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Lei Zhu,Mei Mei Peng,조광연,Shu Ye,Sourav Sarkar,Kefayat Ullah,Ze-Da Meng,오원춘 한국세라믹학회 2013 한국세라믹학회지 Vol.50 No.6
In this study, ZnSe-TiO2 composites were synthesized by a facile hydrothermal-assisted sol-gel process and characterized by nitrogen adsorption isotherms (77 K), X-ray diffraction (XRD), scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) analysis, transmission electron microscopy (TEM) and UV-vis diffuse reflectance spectrophotometry. The photocatalytic activity was investigated by decoloration methylene blue (MB), methyl orange (MO), and rhodamine B (Rh.B) in an aqueous solution under visible light irradiation. The results revealed that the photocatalytic activity of the ZnSe-TiO2 photocatalyst was much higher than that of pureTiO2. The ZnSe nanoparticles, which act as a photosensitizer, not only extend the spectral response of TiO2 to the visible region but also reduce charge recombinations.
Intermedins A and B; New Metabolites from Schisandra propinqua var. intermedia
Hong-Mei Li,Chun Lei,Yong-Ming Luo,Xiao-Nian Li,Xiao-Lei Li,Jian-Xin Pu,San-Yun Zhou,Rong-Tao Li,Han-Dong Sun 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.6
A new dibenzocyclooctadiene lignan, intermedin A (1), and a new natural bisabolane sesquiterpenoid, intermedin B (2), were isolated from the aerial parts of Schisandra propinqua var. intermedia. Their structures were elucidated on the basis of extensive spectroscopical analysis.
Prognostic Value of Vascular Endothelial Growth Factor Expression in Resected Gastric Cancer
Liu, Lei,Ma, Xue-Lei,Xiao, Zhi-Lan,Li, Mei,Cheng, Si-Hang,Wei, Yu-Quan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7
Background and Aims: Vascular endothelial growth factor (VEGF) is a potential prognostic biomarker for patients with resected gastric cancer. However, its role remains controversial. The objective of this study was to conduct a systematic review and meta-analysis of published literature. Methods: Relevant literature was identified using Medline and survival data from published studies were collected following a methodological assessment. Quality assessment of eligible studies and meta-analysis of hazard ratio (HR) were performed to review the correlation of VEGF overexpression with survival and recurrence in patients with gastric cancer. Results: Our meta-analysis included 44 published studies with 4,794 resected patients. VEGF subtype for the prediction of overall survival (OS) included tissue VEGF (HR=2.13, 95% CI 1.71-2.65), circulating VEGF (HR=4.22, 95% CI 2.47-7.18), tissue VEGF-C (HR=2.21, 95% CI 1.58-3.09), tissue VEGF-D (HR=1.73, 95% CI 1.25-2.40). Subgroup analysis showed that HRs of tissue VEGF for OS were, 1.78 (95% CI 0.90-3.51) and 2.31 (95% CI 1.82-2.93) in non-Asians and Asians, respectively. The meta-analysis was also conducted for disease free survival (DFS) and disease specific survival (DSS). Conclusion: Positive expression of tissue VEGF, circulating VEGF, VEGF-C and VEGF-D were all associated with poor prognosis in resected gastric cancer. However, VEGF demonstrated no significant prognostic value for non-Asian populations. Circulating VEGF may be better than tissue VEGF in predicting prognosis.
Zhu, Lei,Peng, Mei-Mei,Cho, Kwang Youn,Ye, Shu,Sarkar, Sourav,Ullah, Kefayat,Meng, Ze-Da,Oh, Won-Chun The Korean Ceramic Society 2013 한국세라믹학회지 Vol.50 No.6
In this study, ZnSe-$TiO_2$ composites were synthesized by a facile hydrothermal-assisted sol-gel process and characterized by nitrogen adsorption isotherms (77 K), X-ray diffraction (XRD), scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) analysis, transmission electron microscopy (TEM) and UV-vis diffuse reflectance spectrophotometry. The photocatalytic activity was investigated by decoloration methylene blue (MB), methyl orange (MO), and rhodamine B (Rh.B) in an aqueous solution under visible light irradiation. The results revealed that the photocatalytic activity of the ZnSe-$TiO_2$ photocatalyst was much higher than that of pure$TiO_2$. The ZnSe nanoparticles, which act as a photosensitizer, not only extend the spectral response of $TiO_2$ to the visible region but also reduce charge recombinations.
Intermedins A and B; New Metabolites from Schisandra propinqua var. intermedia
Li, Hong-Mei,Lei, Chun,Luo, Yong-Ming,Li, Xiao-Nian,Li, Xiao-Lei,Pu, Jian-Xin,Zhou, San-Yun,Li, Rong-Tao,Sun, Han-Dong 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.6
A new dibenzocyclooctadiene lignan, intermedin A (1), and a new natural bisabolane sesquiterpenoid, intermedin B (2), were isolated from the aerial parts of Schisandra propinqua var. intermedia. Their structures were elucidated on the basis of extensive spectroscopical analysis.
Robust anti-icing performance of silicon wafer with hollow micro-/nano-structured ZnO
Lei Wang,Chao Teng,Jing Liu,왕만상,Liu Guicheng,김지영,Qiwen Mei,이중기,Jingxia Wang 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.62 No.-
A novel silicon-based robust anti-icing surface with hollow micro-/nano-structured ZnO (HMN) is investigated. The droplet could not freeze in 30 min under low temperature of −15 °C, while that performance fails on the nano-structured and smooth surfaces. The cooling period of temperature fields on liquid droplet and the base are observed, which indicates that the air layer has a significant effect on the performance of the anti-icing surface. The results prove that the hollow micro-structure layer provides much more air than the nano-structured layer and induces the maximum thermal resistance, leading to its icephobic property. In this finding, HMN provides large thermal resistance between the base and liquid droplet and easily realizes long lasting anti-icing performance under lower temperature. This new concept is expected to be used in the fields of anti-icing, superhydrophobicity, insulation, thermal resistance, etc.
