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      • SCIESCOPUSKCI등재

        A Case of Hobnail Hemangioma

        (Shin Taek Oh),(In Gang Jang),(Sung Wook Kim),(Baik Kee Cho),(Seung Dong Lee) 대한피부과학회 2002 Annals of Dermatology Vol.14 No.1

        N/A Hobnail hemangioma(HH)is a benign acquired vascular tumor of endothelial origin which should be differentiated from other malignant vascular neoplasm such as Kaposi`s sarcoma or angiosarcoma.We report a case of hobnail hemangioma in a 21-year-old woman who had a dusky-red patch on her left shin.Histologically,ectatic vascular channels with a single layer of plumped endothelial cells were seen and the vascular channels seemed to dissect the collagen bundles.She underwent treatment with surgical excision with primary closure. (Ann Dermatol 14(1)45-47, 2002).

      • SCIESCOPUSKCI등재
      • 8-Azaxanthine과 그 유도체의 합성 및 시험관내 항암 활성

        李奉憲,辛貞姬,張太植,朴章洙,姜信源 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

        8-Azaxanthine(1), 3-β-D-ribofuranosyl-8-azaxanthine(2),3-β-D-ribofuranosyl-8-azaxanthine-5'-monophosphate(3), 그리고 3-β-D-ribofuranosyl-8-azaxanthine-5'-(3-pyridinylcarbonyl)monophosphate(4)를 합성한 후 Mouse leukemia P388,Murine mammary carcinoma FM3A, Human histiocytic lymphoma U937암세포들에 대해 시험관내 항암활성을 MTT를 이용한 방법으로 예측하고 IC_50(μmol/mL)으로 나타내었다. 그 결과, 비정상적인 염기의 N-3와 당의 C-1'glycoside결합을 가진 2는 세가지의 암세포에 대해 감수성이 좋아 IC_50이 각각 0.05, 0.06,0.06μmol/mL이었으나 항세균 활성 예측에서는 감수성을 보이지 않았다. Human histiocytic lymphoma U937세포에 대한 IC_50은 1이 0.33,2는 0.06,3은0.25그리고 4는 0.33μmol/mL로 구조 변화에 따라 서로 다른 값을 보였다. 8-Azaxanthine(1), 3-β-D-ribofuranosyl-8-azaxanthine(2),3-β-D-ribofuranosyl-8-azaxanthine-5'-monophosphate(3), 3-β-D-ribofuranosyl-8-azaxanthine-5'-(3-pyridinylcarbonyl)monophosphate(4) were synthesized. The in vitro antitumor activities of the synthesized compounds against P388 mouse leukemia,FM3A mammary carcinoma, and U937 human histiocytic lymphoma cells were determined by MTT assay. 2 with unnatural N-3 and C-1'glycoside bond had activityagnist three tumor cell lines and IC_50s of these compounds were 0.05,0.06μmol/mL against three tumor cell lines, repectively. But these compounds had no antibacterial activity. IC_50s aganist U937 human histiocytic lymphoma cells were verfied with the structural modification:IC_50s of 1,2,3, and 4 were 0.33,0.06,0.25, and 0.33μmol/mL, respectively.

      • KCI등재

        지하역사 승강장 및 대합실 평상시/비상시 급ㆍ배기 환기 Large Eddy Simulation

        장용준(Yong-Jun Jang),류지민(Ji-Min Ryu),박덕신(Duck-Shin Park) 한국전산유체공학회 2013 한국전산유체공학회지 Vol.18 No.3

        The turbulent flow behavior of air supply and exhaustion in the Shin-gum-ho subway station is analyzed for ordinary and emergency state. The depth of Shin-gum-ho station is 43.6m which consists of the island-type platform(8th floor in underground) and a two-story lobby (first & second floor in underground). An emergency stairway connects between the platform and the lobby. Ventilation operation mode for ordinary state is set up as a combination of air supply and exhaustion in the lobby and platform, while for emergency state it is set up as a full air supply in the lobby and a full exhaustion in the platform. The entire station is covered for simulation. The ventilation diffusers are modeled as 95 square shapes of 0.6m?0.6m in the lobby and as 222 square shapes of 0.6m×0.6m and 4 rectangular shapes of 1.2m×0.8m in the platform. The total of 7.5million grids are generated and whole domain is divided to 22 blocks for MPI efficiency of calculation. Large eddy simulation(LES) is applied to solve the momentum equation and Smagorinsky model(C<SUB>s</SUB>=0.2) is used as SGS subgrid scale) model. The time-averaged velocity fields are compared to experimental data and show a good agreement with it.

