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      • SCIESCOPUSKCI등재

        Gypsy transposable element 를 사용한 초파리의 억제유전자 su ( s ) 2 의 cloning

        김재섭,박영식,임정빈 ( Jae Seob Kim,Young Shik Park,Jeong Bin Yim ) 생화학분자생물학회 1987 BMB Reports Vol.20 No.1

        The suppressor of sable mutant allele [su(s)²J of Drosophila melanogaster was cloned by the use of gypsy-transposable element tagging technique. The su(s)²; pr^(bw)cn genomic library of 8-11 kb size-range was prepared into the Hind III site of pUC 9 vector. The recombinant plasmids were screened with ^(32)P-labeled gypsy probe and the positive clones were rescreened by restriction endonuclease analysis. The presence of su(s)² sequence was confirmed by in situ hybridization of the biotinylated probe to the polytene chromosomes of su(s)²; pr^(bw)cn, pr^(bw)cn and Oregon-R strains. The restriction map of the su(s)² clone (named pYDS 2) was shown to be different from that of su(s)^+. The pYDS 2 contained another DNA sequence, 1.5 kb in length, besides the gypsy insertion.

      • 8-VSB DTTB 송신을 위한 최적 ERP와 안테나 HAAT에 관한 연구

        김재섭,임승우 한국컴퓨터산업학회 2001 컴퓨터産業敎育學會論文誌 Vol.2 No.9

        본 논문에서는 현재 운용되고 있는 NTSC TV송신시스템을 근거로 곧 설치되어 운용될 예정인 8-VSB DTV 전송시스템의 재원을 설계한다. 먼저 아날로그 NTSC와 디지털 8-VSB DTV의 지상파 방송의 경우 최적의 수신전계를 유지할 수 있는 조건을 검토한다. 또한 Longley-Rice의 전계강도 산출법을 이용해서 수신을 위한 최소한의 전계강도의 임계값을 산출한다. 8-VSB DTV전송은 NTSC 6MHz대역에서 HDTV가 가능하도록 19.39Mbps의 데이터를 고속으로 전송하는데 그 목표를 두고 있으므로, 무엇보다 송ㆍ수신점 사이의 전계강도의 최적화가 중요한 문제이다. 따라서 8-VSB DTV전송은 NTSC 서비스 커버리지에 비하여 확장되거나 효율적이어야만 한다. 끝으로 NTSC TV가 8-VSB DTV와 동일한 서비스 커버리지를 유지하기 위하여 NTSC VHF에서 DTV UHF로 전환 시 필요한 송신출력과 NTSC UHF에서 DTV UHF로의 전환 시 필요한 송신출력을 산출한다. In this paper, we make plans for facilities, the 8-VSB DTV transmission system, installed in the near future, based on presently NTSC TV operating it. First of all we estimate transmission power for analog NTSC, digital 8-VSB terrestrial broadcasting and the effective condition of optimal receiving power result from it. It's also to estimate optimal receiving condition by using Longley-Rice's Field Strength calculating method that is to guess a profile between transmitting station and many receiving points. The 8-VSB DTV Propagation aims to high-speed transmission rates of 19.39Mbps datum to enable HDTV(High Definition Television) at NTSC 6MHz bandwidth. First of all, an optimization of field strength between transmission station and receiver must deal with considerable. Because of these reasons, 8-VSB DTV transmission needs effective extension for NTSC TV service coverage. Finally we present the transmitting output that is expected in changing NTSC VHF to DTV UHF for maintaining the transmitting output of NTSC TV that is equal to 8-VSB DTV in service coverage.

