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      • '업','겁'派生形容詞에 對하여

        李智양 大田大學校 1988 論文集 Vol.7 No.1

        ‘업’ 또는 ‘겁’에 의한 파생형용사들은 오늘날 화석화된 것들이 많아 쉽게 파생어임을 깨닫기 어려우나, 대부분의 어근이 국어의 역사 속에서 확인될 수 있으므로 분석대상이 된다. 그 어근은 대체로 동사, 형용사, 명사 내지 의성의태어들이나 특이한 어근도 발견되는 등 광범위하다. 중세국어에서 이미 존재했던 ‘업’ 파생형용사들은 동사어간을 어근으로 한다는 통사적 제약과 어간 말음이 /i/나/j/로 끝나야 한다는 음운론적 제약을 가지는데, 이때의 /i/나/j/는 ‘업’과 통합되는 과정에서 truncation 되거나 glide 형성규칙의 적용을 받는다. 근대국어 이후에는 이러한 제약이 약화되어 명사, 의성의태어 등을 어근으로 하는 파생도 가능하고 동사의 경우도 어간 말음이 /i/나/j/로 국한되지 않아 다른 모음이나 자음으로 끝나는 동사에도 ‘업’이 연결될 수 있었다. 이렇듯 ‘업’이 취하는 어근의 영역이 확대되면서 ‘업’이 ‘브’나 ‘ㅂ’을 대치하는 새로운 파생어가 만들어지기도 하고, 어근 자체가 /i/말음을 가지지 않는 것으로 재구조화되기도 한다. 어근의 의미와 파생어의 의미 사이에는 다양한 종류의 변화가 엿보이나 기본적으로는 “주관적인 감정”이 그 주된 변화이며, 그 이외의 변화는 대체로 품사 전성에 따르는 불가피한 것이라고 생각된다. 이는 형용사에만 연결되는 형태라고 여겨졌던 ‘겁’에도 해당된다.

      • KCI등재

        갑상선기능저하증에 기인한 내인성 급사 1예 보고

        이정규,전지현,김민정,이규재,김한겸,조현득,채양석 大韓法醫學會 1999 대한법의학회지 Vol.23 No.2

        Although it is known that hypothyroidism can cause cardiac dysfunction, it is very hard to find a case report on sudden death due to hypothyroidism. There are only two reported cases on mediline; one is about a 15-year-old girl who died suddenly of Hashimoto's thyroiditis and the other is about a 31-year-old man who also died suddenly of hypothyroidism associated with chronic lymphocytic thyroiditis. Recently we found a young woman who unexpectedly died while she was sleeping. She was diagnosed as hypothyroidism when she went to hospital about a month before she died. At autopsy there were roughly four abnormal findings; Hashimoto's thyroiditis, mild chronic active hepatitis, diverticulosis and accessory spleen. Trace of chlorpheniramine was detected in gastric remains and blood alcohol level was 0.37 percent. To our knowledge, this is the first case reporting sudden and unexpected natural death associated with hypothyroidism in Korea.

      • KCI등재

        ASGO 7th International Workshop on Gynecologic Oncology

        Jie Yang,Yang Xiang,Beihua Kong 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.6

        The 7th International Workshop of the Asian Society of Gynecologic Oncology (ASGO) was held by the Chinese Society of Gynecologic Oncology (CSGO) and Peking Union Medical College Hospital on 27th to 28th August 2022. The 2022 workshop was the first ASGO congress that was held in mainland China. Due to the COVID situation, this workshop was conducted virtually. Five hundred eighty-seven participants from 13 countries/regions (Hong Kong, India, Indonesia, Italy, Japan, Korea, Mainland China, Malaysia, Singapore, Taiwan, Thailand, United Kingdom, and United State of America) attended the meeting (Table 1). Dr. Beihua Kong (Shandong, China), president of CSGO, served as the president. Dr. Yang Xiang, president-elect of Chinese Medical Association (CMA) Gynecologic Oncology division, served as the executive president of the 7th ASGO workshop. Following the 18th ASGO council meeting on August 26th (Fig. 1), the workshop was grandly held on August 27th and 28th virtually.

