간호대학생을 위한 의사소통 능력 증진 프로그램의 효과

한미화(Han, Mihwa),이경희(Lee, Kyunghee) 한국간호교육학회 2017 한국간호교육학회지 Vol.23 No.1

Purpose: This study evaluated the efficacy of a communication ability enhancement program for nursing students in Korea through a systematic review of literature and meta-analysis. Methods: The researchers searched data-bases, including the Data Base Periodical Information Academic, Research Information Sharing Service, National Digital Science Library and National Assembly Library. The key words used included ‘communication’ and ‘nursing student’. The researchers evaluated articles published up to July 2016. Out of 381 selected articles, 20 clinical trial studies were meta-analyzed. Each article was evaluated in accordance with the Checklist of Scottish Intercollegiate Guideline Network. The effect size of communication ability, self-efficacy and interpersonal relations were synthesized by a random effects model from analysis software (R 3.2.3). The heterogeneity of effect size was analyzed by exploratory and confirmatory moderator analysis. Results: The overall effect size of the program was of a moderate level (SMD=0.78, 95% CI: 0.49~1.07) along with each outcome of self-efficacy (SMD=0.80, 95% CI: 0.23~1.37), and interpersonal relations (SMD=0.47, 95% CI: 0.14~0.80). For heterogeneity, moderator analysis was performed, by grade, and a statistically significant moderator was found. Conclusion: It is evident that a communication ability enhancement program for nursing students is moderately effective in improving communication ability, self-efficacy and interpersonal relations.

보건계열 대학생의 스마트폰 과다사용과 대학생활 스트레스, 감성지능, 행복감의 관련성

한미화(Han, Mihwa),이경희(Lee, Kyunghee),최현아(Choi, Hyun-A),현진숙(Hyun, Jin-Sook) 계명대학교 간호과학연구소 2015 계명간호과학 Vol.19 No.1

Purpose: As the usage of smartphones becomes universalized, consequent social influences have been appearing diversely. This study was conducted to provide basic and relevant data in developing preventive intervention program of smartphone overuse by determining the frequency of smartphone usage of college students in Health-related department and its influences in relation to frequency. Method: To determine the factors influencing college senior students’ smartphone overuse, 367 college senior students in G Province were selected. Categorizing the top 25% of smartphone over users as the high frequency group and the low 25% as the low frequency group, the differences between the two groups regarding general characteristics, college life stress, emotional intelligence and happiness were analyzed. Result: Compared with the low frequency group, the high frequency group smartphone usage was a high priority (p=<.001) in their daily living. Text messaging was more frequent, and the stress level was notably high (Explanatory Power, 81.7%) regarding their study (p=.034), future &employment (p=.023). Conclusion: College students’ smartphone overuse was highly relevant with the level of stress in their college life. Therefore, development of preventive intervention program is recommended

RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in <i>Caenorhabditis elegans</i>

Seo, Mihwa,Seo, Keunhee,Hwang, Wooseon,Koo, Hee Jung,Hahm, Jeong-Hoon,Yang, Jae-Seong,Han, Seong Kyu,Hwang, Daehee,Kim, Sanguk,Jang, Sung Key,Lee, Yoontae,Nam, Hong Gil,Lee, Seung-Jae V. National Academy of Sciences 2015 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.112 No.31

<P><B>Significance</B></P><P>RNA helicases are a large family of enzymes that regulate the generation and maintenance of RNA. However, the physiologic roles of RNA helicases in animal aging remained unknown. Here we show that an RNA helicase, helicase 1 (HEL-1), extends the lifespan of the roundworm <I>Caenorhabditis elegans</I> by up-regulating the longevity transcription factor forkhead box O (FOXO). Our finding suggests that an RNA helicase can have rather specific roles in animal longevity. A number of studies show that variants of FOXO are linked to human aging and longevity. In addition, the mammalian HEL-1 homolog has been implicated in cellular aging. Thus, our work may have direct implications in mammalian aging, and the human HEL-1 homolog may work with FOXO to increase lifespan.</P><P>The homeostatic maintenance of the genomic DNA is crucial for regulating aging processes. However, the role of RNA homeostasis in aging processes remains unknown. RNA helicases are a large family of enzymes that regulate the biogenesis and homeostasis of RNA. However, the functional significance of RNA helicases in aging has not been explored. Here, we report that a large fraction of RNA helicases regulate the lifespan of <I>Caenorhabditis elegans</I>. In particular, we show that a DEAD-box RNA helicase, helicase 1 (HEL-1), promotes longevity by specifically activating the DAF-16/forkhead box O (FOXO) transcription factor signaling pathway. We find that HEL-1 is required for the longevity conferred by reduced insulin/insulin-like growth factor 1 (IGF-1) signaling (IIS) and is sufficient for extending lifespan. We further show that the expression of HEL-1 in the intestine and neurons contributes to longevity. HEL-1 enhances the induction of a large fraction of DAF-16 target genes. Thus, the RNA helicase HEL-1 appears to promote longevity in response to decreased IIS as a transcription coregulator of DAF-16. Because HEL-1 and IIS are evolutionarily well conserved, a similar mechanism for longevity regulation via an RNA helicase-dependent regulation of FOXO signaling may operate in mammals, including humans.</P>

