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Dong Gyun Lim,Kap Sung Choi,Jong Ju Kim3,Ki Chang Nam 한국축산식품학회 2013 한국축산식품학회지 Vol.33 No.2
The objective of this study was to evaluate the quality characteristics of sun-dried Hanwoo beef jerky added with Salicornia herbacea (SH). Sliced Hanwoo beef shank were marinated and sun-dried at 28-30oC, relative humidity (RH) 30-35% for 3.5 h. The physicochemical and microbiological traits of the Hanwoo beef jerky were analyzed during the aerobically packaged storage at 25oC. The water activities of beef jerky with 0.5% and 1.0% SH were lower than those of the control at 0 d (p
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김상균(Kim Sang Gyun) 한국공안행정학회 2005 한국공안행정학회보 Vol.20 No.-
The purpose of the present study were to compare of moral development level between delinquent adolescences and normal adolescences, and the help-ful date in understanding and guiding the delinquent adolescences. Based on the previous studies and Kohlberg's Moral development theory, it was hypothesized that there are difference of total and subfactoric moral development degree between delinquent adolescences and normal adolescences. Subject for the study were 298 boys(middle school:48/high school: 120/delinquent : 130) in Dae-Jeon. They were examine in Kohlberg's Moral development scale which rewrited by Kim Sang Gyun. Statistical methods applied for the present study was mean, standard deviation, and t-test. The statistical computation were done by SPSS 8.0 computer programs. Following conclusions were derived from the results and the discussion. 1. Hypothesis 1 was accepted. Delinquent adolescences had high score on moral development's means compare with normal adolescences. 2. Hypothesis 2 was partially accepted. Delinquent adolescences showed lower "stage 1, stage 2, stage 3" than normal adolescences. However, there were no significant differences of " stage 4, stage 5 and stage 6 " 최근 학교폭력, 청소년 성매매, 마약, 가출 등 청소년에 의한 범죄와 비행이날로 증가하고 있다.1) 이러한 상황은 자라나는 청소년들에게 급변하는 사회환경에 적절하게 대응할 수 있는 올바른 가치관과 도덕성 함양기능을 제대로 수행하지 못한 결과가 아닌가 생각한다. 최근 일각에서 청소년을 대상으로 한 인성교육의 중요성이 부각되고 있는 것은 다행스런 점이 있다. 이 논문은 Kohlberg(1976)의 도덕발달이론을 논거로 하여 비행청소년과 정상청소년간의 도덕적 추론능력의 차이를 비교한 연구이다. 그에 의하면 도덕의 발달단계에 따라 도덕적 지향의 형태가 달라지고, 도덕적 판단력의 형성에 있어서의 차이는 도덕적 행위나 비도덕적 행위에 관련이 있다고 한다. 논문에서 비행청소년의 도덕적 추론능력을 검증한 결과, 비행청소년은 전인습적 도덕성에 속하는 1, 2단계에 속하는 것으로 밝혀졌다. 또 이를 정상청소년을 준거집단으로 한 비교분석을 해 본 결과, 전인습적 도덕성에 속하는 1단계에서 유의한 차이가 있음이 밝혀졌으며, 이 외에 인습적 도덕성에 속하는 대인간의 조화와 순종의 단계에서도 유의한 차이가 발견되었다. 3단계인 대인간의 조화와 순종단계에서도 정상청소년과 유의한 차이가 있다는 의미는 비행청소년이 대인관계의 기술면에서 부족하다는 것을 나타낸다. 그 외의 단계에서는 비행청소년과 정상 청소년 간에 유의한 차이가 발견되지 않았지만 정상청소년은 콜버그의 도덕적 발달단계에서 상위단계에서도 비교적 높은 점수를 나타내고 있음을 볼 수 있다. 이러한 연구결과는 청소년을 대상으로 도덕성 함양교육 내지 인성교육이 중요함을 시사하고 있다.