Effect of Sophora flavescens on the pharmacokinetics of carbamazepine in rats
Lei Shi,Xue-Liang Dang,Xin-You Liu,Hua-Mei Wei,Meng-Meng Yang,Yan Zhang 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.12
Carbamazepine (CBZ), an antiepilepticwith narrow therapeutic window, is a substrate ofCYP 3A4 which metabolizes CBZ to carbamazepine-10,11-epoxide (CBZE). CBZE is an active and toxicitymetabolite, and it is a substrate of MRP-2. UsingCBZ for a long time can cause hepatic injury. Sophora flavescens (SF) is a medicinal herb used forthe protected hepatic injury. This study investigatedthe acute and chronic effects of SF on the pharmacokineticsof CBZ in rats. The concentrations of CBZand CBZE in plasma and tissues were determined byHPLC method. The results showed that SF whichsignificantly decreased the AUC0-t of CBZ, increasedCBZE conversely. Tissue analysis showed that theconcentrations of CBZ and CBZE in brain and liverwere decreased by SF. In addition, the distribution ofCBZE in kidney was reduced significantly, whichinfluenced the CBZE excretion and increased the drugtoxic potentially. Results in the current study suggestthat patients using CBZ might be cautioned in the useof SF extract or Sophora-derived products. Meanwhile,patients receiving drugs which are substrates ofCYP 3A4 and/or MRP-2 should be advised of thepotential herb–drug interaction to reduce the risk oftherapeutic failure or increased toxicity of conventionaldrug therapy.
Lei Wan,Ning Zhu,Xuan Li,Rui-ying Zhang,Ting Mei 한국정밀공학회 2016 International Journal of Precision Engineering and Vol.17 No.8
In order to realize the replication of high-quality polymer microstructures with vertical and smooth sidewalls, a gas-assisted hot embossing process with low pressure supplied was optimized to eliminate the swallowtail phenomenon during pattern transfer and simplify workpiece process setting. With help of passive alignment clamp, the rate of replication greater than 95.5% for vertical sidewalls was successfully obtained under the optimum process condition. Accordingly, a root mean square sidewall roughness of 4.6 nm was measured for polymer trenches in comparison with that of 5.7 nm for the silicon mold using a bevel-cut preparation technique. Furthermore, the rate of bulging of less than 15% for polymer workpiece was also obtained. The experiment has demonstrated that high-precise polymer pattern replication is related to both process settings and mold morphology sizes.
Lei Li,Li-Jie Zhang,Ning Zhang,Fei Hu,Yin Jiang,Chun-Yi Xuan,Wei-Mei Jiang 한국풍공학회 2010 Wind and Structures, An International Journal (WAS Vol.13 No.6
A meteorological model, RAMS, and a commercial computational fluid dynamics (CFD) model, FLUENT are combined as a one-way off-line nested modeling system, namely, RAMS/FLUENT system. The system is experimentally applied in the wind simulation over a complex terrain, with which numerical simulations of wind field over Foyeding weather station located in the northwest mountainous area of Beijing metropolis are performed. The results show that the method of combining a meteorological model and a CFD model as a modeling system is reasonable. In RAMS/FLUENT system, more realistic boundary conditions are provided for FLUENT rather than idealized vertical wind profiles, and the finite volume method (FVM) of FLUENT ensures the capability of the modeling system on describing complex terrain in the simulation. Thus, RAMS/FLUENT can provide fine-scale realistic wind data over complex terrains.
Bending ratcheting behavior of pressurized straight Z2CND18.12N stainless steel pipe
Lei Wang,Gang Chen,Jianbei Zhu,Xiuhu Sun,Yunhui Mei,Xiang Ling,Xu Chen 국제구조공학회 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.52 No.6
The ratcheting effect greatly challenges the design of piping components. With the assistance of the quasi-three point bending apparatus, ratcheting and the ratcheting boundary of pressurized straight Z2CND18.12N stainless steel pipe under bending loading and vertical displacement control were studiedexperimentally. The characteristics of progressive inelastic deformation in axial and hoop directions of the Z2CND18.12N stainless steel pipes were investigated. The experiment results show that the ratcheting strainoccurs mainly in the hoop direction while there is less ratcheting strain in the axial direction. Thecharacteristics of the bending ratcheting behavior of the pressure pipes were derived and compared under load control and displacement control, respectively. The results show that the cyclic bending loading and the internal pressure affect the ratcheting behavior of the pressurized straight pipe significantly under loadcontrol. In the meantime, the ratcheting characteristics are also highly associated with the cyclicdisplacement and the internal pressure under displacement control. All these factors affect not only the saturation of the ratcheting strain but the ratcheting strain rate. A series of multi-step bending ratcheting experiments were conducted under both control modes. It was found that the hardening effect of Z2CND18.12N stainless steel pipe under previous cyclic loadings no matter with high or low displacement amplitudes is significant, and the prior loading histories greatly retard the ratcheting strain and its rate under subsequent loadings. Finally, the ratcheting boundaries of the pressurized straight Z2CND18.12N stainless steel pipe were determined and compared based on KTA/ASME, RCC-MR and the experimental results.