      • 肺吸蟲症의 X-線學的硏究

        金在燮 中央醫學社 1964 中央醫學 Vol.7 No.6

        A group of 41 puppies and adult dogs were subjected to artificial infection with metacercariae of Paragonimus Westermani, and x-rays were taken at one week intervals. Then a ccmparative study was made with the roentgenological findings and the histopathological findings of autopsy. Bithionol treatment was given to 8 of these animals in order to make a comparative observation with the control group, and the following results were obtained: 1) Roentgenological findings of the experimental pulmonary paragonimiasis are classified as increasing in lung markings, pneumothorax, infiltrative, nodular and. ring shadows, pleural effusion, pleural thickening with adhesions and hilar enlargement. In this experiment pneumothorax and infiltrative shadows appeared in two, weeks following infection, formation of nodular and ring shadows in three weeks. After 4―5 weeks all of the above findings appeared in all infected cases but the ether findings were observed only in a few infected cases. 2) The outstanding pathological changes in the lung tissue within 3―4 weeks of infection were hemorrhagic and exudative inflammations due to invasion of the worms. The subsequent changes, such as exudative and proliferative inflammations in the worm cysts and around them were noted at the end of 7―8 weeks after infection. From 8―10 weeks following infection and thereafter, proliferative inflammations were also observed in the firmly established worm cysts, nodular worm eggs and around them. 3) It wr s assumed the t the pneumothorax was produced by the injury to the pleura caused by the worms; the infiltrative shadows are due to exudative inflammations; the nodular shadows are caused by the worm cysts and ether well-defined lesions and the ring shadows are caused by the air-containing worm cysts which are communicating with the bronchus. The shadows cf foci cf infection as appeared on the x-ray which frequently increase cr decrease in size and density, and are disappearing, interchanging or appearing as a new form are chiefly attributable to instability of lesion. 4) Of the 33 untreated cases cf the experimental pulmonary paragonimiasis, the total number of worm cysts and ether lesions determined by autopsy was 364 in contrast with the, number of shadows of lesions detected by x-ray taken immediately preceeding autopsy was 301 which correspond to 82.4% of the autopsy findings, Throughout the autopsy findings and the roentgenological examinations the right lung harbored mere lesions than the left. 5) Among the shadows cf the lesions as appeared in the x-rays of the experimental pulmonary paragonimiasis with Bithionol therapy, it is worth noting that the homogeneous infiltrative shadows most rapidly decrease and disappear or tend to stabilize, and the same changes take place in the ring, nodular and non-homogeneous shadows in order mentioned, It is, therefore, understood that these tendencies are attributable to diminution cf hemorrhage and inflammation, shrinking and collapsing of worm cysts including degenerative changes and death with eventual dissolution of worms. 6) In view cf this experimentation the characteristic appearing of infiltrative, nodular and ring shadows and their subsequent changes are not only significant guides to diagnosis of human pulmonary paragonimiasis but the process of comparatively rapid decrease and disappearance or stabilization following administration of drug may also be very helpful to determine their healing process as well as diagnosis. (II) Roentgenological Studies of the Human Pulmonary Paragonimiasis In cases of proven pulmonary paragonimiasis, routine x-ray films of 610 patients, tomograms of 35 patients and follow-up x-rays of 110 cases who have been treated with Bithionol were studied and the following results were obtained: 1) Of the 610 cases of routine x-rays 75 cases (12.3%) were found to be negative while the rema ining 535 cases (87.7%) showed positive pathology, such as infiltrative shadows were found in 70% of the total 640 cases, nodular shadows in 48.2% and ring shadows in 44.7% respectively, The total number of cases which showed such shadows were 513 cases (84.1%), From the standpoint of radiographic anatomy they are characteristic of pulmonary paragonimiasis, and may be recognized as essential findings. The other accompanying findings were pleural thickening with adhesions in 69.4% of the total cases, increased lung markings in 16.4%, pleural effusion in 10.5%, hilar enlargement in 7.9% and pneumothorax in 7.2%. Streaked shadows, tunnel observed-in a few cases. In consideration of the above findings the essential findings constitute the jority of 610 cases observed, and they provided a strong evidence for feasibility of radiographic diagnosis of pulmonary paragonimiasis. 2) The size of pathological shadows varied from a smallest ring shadow of pin-point to a largest infiltrative shadow covering one-third of one lung field. But in majority the infiltrative shadows varied from thumb-tip to walnut size, the nodular shadows being 5―10mm. and the multiform ring shadows ranged from 2 to 5mm, in diameter. 3) In observing the distribution of pathological shadows, it was found that there were more in the right lung field than in the left, in the lower field 34.3%, in the middle field 34.1%, in the upper field 31.3% the lowest while the apicies contained only 3.3%. Such a tendency as there were less involvements in the upper lung field than in lower is distinctively different from that of pulmonary tuberculosis, and it seems to be significant in making differential diagnosis radiographically. 4) It is assumed that the instability of infiltrative, nodular and ring shadows as shown by the frequent appearence of-increasing or decreasing in size and density; or undergoing disappearance, interchange and new formation was the results of changeable inflammatory reactions against worms and their products in cases of the infiltrative and nodular shadows, and depending on the conditions of air content in the cysts in case of ring shadows. It is, therefore, thought that such changes are characteristic findings in pulmonary paragonimiasis. 5) The accompanying findings as appeared in the radiograph were not s %ecific for this pathology but they provide diagnostic clue for pulmonary paragonimiasis since they appeared in ?7.7% of the total cases Especially the pleural thickening with adhesions as noticed in high rntio of 69.4% of all cases may serve as a high diagnostic value. 6) Tomograms are advantageous in diagnosis of pulmonary paragonimiasis, for they eliminate the interfering shadows and the inter-burying and inter-superimposing in the pathological shadows themselves, thereby the structural changes can be observed in detail as the contrast of the pathological shadows increases considerably. Furthermore, the shadows which fail to show up on the routine radiography may appear by this method. 7) About half the total number of radiographic pathological shadows disappeared after completion of treatment with Bithionol, about three-quarters after 4―6 months and the majority disappeared after 16―18 months. It was also noted that two months after treatment the interchanging and new forms disappeared from the shadows. The effect of Bithionol which directly reflects upon the x-ray fndings was so rapid that determination of therapeutic effect as well as differential diagnosis of the pulmonary paragonimiasis is made quite possible during comparatively early stage of treatment.

