Yet another Hybrid Strategy for Auto-tuning SpMV on GPUs

Zhaohui Wang,Xiaojie Qiu,Aimin Zhang,Yichao Cheng,Yi Peng,Sun Sun 보안공학연구지원센터 2015 International Journal of Software Engineering and Vol.9 No.5

Sparse matrix-vector multiplication (SpMV) is a key linear algebra algorithm and is widely used in many application domains. Besides multi-core architecture, there is also extensive research focusing on accelerating SpMV on many-core Graphics Processing Units (GPUs). SpMV computations have many indirect and irregular memory accesses, and load imbalance could occur while mapping computations onto single-instruction, multiple-data (SIMD) GPUs. SpMV is highly memory bandwidth-bound, though GPUs have massive computational resources, the performance of SpMV on GPUs is still unsatisfying. In this paper, we present a new hybrid strategy for auto-tuning SpMV on GPUs. Our strategy combines the advantages of row-major storage and column-major storage. Like many other strategies, we reordered a given sparse matrix according to row lengths in decreasing order. In order to be more adaptive and efficient, we proposed a new hybrid Blocked CSR and JDS (BCJ) format based on original CSR and JDS. BCJ splits a sparse matrix into a denser part and a sparser part after reordering and uses different kernels to process the corresponding part. And we proposed corresponding auto-tuning framework to help transforming matrix and launching kernels according to the sparsity characteristics of the matrix. A CUDA implementation of BCJ outperforms the original formats significantly on a broad range of unstructured sparse matrices.

Microarrays for the Detection of HBV and HDV

Sun, Zhaohui,Zheng, Wenling,Zhang, Bao,Shi, Rong,Ma, Wenli Korean Society for Biochemistry and Molecular Biol 2004 Journal of biochemistry and molecular biology Vol.37 No.5

The increasing pace of development in molecular biology during the last decade has had a direct effect on mass testing and diagnostic applications, including blood screening. We report the model Microarray that has been developed for Hepatitis B virus (HBV) and Hepatitis D virus (HDV) detection. The specific primer pairs of PCR were designed using the Primer Premier 5.00 program according to the conserved regions of HBV and HDV. PCR fragments were purified and cloned into pMD18-T vectors. The recombinant plasmids were extracted from positive clones and the target gene fragments were sequenced. The DNA microarray was prepared by robotically spotting PCR products onto the surface of glass slides. Sequences were aligned, and the results obtained showed that the products of PCR amplification were the required specific gene fragments of HBV, and HDV. Samples were labeled by Restriction Display PCR (RD-PCR). Gene chip hybridizing signals showed that the specificity and sensitivity required for HBV and HDV detection were satisfied. Using PCR amplified products to construct gene chips for the simultaneous clinical diagnosis of HBV and HDV resulted in a quick, simple, and effective method. We conclude that the DNA microarray assay system might be useful as a diagnostic technique in the clinical laboratory. Further applications of RD-PCR for the sample labeling could speed up microarray multi-virus detection.

Screening nephroprotective compounds from cortex Moutan by mesangial cell extraction and UPLC

Min Sun,Limei Huang,Jianliang Zhu,Wenjie Bu,Jing Sun,Zhaohui Fang 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.6

A method for screening nephroprotective compoundsin cortex Moutan, a common traditional Chinesemedicine (TCM) in treating diabetic nephropathy with renalmesangial cell extraction and ultra performance liquidchromatography technique was described in this paper. Wehypothesize that the compounds which bind to cell membranesunder pathological conditions may be the bioactivecompounds in TCMs. Mesangial cells were cultured inmedium containing 5 mM (physiological, NG) or 30 mM(pathological, HG) glucose for 48 h and then incubated withcortex Moutan extract. After the unbound substances werewashed off, the cell membrane-bound compounds weredissociated and concentrated by an SPE column. By comparingthe chromatograms of NG and HG cultured-cellextractions and cortex Moutan extract, three compoundsbound to both NG and HG-cultured mesangial cells wereidentified as paeoniflorin, pentagalloylglucose (PGG) andpaeonol. In vitro studies showed that paeoniflorin, PGG andpaeonol reduced the activity of nicotinamide-adenine dinucleotidephosphate oxidase (NADPH) activity, anddecreased the level of reactive oxygen species (ROS),transforming growth factor-b1 (TGF-b1) and fibronectin inhigh glucose cultured mesangial cells. The results indicatethat paeonol, paeoniflorin and PGG may be the nephroprotectivecompounds from cortex Moutan. This study isexpected to provide a more reliable and effective method forscreening bioactive compounds from the complex TCM systems.

