백혈병 세포주에 대한 (±)-ar-Turmerone, 자근 및 황금추출물에 의한 항암제의 세포독성 증강효과

이윤영,유관희,김삼용,안병준 충남대학교부설 생명공학연구소 1992 생물공학연구지 Vol.2 No.-

Using the colorimetric [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide](MTT)assay, we evaluated the chemosensitivity of 8 anticancer drugs{vincristine(VCR), vinblastine(VBL), adriamycin(ADR), cisplatin(CPDD), etoposide(VP-16), cytosine arabinoside(ara-C), bleomycin(Bleo) and cyclophosphamide(CYC)} and the cytotoxicity-enhancing effects of (±)-ar-turmerone and the extracts of the crude drugs {Lithospermum erythrorhizon(LE) and Scutellaria baicalensis(SB)}on the above mentioned anticancer drugs against HL-60 and KG-1 cells among 8 anticancer drugs, VCR, VBL, ADR, and CPDD inhibited the growth of both cell lines by more than 50% while VP-16, ara-C, Bleo, and CYC were less effective. (±)-ar-Turmerone had significant inhibitory effects against both cell lines, showing the ID_50 values of 11.730 ㎍/㎖ and 0.292 ㎍/㎖ for HL-60 and KG-1 cells. respectively. But the extracts of LE and SB roots showed no significant cytotoxic effects. According to ID_50 values, the cytotoxicities of VCR, VBL and ADR against HL-60 were enhanced two, eight and three times by mixing (±)-ar-turmerone, five, seven and three times by adding the extract of LE root, and twenty, six and three times by mixing the extract of SB root, respectively. The cytotoxicities of the above mentioned drugs against KG-1 cell were enhanced two, seven and three times by mixing (±)-ar-turmerone, two, three and three times by conbining wilth the extract of LB root, and two, five and two times by adding the extract of SB root, respectively. The cytotoxicity-potentiating effects of (±)-ar-turmerone and the extracts of LE and SB roots against HL-60 cell were greater than KG-1 cell.

영어 낱말 강세 규칙의 활용

구희산,이순향 中央大學校 韓國敎育問題硏究所 1996 韓國敎育問題硏究所論文集 Vol.- No.11

This article suggests a set of revised English stress rules which English teachers can apply in class. The revised rules are drawn from the word stress rules by chomsky & Halle, Kreidler and Liles. The rules are as follows: Condition 1. If the noun has the last lax vowel, the rule is applied to the rest of the noun except the last syllable. Condition 2. The suffix of a word, as -ly, -ment, -hood, -ing, cannot change the stress of root Rule 1. place stress on the last tense vowel of a word Rule 2. Place stress on the last vowel of a word if it is followed by a cluster of two or more consonants. Rule 3. Place stress on next to the last vowel of a word if neither of the above conditioon is met. The rules can help English teachers easily predict where the primary stress is placed in simple words and words with affixes.

C.V.D. 방법에 의한 Cd_0.78Zn_0.22 S박막 성장과 광전기적 특성연구

유상하,이상렬,홍광준,서상석,김혜숙,전승룡,윤은희,문종대 조선대학교 기초과학연구소 1993 自然科學硏究 Vol.16 No.1

We had grown Cd_0.78Zn_0.22S polycrystal thin films on slide substrate using chemical vapour deposition(CVD) method. We measured X-ray diffraction patterns in order to study Cd_0.78Zn_0.22S polycrystal structure. We studied its band gap using transmission curves and photocurrent and also analyzed photoluminescence using configurational coordinate model. We measured Hall effect·on this sample by Van der Pauw method and studied on carrier density and mobility depending on temperature.

한국학생들의 영어 고모음 발음에 대한 연구

황석봉,이순향,구희산 中央大學校 韓國敎育問題硏究所 1998 韓國敎育問題硏究所論文集 Vol.- No.13

The purpose of this study was to investigate the pronunciation problem on high vowel in English, and to think about the resolution of it. The subjects of this experiment were 10 Korean high school students, and their identifying ability on /i, ι, u,υ/was measured. The result was that subjects could identify tense vowels better than lax vowel. That is, the pronunciation problem of high-vowels appears to be in lax vowel. The resolution was suggested that (a) English teachers and students should know that the difference of tense from lax vowel is in sound quality, not in duration; (b) to identify the high vowels, teachers should use in the classroom the tape that English native speakers record the minimal pair-words including the high vowels.

