일반논문 : 고금도(古今島) 관왕묘(關王廟) 연구

유성웅 ( Sung Woung Yu ),장경희 ( Kyung Hee Jang ) 한서대학교 동양고전연구소 2015 동방학 Vol.32 No.-

고금도(古今島) 관왕묘(關王廟)는 정유재란을 기억하는 역사적 상징이다. 본고는 1598년 창건된 이후 한·중·일 삼국의 역사적 관계에 따라 끊임없이 변화되어 오늘에 이른 고금도 관왕묘를 연구 대상으로 하여 다음과 같은 역사적 사실을 밝혀냈다 첫째, 고금도 관왕묘는 정유재란 당시 조선에 파병된 진린(陳璘) 도독과 명나라 수군(水軍)에 의해 1598년 창건되어, 군신(軍神)인 관우(關羽)와 해신(海神)인 마조(마祖) 등을 함께 배향하였다. 둘째, 고금도 관왕묘는 조선 후기에 묘사(廟祠) 건물의 구조와 향사 대상이 변화된 것이 특징이다. 1598년 정전(正殿)에 관왕과 마조를 모시고 명 수군들의 제향을 받았다. 1666년 정전과 동·서무(東西楙)를 갖춘 品자형 구조였다. 정전에는 관우를 모셨으며 동무에는 진린 도독과 이순신 장군을 함께 배치하여 조선 수군들의 제향을 받았다. 1791년 고금도 관왕묘에 ``탄보묘(誕報廟)``라는 사액(賜額)을 내려 묘격(廟格)이 승격되었고, 노량대첩 당시 전사한 명 등자룡(鄧子龍) 장군이 합사되었다. 이에 따라 동무에는 진린 도독과 등자룡 장군이, 서무에는 이순신 장군이 배치되었다. 하지만 일제 강점기인 1940년 고금도 관왕묘는 훼철되었고, 해방 이후에는 이충무공 유적으로 바뀌었다. 따라서 16세기 한·중 문화 교류를 실질적으로 증명하는 문화유산인 고금도 관왕묘가 향후 원형대로 복원되길 기대한다. Founded In 1598, when the Japanese invaded Korea for the 2nd time, Gogeumdo Gwanwangmyo is a historical symbol to remember the Japanese invasion of Korea. Since the foundation, Gogeumdo Gwanwangmyo has gone through continuous transformations as responses to changing relationships among Korea, China and Japan. The paper aims to bring to light important historical facts and argue for the necessity to restore Gogeumdo Gwanwangmyo to its original form. First, Gogeumdo Gwanwangmyo was founded in 1598, by the Admiral Chen Lin (陳璘) from the Ming Dynasty. The shrine housed the war god (軍神), King Guan Yu (關羽) and the god of the sea (海神), Majo (?祖). In their hometown, Guangdung (廣東) in China, these military leaders followed the tradition of dedicating memorial service to both King Guan Yu and Majo. In founding Gogeumdo Gwanwangmyo, they applied the same concept. Particularly in 1583, Chen Lin had previously erected a Matang Gwanjemyo (馬塘關帝廟) in Guangdong. This experience offered him the motivation to build Gwanwangmyo in Korea. Secondly, the late Joseon dynasty witnessed shifts in commemorative service tradition, which centered on the architectural structure of shrine, and the target of commemorative service. In 1598, the main shrine housed the King Guan Yu and the Majo. In 1666, the entire structure of shrines changed to have the 品 shape, having the East shrine and the West shrine under the main shrine. The main shrine was dedicated to King Guan Yu. The East shrine was dedicated to the Admiral Chen Lin and the Admiral Lee Sun-shin. In addition to the East and the West rituals buildinges, the year 1713 saw an addition of a small temple(玉泉寺) whose role is today``s equivalent of the guard office. The same year saw the elevation of national status of the commemorative service for King Guan Yu (關羽), the Admiral Chen and the admiral Lee. In 1791, the King Jongjo granted Gogeumdo Gwanwangmyo a signature board that reads ``Tanbomyo (誕報廟)``, which also contributed to raising the shrine``s status. That year also saw the expansion of the scope of the memorial service to dedicate to one more soul, the general Deng Zi Long (鄧子龍), who died during the Battle of Noryang. Accordingly, the structure is re-arranged to have the East shrine dedicated to the admiral Chen and the general Deng, and the West shrine to the admiral Lee. In the post Battle of Noryang era, Gogeumdo Gwanwangmyo became an internationally renowned shrine housing souls of national heroes of the Joseon and the Ming dynasties. But, under the Japanese colonial rule, Gogeumdo Gwanwangmyo was destroyed. After liberation, in light of the shrine``s value as a relic of the admiral Lee, the Korean government designated Gogeumdo Gwanwangmyo as Historic Site No. 114. Currently, the main shrine is used to hold a national memorial service for the Admiral Lee, with the general Lee Young-nam. In particular, this latter represents important historical heritage to prove the cultural exchange that existed between China and Korea.