A Load Compensator Based on One-Cycle Control with Plug-In Repetitive Control

Jian Hu,Zhaohui Sun,Hao Ma,Guozhu Chen 전력전자학회 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.2

This study proposes a novel one-cycle control scheme with a plug-in repetitive controller for load compensator. The novelty of this scheme lies in the combination of high dynamics and the simplicity of a one-cycle controller and good steady-state harmonic suppression ability of the repetitive controller. In addition, the proposed scheme can reduce the effect of the harmonics in phase voltage for the existence of the repetitive controller. Finally, experimental results on a three-phase, four-wire, three-level load compensator are reported to validate the effectiveness of the proposed control scheme.

High-Performance Solution-Processed Non-Fullerene Organic Solar Cells Based on Selenophene-Containing Perylene Bisimide Acceptor

Meng, Dong,Sun, Dan,Zhong, Chengmei,Liu, Tao,Fan, Bingbing,Huo, Lijun,Li, Yan,Jiang, Wei,Choi, Hyosung,Kim, Taehyo,Kim, Jin Young,Sun, Yanming,Wang, Zhaohui,Heeger, Alan J. American Chemical Society 2016 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.138 No.1

<P>Non-fullerene acceptors have recently attracted tremendous interest because of their potential as alternatives to fullerene derivatives in bulk heterojunction organic solar cells. However, the power conversion efficiencies (PCEs) have lagged far behind those of the polymer/fullerene system, mainly because of the low fill factor (FF) and photocurrent. Here we report a novel perylene bisimide (PBI) acceptor, SdiPBI-Se, in which selenium atoms were introduced into the perylene core. With a well-established wide-band-gap polymer (PDBT-T1) as the donor, a high efficiency of 8.4% with an unprecedented high FF of 70.2% is achieved for solution-processed non-fullerene organic solar cells. Efficient photon absorption, high and balanced charge carrier mobility, and ultrafast charge generation processes in PDBT-T1:SdiPBI-Se films account for the high photovoltaic performance. Our results suggest that non-fullerene acceptors have enormous potential to rival or even surpass the performance of their fullerene counterparts.</P>

A Load Compensator Based on One-Cycle Control with Plug-In Repetitive Control

Hu, Jian,Sun, Zhaohui,Ma, Hao,Chen, Guozhu The Korean Institute of Power Electronics 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.2

This study proposes a novel one-cycle control scheme with a plug-in repetitive controller for load compensator. The novelty of this scheme lies in the combination of high dynamics and the simplicity of a one-cycle controller and good steady-state harmonic suppression ability of the repetitive controller. In addition, the proposed scheme can reduce the effect of the harmonics in phase voltage for the existence of the repetitive controller. Finally, experimental results on a three-phase, four-wire, three-level load compensator are reported to validate the effectiveness of the proposed control scheme.

Coloration of Calcium Alginate Fiber with Dye and Auxiliary Derived from Polyvinylamine (PVAm). I. Complex Dyeing with Polymeric Dyes Containing PVAm

Zhaoyi Li,Liang Sun,Zhongjun Fu,Yuchao Li,Zhaohui Jiang,Bingtao Tang,Quan Ji,Yanzhi Xia,Ming Wang,Haofei Huang 한국섬유공학회 2021 Fibers and polymers Vol.22 No.3

Calcium alginate fiber is a biomaterial with promising application in textile industry. However, the poor dyeingproperty of this fiber restricts its development. In this study, three PVAm (polyvinylamine) dyes were applied to the exhaustdyeing of calcium alginate fiber and their dyeing behavior under different dyeing conditions was studied. The dyeing resultsrevealed that PVAm dyes were firmly adsorbed on calcium alginate fiber by coordination bonding formed between theprimary amino groups in PVAm backbones of dyes and Ca2+ ions in calcium alginate fiber. This special complex dyeingmode was further confirmed by a Langmuir-type adsorption manner of PVAm-1 dye for calcium alginate fiber. By theformation of this stable chelation structure between dyes and fibers, high exhaustion rates (88.9-97.1 %) and excellent colorfastness were obtained. SEM and XRD results also showed that the surface and crystal phase of dyed fibers had very slightchanges compared to those of original calcium alginate fibers. The strength property of the fiber was also maintained wellafter this special complex dyeing process.

