콩 및 당의 종류의 달리한 매실 콩아이스크림의 품질특성

이숙영,김아영,유지영,이중기,이향섭 중앙대학교 생활과학연구소 2003 생활과학논집 Vol.17 No.-

The purpose of this experiment was to compare the quality characteristics of soy ice creams prepared with soy protein isolate(SPI) or Jinpum-soybean, and different kinds of sweeteners of maltitol and sucrose, xylitol+sucrose, or malitiol. The viscosity of the ice cream mix containing xylitol+sucrose appeared the highest, and that from Jinpum-soybean was higher than that from SPI. The overrun of soy ice creams containing xylitol+sucrose was the highest, and the next was the samples containing maltitol+sucrose. The overrun values of Jinpum-soybean samples appeared higher than those of SPI samples. As for the case of the SPI samples, the melt-down percent was the highest in the sample of maltitol addition, and the next were maltitol+sucrose addition, xylitol+sucrose addition in order. The melt-down percent of Jinpum-soybean was the highest in the sample of maltitol+sucrose addition, and the next were maltitol addition, xylitol+sucrose addition in order. The higher the viscosity of samples, the lower the melt-down percent. In sensory characteristics, the beany flavor, flavor, mouthfeel, overall quality of Jinpum-soybean samples were evaluated better than those of SPI in general. The samples containing xylitol+sucrose evaluated better in beany flavor, mouthfeel, icy feel, and overall quality. The quality characteristics of the samples prepared with Jinpum-soybeans and xylitol+sucrose were evaluated the best.

“浮休子(부휴자)”를 내세운 成俔(성현)의 말하기와 그 의미 -『浮休子傳(부휴자전)』『浮休子談論(부휴자담론)』을 중심으로-

황아영 ( Young Ah Hwang ) 한국한문고전학회(구 성신한문학회) 2013 漢文古典硏究 Vol.27 No.1

성현이 부휴자라는 가상의 인물을 내세워 말하고 있는 『浮休子傳』 과 『浮休子談論』을 중심으로 부휴자의 말하기와 그 의미를 살펴보고자 하였다. 성현은 자탁전의 형식을 가진 『부휴자전』 에서 부휴자의 성품과 즐거움을 이야기하며 자신이 추구하는 이상적 인간상을 그려내었다. 그리고 寓言의 형식을 갖춘 『부휴자담론』은 이야기 방식에 따라 『雅言』, 『寓言』, 『補言』가지 양식으로 나뉘어져 있는데 각 양식마다 부휴자와 허구 인물, 역사인물을 등장 시킴으로써 현실문제에 대한 직설적인 화법을 피하여 자신의 주장을 내세우 고 있다. 성현이 자신을 드러내어 직접 말하지 않고 부휴자라는 인물을 내세워 말하 고자 한 것이 무엇인지를 살펴보면, 첫째로, 임금에 대한 강한 勸戒와 諷刺임을 알 수 있다. 부휴자를 통해 이전의 훈구관각파가 주장한 ‘임금은 하늘이다’ 라는 의견을 따르는 듯하지만, 그 이면에는 ‘임금은 다만 백성을 위한 하늘의 대리자임’을 강조하고 있으며 이렇게 간접화법을 통해 말함으로써 자신을 드 말하는 데에 따르는 화를 면하고자 하였다. 그리고 성현은 표면적으로 ‘재주와 능력은 배워서 얻을 수 있는 것이다’라고 말하는 듯하지만 결국 ‘능력 과 재주는 타고나는 것이며 쉽게 변할 수 없는 것’이라고 주장하며 자신의 타 고난 재능과 능력을 더욱 강조하고 있다. 그러면서 훈구관각파와 도학 사림파 사이에서 어느 한쪽의 편도 아닌 중간자적 입장의 정치적 견해를 밝히고 있음을 볼 수 있다. 성현은 당시의 시대적 상황으로 인해 직접 말하기 어려운 자신의 정치적 견해와 강한 자긍심을 간접적으로라도 드러내기 위하여 부휴 자라는 인물을 통해 주장을 펼친 것이라 볼 수 있다. This article scopes out a fictional charater - Buhyuja`s speaking and means in The story of Buhyuja and Discussion of Buhyuja written by Sung Hyun (1439-1504). Sung Hyun described Buhyuja, an ideal type of human character, with Buhyuja`s personality and enjoyment in an autobiographical essay The story of Buhyuja. Meanwhile, Discussion of Buhyuja composed of three type of fascicles: ‘Graceful Words’, ‘Foolish Words’ and ‘Complementary Words’. In Discussion of Buhyuja, fictional characters had appeared in each section so that contemporary issues had been described with indirect narrations, which purposed to escape punishments derived from direct and straightforward speaking. In accordance with direct speaking from imaginary persona and bitter satire on society in The story of Buhyuja and Discussion of Buhyuja, Sung Hyun had sincere remonstrance and satire on a king. Sung Hyun seemed to conform demand - ‘The king is the Heaven’. However rather, Sung Hyun actually emphasized a king is a representative of the Heaven only for the public. In addition, Sung Hyun looked like to follow an assertion - ‘Personal talent and ability are obtainable with learning’, though Sung Hyun, in fact, highlighted one`s natural ability inborn characterized as well as scarcely changed. On the other hand, Sung Hyun had stated a middle coursed view of political opinions without single-side-on stance. Eventually, Sung Hyun applied various speaking on a fictional charater - Buhyuja. Then, Sung Hyun directly expressed meaning of his political opinions and self-esteem against contemporary social situations.

