms of the breast may be difficult to distinguish in both cytologic and histologic preparations. To define the cytologic features of benign and malignant papillary lesions, we retrospectively reviewed 18 cases of fine needle aspirates from histologically confirmed cases of papilloma or papillary carcinoma of the breast. This study included 3 intraductal papillary carcinomas, 3 invasive papillary carcinomas, and 12 intraductal papillomas. Ail cases were evaluated for presence or absence of papillary fragments, bloody background, apocrine metaplasia, macrophages, and degree of cellularity, atypia, and single isolated columnar epithelial cells. Papillary fragments were present in all cases. The background of the smear was bloody in all 6 carcinomas, but in only 7 out of 12 papillomas. Markedly increased cellularity was present in 4 carcinomas(67%) and 7 papillomas(58%). Single cells were present in 5 carcinomas(83%) and 8 papillomas(67%). The majority of papillomas and papillary carcinomas had mild to moderate atypia, and severe atypia was noted in one case of intraductal papillary carcinoma and one case of invasive papillary carcinoma. Apocrine metaplasia was absent in all cases of papillary carcinomas, but present in 8 papillomas(57%). Macrophages were noted in 4 carcinomas and were present in all cases of papillomas. The constellation of severe atypia, bloody background, absence of apocrine metaplasia and/or macrophages were features to favor carcinoma. Malignant lesions tended to show higher cellularity and more single isolated cells. The cytologic features mentioned above would be helpful to distinguish benign from malignant papillary lesions of the breast. However, because of overlapping of cytologic features, surgical excision should be warranted in all cases on papillary lesions of the breast to further characterize the tumor.
외음부 전정염 증후군 환자 30예의 임상병리적 특성 및 치료에 관한 고찰
정민형 ( Min Hyung Chung ),박정훈 ( Jung Hun Park ),김낙인 ( Nack In Kim ),김봉희 ( Bohng Hee Kim ),이주희 ( Juhie Hee Lee ),허주엽 ( Chu Yeop Huh ) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.12
목적 : 본 연구는 부인과 영역에서 흔히 접할 수 있는 vulvodynia의 일종으로 신체적, 정신적 장애를 일으킬 수 있고 성기능 장애 및 일상 생활의 장애를 유발할 수도 있으나 아직 그 원인과 치료 방법이 명확히 규명되지 않았고 널리 알려져 있지도 않는 vulvar vestibulitis syndrome에 대하여 그 임상병리학적 특징 및 치료법에 대해 고찰하여 소개하며 외래에서 부인과적 환자 진찰시 쉽게 간과되기 쉬운 vulvar vestibulit Objective : This study was performed to evaluate and introduce the clinicopathologic characteristics and treatment modalities of vulvar vestibulitis, a subset of vulvodynia, may cause physical disabilities, phycological or emotional distress, sexual dysfu
노동규(Dong Kyu Noh),서상기(Sang Gi Seo),정민형(Min Hyung Chung),이보연(Bo Yon Lee),김봉희(Bohng Hee Kim),김승보(Seung Bo Kim) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.8
The incidence of ectopic pregnancy has been increasing for many years and ectopic pregnancy is still a leading cause of maternal death although its mortality is reduced significantly with improved early diagnosis and treatment. Intraligamentous pregnancy, a subset of ectopic pregnancy, is one of the most unusual accident so that the diagnosis of intralgamentous pregnancy is hardly ever made prior to laparotomy. We experienced intraligamentous pregnancy with hemoperitoneum. So we presented a case with brief review of literature.