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      • Dynamic Hand Gesture Segmentation Method Based on Improved Kalman Filter and Weighted Skin-Color Model

        Zhang Qiu-yu,Lu Jun-chi,Wei Hui-yi,Zhang Mo-yi,Duan Hong-xiang 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.6

        In order to improve the problems of segmentation accuracy and real-time existing in dynamic hand gesture under complex backgrounds, this paper presents a kind of dynamic hand gesture segmentation method based on improved Kalman filter and weighted skin-color model. Firstly, improved Kalman filter is utilized to process hand gesture image of hand gesture video sequences and get rough hand gesture results. Secondly, weighted skin-color model is applied to process rough results of hand gesture segmentation and segment hand gesture. Finally, morphological method is utilized to deal with gesture segmentation result, getting rid of the holes in the hand gesture’s binary image to realize the segmentation of dynamic hand gesture. Experiments show that the proposed method can segment hand gesture from dynamic hand gesture video sequences with complex backgrounds effectively. And the accuracy of hand gesture segmentation is high.

      • KCI등재

        A transcription factor TaTCP20 regulates the expression of Ppd-D1b in common wheat

        Wei Fan,Song Tianqi,Zhou Jianfei,Cheng Jie,Li Ruibo,Yu Ming,Zhang Yunrui,Yu-Yang Song,Zhang Bo,Zhang Xiaoke 한국식물생명공학회 2021 Plant biotechnology reports Vol.15 No.3

        Photoperiod (Ppd) genes play an important role in the adaptation of wheat to the ecological environment. However, the transcriptional regulation mechanism of photoperiodic genes has remained elusive. This study isolated a full-length promoter of Ppd-D1b (2518 bp) from the common wheat genome. Several essential core cis-acting elements and numerous light-responsive cis-acting regulatory elements were identifed in Ppd-D1b promoter by the in-silico analysis. Ten 5’-deleted length fragments of the Ppd-D1b promoter fused with GUS were constructed and named D0 ~D9, then transferred them into Arabidopsis thaliana. GUS gene driven by full-length (D0) in transgenic Arabidopsis thaliana showed the same rhythm with Ppd-D1b in wheat under short-day conditions (SDs, 8-h light/16-h dark). The expression of GUS gene in D0 reached its peak at 3 h after dawn, then decreased to the lowest and remained stable. Analysis of the series of 5’-deleted fragments showed that at 3 h after dawn, GUS gene expression activity decreased signifcantly in D7a due to removal of CHEBS (CCA1 HIKING EXPEDITION binding site). Moreover, yeast one-hybrid (Y1H) and dual-luciferase (dual-LUC) assays revealed that TaTCP20 could bind to the Ppd-D1b promoter to increase its transcriptional activity. This study revealed a transcription factor, TaTCP20, which activated Ppd-D1b by binding to CHEBS, provided a foundation for the theoretical research on wheat’s photoperiodic response mechanism.

      • Risk of Treatment-related Mortality with Sorafenib in Patients with Cancer

        Zhang, Xin-Ji,Zhang, Tian-Yi,Yu, Fei-Fei,Wei, Xin,Li, Ye-Sheng,Xu, Feng,Wei, Li-Xin,He, Jia Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

        Background: Fatal adverse events (FAEs) have been reported with sorafenib, a vascular endothelial growth factor receptor kinase inhibitor (VEGFR TKI). We here performed an up-to-date and detailed meta-analysis to determine the overall risk of FAEs associated with sorafenib. Methods: Databases, including PubMed, Embase and Web of Science, and abstracts presented at the American Society of Clinical Oncology annual meetings were searched to identify relevant studies. Eligible studies included randomized controlled trials evaluating sorafenib effects in patients with all malignancies. Summary incidence rates, relative risks (RRs), and 95% confidence intervals (CIs) were calculated for FAEs. In addition, subgroup analyses were performed according to tumor type and therapy regimen. Results: 13 trials recruiting 5,546 patients were included in our analysis. The overall incidence of FAEs with sorafenib was 1.99% (95%CI, 0.98-4.02%). Patients treated with sorafenib had a significantly increased risk of FAEs compared with patients treated with control medication, with an RR of 1.77 (95%CI 1.25-2.52, P=0.001). Risk varied with tumour type, but appeared independent of therapy regimen. A significantly increased risk of FAEs was observed in patients with lung cancer (RR 2.26; 95% CI 1.03-4.99; P= 0.043) and renal cancer (RR 1.84; 95% CI 1.15-2.94; P= 0.011). The most common causes of FAEs were hemorrhage (8.6%) and thrombus or embolism (4.9%). Conclusions: It is important for health care practitioners to be aware of the risks of FAEs associated with sorafenib, especially in patients with renal and lung cancer.