재직자를 위한 4년제 대학 비즈니스컨설팅학과 교육과정 개발: 서울소재 H대학 사례를 중심으로

황영아(Hwang, Young-Ah),임욱빈(Leem, Wook-Bin) 한국경영교육학회 2020 경영교육연구 Vol.35 No.4

[연구목적] 본 연구는 재직자를 대상으로 하는 4년제 대학 비즈니스컨설팅학과의 교육과정 개발을 위해 수행되었다. [연구방법] 본 연구는 재직자 대상 직업교육과정 개발 모형에 관한 고찰을 통해 교육과정 개발 모형을 도출하고, 산업체 인사를 포함하는 교육과정개발위원회를 6차례 개최하여 환경 분석, 교육목표 선정 및 인재양성유형 설정, 직무모형 설정 및 직무 검증, 교과목 선정, 교육과정로드맵 도출 등의 절차에 따라 교육과정 개발을 실시하였다. [연구결과] 이상의 절차에 따라 학과의 주요 양성 인력 유형은 경영컨설턴트, 전략경영컨설턴트, 기술경영컨설턴트로 도출되었으며, 직무 설정 및 검증 절차를 통해 현장에서의 수행직무 20개와 과업 80개가 도출되었다. 이를 토대로 직무별 지식 · 기술 · 태도를 고려하여 30개의 교과목 선정을 완료하였으며, 컨설턴트로서 종합적 역량 배양을 위한 세미나 과목 2개를 포함하여 32개 교과목을 포함하는 비즈니스컨설팅학과의 교육과정 로드맵을 제시하였다. [연구의 시사점] 컨설턴트와 관련한 기존 연구들은 컨설턴트의 역량을 규명하거나 컨설턴트 역량이 성과에 미치는 영향력에 초점을 둔 연구가 주로 이루어졌으나 교육적 관점에서 이루어진 연구는 전무한 실정이다. 본 연구는 재직자 대상 직업교육과정 개발 모형에 기반하여 체계적인 절차에 따라 컨설턴트 양성을 위한 교육과정을 개발함으로써 컨설턴트 양성을 위한 교육훈련의 토대를 제공할 것으로 기대되어진다. [Purpose] This study was conducted to develop a curriculum of a four- year college business consulting department for employees. [Methodology] The curriculum development model of this study was derived through consideration of the vocational curriculum development model. And the curriculum development committee, which includes industry personnel, was held six times to develop curriculum according to procedure such as environmental analysis, setting educational goal, job model setting, job verification, subjects selection, drawn the curriculum roadmap. [Findings] Through the job setting and verification procedures, 20 job performances and 80 tasks in the field were drawn. Based on this, 30 subjects were selected considering the knowledge, skills, and attitudes of each job. Lastly, H University’s Business consulting department curriculums designed consists of a 32 subjects. Among subjects, two capstone design subjects were established to develop expert competencies. [Implications] This study provided the foundation for education and training for consultants by developing a curriculum according to a systematic procedure based on the vocational curriculum development model for incumbents.