A Review of Non-Isolated High Step-Down Dc-Dc Converters

Ajmal Farooq,Zeeshan Malik,Zhaohui Sun,Guozhu Chen 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.8

In this paper, a review of the common techniques used for high step-down dc-dc voltage conversion is presented. First, the limitations of conventional buck & synchronous rectifier buck converters used for high step down dc-dc voltage conversion which include narrow duty cycle, high voltage stress, large ripple and low efficiency are briefly discussed. Then various topologies of non-isolated step-down dc-dc converters are reviewed and discussed. The topologies/techniques used for high step down dc-dc conversion are divided into various groups which include interleaved, quadratic, tapped, switched capacitor, switched inductor, coupled inductor, multi level and buck converter with three state switching cells. Each group of converters is briefly discussed, main circuit structure of each topology is given and their features and limitations are given. Finally a comparison of all the discussed topologies is carried out based on some common features.

Clinicopathological and molecular characterization of high-grade endometrial carcinoma with POLE mutation: a single center study

Shuangni Yu,Zezheng Sun,Liju Zong,Jie Yang,Mei Yu,Jie Chen,Zhaohui Lu 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.3

Objective: The molecular classification system of endometrial carcinoma (EC) in ‘The Cancer Genome Atlas’ is widely acknowledged for its prognostic utility. Subsequently, more simplified classification system that incorporate DNA polymerase epsilon (POLE) exonuclease domain mutations, mismatch repair deficiencies (MMRd), and abnormal p53 (P53abn) has also demonstrated its clinical utility. These classifications helped identifying a ‘POLE ultramutated’ (POLEmut) category of patients, most of whom show excellent prognoses despite having high-grade ECs. We aimed to investigate the clinicopathological and molecular characteristics of high-grade ECs with POLEmut. Methods: We investigated 414 patients with high-grade ECs (including endometrioid carcinomas grade 3, serous carcinomas, clear cell carcinomas, mixed carcinomas, undifferentiated and dedifferentiated carcinomas, and carcinosarcomas) by sequencing and immunohistochemical staining. Results: Forty-three tumors (10.4%) were classified as POLEmut, including 2 with new, possibly pathogenic POLE mutations at P286C and L424V. These patients had very good prognoses except for 1 with stage IV disease and residual tumor. Eleven patients in this group also had P53abn and 4 had MMRd; molecular analysis revealed that patients with synchronous POLE pathogenic mutation and other mutations had a POLEmut or MMRd phenotype; survival analysis found no difference in prognosis between these patient categories. The prognoses of patients in the POLEmut EC group were not significantly influenced by treatment or risk category. Conclusions: Patients with high-grade EC exhibiting POLEmut have very good clinical outcomes, and should be identified urgently in daily work owing to their conflicting morphology. Our findings also provide guidance on subclassifying ECs with poor histological appearance.

Laboratory and field evaluation of the repellency of six preservatives to red imported fire ants (Hymenoptera: Formicidae)

Wenquan Qin,Hongpeng Xiong,YuzhenWen,XiujunWen,HuiWang,Yihan Fang,TaoMa,Zhaohui Sun,Xiaoyang Chen,Cai Wang 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.2

Baiting is widely applied for the detection and control of the red imported fire ants, Solenopsis invicta Buren. Adding preservatives into baits would prevent microbial contamination during production and storage, and might extend period of bait attractiveness in the field. However, it is not known if preservatives are repellent to S. invicta. In the present study, potential effects of six commonly used preservatives (potassiumsorbate, sodium benzoate, sodium diacetate, sodium dehydroacetate, calcium propionate, and nisin) on the foraging behaviors of S. invicta foragers were evaluated under laboratory and field conditions. Four-choice tests (laboratory study) showed that the number of foraging ants on the preservative-treated (immersed in 2000-, 5000-, or 10,000-ppm solution for 30 min) and control (immersed in distilled water for 30 min) food was similar, with an exception of sodium dehydroacetate, which significantly decreased the number of foraging ants at the three tested concentrations. Interestingly, 46%, 58% and 71% of the food items treated with 2000-, 5000- and 10,000- ppm solutions of sodium dehydroacetate were buried with soil particles, respectively, whereas only 17% of the control food was similarly buried. Multiple-choice tests (field study) showed that food treated with the 5000- or 10,000-ppm solution of sodium dehydroacetate attracted significantly fewer S. invicta workers compared to other preservatives and the controls. Our study showed that the use of sodiumdehydroacetate should be avoided during the production of aqueous-based or liquid baits against S. invicta.