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Practical method for determining load and resistance factors using third-moment transformation
Pei-Pei Li,Zhao-Hui Lu,Yan-Gang Zhao 국제구조공학회 2021 Structural Engineering and Mechanics, An Int'l Jou Vol.80 No.2
Load and resistance factor design (LRFD) is a suitable format for the reliability-based limit state design of structures. It has been adopted in many countries, such as the United States, Europe, Canada, and Japan. Usually, the first-order reliability method (FORM) is used to estimate the load and resistance factors, but it requires the determination of design points and complicated double iterative computations. Therefore, FORM is not easy or practical for engineers to use. This paper presents a simple, accurate method to determine the load and resistance factors utilizing the third-moment transformation, which does not require derivative-based iterations and can estimate the load and resistance factors without using the distribution of random variables. In addition, the proposed method provides enough accurate results within a wide range of target reliability indices. Therefore, this method should be effective and convenient for calculating the load and resistance factors in actual practice. Five numerical examples illustrate the proposed method’s efficiency and accuracy; FORM provides a benchmark for comparison.
Antibacterial and Antitumor Macrolides from Streptomyces sp. Is9131
Zhao Pei-Ji,Fan Li-Ming,Li Guo-Hong,Zhu Na,Shen Yue-Mao The Pharmaceutical Society of Korea 2005 Archives of Pharmacal Research Vol.28 No.11
Four compounds, including two novel macrolides, were isolated from an endophyte Streptomyces sp. Is9131 of Maytenus hookeri. Spectral data indicated that these compounds were dimeric dinactin (1), dimeric nonactin (2), cyclo-homononactic acid (3), and cyclo-nonactic acid (4). Bioassay results showed that dimeric dinactin had strong antineoplastic activity and antibacterial activity.
Antibacterial and Antitumor Macrolides from Streptomyces sp. Ls9131
Pei-Ji Zhao,Li-Ming Fan,Guo-Hong Li,Na Zhu,Yue-Mao Shen 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.11
Four compounds, including two novel macrolides, were isolated from an endophyte Streptomyces sp. ls9131 of Maytenus hookeri. Spectral data indicated that these compounds were dimeric dinactin (1), dimeric nonactin (2), cyclo-homononactic acid (3), and cyclo-nonactic acid (4). Bioassay results showed that dimeric dinactin had strong antineoplastic activity and antibacterial activity.
Zhao, Lian-Mei,Zheng, Zhao-Xu,Zhao, Xiwa,Shi, Juan,Bi, Jian-Jun,Pei, Wei,Feng, Qiang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14
For an exact comparison of mRNA transcription in different samples or tissues with real time quantitative reverse transcription-polymerase chain reaction (qRT-PCR), it is crucial to select a suitable internal reference gene. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and beta-actin (ACTB) have been frequently considered as house-keeping genes to normalize for changes in specific gene expression. However, it has been reported that these genes are unsuitable references in some cases, because their transcription is significantly variable under particular experimental conditions and among tissues. The present study was aimed to investigate which reference genes are most suitable for the study of gastric cancer tissues using qRT-PCR. 50 pairs of gastric cancer and corresponding peritumoral tissues were obtained from patients with gastric cancer. Absolute qRT-PCR was employed to detect the expression of GAPDH, ACTB, RPII and 18sRNA in the gastric cancer samples. Comparing gastric cancer with corresponding peritumoral tissues, GAPDH, ACTB and RPII were obviously upregulated 6.49, 5.0 and 3.68 fold, respectively. Yet 18sRNA had no obvious expression change in gastric cancer tissues and the corresponding peritumoral tissues. The expression of GAPDH, ${\beta}$-actin, RPII and 18sRNA showed no obvious changes in normal gastric epithelial cells compared with gastric cancer cell lines. The carcinoembryonic antigen (CEA), a widely used clinical tumor marker, was used as a validation gene. Only when 18sRNA was used as the normalizing gene was CEA obviously elevated in gastric cancer tissues compared with peritumoral tissues. Our data show that 18sRNA is stably expressed in gastric cancer samples and corresponding peritumoral tissues. These observations confirm that there is no universal reference gene and underline the importance of specific optimization of potential reference genes for any experimental condition.