      • KCI등재

        Accurate Parameter Design for Radial AC Hybrid Magnetic Bearing

        Wei-Yu Zhang,Huang-Qiu Zhu 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.

        For more stable operation of radial AC hybrid magnetic bearing (radial AC HMB), it is particularly important to realize optimizationdesign of parameters for its prototype. The paper focuses on solving the several typical defects of traditional methods and puts forwardspecific countermeasures on improving its disadvantages. Thus, a new parameter design method based on two sets of magnetic fieldsystem (the stator core magnetic field system and the air gap field system) is proposed to calculate the structure and electromagnetismparameters of the radial AC HMB. Using the proposed parameter design method, a finite element model of radial AC HMB basedon the design results are simulated in finite element analysis software. The simulation results are consistent with the expectedparameters calculation results very well, which show accuracy of the parameters and the proposed method. To illustrate the validityof the parameter design approaches further, the verification experiment is conducted. The operating experimental results show thatthe radial AC HMB has high stability, fast start of suspension and fine anti-disturbance. Moreover, system performance comparisonresults show the control system based on the new parameter design method has stronger anti-disturbance characteristics than thatbased on the traditional parameter design method.

      • Association of Six Susceptibility Loci with Prostate Cancer in Northern Chinese Men

        Zhang, Yu-Rong,Xu, Yong,Yang, Kuo,Liu, Ming,Wei, Dong,Zhang, Yao-Guang,Shi, Xiao-Hong,Wang, Jian-Ye,Yang, Fan,Wang, Xin,Liang, Si-Ying,Zhao, Cheng-Xiao,Wang, Fei,Chen, Xin,Sun, Liang,Zhu, Xiao-Quan,Zh Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

        Background/Aim: Six prostate cancer (PCa) susceptibility loci were identified in a genome-wide association study (GWAS) in populations of European decent. However, the associations of these 6 single-nucleotide polymorphisms (SNPs) with PCa has remained tobe clarified in men in Northern China. This study aimed to explore the loci associated with PCa risk in a Northern Chinese population. Methods: Blood samples and clinical information of 289 PCa patients and 288 controls from Beijing and Tianjin were collected. All risk SNPs were genotyped using polymerase chain reaction (PCR)-high resolution melting curve technology and gene sequencing. Associations between PCa and clinical covariates (age at diagnosis, prostate-specific antigen [PSA], Gleason score, tumor stage, and level of aggressiveness) and frequencies of alleles and genotypes of these SNPs were analyzed using genetic statistics. Results: Among the candidate SNPs, 11p15 (rs7127900, A) was associated with PCa risk (P = 0.02, odds ratio [OR] = 1.64, 95% confidence interval [CI] = 1.09-2.46). Genotypes showed differences between cases and controls on 11p15 (rs7127900, A), 11q13 (rs7931342, T), and HNF1B (rs4430796, A) (P = 0.03, P = 0.01, and P = 0.04, respectively). The genotype TG on 11q13 (rs7931342, T) was positively associated with an increased Gleason score (P = 0.04, OR = 2.15, 95% CI = 1.02-4.55). Patients carrying TG on 17q24 (rs1859962, G) were negatively associated with an increased body mass index (BMI) (P = 0.03, OR = 0.44, 95% CI = 0.21-0.92) while those with AG on HNF1B (rs4430796, A) were more likely to have PSA increase (P = 0.002). Conclusion: Our study suggests that 11p15 (rs7127900, A) could be a susceptibility locus associated with PCa in Northern Chinese. Genotype TG on 11q13 (rs7931342, T) could be related to an increased Gleason score, AG on HNF1B (rs4430796, A) could be associated with PSA increase, and TG on 17q24 (rs1859962, G) could be negatively associated with an increased BMI in Chinese men with PCa.

