http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Koo, YoungWon,Choi, Eun-Ji,Lee, JaeYoon,Kim, Han-Jun,Kim, GeunHyung,Do, Sun Hee Elsevier 2018 Journal of industrial and engineering chemistry Vol.66 No.-
<P><B>Abstract</B></P> <P>Current surgical treatments for osteochondral injuries include chondrocyte transplantation, osteochondral grafts, and bone marrow stimulation. Despite these approaches, repaired tissues often show limited regeneration resulting in fibrocartilage formation with poor mechanical properties. To overcome these shortcomings, a regenerative cell-laden scaffold therapy is a promising treatment option. In this study, we propose a three-dimensional (3D) micro-sized mesh structure using a cell-laden collagen bioink. To achieve the optimal cell-printing condition for the fabrication of cell-laden collagen structure, porous mesh collagen scaffold (PMCS) were assessed for the mechanical properties, printability and cell viability analysis. <I>In vivo</I> regenerative effects of PMCS were compared to the injecting hydrogel without pores (non-porous collagen scaffold (NPCS)), collagen/poly(ε-caprolactone) (PCL) hybrid scaffold (CPHS)), and pure PCL scaffold (PPS). The porous mesh-structured/cell-laden collagen scaffold (PMCS) showed significantly enhanced cartilage regeneration <I>in vivo</I> compared to other conditions.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Lee, Soon Bo,Ju, Youngwon,Kim, Yeoju,Koo, Chong Min,Kim, Joohoon The Royal Society of Chemistry 2013 Chemical communications Vol.49 No.79
<P>We report the electrochemical grafting of amine-terminated dendrimers encapsulating nanoparticles onto indium tin oxide (ITO) surfaces.</P> <P>Graphic Abstract</P><P>Electrografting of dendrimer-encapsulated nanoparticles allows spatially controlled surface functionalization of ITO with various catalytic nanoparticles and biologically active materials. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3cc41403e'> </P>
Lee, JiUn,Yeo, Miji,Kim, WonJin,Koo, YoungWon,Kim, Geun Hyung Elsevier 2018 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES Vol.110 No.-
<P><B>Abstract</B></P> <P>Cell-printing is an emerging technique that enables to build a customized structure using biomaterials and living cells for various biomedical applications. In many biomaterials, alginate has been widely used for rapid gelation, low cost, and relatively high processability. However, biocompatibilities enhancing cell adhesion and proliferation were limited, so that, to overcome this problem, an outstanding alternative, collagen, has been extensively investigated. Many factors remain to be proven for cell-printing applications, such as printability, physical sustainability after printing, and applicability of <I>in vitro</I> cell culture. This study proposes a cell-laden collagen scaffold fabricated <I>via</I> cell-printing and tannic acid (TA) crosslinking process. The effects of the crosslinking agent (0–3wt% TA) in the cell-laden collagen scaffolds on physical properties and cellular activities using preosteoblasts (MC3T3-E1) were presented. Compared to the cell-laden collagen scaffold without TA crosslinking, the scaffold with TA crosslinking was significantly enhanced in mechanical properties, while reasonable cellular activities were observed. Concisely, this study introduces the possibility of a cell-printing process using collagen and TA crosslinking and <I>in vitro</I> cell culture for tissue regeneration.</P>