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학문목적 한국어 학습자의 토론 수업 연구 - 학습자 간 유창성 평가를 중심으로-
김수미 ( Kim¸ Sumi ) 한국언어문화교육학회 2021 언어와 문화 Vol.17 No.3
T+his study aims to examine learners' perceptions through fluency evaluations among learners in academic-purpose Korean debating classes. For that, the discussion of 31 advanced learners was conducted fluency evaluations by fellow learners, and the debaters' utterances were transcribed and analyzed. The analysis results are as follows. First, regression analysis of factors that determine a debater's fluency shows that the variable that most influences the debater's fluency judgment is the frequency of use of the argument, and the proportion of non-fluent utterances is somewhat less influential than the frequency of use of the argument. Second, fellow learners judged debaters with low rates of non-fluent utterances to be linguistically fluent. This is different from previous research results that native language speakers judge foreign learners' speaking fluency by their speaking speed. Third, the factor that influenced the debater's judgment of content fluency was the frequency of use of the argument. Learners tend to perceive debaters who use arguments highly as fluent debaters. Fluent discussion speaking requires training for learners' ability to construct arguments, as in conventional discussions, and also involves speaking practice to reduce non-fluent speech. This study is valuable as a learner-focused study in that debating classes are paramount, and is significant in that they have discussed learners' fluency in a different direction from the study of learners' fluency judgments from the native language speaker's perspective. (Sookmyung Women’s University)
Kim, Kyung Beom,Kim, Hyun,Song, Eun Joo,Kim, Sumi,Noh, Insup,Kim, Cheal The Royal Society of Chemistry 2013 Dalton transactions Vol.42 No.47
<P>A simple and low cost chemosensor is described. This sensor could simultaneously detect three biologically important metal ions through fluorogenic (Zn<SUP>2+</SUP>) and chromogenic (Fe<SUP>2+</SUP>, Cu<SUP>2+</SUP>, and Zn<SUP>2+</SUP>) methods in aqueous solution. The sensor could function as a “turn-on” fluorescence receptor only to Zn<SUP>2+</SUP> ions. In addition, the sensor could be successfully applied to the detection of intracellular Zn<SUP>2+</SUP>. Meanwhile, the sensor displayed an obvious red color upon selective binding with Fe<SUP>2+</SUP>. Therefore, the sensor could serve as a useful tool for the discrimination of Fe<SUP>2+</SUP> from Fe<SUP>3+</SUP> in aqueous media. Moreover, the sensor also showed color changes from yellow to colorless upon selective binding with Zn<SUP>2+</SUP> and Cu<SUP>2+</SUP>, respectively. The detection limit of the sensor for Cu<SUP>2+</SUP> (1.5 μM) is far below the guidelines of the World Health Organization (30 μM) as the maximum allowable copper concentration in drinking water, and therefore it is capable of being a practical system for the monitoring of Cu<SUP>2+</SUP> concentrations in aqueous samples. These results provide a new approach for selectively recognizing the most important three trace elements in the human body simultaneously, for Zn<SUP>2+</SUP> by emission spectra and Fe<SUP>2+</SUP>, Cu<SUP>2+</SUP>, and Zn<SUP>2+</SUP> by the naked eye.</P> <P>Graphic Abstract</P><P>A cap-type Schiff base could simultaneously sense three biologically important metal ions through fluorogenic (Zn<SUP>2+</SUP>) and chromogenic (Zn<SUP>2+</SUP>, Fe<SUP>2+</SUP>, and Cu<SUP>2+</SUP>) methods in aqueous solution. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3dt51916c'> </P>
Zinc sensors with lower binding affinities for cellular imaging
Kim, Jin Hoon,Hwang, In Hong,Jang, Seung Pyo,Kang, Juhye,Kim, Sumi,Noh, Insup,Kim, Youngmee,Kim, Cheal,Harrison, Roger G. The Royal Society of Chemistry 2013 Dalton transactions Vol.42 No.15
<P>Zinc sensors based on 2,3-dipicolylamine (DPA) and quinoline have been synthesized. They fluoresced in the presence of Zn<SUP>2+</SUP> and remained fluorescent when other metal ions were present. Fluorescence enhancement of the sensors was not seen for most other metal ions. <I>In vitro</I> studies with fibroblasts showed fluorescence when sensor and Zn<SUP>2+</SUP> were present. As seen by single crystal X-ray analysis, four nitrogens from the sensor bind to Zn<SUP>2+</SUP>. These new sensors have lower binding constants than the pentadentate sensors based on 2,2-DPA.</P> <P>Graphic Abstract</P><P>Molecules based on quiniline and bispicolylamine selectively bind Zn<SUP>2+</SUP> ions, fluoresce and cause fluorescence in cells exposed to Zn<SUP>2+</SUP>. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3dt33024a'> </P>
김수미(Sumi Kim),서희연(Hee Yeon Seo),이준호(Jun?Ho Lee),권용갑(Yong Kap Kwon),김성문(Seongmoon Kim),박인철(In Cheol Park),김승호(Seung Ho Kim),이영훈(Young Hoon Lee) 한국경영과학회 2010 經營 科學 Vol.27 No.1
Patients entering an emergency care center in a hospital usually visit medical processes in different orders depending on the urgency level and the medical treatments required. We formulate the patient flows among diverse processes in an emergency care center using the Jackson network, which is one of the queueing networks, in order to evaluate the system performances such as the expected queue length and the expected waiting time. We present a case study based on actual data collected from an emergency care center in a hospital, in order to prove the validity of applying the Jackson network model in practice. After assessing the current system performances, we provide operational strategies to reduce waiting at the bottleneck processes and evaluate the impact of those strategies on the entire system.
