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경부 2, 3번 피부절을 침범한 Ramsay-Hunt 증후군 1례
이정석,최용석,송은향,김정미,한정호,김두응,Lee, Chung Seok,Choi, Yong Seok,Song, Eun Hyang,Kim, Jeung Mee,Han, Jeong Ho,Kim, Doo Eung 대한임상신경생리학회 2002 Annals of Clinical Neurophysiology Vol.4 No.1
Ramsay-Hunt syndrome is a viral disease associated with peripheral facial nerve paralysis accompany by erythematous vesicular rashs on the ear(zoster oticus) or in the mouth. Based on clinical presentations that indicated involvement of more than one ganglion, the gasserian, geniculate, petrous, accessory, jugular and second and third dorsal root ganglia comprised a chain in which inflammation of a single ganglion could extend to nearby ganglia. A 71-year-old man presented with left. peripheral facial palsy with otalgia, vesicular eruption in $V_2$, $V_3$, C2, C3 dermatome, tinnitus, and hearing loss.
김동현,박종현,권오상,김두응 중앙대학교 의과대학 의과학연구소 1997 中央醫大誌 Vol.22 No.2
Since the development of magnetic stimulation as a way of assessing the function of central motor pathways, various neurologic diseases have been investigated by motor evoked potentials(MEP). This study was carried out to evaluate the usefulness of clinical application of MEP to the stroke patients. MEP were elicited with transcranial cortical stimulation using a magnetic coil in 21 healthy subjects and 18 stroke patients. Average of age was 37.5±18.0 and 63.7±7.7 years in normal and patient groups respectively. All stroke patients had a mild to severe clinical unilateral motor weakness, and also were proven to have unilateral infarction or hemorrhage at various regions of brain radiologically. During MEP studies, neither significant side effects nor pin were encountered. MEP latency of abductor pollicis brevis(APB) and extensor digitorum brevis(EDB) in controls measured 22.4±2.0 msec and 41.8±2.9 msec respectively. Normal central motor conduction time(CMCT) was 9.7±1.6 msec and 19.3±2.3 msec respectively. The amplitudes of MEP were not reliable due to great variability. Abnormal responses were noted in 5 patients on the APB and in 12 patients on the EDB motor evoked potentieal studies. Mean latency and CMCT were significantly prolonged in involved sites of the other 16 patients, comparing with control data. Prolonged latency and CMCT, increased inter-side difference of CMCT. Any potential was not a useful indicator in determining abnormality of MEP study. More paralyzed patients were apt to show abnormal responses in MEP studies. There were also more abnormal results during acute stage compared with chronic stage More abnormal results were observed in the patients with cerebral cortex or corona radiata involvements. It is suggested that MEP study is a useful and sensitive method in the evaluation of stroke patients and be a effective method for further understanding of central motor system.
흔치않은 대상포진 치험 2예 : 비전형적 부위와 다른 부위로 재발한 예 Unusal Dermatome and Recurs Other Dermatome
김정미,조은경,조정선,최용석,한영수,한정호,김두응,최진영 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-
Herpes zoster is well known as an acute, self-limited disease of unilateral sensory dermatome caused by varicella-zoster virus and characterized by grouped vesicular skin eruption and pain over several dermatomes as well as single. This virus usually affects the thoracic dermatome and there are a few reports that this virus involves lower lumbar or sacral area, and recurrent cases. We experienced 2 cases that zoster virus involved L4 or S2 dermatome and left typical skin lesions, of which one was a recurrent case involving different dermatome at an interval of 8 years and the other was a rare case involving sacral dermatome.
데빅병 치료에 사용한 Interferon β-1b의 부작용 1예
김정미,조은경,조정선,최용석,한영수,한정호,김두응,최진영 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-
A 63 year-old woman who had diagnosis of multiple sclerosis complaining left hemiparesis and fluctuating decreased visual acuity in her right eye and abnormal findings in pattern shift visual evoked potentials(PSVEPs) and on T2 weighted MR scanning. We treated her subcutaneously with 250μg interferon (3-lb(ITFß -lb) every other day. There were detected pancytopenia, skin rash, and abnormal liver function test seven days after the therapy. In spite of reducing the dose of interferon injection, abnormal laboratory findings were not returned to normal. Dose adjustment of interferon-I3 for body weight or race, may be helpful to reduce the side effects.