      • 비타민 복합섭취가 고강도 운동 후 면역세포에 미치는 영향

        신장호,위승두 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.4

        The purpose of this study is to investigate the effect of antioxidant-vitamins supplementation on exercise-induced acute phase response of T lymphocyte and natural killer cell(NK cell). B healthy college students(M, 27.9±2.2 yr) were participated in exercise sessions before and after 5 weeks antioxidant-vitamins supplementation. The exercise sessions included treadmill running at 110% AT level(high-intensity) until each subject reached to target exercise volume(301.3± 20.5 ㎉). Venous blood samples were drown at the forearm antecubital vein at rest, immediately after exercise, and 30min/90min recovery(15㎖ each). The results of this study can be summarized as follows: 1) There were significant changes in T lymphocyte proliferation responses after high-intensity exercise, and antioxidant-vitamins supplementation affected on the acute phase response(P<.05). 2) There were no significant changes in per-cell T lymphocyte proliferation responses after high-intensity exercise, but antioxidant-vitamins supplementation made it significantly higher(P=.05). 3) There were significant changes in NKCA after high-intensity exercise(P<.01), and antioxidant-vitamins supplementation affected on the acute phase response(P<.05). 4) There were significant changes in per-cell NK cell lytic unit after high-intensity exercise(P<.01), and antioxidant-vitamins supplementation made it significantly higher(P=.05).

      • SCIESCOPUSKCI등재
      • KCI등재

        재벌의 기업집단화에 관한 연구 : 日本の事例を中心に 일본의 사례를 중심으로

        申章澈 韓日經商學會 1999 韓日經商論集 Vol.18 No.-

        本硏究は,近代化以降の急激な政治および經濟的變化の過程なかで日本の大企業が果たした役割,なかでも戰前の'財閥'と戰後の'企業集團'の成長と變遷の過程に焦点を合わせたものである. すなわち,日本における戰前の財閥の企業集團化過程を時系列的にアブロ-チすることによつて,現在韓國で無分別に使われている財閥と企業集團との槪念を明確にし,その基本的な性格を明らかにすることに硏究の目的をおく. 本硏究をつうじて,日本の場合,少なくとも財閥と企業集團とは國民經濟に える影響やその位置において相當異なる側面が多いとんう認識が一般的であるごとが明らかになつた.さらに財閥と企業集團とは,その生成と歷史的な發展過程,企業形態および構造,そしてその性格と特徵が互いに偉う特質をもつ企業體として區別され通用されている. 一方,韓國では,近年において政府當局によつて進められている一連の'財閥改革'から見られるように,大企業,財閥,企業集團,企業グル-プなど,個別企業體の樣 な形態にたいする明確ながイドラインがいまだ示されていない狀況にある. 韓國經濟がごの頃の'IMF 制'から早期に脫出し,成長基調のもとの力を回復するためには,'大企業(30大)=財閥'だという一般國民が持つている歪んだ企業關と,韓國企業に對する外國からの否定的な認識を改めなければならない.ごのためには,學術的に財閥の觀念を明確にし,その本質的な側面を的確に把握するごとによつて,'大企業政策'または'財閥改革'の正當性と實效性を確保するごとが하よりも肝心であろう.

      • 강수량에 따른 유구천의 어류상과 어류군집에 관한 연구

        장민호,최신석,홍영표 충남대학교 기초과학연구소 1996 忠南科學硏究誌 Vol.23 No.2

        To investigate the community analysis of freshwater fish in Yugu-stream near Kongju, a Kumgang river's tributary, the field sampling was carried out from May 1995 to March 1996 at six different stations, with measuring environmental factors of the stream water. Among the environmental factors measured, total suspended solid altruistically increased in the rainy season (24.22 ㎎/l) than in the other seasons (2.38 ∼ 4.36 ㎎/l), while dissolved oxygen decreased in the rainy season (7.15 ppm). The fish collected during this survey were identified 6 families and 36 species, in which 11 species were endemic in Korea. The most dominant species was Zacco platypus with a relative abundance of 54.3%, that accords with a general tendency of the species in most of the Korean streams. Acheilognathus intermedia was observed with 13.4% and Acheilognathus rhombea with 4.3% abundance. Fish in the rainy season were identified 6 family and 32 species, that showed a little less diversity compared to fish in the other seasons. Hemiculter eigenmenni and Erythroculter erythropterus, which usually occur in the main stream of Korean rivers, also showed a relatively high abundance in Yugu-stream. Species richness of Yugu-stream fish increased with a index of 3.69 in the rainy season, while the fish diversity and evenness index decreased.

      • 아스피린 투여가 고온·최대운동 중 체온과 운동수행능력에 미치는 영향

        신장호 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.4

        The purpose of the present study was to determine whether aspirin affects on exercise performance and body temperature during exercise in high temperature, 20 college-age men performed a 70% VO₂max exercise on a treadmill on two different occasions, after aspirin(1000㎎ of aspirin) and placebo administration, Measurement of rectal temperature, mean body temperature, VO₂max, VEmax, fRmax Rmax and HRmax was carried out. There were no significant differences in rectal and mean body temperature between the two exercises, The analysis of HRmax, VEmax and fRmax showed statistically significant differences between before and aspirin administration, Duration of exercise did not change after aspirin administration, suggesting that aspirin administration(1000㎎) does not affect exercise performance in high temperature.

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