      • KCI등재
      • KCI등재

        재활요양병원의 재활군 환자의 만족도 요인에 관한 연구

        김재섭,장윤정 보건의료산업학회 2016 보건의료산업학회지 Vol.10 No.4

        Objectives : The aim of this study was to investigate the satisfaction determinants of rehabilitation care group inpatients in rehabilitation long-term care hospitals. Methods : A survey was conducted with 262 patients from 6 rehabilitation long-term care hospitals located in Busan·Kyungnam. Data were collected from June 2016 to July 2016 with a structured questionnaire and analyzed with SPSS 23.0. Results : The significant factors affecting the overall satisfaction score were disease group and 5 quality indices of medical services(Medical service quality, Rehabilitation services quality, Hospital reputation, External physical environment, and Internal physical environment). Additionally, the significant factors affecting intention to revisit were age, disease group, length of hospital stay and the 5 quality indices of medical services. Conclusions : The results of this study indicate that rehabilitation long-term care hospitals should try to improve the overall satisfaction of inpatients, especially focusing on the internal physical environment and the quality of the rehabilitation services and medical services, which will lead to a high level of intention for patients to revisit.

      • KCI등재

        교외지역 전파환경을 위한 예측모델 제안

        김재섭,박창균,Kim, Jae-Sub,Park, Chang-Kyun 한국음향학회 1997 韓國音響學會誌 Vol.16 No.4

        무선통신에서 전파환경을 보다 정확히 예측하는 것은 통신서비스 영역의 결정, 최적의 기지국선정 그리고 셀 설계 등을 위해 매우 중요하다. 따라서 안테나의 종류와 지향각 그리고 지형지물의 형태에 따라 변화하는 전파예측모델을 정확히 제시하므로써 통신망을 경제적으로 운용할 수 있음은 물론 통화품질과 가입자 서비스 또한 향상시킬 수 있을 것이다. 본 논문에서는 현대 교외지역 전파환경을 위한 최적 전파예측모델을 제안하기 위해 실험 대상지역으로 전남 나주시 세지 기지국을 선택, 전계강도를 실측하고, 이 결과를 토대로 전파예측모델을 제안한다. 제안모델은 지금까지 제안된 여타 예측 모델에서 고려되지 않았던 기지국과 이동국 안테나 유효높이의 상대차를 보정계수로 추가 활용하므로써 오차를 최소화 할 수 있었고, 제안모델과 Hata 모델, Egri 모델 그리고 Carey 모델의 컴퓨터 시뮬레이션(PPGIS)결과를 비교하므로써 그 적정성을 확인하였다. In mobile communications, it is very important that we predict the propagation environments of radiation pattern, in order to decide the service area, select the best location of the best station, design the cell etc. Therefore, by analyzing the propagation prediction model that is varied according to the kind of antenna, the beam angle, the terrain and obstacles, we expect that the economic operating of communication networks, the calling quality and the service of subscriber will be enhanced. In this paper, we select the around of Seji base station in Naju-city Chonnam for modern suburban area and measure the field strength to propose the optimal propagation prediction model for suburban areas. We propose the propagation prediction model that, it is not found in the other models until now, consists of the correction coefficient with the relative differences of antenna effective height of the base station and mobile station for minimizing errors. Finally, comparing the results of the field test with the computer simulation(PPGIS : Propagation Prediction Geographic Information System) results for the Hata model, the Egri model, the Carey model and the propose model, we confirm the property of the proposed model.

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