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Namkoong, Yeon,Yang, Hyung Jun,Song, Yun Heub American Scientific Publishers 2017 Journal of nanoscience and nanotechnology Vol.17 No.7
<P>We investigated the stress distribution and electrical characteristics according to changes in the process parameters in a vertical NAND (VNAND) flash cell with a poly-Si channel. We used technology computer-aided design to confirm that process parameters changes affect the stress distribution in a VNAND flash cell and the stress in the poly-Si channel. Also, we found that, as the stress distributions changed, the electrical characteristics depended significantly on the annealing temperature, channel hole angle, and tungsten intrinsic stress in a VNAND flash cell. Thus, the industry needs to develop and apply better process parameters and acquire a better understanding of how the electrical characteristics of a VNAND flash cell depend on those parameters.</P>
Regulation of Yolk Protein 2 Gene Expression in Drosophila immigrans
Yong, Namkoong,Chung, Yun Doo,Kim, Se Jae,Kwon, Hyeok Choon,Kim, Kyungjin,Lee, Chung Choo,Chung, Ki Wha,Choe, Oh Mok 濟州大學校 基礎科學硏究所 1995 基礎科學硏究 Vol.8 No.1
The three yolk protein genes (ypl, yp2 and yp3), encoding the three major polypeptide precursors of egg yolk, are developmentally regulated genes. The yps are expressed in sex-, stage-, and tissue-specific manners. It was reported that different cis-acting DNA regions are required for each of these tissue specificities in Drosophila melanogaster. In this paper, the developmental profile of yp2 expression was analyzed by northern blot and immunoblot analysis in Drosophila immigrans. The developmental profiles of mRAA and protein synthesis titers were very similar to those of D. melanogaster. The mRNA was first detected at more than 1 day after eclosion and the entire expression time of D. immigrans was longer than that of D.melanogaster. Electrophoretic mobility shift assay(EMSA) was carried out to identify the candidates for transacting factors that regulate the ovary-specific expression of yps. It revealed that only the crude extract from ovaries of adult females, not from fat bodies, could shift the mobility of the HindⅢ/PstI fragment of yp2. It suggests that this binding protein(s) may be an ovary-specific trans-acting factor(s). To purify the DNA binding protein, a glass bead binding purification method was devised. Using this method, we purified a putative DNA-binding protein with an apporximate molecular weight of 55-60 kDa.
동서연 ( Seo Yun Tong ),이용석 ( Yong Sek Lee ),박종섭 ( Jong Sup Park ),이준모 ( Jun Mo Lee ),남궁성은 ( Seung Eun Namkoong ) 대한산부인과학회 2006 Obstetrics & Gynecology Science Vol.49 No.9
목적: 부인과 영역에서 동시에 발생하는 원발암에 대한 임상적 분석을 통해 발생 빈도, 임상적 특징 및 예후를 알아보고자 한다. 연구 방법: 2000년 2월부터 2005년 1월까지 부인암을 진단 받은 환자 중 다발성 일차암으로 진단된 환자를 대상으로 임상병리적 특징, 치료 및 치료 후 결과에 대해 후향적으로 고찰하였다. 결과: 같은 기간에 부인암을 진단 받은 환자는 모두 3164명으로 그 중 20명이 동시성 일차암으로 진단되어 0.63%의 빈도를 나타내었다. 이중 생식기에 다발성 종양은 13명이었고 가장 많은 동시성 일차암은 자궁내막암과 난소암으로 20명 중 8명이었다 (40%). 자궁내막암과 난소암이 동시에 발생한 경우는 평균연령이 45.2세로 각각 종양이 발생한 경우보다 비교적 빠른 나이에 발생하였고, 조직학적으로는 자궁내막선암과 난소의 자궁내막양 선암이 동반된 경우가 5예로 빈도가 높았다. 수술 후 추적관찰기간 동안 2명의 환자가 사망하였고, 평균 생존 기간은 57개월 (SE 10.0, 95% Confidence interval 37-77)이었다. 결론: 부인암과 동시에 발생하는 원발암은 비교적 드문 질환이다. 그 중 자궁내막암과 난소암의 빈도가 가장 높고 일반적으로 단일암보다 젊은 나이에 발생하며, 수술과 보조적 치료로 비교적 좋은 예후를 기대할 수 있다. Objective: A histopathologic review of synchronous primary neoplasms of the female reproductive tract was presented and the possible correlation among discrete tumor subsets, natural history, and survival was evaluated. Methods: Between 2000 and 2005, 20 patients with synchronous primary cancers of the gynecologic malignancy were identified. Clinical and pathologic informations were obtained from medical records. Kaplan-Meier survival analysis was performed. Results: The patients with Synchronous primary malignancies constituted 0.63% of all genital malignancies. The most frequently observed synchronous neoplasms were those of the ovary with the endometrium (40%). The mean age of patient with synchronous ovarian and endometrial cancer was 45.2 years. 8 patients underwent the hysterectomy with bilateral salpingo-oophorectomy and adjuvant therapy. The mean survival is 57 months (SE 10.0, 95% Confidence interval 37-77). Conclusion: Synchronous ovarian and endometrial cancers were detected in relatively early age and the prognosis was favorable.
강석구,정경윤,박찬희,남궁은영,김태현 성균관대학교 기초과학연구소 1995 論文集 Vol.46 No.2
The coupling reaction of iodobenzene with allylic diols in the presence of Pd(OAc)_2 and nBu_3P as catalysts using K_2CO_3 as base afforded the phenyl-substituted allylic diols. However, under the same reaction conditions with Et3N as base, phenyl-substituted α-hydroxy ketone was obtained.