녹동균 세포외막 단백질 백신 CFC-1-101의 안정성 및 면역원성 검토 : 임상 제 Ⅰ/Ⅱa상 시험

장인진,김익상,유경상,임동석,김형기,신상구,장우현,박완제,이나경,정상보,안동호,조양제,안보영,이윤하,김영지,남성우,김현수 대한감염학회 1998 감염 Vol.30 No.3

목적 : 제일제당에서는 녹농균의 세포외막 단밸질을 유효성분으로 하는 백신인 CFC-101을 개발하였으며, 동물시험에서 이 백신의 안전성과 유효성을 입증하였다. 본 연구에서는 이 녹농균 백신의 인체에 대한 안전성과 면역원성을 평가하는 동시에 인체 접종시의 최적 투여 용량을 결정하기 위하여 제 I/Ⅱa상 임상시험을 수행하였다. 방법 : 건강한 성인 남자를 피험자로 선별하여 각 용량군에 백신투여자 6명, 위약투여자 2명을 배정하였다. 백신 투여군은 0.25mg, 0.5mg 또는 1.0mg 용량의 녹농균 백신을 7일 간격으로 3회에 걸쳐 근육주사 하였으며, 위약 투여군에게는 세포외막 단백질을 제외한 동일한 성분을 투여하였다. 백신접종 후 국소적 또는 전신적인 반응의 발생여부를 관찰하고, 혈액시료를 체취하여 백신의 역가와 유효성을 검정하였다. 결과 : 녹농균 백신 CFC-101은 모든 접종자에서 양호한 내약성을 보였다. 또한 0.5mg 과 1.0mg 백신 투여군에서는 100%의 항체양전율을 나타내었다. 생성된 항체는 녹농균 세포외막단백질에 특이성을 보였고, 녹농균 감염에 대해 방어효능이 있었다. 결론 : 이와같은 결과로부터 이 녹농균 백신은 인체에 안전하게 투여할 수 있으며, 높은 항체 생성능으로 감염방어 효능을 보이고 0.5mg과 1.0mg이 최적용량인 것으로 판단되었다. Background : We developed a Pseudomonas aeruginosa outer membrane protein(OMP) vaccine CFC-101, and the prophylactic efficacy of which has been demonstrated in animal models. In order to evaluate the safety and immunogenicity of the P. aeruginosa vaccine, we carried out a phase I/Ⅱa clinical trial in healthy male volunteers. Methods : Groups of eight volunteers, including two placebo subjects, were vaccinated intramuscularly with three doses of 0.25, 0.5 or 1.0 mg of the vaccine at one week intervals. Sings of systemic and local reactions observed after vaccination were recorded for each vaccinee for 5 days. Physical examinations were performed on days 0, 1, 7, 8, 14, 15, 21, and 42, and clinical laboratory tests were done on days 0, 3, and 21. Blood samples for assay of serum antibody levels were obtained up to 42 days after the first vaccination. Results : The vaccine was generally well tolerated by all vaccinees, showing no significant side effects. In the three dosage groups, all vaccinees, except one receiving the 0.25 mg dose, showed significant elevation in serum IgG antibody titers against the vaccine proteins, indicating 100% seroconversion in 0.5 and 1.0 mg groups. The human antibodies induced by the vaccine were specific for P. aeruginosa OMPs, as confirmed by western blot analysis and immunoprecipitation assays. The capacity of the human antisera to enhance opsonophagocytic killing activity by polymorphonuclear leukocytes and to confer protection against P. aeruginosa infections indicates that the antibodies elicited by the vaccine have protective efficacy. Conclusion : We conclude that the P. aeruginosa OMP vaccine is safe and effective for human use and its optimal dose to be 0.5 or 1.0 mg.

역행성 심정지 도관 삽입을 위한 술 중 경식도심초음파의 유용성

유미숙;최원주;김정원;박장수;김경태;김지연;어상일 인제대학교 2011 仁濟醫學 Vol.32 No.-

Background: Retrograde cardioplegia catheter (RCC) insertion is one of methods for administration of cardioplegics during cardiopulmonary bypass (CPB). However its success rate depends on only surgeon's experience. We thought the transesophageal echocardiography (TEE) can guide the R CC insertion, because TEE is commonly used for monitoring status of heart during cardiac surgery. This study was designed to evaluate the RC C insertion time by TEE guidance versus conventional method without T EE guidance. Methods: Sixty patients who were scheduled to undergo elective coronary artery bypass graft (CABG) surgery under general anesthesia were divided into groups as follows: group T [RCC insertion into coronary sinus (CS) by TEE guidance, n=30] and group C [RCC insertion into CS by conventional method, n=30]. We recorded the time of insertion of RCC in to CS in two groups. RCC insertion was done by TEE guidance in case that time was over two minutes by conventional methods in group C. Results: The overall time of RCC insertion into CS was 63.8 ± 23.6 seconds in the Group T and 102.3 ±55.7 seconds in the Group C, respectively (p=0.001). There were no complications during RCC into CS by T EE guidance. Conclusions: TEE guidance for RCC insertion into CS is shorten the time of insertion.