실험을 통한 802.11b Wireless LAN 의 성능평가

김미화(Mihwa Kim),한성원(Sungwon Han),염익준(Ikjun Yeom) 한국통신학회 2004 한국통신학회 학술대회 및 강연회 Vol.2004 No.4

A Structural Model of Commitment to Organizational Change in Clinical Nurses

Hong, Mihwa,Han, Sujeong 한국간호과학회 2023 한국간호과학회 학술대회 Vol.2023 No.11

임상간호사의 의사소통 능력과 돌봄 행위의 관계에서 공감 역량의 매개효과

홍미화(Hong, Mihwa),한수정(Han, Sujeong) 기본간호학회 2021 기본간호학회지 Vol.28 No.4

Purpose: This study was done to identify the mediating effect of compassion competence on the relationship between communication competence and caring behavior in clinical nurses. Methods: A structured self-report questionnaire was used to measure caring behavior, communication competence, and compassion competence. During September 2019, data were collected from 170 nurses working at general hospitals. Data were analyzed using hierarchical multiple linear regression with SPSS for Windows version 23.0 and Hayes’s SPSS process macro (version 3.5). Results: Communication skills (β=.52) and compassion ability (β=.77) were identified as important predictors of nurses’ caring behavior. These variables explained approximately 54% of the variance in nurses’ caring behavior. Compassion competence also had a total mediating effect on the relationship between communication competence and caring behavior. Conclusion: In order to enhance the caring behavior of clinical nurses, enhancing compassion competence by strengthening communication development should be considered as a strategy.

적색식용색소인 아마란스의 약동학 특성 및 위장관 투과도 연구

한유진(Youjin Han),구수현(Soo Hyeon Goo),남소정(So Jeong Nam),강윤주(Yun Ju Kang),권미화(Mihwa Kwon),송임숙(Im-Sook Song) 한국생명과학회 2017 생명과학회지 Vol.27 No.7