Paricalcitol attenuates lipopolysaccharide-induced inflammation and apoptosis in proximal tubular cells through the prostaglandin E₂ receptor EP4

( Yu Ah Hong ),( Keum Jin Yang ),( So Young Jung ),( Yoon Kyung Chang ),( Cheol Whee Park ),( Chul Woo Yang ),( Suk Young Kim ),( Hyeon Seok Hwang ) 대한신장학회 2017 Kidney Research and Clinical Practice Vol.36 No.2

Background: Vitamin D is considered to exert a protective effect on various renal diseases but its underlying molecular mechanism remains poorly understood. This study aimed to determine whether paricalcitol attenuates inflammation and apoptosis during lipopolysaccharide (LPS)-induced renal proximal tubular cell injury through the prostaglandin E₂ (PGE₂) receptor EP4. Methods: Human renal tubular epithelial (HK-2) cells were pretreated with paricalcitol (2 ng/mL) for 1 hour and exposed to LPS (1 μg/mL). The effects of paricalcitol pretreatment in relation to an EP4 blockade using AH-23848 or EP4 small interfering RNA (siRNA) were investigated. Results: The expression of cyclooxygenase-2, PGE₂, and EP4 were significantly increased in LPS-exposed HK-2 cells treated with paricalcitol compared with cells exposed to LPS only. Paricalcitol prevented cell death induced by LPS exposure, and the cotreatment of AH-23848 or EP4 siRNA offset these cell-protective effects. The phosphorylation and nuclear translocation of p65 nuclear factor-kappaB (NF-κB) were decreased and the phosphorylation of Akt was increased in LPS-exposed cells with paricalcitol treatment. AH-23848 or EP4 siRNA inhibited the suppressive effects of paricalcitol on p65 NF-κB nuclear translocation and the activation of Akt. The production of proinflammatory cytokines and the number of terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling-positive cells were attenuated by paricalcitol in LPS exposed HK-2 cells. The cotreatment with an EP4 antagonist abolished these anti-inflammatory and antiapoptotic effects. Conclusion: EP4 plays a pivotal role in anti-inflammatory and antiapoptotic effects through Akt and NF-κB signaling after paricalcitol pretreatment in LPS-induced renal proximal tubule cell injury.

Light-induced isomerization dynamics of a cyanine dye in the modulus-controlled regime

Jee, Ah-Young,Park, Seohyun,Lee, Minyung Royal Society of Chemistry 2011 Physical chemistry chemical physics Vol.13 No.33

<P>The <I>trans</I>–<I>cis</I> isomerization of an excited molecule converts light energy into mechanical motion, which interacts cooperatively with its surroundings. To understand such a photodynamic process in solids, we investigated the internal twisting motion of 1,1′-diethyl-2,2′-cyanine iodide (DCI) in a series of poly(alkyl methacrylate) (PAMA) polymers by measuring the Young's moduli of the polymers with atomic force microscopy nanoindentation and the fluorescence lifetimes of the dye with time-correlated single photon counting. We found that the isomerization rate constant obtained from the average lifetime correlated well with the mechanical property of the matrix. Our results show that the light-induced molecular motion lies in the modulus-controlled regime in which the polymer matrix not only provides a rigid environment for the dynamics of the molecules but also participates actively in the motion. The concept of elastic modulus may be applicable to molecular rotor dynamics in any synthetic polymer and, in principle, can be extended to biopolymers such as proteins or DNA.</P> <P>Graphic Abstract</P><P>Twisting motion of a photoexcited cyanine dye in poly(alkyl methacrylate) polymers correlated well with the Young's modulus of the medium. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1cp20835g'> </P>