한국인 환자에서 Vancomycin의 집단약동학 (Population Pharmacokinetics)에 관한 연구

유경상,배균섭,이주연,조주연,장인진,신상구,신완균 大韓臨床藥理學會 1998 臨床藥理學會誌 Vol.6 No.2

서방형 Diltiazem제제의 개발을 위한 약동학/약력학적 특성 검토

유경상,배균섭,조주연,장인진,신상구 大韓臨床藥理學會 1998 臨床藥理學會誌 Vol.6 No.2

아메바성 대장염과 연관된 Henoch-Scho¨nlein Purpura 1예

장재현,원경준,이준,변유미,이재광,김영훈,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Henoch-SchonIein purpura is a common form of vasculitis primarily involving the skin, the gastrointestinal tract, the joints, the kidneys, and the nervous system. The etiological investigations are essential, because triggering factors are found in approximately half the patients such as viral, bacterial and parasitic infections, drugs, toxins, systemic diseases and cancer. But it's the correlation between Henoch-SchonIein purpura and Entamoeba histolytica has been rarely reported. We report a 29-years-old woman with Henoch-SchoIein purpura complicated by the lower gastrointestinal bleeding caused by the amoebic colitis. She complained of cramping abdominal pain, lower extremity purpura and hematochezia. Cysts and trophozoites of Entamoeba histolytica were detected in her stool. Skin biopsy demonstrated the leukocytoclastic vasculitis. She was administered metronidazole 1,500㎎ a day for the treatment of amebic colitis. Her hematochezia was improved, but the abdominal pain and purpura were not. The subsequent corticosteroid therapy improved her symptoms.

M2M-MIB를 이용한 분산구조 CNM

이유경,김장형,송왕철 濟州大學校 工科大學 産業技術硏究所 1997 尖端技術硏究所論文集 Vol.8 No.2

Recently, Virtual Private Network(VPN) services are widely used to establish enterprise networks. The enterprise networks may be distributed locally and have been used to be in the form of leased lines of the public networks. However. VPN provides more efficient ways of establishing enterprise networks than ever. VPN services are provided depending upon contracts between the VPN provider and the customer, and the tariff can be asked only on the basis of usage. In addition. to meet various demands of customer, the VPN provider supplies the management information and supports the limited managing rights for the related public network resources. The coustomers be able to manage their own VPNs. Nowadays, trends toward implementing asynchronous transfer mode (ATM) technologies for public and/or private networks have been increasing and CNM has been also considered in the ATM network environment. ATM Forum provides M3 Specifications for the CNM, but VPN services across the several public networks are not considered. Therefore, in this paper, a distributed architecture of CNM using M2M-MIB is proposed and implemented using the UT-SNMP, package of University of Twente.

中學 科學敎育의 探究學習에 대한 評價問項 開發 (Ⅱ)

閔庚德,楊洪準,李善行,鄭遠佑,이병교,金裕漢,羅長薰 경북대학교 과학교육연구소 1985 科學敎育硏究誌 Vol.9 No.-

This study was accomplished to develope the evaluation items for inquiry learning in the 2nd grade Middle School Science for the consecutive study of the evaluation items for inquiry learning in the 1st grade Middle School Science(U-Hang Ki et al, 1984). In this study, paper and pencil test items and performance test items are made by analyzing the abilities of inquiry according to the contents and four basic experiments from each unit in the 2nd grade Middle school science. These evaluation items were applied to tke five classes of the 2nd grade of middle school to test their validity. It is desirable that performance test schuld be used for the evaluation for the abilities of inquiry which can not be evaluated by paper and pencil test. In the evaluation methods of performance test, tester evaluation, peer evaluation and self-evaluation can be applied to the science class in a multi-student class. In higher grade, however tester evaluation is more desirable than peer and self evaluation. It is found that peer evaluation and self-evaluation make possible the perfect study by feedback.

뇌성마비아의 모발내 중금속 함량 분석

안경희,김희상,유창현,윤동환,홍장혁,유승돈,이준원 경희대학교 2001 慶熙醫學 Vol.17 No.1

M2M-MIB를 이용한 분산구조 CNM

이유경,김장형,송왕철 濟州大學校 産業技術硏究所 1997 산업기술연구소논문집 Vol.8 No.2

Recently, Virtual Private Network(VPN) services are Lvidely used to establish enterprise networks. The enterprise networks may be distributed locally and have been used to be in the form of leased lines of the public networks. However. VPN provides more efficient ways of establishing enterprise networks than ever. VPN services are provided depending upon contracts betlveen the VPN provider and the customer. and the tariff can be asked only on the basis of usage. In addition, to meet various demands of customer. the VPN provider supplies the management information and supports the limited managing rights for the related public network resources. The customers be able to manage their own VPNs. Nowadays. trends toward implementing asynchronous transfer mode (ATM) technologies for public and/or private netLvorks have been increasing and CNM has been also considered in the ATN network environment, ATM Forum provides M3 Specifications for the CNM. but VPN services across the seireral public networks are not considered. Therefore. in this paper, a distributed architecture of CNM using M2M-MIB is proposed and implemented using the UT-SNMP. package of University lof Twente.