      • KCI등재

        Mathematical formulation and an improved moth–flame optimization algorithm for parallel two-sided disassembly line balancing based on fixed common stations

        Zhang Yu,Zhang Zeqiang,Yin Tao,Liang-Wei Jiang 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.1

        Nowadays, rapid product iterations result in large quantities of end-of-life products. To meet the fast-growing demand for remanufacturing engineering, companies have quickened the standardization and industrialization of waste dissembling. Two-sided disassembly lines can effectively disassemble large-sized products on both sides of the lines, and parallel disassembly lines can disassemble multiple products simultaneously with fewer workstations and higher production efficiency. Combining the two types of disassembly can effectively increase the disassembly efficiency of large-sized products. However, the parallel two-sided disassembly line has not been fully investigated because of the essential complexity of the problem. Therefore, this research introduced the parallel two-sided disassembly line balancing problem with fixed common stations. First, a multi-objective mixed-integer programming model is established to solve the problem for the first time. The model is proved to be correct through small-scale numerical examples. Second, a multi-objective improved moth–flame optimization algorithm is implemented to solve the proposed large-scale problems. The proposed algorithm employs a two-phase decoding approach to design the scheme and a discrete moth for fire operation to search and replace new individuals, and then a restart strategy is introduced to reduce the probability of the population falling into a local optimum. Finally, the algorithm solved extensive disassembly line balancing problems with different layouts, including the straight-line, two-sided, and parallel two-sided, and case studies demonstrated the reliability and validity of the proposed method.

      • KCI등재

        Analysis of the Relationship between Breaking Stress and Whiteness in a New Hair Bleaching Method

        Wei Wang,Qing-hui Mao,Yu Zhang,Jian-gang Qu,Zhi-jie Liang,Jia Yu,Lin-juan Zheng,Li Zhang 한국섬유공학회 2020 Fibers and polymers Vol.21 No.12

        In order to investigate the relationship between breaking stress and whiteness in a bleaching treatment withlaccase, hair samples from three biogeographically distinct populations were characterized by various chemical and physicaltechniques. Factors affecting whiteness and breaking stress were investigated by attenuated total reflection infraredspectroscopy, atomic absorption spectroscopy, X-ray diffraction and scanning electron microscopy. The results reveal thatwhiteness and breaking stress after bleaching are primarily influenced by the diversity of concentration of metal ions andfunctional groups in the hair. The hair samples with lower content of metal ions obtain better whiteness and higher stressretention. The presence of OH functional group increases the final whiteness of the hair sample, while lack of that not onlydecreases the whiteness but also leads to more stress loss. In addition, the presence of the C=C functional group alsodecreases the whiteness.

      • KCI등재

        Protective effect of hepatocyte-enriched lncRNA-Mir122hg by promoting hepatocyte proliferation in acute liver injury

        Yu Zhenjun,Li Yuhan,Shao Shuai,Guo Beichen,Zhang Mengxia,Zheng Lina,Zhang Kun,Zhou Feng,Zhang Li,Chen Chiyi,Jiang Wentao,Hong Wei,Han Tao 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

        Some long noncoding RNAs (lncRNAs), which harbor microRNAs in their gene sequence and are also known as microRNA host gene derived lncRNAs (lnc-MIRHGs), play a dominant role alongside miRNAs, or both perform biological functions synergistically or independently. However, only a small number of lnc-MIRHGs have been identified. Here, multiple liver injury datasets were analyzed to screen and identify the target lncRNA Mir122hg. Mir122hg was mainly enriched in liver tissues with human-mouse homology. In both CCl4-induced acute liver injury and Dgal/LPS-induced fulminant liver failure in mice, Mir122hg was sharply downregulated at the early stage, while a subsequent significant increase was only found in the CCl4 group with liver recovery. Overexpression and silencing assays confirmed that Mir122hg played a protective role in acute injury by promoting hepatocyte proliferation in vivo and in vitro. Consistent with the results of gene enrichment analysis, Mir122hg binding to C/EBPα affected its transcriptional repression, promoted gene transcription of downstream chemokines, Cxcl2, Cxcl3, and Cxcl5, and exerted pro-proliferative effects on hepatocytes through activation of the AKT/GSK-3β/p27 signaling pathway by CXC/CXCR2 complexes. This study identifies a novel lncRNA with protective effects in acute liver injury and demonstrates that the binding of Mir122hg-C/EBPα promotes hepatocyte proliferation via upregulation of CXC chemokine and activation of AKT signaling.