침 시술로 발생한 Non-O1, Non-O139 Vibrio cholerae에 의한 패혈증

임태섭,지아영,이중희,장수연,김인수,김영주,김범경,김승업,박준용,안상훈,한광협,김도영 Ewha Womans University School of Medicine 2013 EMJ (Ewha medical journal) Vol.36 No.S

Vibrio cholerae is mainly known to cause gastrointestinal infection after seawater exposure or raw seafood intake. It is rarely reported to cause cellulitis or sepsis, but threre has been no known case after acupuncture. Herein, We report a 56-year-old cirrhotic patient of non-O1, non-O139 Vibrio cholerae septicemia caused by cellulitis of both lower extremities after acupuncture.

Amino-Functionalized Mesoporous Silica Particles for Ocular Delivery of Brimonidine

Kim, Se-Na,Ko, Song Ah,Park, Chun Gwon,Lee, Seung Ho,Huh, Beom Kang,Park, Yoh Han,Kim, Young Kook,Ha, Ahnul,Park, Ki Ho,Choy, Young Bin American Chemical Society 2018 MOLECULAR PHARMACEUTICS Vol.15 No.8

<P>To treat glaucoma, conventional eye drops are often prescribed. However, the eye drops have limited effectiveness as a result of low drug bioavailability due to their rapid clearance from the preocular space. To resolve this, we proposed amino-functionalized mesoporous silica (AMS) particles as delivery carriers of the glaucoma drug, brimonidine. Because of the presence of mesopores, brimonidine (BMD) could be encapsulated in the AMS with a loading amount of 41.73 μg/mg (i.e., drug loading capacity of about 4.17%) to give the BMD-AMS, which could release the drug in a sustained manner over 8 h. BMD-AMS was also shown to be mucoadhesive due to the presence of both hydroxyl and amino groups in the surface, allowing for formation of hydrogen bonds and an ionic complex with the mucin, respectively. Therefore, when topically administered to rabbit eyes in vivo, BMD-AMS could reside in the preocular space for up to 12 h because of its adherence to the mucous layer. To assess in vivo efficacy, we examined the variance in intraocular pressure (IOP) and brimonidine concentration in the aqueous humor (AH) after applying BMD-AMS to the eye, which was compared with that induced by Alphagan P, the marketed brimonidine eye drops. For BMD-AMS, the duration in the decrease in IOP and the area under the drug concentration in the AH-time curve (AUC) were 12 h and 2.68 μg·h/mL, respectively, which were about twice as large as those obtained with Alphagan P; this finding indicated enhanced ocular bioavailability of brimonidine with BMD-AMS.</P> [FIG OMISSION]</BR>

