Sleep duration and chronic kidney disease: The Korean Genome and Epidemiology Study (KoGES)-Kangwha study

( Hansol Choi ),( Hyeon Chang Kim ),( Joo Young Lee ),( Ju-mi Lee ),( Dong Phil Choi ),( Il Suh ) 대한내과학회 2017 The Korean Journal of Internal Medicine Vol.32 No.2

Background/Aims: Sleep duration affects health in various ways. The objective of this study was to investigate the associations of sleep duration with chronic kidney disease (CKD) in a Korean adult population. Methods: This cross-sectional analysis was conducted for total of 1,360 participants who completed baseline health examinations for the Korean Genome and Epidemiology Study-Kangwha study in 2010 to 2011. Sleep habits were measured by an interviewer-assisted questionnaire. Sleep duration was calculated based on the number of hours per day participants had slept over the past 1 year. CKD was defined as either proteinuria or estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m². Multiple logistic regression models were applied to examine associations between sleep duration and CKD. Results: Women with very long sleep duration (≥ 9 hours/day) were at significantly increased odds for having high serum creatinine (odds ratio [OR], 2.936; 95% confidence interval [CI], 1.176 to 7.326), low eGFR (OR, 3.320; 95% CI, 1.372 to 8.034), and CKD (OR, 3.112; 95% CI, 1.315 to 7.363), compared those with a typical sleep duration (7 to < 8 hours/day), after adjusting for sociodemographic status, socioeconomic status, health behaviors, comorbidities, and sleep quality. Among women, for every 1 hour increase in sleep duration per day, there was a 24.6% increase in the presence of CKD (OR, 1.246; 95% CI, 1.019 to 1.523). However, among men, sleep duration was not significantly associated with CKD. Conclusions: Very long sleep duration was independently associated with a higher prevalence of CKD among Korean women. Gender may influence this associa-tion.

The Predictive Values of Lesion Size, F-18 FDG Avidity and I-131 Avidity for the Clinical Outcome of I-131 Treatment in Patients with Metastatic Differentiated Thyroid Carcinoma Only in the Lung

Choi, Joon Ho,Byun, Byung Hyun,Lim, Ilhan,Moon, Hansol,Park, Jihyun,Chang, Kyoung Jin,Kim, Byung Il,Choi, Chang Woon,Lim, Sang Moo 대한핵의학회 2018 핵의학 분자영상 Vol.52 No.2

Purpose We aimed to evaluate the prognostic values of radiography, F-18 FDG PET, and I-131 whole body scans in patients with lung-only metastasis from differentiated thyroid carcinoma (DTC). Methods Between 1998 and 2013, we included 31 patients (F: 26, M: 5) with lung-only metastasis from DTC who had been treated with I-131 and underwent PET. Lung metastasis was categorized according to the size (macronodular ${\geq}1.0cm$ vs. micronodular <1.0 cm), FDG avidity (avid vs. non-avid), and I-131 avidity (avid vs. non-avid). Progression-free survival (PFS) was evaluated for each patient. Results Among 31 patients, seven (23%) had macronodular lung metastasis, 26 (84%) had FDG avid lung metastasis, and 16 (52%) had I-131 avid lung metastasis. During the median follow-up period of 9.4 y, median PFS was 6.1 y. Based on Kaplan-Meier analysis, macronodular lung metastasis (p = 0.017) and I-131 non-avid lung metastasis (p = 0.059) were significantly associated with worse outcomes, but FDG avid lung metastasis was not (p = 0.135). Patients with FDG non-avid lung metastasis did not experience disease progression during follow-up, while 11 of 26 patients (42%) experienced disease progression. Based on univariate analysis, the hazard ratio for a poor prognosis was 3.78 (p = 0.029) for macronodular lung metastasis and 3.29 (p = 0.079) for I-131 non-avid lung metastasis. Conclusions Macronodular and I-131 non-avid lung metastasis were associated with a poor prognosis in lung-only metastasis from DTC. Although FDG avid lung metastasis may be associated with a poor prognosis, a larger-scale study is needed.