중압 배전망에서의 전력선 통신을 위한 OFDM 기법의 성능 분석

임장규,김산해,장희동,이원철,신요안 崇實大學校 生産技術硏究所 2002 論文集 Vol.32 No.-

Recently, PLC (Power Line Communication) on medium voltage power lines have been gaining much attention for high data rate access networking. In this paper, we evaluate the performance of OFDM (Orthogonal Frequency Division Multiplexing) schemes on medium voltage power line channels in the frequency range up to 20 ㎒. We analyze fading characteristics of multi-path channel models for medium voltage power lines, and simulations have been carried out for the OFDM using adaptive bit loading scheme. Simulation results indicate that the OFDM schemes with the adaptive bit loading show good bit error rate performance under harsh medium voltage power lines channel.

리듬체조 Ring jump동작의 운동학적 분석

우병훈,인희교,이계산 한국운동역학회 2002 한국운동역학회지 Vol.12 No.2

본 연구는 리듬체조를 구성하는 기술 중에서 신체 기본요소군의 Jump에 포함되는 C난도 Ring jump의 3차원 동작분석을 통해 분석하여 선수들의 기술향상과 지도에 필요한 정량적 자료를 제공하는데 목적을 두었다. 이벤트별 소요시간에서는 E-3에서 0.409±0.017sec로 가장 긴 소요시간을 보였다. 신체중심의 변위에서는 E-3에서 88.5±1.3%로 가장 높은 높이를 보였다. 좌 · 우 발끝 속도에서는 E-2에서 각각 732.4±46.1cm/sec, 1958.4±625.1cm/sec로 가장 빠르게 나타났다. 상체후경각에서는 E-3에서 97.98degree로 가장 낮은 각도를 보였다. 슬관절 각변위에서는 E-3에서 좌 · 우 각각 69.2±5.7degree로 가장 낮은 각도를 보였다. 족관절 각변위에서는 E-3에서 좌 · 우 각각 171.3±6.9degree로 가장 큰 각도를 보였다. 이런 결과로 볼 때, Ring jump동작을 수행하기 위해서는 족관절의 신전을 통한 높은 점프로 상체를 후경할 수 있는 유연성과 체공을 시간을 갖추는 것이라고 사료된다. The study has a goal that produces abundant documents that needed for athletes to teach and progress skills by analyzing 3-dimensional action analysis of C-difficulties Ring jump included in body original elements among techniques constructing Rhythmic Sport Gymnastics. 1. It was the longest applied time delay that E-3 indicates 0.409±0.017sec in each event applied time delay. 2. It was the tallest height that E-3 indicates 88.5±1.3% in displacement of body's center. 3. It was the fastest velocity in E-2 where the velocity of left foot is 7.32.4±46.1cm/sec, the velocity of right foot is 1958.4±25.1cm/sec. 4. the lowest angle was founded at 97.8 degree in the E-3 on the trunk extension angle. 5. The lowest angle of both sides were seen at 92.8±14.9degree and 69.2±5.7degree in the E-3 on the each displacement of knee joint. 6. The highest angle of both sides were seen at 171.3±6.9degree and 167.9±8.4degree in the E-3 on the each displacement of ankle joint As a result of these studies, by jumping with ankle joint extension to accomplish the Ring jump action, it is considered to have the time of flexiblity and staying in the air which we can see in a back.

Pain, Depression, Body Mass Index in Conscripts with Chronic Low Back Pain in South Korea

Ju Hwan Lee,Ki Mai Um,Jung San Wang,Sa Gyeom Lee,Joo Hyun Park,Ja Pung Koo,Jung Hee Kim,Suk Hee Lee,Ok Kon Moon 국제물리치료학회 2014 Journal of International Academy of Physical Ther Vol.5 No.1

This study is a cross-sectional study for conscripts with chronic low back pain, where it is designed to investigate general characteristics that conscripts with chronic low back pain carry, and it is also aimed to analyze the correlation as well as discrepancy within pain, depression and body mass index depending on their ranks. In this study, 90 Korean conscripts with chronic low back pain participated. And in order to analyze general characteristics as well as pain, depression and body mass index of the subjects, this study adopted a survey questionnaire upon general characteristics, and it also employed Visual Analogue Scacle(VAS) and Center for Epidemiological Studies Depression(CES-D) Scale which have proven their credibility, where BMI values for the subjects were calculated based on 'Asian Pacific standard' Body Mass Index(BMI). From the general characteristics exhibited by the subjects through this study, average age and average height of the subjects were 20.78±1.41 and 175.97±5.34 respectively; and corporals displayed the highest ratio of 42% with the chronic low back pain while 40% of the total subjects experienced the duration of the illness less than 6 to 9 months. Moreover, 57.8% of all subjects were reportedly suffering moderate pain, and 48% exhibited depression while 49% carried BMI value between 18.5 and 22.9kg/m2(normal range). Based on the analysis of correlation among pain, depression, discrepancy of BMI depending on the ranks and each independent variable, it appears that there is no significant difference amongst the ranks, and there is no correlation between independent variables; however, it was obvious that all groups divided by the ranks had a moderate pain(45-74mm), depression(≥16) and BMI value in normal range(18.5-22.9).