      • SCIESCOPUSKCI등재

        The Clinical Observation of Inflammation Theory for Depression: The Initiative of the Formosa Long COVID Multicenter Study (FOCuS)

        Shu-Tsen Liu(Shu-Tsen Liu),Sheng-Che Lin(Sheng-Che Lin),Jane Pei-Chen Chang(Jane Pei-Chen Chang),Kai-Jie Yang(Kai-Jie Yang),Che-Sheng Chu(Che-Sheng Chu),Chia-Chun Yang(Chia-Chun Yang),Chih-Sung Liang( 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.1

        There is growing evidence that the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with increased risks of psychiatric sequelae. Depression, anxiety, cognitive impairments, sleep disturbance, and fatigue during and after the acute phase of COVID-19 are prevalent, long-lasting, and exerting negative consequences on well-being and imposing a huge burden on healthcare systems and society. This current review presented timely updates of clinical research findings, particularly focusing on the pathogenetic mechanisms underlying the neuropsychiatric sequelae, and identified potential key targets for developing effective treatment strategies for long COVID. In addition, we introduced the Formosa Long COVID Multicenter Study (FOCuS), which aims to apply the inflammation theory to the pathogenesis and the psychosocial and nutrition treatments of post-COVID depression and anxiety.

      • KCI등재

        Chatbot Design Method Using Hybrid Word Vector Expression Model Based on Real Telemarketing Data

        ( Jie Zhang ),( Jianing Zhang ),( Shuhao Ma ),( Jie Yang ),( Guan Gui ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.4

        In the development of commercial promotion, chatbot is known as one of significant skill by application of natural language processing (NLP). Conventional design methods are using bag-of-words model (BOW) alone based on Google database and other online corpus. For one thing, in the bag-of-words model, the vectors are Irrelevant to one another. Even though this method is friendly to discrete features, it is not conducive to the machine to understand continuous statements due to the loss of the connection between words in the encoded word vector. For other thing, existing methods are used to test in state-of-the-art online corpus but it is hard to apply in real applications such as telemarketing data. In this paper, we propose an improved chatbot design way using hybrid bag-of-words model and skip-gram model based on the real telemarketing data. Specifically, we first collect the real data in the telemarketing field and perform data cleaning and data classification on the constructed corpus. Second, the word representation is adopted hybrid bag-of-words model and skip-gram model. The skip-gram model maps synonyms in the vicinity of vector space. The correlation between words is expressed, so the amount of information contained in the word vector is increased, making up for the shortcomings caused by using bag-of-words model alone. Third, we use the term frequency-inverse document frequency (TF-IDF) weighting method to improve the weight of key words, then output the final word expression. At last, the answer is produced using hybrid retrieval model and generate model. The retrieval model can accurately answer questions in the field. The generate model can supplement the question of answering the open domain, in which the answer to the final reply is completed by long-short term memory (LSTM) training and prediction. Experimental results show which the hybrid word vector expression model can improve the accuracy of the response and the whole system can communicate with humans.

      • SCOPUSKCI등재

        Effect of cell-penetrating peptide-conjugated estrogen-related receptor ${\beta}$ on the development of mouse embryos cultured in vitro

        Yang, Ning Jie,Seol, Dong-Won,Jo, Junghyun,Jang, Hyun Mee,Yoon, Sook-Young,Lee, Dong Ryul The Korean Society for Reproductive Medicine 2014 Clinical and Experimental Reproductive Medicine Vol.41 No.1

        Objective: Estrogen related receptor ${\beta}$ (Esrrb) is a member of the orphan nuclear receptors and may regulate the expression of pluripotencyrelated genes, such as Oct4 and Nanog. Therefore, in the present study, we have developed a method for delivering exogenous ESRRB recombinant protein into embryos by using cell-penetrating peptide (CPP) conjugation and have analyzed their effect on embryonic development. Methods: Mouse oocytes and embryos were obtained from superovulated mice. The expression of Oct4 mRNA and the cell number of inner cell mass (ICM) in the in vitro-derived and in vivo-derived blastocysts were first analyzed by real time-reverse transcription-polymerase chain reaction and differential staining. Then 8-cell embryos were cultured in KSOM media with or without $2{\mu}g/mL$ CPP-ESRRB protein for 24 to 48 hours, followed by checking their integration into embryos during in vitro culture by Western blot and immunocytochemistry. Results: Expression of Oct4 and the cell number of ICM were lower in the in vitro-derived blastocysts than in the in vivo-derived ones (p<0.05). In the blastocysts derived from the CPP-ESRRB-treated group, expression of Oct4 was greater than in the non-treated groups (p<0.05). Although no difference in embryonic development was observed between the treated and non-treated groups, the cell number of ICM was greater in the CPP-ESRRB-treated group. Conclusion: Treatment of CPP-ESRRB during cultivation could increase embryos' expression of Oct4 and the formation rate of the ICM in the blastocyst. Additionally, an exogenous delivery system of CPP-conjugated protein would be a useful tool for improving embryo culture systems.

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