Comparison of Formulas for Calculating Low-density Lipoprotein Cholesterol in General Population and High-risk Patients with Cardiovascular Disease

Hansol Choi,심지선,Myung Ha Lee,Young Mi Yoon,Dong Phil Choi,김현창 대한심장학회 2016 Korean Circulation Journal Vol.46 No.5

Background and Objcetives: Low-density lipoprotein cholesterol (LDL-C), an established cardiovascular risk factor, can be generally determined by calculation from total cholesterol, high-density lipoprotein cholesterol, and triglyceride concentrations. The aim of this study was to compare LDL-C estimations using various formulas with directly measured LDL-C in a community-based group and hospital-based group among the Korean population. Subjects and Methods: A total of 1498 participants were classified into four groups according to triglyceride concentrations as follows: <100, 100–199, 200–299, and ≥300 mg/dL. LDL-C was calculated using the Friedewald, Chen, Vujovic, Hattori, de Cordova, and Anandaraja formulas and directly measured using a homogenous enzymatic method. Pearson’s correlation coefficients, intraclass correlation coefficients (ICC), Passing & Bablok regression, and Bland-Altman plots were used to evaluate the performance of six formulas. Results: The Friedewald formula had the highest accuracy (ICC=0.977; 95% confidence interval 0.974-0.979) of all the triglyceride ranges, while the Vujovic formula had the highest accuracy (ICC=0.876; 98.75% confidence interval 0.668–0.951) in people with triglycerides ≥300 mg/dL. The mean difference was the lowest for the Friedewald formula (0.5 mg/dL) and the percentage error was the lowest for the Vujovic formula (30.2%). However, underestimation of the LDL-C formulas increased with triglyceride concentrations. Conclusion: The accuracy of the LDL-C formulas varied considerably with differences in triglyceride concentrations. The Friedewald formula outperformed other formulas for estimating LDL-C against a direct measurement and the Vujovic formula was suitable for hypertriglyceridemic samples; it could be used as an alternative cost-effective tool to measure LDL-C when the direct measurement cannot be afforded.

Protein Cage Nanoparticles as Delivery Nanoplatforms

Choi, Bongseo,Kim, Hansol,Choi, Hyukjun,Kang, Sebyung Kluwer Academic Publishers 2018 Advances in Experimental Medicine and Biology Vol.1064 No.-

Effect of Blueberry Wine on Fats and Fat-soluble Vitamins of Abdominal Fat Depots in Rats

Hansol Choi,Juyeon Kim,Joonghyeap Park,Sang Kyu Noh 한국식품영양과학회 2013 한국식품영양과학회 학술대회발표집 Vol.2013 No.11

Use of Menstrual Sanitary Products in Women of Reproductive Age: Korea Nurses’ Health Study

Choi Hansol,Lim Nam-Kyoo,Jung Heeja,Kim Oksoo,Park Hyun-Young 질병관리본부 2021 Osong Public Health and Research Persptectives Vol.12 No.1

Objectives The use of menstrual hygiene products and its effect on women’s health remains under studied. Patterns of menstrual hygiene product use and the rationale behind choices among Korean women aged 18–45 years were examined. Methods This cross-sectional study was a part of the Korea Nurses’ Health Study. A total of 20,613 nurses participated, and 8,658 nurses participated in Module 7 which included a menstrual hygiene products-related survey. The data were collected through the mobile survey using a self-reported questionnaire. Participants’ use of menstrual hygiene products and related characteristics were analyzed using frequency (percentage) or mean (SD). Results The most common types of menstrual hygiene products across all age groups were disposable menstrual pads (89.0%), followed by cloth menstrual pads (4.5%), tampons (4.2%), and only 1.6% used a menstrual cup. Disposable menstrual pads were the most common across all age groups, but in those aged under 30 years this was followed by tampon use (6%). The most important criteria when choosing a menstrual hygiene product was comfort for disposable menstrual pads (31.3%) and tampons (41.5%), natural ingredients or organic products for cloth menstrual pads (51.4%), and custom fit for the menstrual cup (50.7%). However, for all menstrual hygiene products (except cloth menstrual pads), there was a higher proportion of anxiety than perception of safety, and low awareness of toxic shock syndrome. Conclusion It is important for women to use menstrual hygiene products with confidence. More research is needed to better understand potential health effects of menstrual hygiene products.

셀룰로오스/커피찌꺼기 홀로셀룰로오스 겔의 특성 분석

최한솔(Hansol Choi),양지욱(Jiwook Yang),변지희(JiHui Byeon),황교정(Kyojung Hwang),김대영(Dae-Young Kim) 한국펄프·종이공학회 2021 한국펄프·종이공학회 학술발표논문집 Vol.2021 No.4