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김상균(Kim Sang Gyun) 한국공안행정학회 2005 한국공안행정학회보 Vol.21 No.-
최근 학교폭력, 청소년 성매매, 마약, 가출 등 청소년에 의한 범죄와 비행이날로 증가하고 있다.1) 이러한 상황은 자라나는 청소년들에게 급변하는 사회환경에 적절하게 대응할 수 있는 올바른 가치관과 도덕성 함양기능을 제대로 수행하지 못한 결과가 아닌가 생각한다. 최근 일각에서 청소년을 대상으로 한 인성교육의 중요성이 부각되고 있는 것은 다행스런 점이 있다. 이 논문은 Kohlberg(1976)의 도덕발달이론을 논거로 하여 비행청소년과 정상청소년간의 도덕적 추론능력의 차이를 비교한 연구이다. 그에 의하면 도덕의 발달단계에 따라 도덕적 지향의 형태가 달라지고, 도덕적 판단력의 형성에 있어서의 차이는 도덕적 행위나 비도덕적 행위에 관련이 있다고 한다. 논문에서 비행청소년의 도덕적 추론능력을 검증한 결과, 비행청소년은 전인습적 도덕성에 속하는 1, 2단계에 속하는 것으로 밝혀졌다. 또 이를 정상청소년을 준거집단으로 한 비교분석을 해 본 결과, 전인습적 도덕성에 속하는 1단계에서 유의한 차이가 있음이 밝혀졌으며, 이 외에 인습적 도덕성에 속하는 대인간의 조화와 순종의 단계에서도 유의한 차이가 발견되었다. 3단계인 대인간의 조화와 순종단계에서도 정상청소년과 유의한 차이가 있다는 의미는 비행청소년이 대인관계의 기술면에서 부족하다는 것을 나타낸다. 그 외의 단계에서는 비행청소년과 정상 청소년 간에 유의한 차이가 발견되지 않았지만 정상청소년은 콜버그의 도덕적 발달단계에서 상위단계에서도 비교적 높은 점수를 나타내고 있음을 볼 수 있다. 이러한 연구결과는 청소년을 대상으로 도덕성 함양교육 내지 인성교육이 중요함을 시사하고 있다. The purpose of the present study were to compare of moral development level between delinquent adolescences and normal adolescences, and the helpful date in understanding and guiding the delinquent adolescences. Based on the previous studies and Kohlberg's Moral development theory, it was hypothesized that there are difference of total and subfactoric moral development degree between delinquent adolescences and normal adolescences. Subject for the study were 298 boys(middle school:48/high school: 120/delinquent : 130) in Dae-Jeon. They were examine in Kohlberg's Moral development scale which rewrited by Kim Sang Gyun. Statistical methods applied for the present study was mean, standard deviation, and t-test. The statistical computation were done by SPSS 8.0 computer programs. Following conclusions were derived from the results and the discussion. 1. Hypothesis 1 was accepted. Delinquent adolescences had high score on moral development's means compare with normal adolescences. 2. Hypothesis 2 was partially accepted. Delinquent adolescences showed lower "stage 1, stage 2, stage 3" than normal adolescences. However, there were no significant differences of " stage 4, stage 5 and stage 6"
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Clinicopathological role of kidney injury molecule-1 in immunoglobulin A nephropathy
( Yu Ho Lee ),( Yang-gyun Kim ),( Sang-ho Lee ),( Ju-young Moon ),( Kyung-hwan Jeong ),( Tae-won Lee ),( Chun-gyoo Ihm ) 대한신장학회 2014 Kidney Research and Clinical Practice Vol.33 No.3
Background: Urinary kidney injury molecule-1 (KIM-1) is an early and sensitivebiomarker of acute kidney injury, but it is unclear if it is a biomarker of chronicglomerulonephritis. We evaluated whether urinary KIM-1 levels in patients withimmunoglobulin A (IgA) nephropathy can be a marker to reflect clinicopathologicalseverity and predict the prognosis. Methods: We measured urinary KIM-1 levels in 40 patients (15 males; mean age36.6712.9 years) with IgA nephropathy and 10 healthy people (5 males; mean age37.379.6 years) as controls. The correlation of urinary KIM-1 levels with patients’clinical parameters, histological grades, and follow-up data were analyzed using themodified H. S. Lee grading system and tubulointerstitial change scores. Results: Urinary KIM-1 levels were higher in patients with IgA nephropathy thanhealthy controls (P¼0.001). Univariate and multivariate regression analyses showedthat urinary KIM-1 levels had a direct correlation with H. S. Lee grade andtubulointerstitial inflammation (P¼0.004 and P¼0.011, respectively). Conclusion: In patients with IgA nephropathy, urinary KIM-1 has a significantcorrelation with histopathologic severity.