Development of SNP-based CAPS and dCAPS markers in eight different genes involved in starch biosynthesis in rice

Lee, Gi-An,Koh, Hee-Jong,Chung, Hun-Ki,Dixit, Anupam,Chung, Jong-Wook,Ma, Kyung-Ho,Lee, Sok-Young,Lee, Jung-Ro,Lee, Gang-Seob,Gwag, Jae-Gyun,Kim, Tae-San,Park, Yong-Jin Springer-Verlag 2009 Molecular breeding Vol.24 No.1

Pain, Depression, Body Mass Index in Conscripts with Chronic Low Back Pain in South Korea

Lee, Ju Hwan,Um, Ki Mai,Wang, Jung San,Lee, Sa Gyeom,Park, Joo Hyun,Koo, Ja Pung,Kim, Jung Hee,Lee, Suk Hee,Moon, Ok Kon International Academy of Physical Therapy Research 2014 Journal of International Academy of Physical Ther Vol.5 No.1

This study is a cross-sectional study for conscripts with chronic low back pain, where it is designed to investigate general characteristics that conscripts with chronic low back pain carry, and it is also aimed to analyze the correlation as well as discrepancy within pain, depression and body mass index depending on their ranks. In this study, 90 Korean conscripts with chronic low back pain participated. And in order to analyze general characteristics as well as pain, depression and body mass index of the subjects, this study adopted a survey questionnaire upon general characteristics, and it also employed Visual Analogue Scacle(VAS) and Center for Epidemiological Studies Depression(CES-D) Scale which have proven their credibility, where BMI values for the subjects were calculated based on 'Asian Pacific standard' Body Mass Index(BMI). From the general characteristics exhibited by the subjects through this study, average age and average height of the subjects were $20.78{\pm}1.41$ and $175.97{\pm}5.34$ respectively; and corporals displayed the highest ratio of 42% with the chronic low back pain while 40% of the total subjects experienced the duration of the illness less than 6 to 9 months. Moreover, 57.8% of all subjects were reportedly suffering moderate pain, and 48% exhibited depression while 49% carried BMI value between 18.5 and $22.9kg/m^2$(normal range). Based on the analysis of correlation among pain, depression, discrepancy of BMI depending on the ranks and each independent variable, it appears that there is no significant difference amongst the ranks, and there is no correlation between independent variables; however, it was obvious that all groups divided by the ranks had a moderate pain(45-74mm), depression(${\geq}16$) and BMI value in normal range(18.5-22.9).

Predictive Models to Describe Kinetic Behavior of Staphylococcus aureus on Various Cheeses

( Hee Young Lee ),( Soo Min Lee ),( Kyung Mi Kim ),( Soo Yeon Ahn ),( Soon Min Oh ),( Jin San Moon ),( Young Jo Kim ),( Yo Han Yoon ) 대한보건협회 2013 대한보건협회 보건종합학술대회 Vol.2013 No.-

Background: Staphylococcus aureus is an important human pathogen. Sometimes S. aureus is the major causative agent of food-borne disease due to dairy products. Purpose: This study developed mathematical models to describe kinetic behaviors of Staphylococcus aureus on natural and processed cheeses. Methods: Two natural cheeses (Brie and Camembert) and three processed cheeses (Mozzarella, Cheddar, and Gouda) were inoculated with a five-strain mixture of S. aureus at 3-4log CFU/g. The samples were then stored at 4-30℃. Total bacterial and S. aureus cell counts were enumerated on tryptic soy agar and mannitol salt agar, respectively. The growth data of S. aureus from each cheese were fitted to the Baranyi model to calculate maximum specific growth rate (max; log CFU/g/h) and lag phase duration (LPD; h). The kinetic parameters were further analyzed by the square root model as a function of storage temperature. The model performance was validated with observed data, and root mean square error (RMSE) was calculated. Results: S. aureus growth was observed at 10-30℃ for natural cheeses, but the growth of S. aureus on Mozzarella and Cheddar slice cheeses was observed at 15-30℃. S. aureus growth on Gouda slice cheese was observed only at 25 and 30℃. max values were increased, but LPDs were decreased as storage temperature increased. No differences of the maxand LPD values were observed between Brie and Camembert cheeses. S. aureus had lower (P<0.05) growth on processed cheeses than on natural cheeses, especially Gouda slice cheese had the lowest growth of S. aureus. In addition, the prediction of the developed model also showed acceptable performance (RMSE=0.351-0.750). The results indicate that the developed mathematical models should be helpful in exposure assessment S. aureus growth on various cheeses.