왜 사람들은 보는 게임에 열광하는가? : 목표지향적 행동모형에 기반한 온라인 게임 영상 시청 연구

최한솔(Choi, Hansol),이혜미(Lee, Hyemi) 한국소비문화학회 2021 소비문화연구 Vol.24 No.1

‘보는’ 게임을 즐기는 소비자의 증가는 게임 사업과 시장에 많은 변화를 일으켰다. 국내외 기업들이 앞다투어 게임 전문 방송 플랫폼을 출시하면서 보는 게임의 온라인 게임 시장 점유율은 더욱 급속히 확대되고 있다. 보는 게임은 더 이상 ‘하는’ 게임에 부속된 부차적 행위라기보다는 소비자들에게 그 자체로 향유되는 독립적 문화실천으로서의 지위를 갖게 된 것이다. 그러나 보는 게임의 달라진 위상에도 불구하고, 이를 반영한 연구는 현저히 적다. 본 연구는 소비자들이 왜 보는 게임에 열광하는지, 어떠한 요인들이 게임 보기 행동에 유의미한 영향을 미치는지 심도 있게 살펴보고자 하였다. 이를 위해 소비자들의 동기적, 감정적, 인지적, 습관적 요인을 모두 고려한 목표지향적 행동모형을 활용하되, 태도의 선행요인으로서 동기 요인들과 주관적 규범 대신 세분화된 사회적 동조 변인들을 추가하였다. 298명의 조사 참여자들의 응답을 분석한 결과, 조사 참여자들은 실시간 게임 방송보다 편집된 영상을 훨씬 많이 시청하고 있었고, 게임 테크닉 등 정보를 얻기 위한 동기보다는 흥미 동기나 스트리머나 다른 소비자들과의 온라인 상호작용으로 인해 보는 게임에 대해 긍정적 태도를 갖는 것으로 나타났다. 또한, 게임 시청 의도의 중요 설명 변인인 열망은 사회적 동조 변인을 제외한 태도, 지각된 행동 통제, 긍정 및 부정적 기대 정서의 영향을 받는 것으로 나타났다. 시청의도는 과거 시청 빈도와 열망의 직접적 영향을 받는 한편, 흥미와 온라인 상호작용이 태도와 열망을 매개로 간접 효과를 갖고 있었고, 태도, 지각된 행동통제, 긍정 및 부정적 기대 정서가 열망을 매개로 간접 효과를 갖는 것으로 확인되었다. 이러한 결과를 종합할 때, 보는 게임은 기존 온라인 게임에 관한 선행연구들이 또래문화 등 오프라인 상의 규범적 영향력을 강조하였던 것과 달리, 게임 영상 콘텐츠에 대한 흥미나 익명의 타인들과의 온라인 상호작용 등이 보다 중시되는 개인화된 즐거움이자 놀이문화로 정착해가고 있음을 알 수 있었다. The purpose of the current study is to examine various factors which affect online video game watching behavior by applying the model of goal-directed behavior (MGB) as a theoretical framework. There were 298 valid participants used for the final analysis. The results showed that online interaction and entertainment factors significantly influenced attitude toward online video game watching behavior. Furthermore, attitude, perceived behavioral control, positive anticipated emotions, and negative anticipated emotions were significant predictors of the desire to watch online video games. Moreover, desire and frequency of past behavior had a significant effect on intentions to watch online video games. In addition, the results showed that attitude and desire had a mediating effect on intentions to watch online video games. This study provides theoretical implications that online video game watching behavior has been rooted as a personalized leisure practice.

JEM 부호화 속도 향상을 위한 고속 CU 결정 방법

최한솔(Hansol Choi),이종석(Jongsoek Lee),이스마일(Ismail Marzuki),박시내(Seanae Park),심동규(Donggyu Sim) 한국방송·미디어공학회 2018 한국방송공학회 학술발표대회 논문집 Vol.2018 No.6

2모터 2변속기가 장착된 전기구동 자동차의 작동모드 및 모터토크 제어를 통한 에너지 최적화

김한솔(Hansol Kim),최원석(Wonseok Choi),최우석(Wooseok Choi),임원식(Wonsik Lim) 한국자동차공학회 2021 한국 자동차공학회논문집 Vol.29 No.5

A study was conducted to optimize the energy of an electric vehicle equipped with a two-motor and two-transmission system. Since different transmissions are applied to each motor, the speed and torque of the motor vary according to the gear ratio of each transmission. In the two-motor two-transmission system, it was confirmed that the efficiency characteristics of the motor vary not only with the gear stage but also with the torque distribution ratio of the motor. In this study, the optimum gear ratio and motor torque ratio were determined according to various driving conditions. The optimum operating mode of the power train system was obtained. WHVC and JE05 cycles were simulated using the analysis model. It was confirmed that power consumption was reduced by 4.1 % to 6.1 % compared to when the two motor torques were controlled equally using the optimization control.