미량금속 폭로에 있어 생체시료의 특성(제1보)

김대선,김동술,이원창 한국환경보건학회 1991 한국환경보건학회지 Vol.17 No.1

These studies were carried out to find out some characteristic responses of biological samples under the exposure of trace metals. In animal experiment, six rats per week were killed for 6 weeks under Cd exposures and the concentrations of Cd, Cu and Zn in their organs and blood were determined by flame atomic absorption spectrophotometry.The results were summarized as follows: In animal experiments, the concentrations of Cd in the liver and kidney of Cd exposure groups were increased, however, the values of hematocrit and hemoglobin in blood were decreased remarkably. The body weight of the Cd exposure groups showed lower trend than that of control group. The concentrations of Cd in heart, lung and testes were increased slowly during the first 2 weeks. The concentrations of Cd in their organs decreased while the rapid increase of the concentration of Cd in the liver and kidney was observed. While rapid increase of the concentra~ion of Cd in the liver and kidney was observed, the concentrations of Cd in the organs were decreased afterward and increased again while the low increase of the concentration of Cd in the liver and kidney was observed. The concentrations Cu and Zn were increased remarkably in all the organs for first 2 and 3 weeks. In the exposure groups of Cd+Cu and Cd+Zn, the liver and kidney didn't show lower concentration of Cd than that of Cd group.

시공간 통계기법을 활용한 해양공간정보의 정책분야 활용방안

김대선 해양환경안전학회 2020 해양환경안전학회 학술발표대회 논문집 Vol.2020 No.06

Global Trends in Mercury Management

김대선,최경희 대한예방의학회 2012 예방의학회지 Vol.45 No.6

The United Nations Environmental Program Governing Council has regulated mercury as a global pollutant since 2001 and has been preparing the mercury convention, which will have a strongly binding force through Global Mercury Assessment, Global Mercury Partnership Activities, and establishment of the Open-Ended Working Group on Mercury. The European Union maintains an inclusive strategy on risks and contamination of mercury, and has executed the Mercury Export Ban Act since December in 2010. The US Environmental Protection Agency established the Mercury Action Plan (1998) and the Mercury Roadmap (2006) and has proposed systematic mercury management methods to reduce the health risks posed by mercury exposure. Japan, which experienced Minamata disease, aims vigorously at perfection in mercury management in several ways. In Korea, the Ministry of Environment established the Comprehensive Plan and Countermeasures for Mercury Management to prepare for the mercury convention and to reduce risks of mercury to protect public health.

Challenges of Medical Waste Treatment in Fiji

김대선,Josefa Bolaqace,Eric Rafai,이철우 적정기술학회 2020 적정기술학회지(Journal of Appropriate Technology) Vol.6 No.1

Medical waste is any kind of waste that contains infectious material and recommended not to be transferred for infection control. As a means of disposal, incineration has better points than dumping or landfill in the quantity reduction, odorless and nonhazardous. However, open burning and incineration of health care wastes under bad circumstances, can result in the emission of environmental pollutants to air. A burial of biological waste brings pollution of soil and water. Most of sub divisional hospitals in Fiji transfer their medical wastes to divisional hospitals for incineration. In 2011, 62,518 kg of medical waste was incinerated in the three divisional hospitals. However, some medical wastes are considered as general waste and burnt or sent to landfill site, some are buried on site in some sub-divisional hospitals. In this regards, urgent education is necessary for awareness promotion to relevant personnel in medical waste treatment. On site incineration using small scale incinerator is more recommended than transportation of medical wastes treatment in Fiji. Moreover, remotely controllable and fixable small scale of incinerator is more desirable in sub-divisional hospitals. It is recommended that Fiji government to set up a legal framework for medical waste management (MWM), to develop specific guidelines for MWM, to set up a training system for MWM to ensure that all relevant personnel are trained, to develop a monitoring and supervision system for MWM, to clarify the future financing of MWM activities, and to improve the MWM infrastructure.

봄철 미세분진이 북경시 아동 폐기능에 미치는 급성영향에 관한 연구

김대선,유승도,차정훈,안승철,차준석 한국환경보건학회 2004 한국환경보건학회지 Vol.30 No.2

To evaluate the acute effects of fine particles on pulmonary function, a longitudinal study was conducted. This study was carried out for the schoolchildren (3rd and 6th grades) living in Beijing, China. Each child was provided with a mini-Wright peak flow meter and a preformatted health symptom diary for 40 days, and was trained on their proper use. Participants were instructed to perform the peak flow test three times in standing position, three times a day (9 am, 12 pm, and 8 pm), and to record all the readings along with the symptoms (cold, cough, and asthmatic symptoms) experienced on that day. Daily measurement of fine particles (PM$_{10}$ and PM$_{2.5}$) was obtained in the comer of the playground of the participating elementary school for the same period of this longitudinal study. The relationship between daily peak expiratory flow rate (PEFR) and fine particle levels was analyzed using a mixed linear regression models including gender, height, the presence of respiratory symptoms, and daily average temperature and relative humidity as extraneous variables. The total number of students participating in this longitudinal study was 87. The range of daily measured PEFR was 253-501$\ell$/min. In general, the PEFR measured in the morning was lower than the PEFR measured in the evening (or afternoon) on the same day. The daily mean concentrations of PM$_{10}$ and PM$_{2.5}$ over the study period were 180.2$\mu\textrm{g}$/㎥ and 103.2$\mu\textrm{g}$/㎥, respectively. The IQR (inter-quartile range) of PM$_{10}$ and PM$_{2.5}$ were 91.8$\mu\textrm{g}$/㎥ and 58.0$\mu\textrm{g}$/㎥. During the study period, the national ambient air quality standard of 150$\mu\textrm{g}$/㎥ (for PM$_{10}$) was exceeded in 23 days (57.5%). The analysis showed that an increase of 1$\mu\textrm{g}$/㎥ of PM$_{10}$ corresponded to 0.59$\mu\textrm{g}$/㎥ increment of PM$_{2.5}$. Daily mean PEFR was regressed with the 24-hour average PM$_{10}$ (or PM$_{2.5}$) levels, weather information such as air temperature and relative humidity, and individual characteristics including gender, height, and respiratory symptoms. The analysis showed that the increase of fine particle concentrations was negatively associated with the variability in PEFR. The IQR increments of PM$_{10}$ or PM$_{2.5}$ (at 1-day time lag) were also shown to be related with 1.54 $\ell$/min (95% Confidence intervals: 0.94-2.14) and 1.56$\ell$/min (95% CI: 0.95-2.16) decline in PEFR.R.ine in PEFR.ine in PEFR.