실험적 진폐증에서 투여약제에 따른 면역학적 병리학적 조직변화

윤임중,임현우,노영만,오상용,정장영,임영,김경아 가톨릭 대학 산업의학 쎈타 산업의학연구소 1993 韓國의 産業醫學 Vol.32 No.2

To access the effects of some drugs such as piperazine phosphare, azathioprine and allopurinol in the experimental pneumoconiosis, 263 rats weighted 240-320 gm was divided into the control and eight experimental groups. To each group, the turbid solution mixed free silica, talc and natural coal dust of 50 mg in 0.8 ml saline were instilled intratracheally. At the begining and 5th week of experiment, piperazine phosphate(8mg/week orally), aspirin(1.5mg/day intramuscularly), azathioprine(25mg/day orally) and allopurinol(1.5mg/day orally) were administered simultaneously, while the dust turbid solution was only given to the control group. For each group the change of body weight. dry right lung weight, cellularity including total cell, macrophage, lymphocyte and neurtrophil in bronchoalveolar lavage fluid, superoxide ion, hydroxyproline, leukotriene B₄, tumor necrotsis factor, prostaglandin E₂were examined, and observed the pathological chages in lung tissue. The results were as follow : 1. The larger amount of their instilled dust and the longer observation period, the severer pathological findings were found in the lung tissue of each experimental group. 2. The body and dry right lung wight was not significantly changed in the experimental groups compared with the control group. 3. The number of total cell in bronchoalveolar lavage fluid was markedly less in the experimental group than the control one, while no significant difference was found in the percent alveolar macrophages and lymphocytes in both groups. However, the percent of neutrophiles was usually lower than in the control group. 4. The amount of superoxide ion was frequently less in the experimental group compared with the control one. 5. The amount of hydroxyproline was significantly lower in the experimental group than in the control one. 6. The amount of leukotriene B₄was usually less in the drug administered group than in the control one. 7. The amount of tumor necrotic factor was also frequently lower in each experimental group than in the control one. 8. The amount of prostaglandin E₂was usually higher in each experimental group than in the control one.

In vivo study for the hemostatic efficacy and foreign body reaction of a new powder-type polysaccharide hemostatic agent

Yoonhyeong Byun,Eun Jin Kim,Areum Lee,Young-Ah Suh,Hee Ju Sohn,Jung Min Lee,Jae Seung Kang,Yoo Jin Choi,Youngmin Han,Hongbeom Kim,Wooil Kwon,Jin-Young Jang 대한외과학회 2022 Annals of Surgical Treatment and Research(ASRT) Vol.102 No.2

Purpose: Various hemostatic agents have been introduced in therapy as postoperative bleeding is a poor prognostic factor for postoperative outcomes. These products can be divided into those that directly promote the hemostatic cascade and those that physically form a barrier by absorbing blood. The latter, powder-type hemostatic agents have the advantages of being inexpensive and more absorbable with less foreign body reactions (FBRs) and are applicable to a relatively wide area. This study was conducted to verify the safety and efficacy of a newly invented polysaccharide product (OOZFIX, Theracion Biomedical), which improves blood absorption and hemostatic effects. Methods: Two separate animal experiments were performed. The first evaluated FBRs histologically at 3 days, 2 weeks, and 4 weeks, after implantation of OOZFIX in rats, and the second compared hemostatic performance of OOZFIX and Arista AH (Bard) in the porcine liver punch biopsy model. Results: We found minimal FBRs in the 3-day group and no reactions in both the 2-week and 4-week groups after implantation of hemostatic agents. The time to hemostasis of OOZFIX was not significantly different from that of Arista AH (median [interquartile range]: 9 [6–10] minutes vs. 8 [6–10] minutes, respectively; P = 0.522). When comparing the serial bleeding grade tendency, there was no statistical difference between OOZFIX and Arista AH (P = 0.656). Conclusion: OOZFIX caused a minimal FBR that disappeared within 2 weeks in vivo, and its hemostatic performance was comparable with that of an existing agent, Arista AH. Further clinical studies are required in the future.

갑상선 유두암이 병발된 가족성 대장 용종증 1예

백종현,소창배,이은영,이지숙,신은경,박은호,서정아,양재홍,송준영,박선자,박요한,최영식 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome, typically characterized by multiple colorectal adenomas and increased incidence of colorectal carcinomas if it is not treated. Moreover, a variety of extracolonic manifestation are seen. The prevalence of thyroid tumors developing in patients with FAP is about 1∼2%. Generally, papillary thyroid cancer indicates low mortality but ,however, as people get older, the cancer becomes more aggressive. So, the operation is required. Recently we experienced a case of FAP, presenting with papillary thyroid carcinoma, and reported with a brief review of literatures.