김수미(Sumi Kim),서희연(HeeYeon Seo),이준호(JunHo Lee),권용갑(YongKap Kwon),김성문(Seongmoon Kim),박인철(InCheol Park),김승호(SeungHo Kim),이영훈(YoungHoon Lee) 한국경영과학회 2009 한국경영과학회 학술대회논문집 Vol.2009 No.10
병원 응급실에 도착한 환자들은 위급한 정도와 필요한 치료에 따라 서로 다른 경로로 여러 프로세스를 따라 이동하는데, 본 논문에서는 여러 프로세스로 구성된 병원 응급실을 큐잉 네트워크 중 하나인 잭슨 네트워크를 이용하여 모델링하고, 이를 통하여 각 프로세스에서의 평균 대기 인원과 대기 시간을 평가한다. 그리고, 본 연구에서 제안한 잭슨 네트워크 모델에 국내 종합병원 응급실의 실제 데이터를 적용함으로써, 현재 각 프로세스의 대기 수준을 진단한 후, 특히 병목현상이 일어나는 프로세스들을 찾아 대기 수준을 개선하는 방안을 모색하고, 이것이 응급실 시스템 전체에 미치는 영향에 대하여 분석한다. Patients entering an emergency care center in a hospital usually visit medical processes in different orders depending on the urgency level and the medical treatments required. We formulate the patient flows among diverse processes in an emergency care center using the Jackson network, which is one of the queueing networks, in order to evaluate the system performances such as the expected queue length and the expected waiting time. We present a case study based on actual data collected from an emergency care center in a hospital, in order to prove the validity of applying the Jackson network model in practice. After assessing the current system performances, we provide operational strategies to reduce waiting at the bottleneck processes and evaluate the impact of those strategies on the entire system.
Mutations in gyrA and gyrB among Drug Resistant Mycobacterium Tuberculosis in Korea
( Hee Joo Lee ),( Hwi-Jun Kim ),( Ryeun Heo ),( Cheon-Tae Kim ),( Hee-Jin Kim ),( Jeong-hui Gwon ),( Gicheon Bae ),( Sumi Kang ),( Soul-hee Kim ),( Seungmo Kim ),( Eunseon Kim ),( Arim Song ),( Dea-Se 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.0
Purpose In 2020 KATRD, we analyzed 65 isolates to see how gyrA and gyrB are associated with 7H9 broth microdilution method (BMD) and Lowenstein-Jensen (L-J) drug susceptibility test (DST) because fluoroquinolones (FLQ) have been recognized as important anti-TB agents. In this study, the aim is to evaluate the correlation between gyrA and gyrB mutations and resistance to FLQ with BMD and L-J DST as a follow up of the previous study. Method Since 2020, we have analyzed 304 INH or RIF mono resistant cases by molecular DST using sequencing for gyrA and gyrB genes of FLQ. MICs were measured by BMD for moxifloxacin (MFX, 0.0625~8.0 μg/mL) and levofloxacin (LFX, 0.0625~8.0 μg/ mL). In L-J DST, concentration of MFX was 1.0 μg/mL, 2.0 μg/mL and LFX was 2.0 μg/mL. Results In gyrA and gyrB sequencing, 270 strains (88.81%) were wild type (WT), 34 strains (11.18%) were mutant type (MT). Among 29 gyrA MT strains, 13 isolates (44.82%) had mutation at D94G, 7 isolates (24.14%) at A90V and 5 isolates (17.24%) at D94A. Among 5 gyrB MT strains, 2 isolates (40%) had D500N mutation. In L-J DST, 100% of gyrA MT strains were resistant to MFX. On the other hand gyrB MT strains, 60% to MFX and 40% to LFX were resistant. In BMD, 93.10% of gyrA MT strains ranged 0.5 ~ 4.0 μg/mL and 60% of gyrB MT strains ranged 0.5 ~ 4.0 μg/mL to MFX. Meanwhile 96.55% of gyrA MT strains ranged 1.0 ~ 8.0 μg/mL and 80% of gyrB MT strains ranged 1.0 ~ 8.0 μg/mL to LFX. Conclusions Most of the mutant isolates had mutations in gyrA and most of mutant type (38.23%) was gyrA_D94G (GAC/GGC). In this study we observed gyrA genes were associated with higher MICs based on 7H9 and L-J DST than gyrB genes. # No.2021R1F1A1061358