수은 고노출 지역 초등학생의 수은노출관련 건강영향 연구

김대선,안승철,정희웅,권영민,최경희,Kim, Dae Seon,Ahn, Seung Chul,Chung, Hee-Ung,Kwon, Young Min,CHOI, Kyunghee 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.4

Objectives: According to the 2007 Korea National Environmental Health Survey (KNEHS), some areas in the Gyeongsang Provinces showed very high blood mercury levels in adults. We conducted this project to investigate any related health effects in children due to mercury levels in these areas. Methods: In total, 1,097 students between grades 3 and 6 at 19 elementary schools were recruited from four areas with high mercury exposure as identified by the KNEHS. Total mercury levels in biological samples were compared with health check-ups performed on the schoolchildren. Biological monitoring, supported by questionnaires, a computerized neurobehavioral test, a posturography test and a personality test, were applied. Results: Triglycerides showed a significant relation with mercury in blood, urine and hair. Total mercury concentrations were divided into two groups: upper and lower concentration groups based on the median value. In the computerized neurobehavioral test, the upper blood mercury group showed a greater reaction time for color-word vigilance (p<0.05). In the posturography test, the intensity value of the tremor test showd high significant relations with mercury levels (p<0.01). In the personality test, self-consciousness, misdeeds and family relationships showed significant differences between the upper and lower urine mercury groups (p<0.01), and specific reactions, ego resilience and hyperactivity also showed some differences (p<0.1). Conclusion: Some items in the neurobehavioral test, posturography test and personality test showed significant relations with biological mercury levels. Therefore, monitoring and appropriate management of students showing high mercury levels are recommended in order to reduce their mercury exposure.

해양공간 정책시뮬레이터 개발방향

김대선,이문숙 해양환경안전학회 2023 해양환경안전학회 학술발표대회 논문집 Vol.2023 No.04

초기유아식내 Zn함량과 추정일일 Zn섭취량

김대선,하만광 한국식품위생안전성학회 1987 한국식품위생안전성학회지 Vol.2 No.4

A survey to determine the zinc content of early-infant food sources was conducted. Collected samples from various lots were human milk from volunteer mothers and infant formula and market milk from markets. The determined results by Atomic absorption Spectrophotometer were as follows: 1. Averages of Zn were 201$\pm$144 $\mu\textrm{g}$/dl in human milk, 2.243$\pm$0.888 mg/100g in infant formula, 292$\pm$90$\mu\textrm{g}$/dl in market milk and showed the decline trend by the lactation periods in human milk. (p<0.01) 2. Estimated daily intake of Zn from human milk was higher than that from infant formula in 3 months old infants.

해상감시체계 구축을 위한 위성영상 활용방안

김대선,양희철 해양환경안전학회 2021 해양환경안전학회 학술발표대회 논문집 Vol.2021 No.11

천리안위성 해수면온도 3차산출물 생성기법 비교연구

김대선,김광진,조재일,정성래,이양원 건국대학교 기후연구소 2015 기후연구 Vol.10 No.1

The COMS (Communication, Ocean and Meteorological Satellite) has been used in numerical weather prediction and meteorological monitoring over East Asia and Oceania since it has been launched in 2010. For more active utilization in climate research, the COMS level 3 products should be available in appropriate spatial and temporal resolutions. We compared different methods to generate monthly sea surface temperature (SST) products from the COMS time-series data. We employed three techniques for aggregating the time series, which are arithmetic mean, timeslot average, and moving average, and also used mean ensemble of them. Each level 3 dataset around South Korea was compared with monthly SST product from the Moderate Resolution Imaging Spectroradiometer (MODIS) of Aqua satellite during April 2011-March 2014. The timeslot average showed better root mean squared difference (RMSD) during the initial operational period of the COMS, when the retrieved values could be somewhat unstable. Daytime aggregations were derived more accurately by using the arithmetic mean or moving average, and the accuracy of nighttime aggregation was improved by the mean ensemble. Also, the timeslot average presented reasonable results particularly for coastlines where the standard deviation and missing value ratio were greater than normal. Because an optimal aggregation technique was variable depending on spatial and temporal conditions, we should be careful in selecting appropriate method for generation of the COMS level 3 products according to research objectives.