      • SCIESCOPUSKCI등재

        Pathological Impact on the Phyllosphere Microbiota of Artemisia argyi by Haze

        ( Yu-zhu Zhang ),( De-yu Jiang ),( Chi Zhang ),( Kun Yang ),( Huai-fu Wang ),( Xiu-wen Xia ),( Wei-jun Ding ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 Journal of microbiology and biotechnology Vol.31 No.4

        The pathological impact of haze upon the phyllosphere microbiota awaits investigation. A moderate degree of haze environment and a clean control were selected in Chengdu, China. Artemisia argyi, a ubiquitously distributed and extensively applied Chinese herb, was also chosen for experiment. Total genome DNA was extracted from leaf samples, and for metagenome sequencing, an Illumina HiSeq 2500 platform was applied. The results showed that the gene numbers of phyllosphere microbiota derived from haze leaves were lower than those of the clean control. The phyllosphere microbiota derived from both haze and clean groups shared the same top ten phyla; the abundances of Proteobacteria, Actinomycetes and Anorthococcuso of the haze group were substantially increased, while Ascomycetes and Basidiomycetes decreased. At the genus level, the abundances of Nocardia, Paracoccus, Marmoricola and Knoelia from haze leaves were markedly increased, while the yeasts were statistically decreased. KEGG retrieval demonstrated that the functional genes were most annotated to metabolism. An interesting find of this work is that the phyllosphere microbiota responsible for the synthesis of primary and secondary metabolites in A. argyi were significantly increased under a haze environment. Relatively enriched genes annotated by eggNOG belong to replication, recombination and repair, and genes classified into the glycoside hydrolase and glycosyltransferase enzymes were significantly increased. In summary, we found that both structure and function of phyllosphere microbiota are globally impacted by haze, while primary and secondary metabolites responsible for haze tolerance were considerably increased. These results suggest an adaptive strategy of plants for tolerating and confronting haze damage.

      • KCI등재

        Investigation into performance enhancements of Li–S batteries via oxygen-containing functional groups on activated multi-walled carbon nanotubes using Fourier transform infrared spectroscopy

        Yu Hai Wang,Zhe Dai,Chao Yue Zhang,Guo Wen Sun,Zhong Wei Lu,Xiu Ping Gao,Geng Zhi Sun,Wei Lan,Zhen Xing Zhang,Xiao Jun Pan,Jin Yuan Zhou 한국물리학회 2020 Current Applied Physics Vol.20 No.9

        It was demonstrated that the electrochemical performance enhancements in KOH-activated carbon materials should be mainly due to the created polar oxygen-containing functional groups (OFGs, such as such as C–O, C–– O, –OH, and O–C–– O), while the role of each OFGs on the electrochemical enhancements is still unclear. In this work, KOH activation treatments were systematically conducted on carbon nanotubes (CNTs) to explore the role of each OFG on the performance enhancements of Li–S batteries (LSBs). Results showed that the capacity of activated-CNT-sulfur (a-CNT-S) cathodes is 33% higher than that of the pristine CNT-S cathodes, and their rate capability and cycling stability are also enhanced. And the electrochemical analysis combining with Fourier transform infrared spectroscopy indicated that the formed C–O bonds are the real factor for the enhanced electrochemical performances of a-CNT-S cathodes. Furthermore, the optimal activation conditions on CNTbased cathodes for LSBs were optimized to be 10 min at 700 ℃.

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