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( Jae Young Jang ),( Soung Won Jeong ),( Sung Ran Cheon1 ),( Sae Hwan Lee1 ),( Sang Gyune Kim ),( Young Koog Cheon ),( Young Seok Kim1 ),( Young Deok Cho1 ),( Hong Soo Kim ),( So Young Jin ),( Yun Soo 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3
Background/Aims: We investigated the frequency of occult hepatitis B virus (HBV) infection in anti-hepatitis C virus (HCV)-positive individuals and the effects of occult HBV infection on the severity of liver disease. Methods: Seventy-one hepatitis B virus surface-antigen (HBsAg)-negative patients were divided according to their HBV serological status into groups A (anti-HBc positive, anti-HBs negative; n=18), B (anti-HBc positive, anti-HBs positive; n=34), and C (anti-HBc negative, anti-HBs positive/negative; n=19), and by anti-HCV positivity (anti-HCV positive; n=32 vs. anti-HCV negative; n=39). Liver biopsy samples were taken, and HBV DNA was quantified by real-time PCR. Results: Intrahepatic HBV DNA was detected in 32.4% (23/71) of the entire cohort, and HBV DNA levels were invariably low in the different groups. Occult HBV infection was detected more frequently in the anti-HBc-positive patients. Intrahepatic HBV DNA was detected in 28.1% (9/32) of the anti-HCV-positive and 35.9% (14/39) of the anti-HCV-negative subjects. The HCV genotype did not affect the detection rate of intrahepatic HBV DNA. In anti-HCV-positive cases, occult HBV infection did not affect liver disease severity. Conclusions: Low levels of intrahepatic HBV DNA were detected frequently in both HBsAg-negative and anti-HCV-positive cases. However, the frequency of occult HBV infection was not affected by the presence of hepatitis C, and occult HBV infection did not have a significant effect on the disease severity of hepatitis C. (Korean J Hepatol 2011;17:206-212)
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Mutational analysis of CASP10 gene in acute leukaemias and multiple myelomas
Kim, Min Sung,Oh, Ji Eun,Min, Chang Ki,Lee, Seok,Chung, Nak Gyun,Yoo, Nam Jin,Lee, Sug Hyung Elsevier 2009 Pathology Vol.41 No.5
<P>AIMS: Deregulation of apoptosis is one of the hallmarks of cancers. Inactivation of cancer cell apoptosis by somatic mutations has been reported in several cancers. Caspase-10 activation is important in the initiation phase of apoptosis. The aim of this study was to explore whether CASP10 gene that encodes caspase-10 is somatically mutated in acute adulthood leukaemias and multiple myelomas (MMs). METHODS: We analysed the entire coding region and all splice sites of CASP10 gene for the detection of somatic mutations in 60 acute leukaemias (25 acute myelogenous leukaemias, 35 acute lymphoblastic leukaemias) and 22 multiple myelomas by a single-strand conformation polymorphism assay. RESULTS: Overall, we found two CASP10 mutations in the cancers (2/82; 2.4%). One mutation [c.854T>C (pLeu285Pro)] was detected in a T-acute lymphoblastic leukaemia (T-ALL) (1/13 T-ALL; 7.7%). The other mutation [c.61C>T (p.Arg21Cys)] was found in an MM (1/22 MM; 4.5%). The mutations were identified in the coding regions of the death effector domain (p.Arg21Cys) and the p17 large protease subunit (pLeu285Pro). We observed both of the T-ALL and the MM with the CASP10 mutations well expressed the mutant CAS10 at mRNA level. CONCLUSION: Although our data indicate that somatic mutation of CASP10 is not common in T-ALL and MM, the data suggest a possibility that CASP10 mutation might contribute to the pathogenesis of factions of T-ALL and MM.</P>
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Kim, Sang-Gyun,Lee, Ki-Sub,Lee, Kew-Ho Wiley Subscription Services, Inc., A Wiley Company 2006 Journal of applied polymer science Vol.102 No.6
<P>Through the complexation of two anionic polysaccharide blends composed of sodium alginate and carrageenan with divalent calcium ions, polyelectrolyte complex membranes were prepared. The effects of annealing on the structure of the polyelectrolyte complex membranes and on their performance at removing water from a methanol mixture were investigated and discussed. The annealed membranes exhibited a change in their crystallinity. The change was due to a rearrangement of polymer chains, which was induced by a deformation of the chelate structure and intramolecular or intermolecular interactions between the polysaccharides. Because of the effects of annealing on the resulting membranes, water components almost penetrated the membranes to the permeate side in the vapor permeation process. Moreover, the membrane performances were gradually enhanced as the operating temperature increased. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 102: 5781–5788, 2006</P>
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Kim, Y.S.,Kim, Tae Gyun,Jung, Ui Won,Kim, C.S.,Choi, Seong Ho,Cho, Kyoo Sung,Kim, Chong Kwan Trans Tech Publications, Ltd. 2006 Key Engineering Materials Vol.309 No.-
<P>Dehiscence bone defects, frequently observed on dental implants placed in periodontitis-affected alveolar bone or extraction sockets were treated with β-tricalcium phosphate (β -TCP) and chitosan membrane for guided bone regeneration, and the new bone formation on the treated sites were studied. Beagle dogs were used for the experiment. First to fourth mandibular premolars were extracted, and the post extraction alveolar bone surface was planed. After 8 weeks of healing, 3 by 4mm dehiscence defects were created using straight fissure burs. Total of 16 oxidized titanium surface implants were placed on the bone defects of the subjects, two on each side. Control sites were treated with implants only. Experimental Group 1 sites were treated with implants and chitosan membrane. Experimental Group 2 sites were treated with implants, β-TCP and chitosan membrane. Experimental Group 3 sites were treated with implants, β-TCP, autogenous bone and chitosan membrane. The animals were sacrificed 12 weeks after implant placement, and the specimens from the treated sites were histologically studied with following results. Limited amount of new bone formation was observed in control group with unexposed membrane. Slightly greater amount of bone formation was observed on sites treated with β-TCP+membrane or autogenous bone+ β-TCP+membrane compared to control group. Remnants of chitosan membrane and β-TCP encapsulated with connective tissue were observed during experimental periods. These results suggest that further studies are needed on membrane rigidity and infection control for space maintenance underneath the membrane and bone substitutes in the treatment of dehiscence defects.</P>
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