Effects of inlet working condition and heat load on supercritical CO2 compressor performance
Pei Jinze,Zhao Yuanyang,Zhao Mingran,Liu Guangbin,Yang Qichao,Li Liansheng 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.8
The supercritical carbon dioxide (sCO2) Brayton power cycle is more effective than the conventional power cycle and is more widely applicable to heat sources. The inlet working conditions of the compressor have a higher influence on their operating performance because the thermophysical properties of the CO2 vary dramatically close to the critical point. The flow in the sCO2 compressor is simulated and the compressor performance is analyzed. The results show that the sCO2 centrifugal compressor operates outside of its intended parameters due to the change in inlet temperature. The sCO2 compressor requires more power as the inlet temperature increases. The compressor power is 582 kW when the inlet temperature is at 304 K. But the power is doubled when the inlet temperature increases to 314 K, and the change in the isentropic efficiency is within 5%. The increase in the inlet temperature significantly reduces the risk of condensation in centrifugal compressors. When the heat load of the sCO2 power system changes, the inlet pressure to the turbine can be kept constant by regulating the rotational speed of compressors. With the increase in rotational speed, the incidence loss and condensation risk increase
A Probationary Report on Therapy of Depression
Zhao Pei 강원대학교 인문과학연구소 2020 Journal of Humanities Therapy Vol.11 No.1
Depression is a typical emotional disorder of human being in today’s society, and the number of people suffering from depression is growing. Under the process of globalization, social production and technological progress have not brought real happiness to mankind. On the contrary, many people are increasingly feeling restless and exhausted. Today’s society is constantly instilling the concept of “nothing is impossible ”, people overwork and pursue performance, and constantly exploit themselves. Such exploitation is more terrible than the exploitation of outsiders because it appears at the same time as the feeling of freedom. However, when people’s efforts fail to achieve their goals, emotional disorders arise. In order to have a direct understanding of depression and its treatment methods, the author went to a psychiatric hospital for a month of internship. Through observing and recording cases, the author considers the possibility of philosophical intervention in the treatment of depression.
Adsorption performance of SO2 over ZnAl2O4 nanospheres
Ling Zhao,Sining Bi,Jiasi Pei,Xinyong Li,Ruihong Yu,Ji Zhao,Christopher J. Martyniuk 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.41 No.-
A type of uniform ZnAl2O4 nanospheres was selectively synthesized via a facile solvothermalmethod andtheir size was controlled to be 320–450 nm in diameter. It exhibits excellent SO2 adsorption capacity. Both physical structure and surface basicity were determined to play important roles in SO2 adsorptionprocess. In situ FTIR investigation revealed that adsorbed SO2 molecules formed surface bisulfite, sulfite,and bidentate binuclear sulfate. The CO2-TPD results revealed the SO2 adsorption capacity of thecatalysts correlated closely with their basicity sites. The mechanisms for SO2 adsorption andtransformation have been discussed in detail.
Zhang Pei-Pei,Liang Su-Xia,Wang Hua-Lun,Yang Kun,Nie Shao-Chen,Zhang Tong-Mei,Tian Yuan-Yuan,Xu Zhao-Yuan,Chen Wei,Yan Ying-Bin 한국통합생물학회 2021 Animal cells and systems Vol.25 No.5
The aim of this study was to compare the functional characteristics of mesenchymal stromal cells (MSCs) from a sheep model of traumatic temporomandibular joint (TMJ) fibrous and bony ankylosis. A sheep model of bilateral TMJ trauma-induced fibrous ankylosis on one side and bony ankylosis on the contralateral side was used. MSCs from fibrous ankylosed callus (FAMSCs) or bony ankylosed callus (BA-MSCs) at weeks 1, 2, 4, and 8 after surgery were isolated and cultured. MSCs derived from the bone marrow of the mandibular condyle (BM-MSCs) were used as controls. The MSCs from the different sources were characterized morphologically, phenotypically, and functionally. Adherence and trilineage differentiation potential were presented in the ovine MSCs. These cell populations highly positively expressed MSC-associated specific markers, namely CD29, CD44, and CD166, but lacked CD31 and CD45 expressions. The BA-MSCs had higher clonogenic and proliferative potentials than the FA-MSCs. The BA-MSCs also showed higher osteogenic and chondrogenic potentials, but lower adipogenic capacity than the FA-MSCs. In addition, the BA-MSCs demonstrated higher chondrogenic, but lower osteogenic capacity than the BM-MSCs. Our study suggests that inhibition of the osteogenic and chondrogenic differentiations of MSCs might be a promising strategy for preventing bony ankylosis in the future.