적색 아조류 타르색소인 아마란스는 인공식용색소로 식품, 화장품, 의약품에 광범위하게 사용되고 있음에도 불구하고, 경구로 복용하였을 때 위장관 흡수율이나 흡수특성에 대해 연구된 바가 없다. 본 연구의 목적은 아마란스의 정맥투여 또는 경구 투여 후 약동학 특성을 평가하고 diffusion chamber system을 이용하여 위장관 흡수율 및 투과도를 평가하고자 하였다. 정맥투여된 아마란스는 38.8분의 소실반감기로 빠르게 혈중에서 소실된다. 그러나 경구투여된 아마란스는 생체이용률도 55.6%로 높은 위장관 흡수율을 나타내며 408분까지 혈중농도가 증가하고 24시간까지 혈중에 남아있는 특성을 나타내었다. 이는 아마란스의 위장관 흡수가 오랫동안 지속적으로 일어나는 것을 의미한다. 이를 확인하기 위하여 소장의 흡수부위를 공장, 회장사부, 회장하부로 나누어 위장관 투과도를 평가하고 투과성이 잘 알려진 지표물질과 비교하였다. 연구결과 아마란스의 위장관투과성은 투과도가 매우 높은 caffeine의 1/3정도의 투과도를 보이고, 중등도의 투과도를 보이는 atenolol과 유사한 투과도를 나타내었으며 회장상부에서의 투과도가 가장 높았다. 결과를 종합하면, 아마란스는 경구투여된 뒤 지속적으로 흡수되며 흡수율도 50% 이상을 보이므로, 식품, 립케어 화장용품, 경구용 의약품에 아마란스 등의 색소가 포함될 경우에는 첨가량 등을 고려하여 신중하게 사용해야 할 것이다. Although amaranth, a red-colored tar dye, is usually used in foods, cosmetics, and pharmaceutics, its bioavailability and intestinal absorption have not previously been investigated. Therefore, the purpose of this study was to investigate the pharmacokinetics properties and intestinal permeability of amaranth in rats following the intravenous and oral administration of this dye. Amaranth rapidly disappeared from the plasma following the intravenous injection, with a half-life of 38.8 minutes. However, the plasma concentration of amaranth was increased to 400 minutes following the oral administration of amaranth, and the absorption time and bioavailability of amaranth were calculated to be 356 minutes and 55.6%, respectively. This suggests that once amaranth exists in the gut, this dye may be efficiently and effectively absorbed. Consistent with this result, the intestinal permeability of amaranth was comparable to atenolol, a marker compound of moderate permeability, and to one-third of caffeine’s intestinal permeability (a highly permeable compound). In conclusion, a significantly long absorption time and substantial intestinal absorption of amaranth was observed following the oral administration of amaranth at a dose of 300 mg/kg in rats, despite the rapid elimination of this dye from the plasma. These results may suggest the necessity of a careful and limited use of amaranth dye when it is added to food, lip-care cosmetics, and orally administered pharmaceutics.

Validity and Reliability of Metacognitive Rating Scale for Nursing Students

( Lee¸ Kyunghee ),( Heo¸ Youngjin ),( Han¸ Mihwa ),( Kim¸ Mijung ),( Choi¸ Hyunseok ) 한국정신간호학회 2021 정신간호학회지 Vol.30 No.3

Purpose: The aim of this study was to determine the reliability and validity of the metacognition rating scale (MCRS), which is a revised version of the existing metacognition questionnaire (MCQ) with anger and anxiety added. Methods: A survey was conducted on 591 nursing students at colleges in North and South Gyeongsang Provinces, South Korea. The collected data were processed for the reliability and validity of the MCRS through Cronbach’s α and confirmatory factor analysis using SPSS 26.0. Results: Cronbach’s α for the reliability of MCRS was calculated at .88, .86, .77, .74, and .66 for five subfactors. Among the five subfactors, the first, second, third, and fifth factors showed high correlation in each of six items. Factor 4 was highly correlated in 5 out of 6 questions. Conclusion: The data confirm that the MCQ revised to include anger and anxiety is both reliable and valid for nursing students. Therefore, this scale can be used to identify the maladaptive metacognition of nursing students in stressful situations.

개발밀도와 아파트 가격의 비선형적 관계 탐색: 개발밀도와 아파트 가격의 비선형적 관계 탐색

서정석(Jungseok Seo),임미화(Mihwa Lim),한상욱(Sanguk Han),Sri Utami Purwaningati(Sri Utami Purwaningati ),김정섭(Jeongseob Kim) 한국주택학회 2023 주택연구 Vol.31 No.2

Willingness to use smartphone apps for lifestyle management among patients with schizophrenia

Lee, Kyunghee,Bejerano, Ivy Lynne,Han, Mihwa,Choi, Hyun Seok Elsevier 2019 Archives of psychiatric nursing Vol.33 No.4

<P><B>Abstract</B></P> <P>Mobile technology is a popular intervention mode for patients with schizophrenia because of its accessibility and functionality. We examined patients' willingness to use smartphone apps for lifestyle management and its effect on self-reported lifestyle habits. Five hundred fifty-five inpatients from various mental health institutions participated. Willingness to use smartphone apps was associated with age, education, income, device type, and body mass index. Positive opinions on smartphone app use were significantly associated with willingness to use apps, which was significantly associated with dietary and living habits. Thus, improving willingness to use apps can help patients improve their lifestyle, potentially preventing relapse.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Positive opinions toward smartphone apps can improve app use willingness. </LI> <LI> App use willingness may improve lifestyle in schizophrenia patients. </LI> <LI> Dietary habits appear to improve with patients' willingness. </LI> <LI> Living habits appear to improve with patients' willingness. </LI> </UL> </P>