만성 동맥 폐색증 환자에서 Cilostazol(Pletaal^�)투여시 자각증상 및 혈액 동태에 미치는 영향

김영일,노승무,장일성,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.1

At department of Surgery, Chungnam National University Hospital, from March 1991 to October 1991, a new platelet aggregation inhibitor, cilostazol, with a vasodilating action, was administered orally in daily doses of 200mg for 8 weeks in chronic arterial occlusive diseases. After administration, the clinical effects of cilostazol were observed in 10 patients with thromboangiitis obliterans and arteriosclerosis obliterans. The results were as follows: 1. The overall improvement rate of the diseases was 80 percent. 2. The adverse effects of cilostazol were headache in one patient, indigestion in one patient, and overall safety rate was 80 percent. It can be concluded that cilostazol is useful in the treatment of chronic arterial occlusive disease.

종양치료시 항종양제에 의한 조혈기 장애에 대한 Cephalanthin^(R)의 임상적 평가

김영일,노승무,장일성,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

The clinical effect of Cephalathin Tab^(R). was observed in 33 cases with chemotheraphy in the cancer patients. Cephalathin Tab^(R). was administered per oral 3-6mg daily in three divided for an average of 58 days. The overall effectiveness was 87% and there was no side effect of Cephalathin Tab^(R). In conclusion, Cephalatin Tab^(R). was safe and effective drug for management of hematologic disorder by the anticancer agent.

선천성 거대결장증 진단에 필요한 조직화학염색 : Rapid Acetylcholinesterase Staining

설지영,김제룡,김진만,장일성 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

Hirschsprung's disease is a congenital absence of ganglion cells in the Meissner's and Auerbach's plexuses of the colon. The definitive diagnosis of the disease can only be based on histologic examination of bowel wall biopsies demonstrating aganglionosis. To distinguish Hirschsprung's disease from other causes of contipation and megacolon, it is helpful to use histologic examination with routine hematoxylin and eosin (H&E) staining and acetylcholinesterase (AChE) special histochemical staining techniques. With H&E staining, the difficulties may arise in the hypoganglionic area of the transition zone, or in hypoganglionosis or neuronal intestinal dyspiasia. The AChE technique provides reliable identification of ganglion cells by staining nerve filaments in close proximity to the ganglion cells. However, the conventional AChE technique takes about 2 hours for the examination of specimens, so it is not suitable for intraoperative examination. Using a rapid AChE histochemical staining technique, it is possible to produce staining of cholinergic fibers in 20 minutes. It should enable the surgeon to use it selectively during operation and to support or refute the H&E findings.

조기 위암의 임상적 고찰

장일성,김영일 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

This report is a clinical review of 50 cases of early gastric cancer that were treated and followed during 6 years from June. 1985 to June 1990. 1. The peak incidence age was 50 decade(38%), the mean age was 50 years, the ratio of male to female was 3:2. 2. The preoperative diagnostic rate was 52% by double conrast and 60% by endoscopy and biopsy. 3. The most common size of lesions was 1.1-2cm(32%) the smaller of lesion, the greater incidence of invasion rate to submucosa but no relation to lymph node matastasis rate. 4. The most common type of lesion was IIc(28%), the depressed type(III, IIb+c, IIc) was lymph node metastasis, but the elevated type and flat type was not lymph node matastasis. 5. The most common histological type was moderate differentiated and signet-ring cell types(32.5%) the most common type of metastatic rate was moderate differentiated type (30.7%), the badder of differentiated type, the greater incidence of metastatic rate to lymph node. 6. The common sites were lower third and lesser curvature(50%). The greater incidence of metastatic rate and invasion rate to submucosa the site of posterior wall was. 7. The rate of lymph node matastasis was 6.3% in mucosa, 26.4% in submucosa and 20% in total. 8. Follow up studies were possible in 45 cases, in these 1 case was died, 1 case was recurred but alive.

위장관 수술후 소화 불량증상을 호소하는 환자에 종합소화효소제 베아제정의 임상효과

손기섭,배진선,장일성,윤완희,김영일 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

The Clinical effect of Bearse Tab. was observed in 58 cases with postoperative indigestion. The results were as follows : 1. Overall evaluation of treatment revealed effective in 80.9% (34/42) after the GI surgery, improvement rate were 77.8%(23/31). 2. At the postoperative abdominal distention, improvement rate were high rate (92%). 3. There was no side effect of Bearse Tab. In Conclusion, Bearse Tab was safe and effective for management of postoperative indigestion state.

High-temperature Thermal Decomposition of Cs-adsorbed CHA-Cs and CHA-PCFC-Cs Zeolite System, and Sr-adsorbed 4A-Sr and BaA-Sr Zeolite System

Eil-Hee Lee,Ji-Min Kim,Hyung-Ju Kim,Ik-Soo Kim,Dong-Yong Chung,Kwang-Wook Kim,Keun-Young Lee,Bum-Kyoung Seo 한국방사성폐기물학회 2018 방사성폐기물학회지 Vol.16 No.1

본 연구는 고온 열분해를 통한 Cs, Sr 등 고방사성핵종의 고정화를 위하여 각각 Cs이 흡착된 CHA (K형 Chabazite zeolite)-Cs, CHA-PCFC (potassium cobalt ferrocyanide)-Cs 및 Sr이 흡착된 4A-Sr, BaA-Sr 등의 제올라이트 계에서 TGA 및 XRD에 의한 배소 온도 변화에 따른 상변환을 고찰하였다. CHA-Cs 제올라이트 계의 경우 900℃ 까지는 CHA-Cs의 형태를 유지하고 있으며, 1,000℃에서 무정형 단계를 거친 후 1,100℃에서 pollucite (CsAlSi2O6)로 재결정 되었다. 반면에 CHA-CFC-Cs 제올라이 트 계는 700℃ 까지는 CHA-PCFC-Cs 형태를 유지하고 있으나, 900∼1,000℃ 사이에서 구조가 파괴되어 무정형으로 상변환 된 후 1,100℃에서 pollucite로 재결정 되었다. 한편 4A-Sr 제올라이트 계의 경우 700℃ 까지는 4A-Sr의 구조를 유지하고 있 으며, 800℃에서 무정형으로 상변환 된 다음 900℃에서는 Sr-feldspar (SrAl2Si2O8, hexagonal)으로, 1,100℃에서 SrAl2Si2O8 (triclinic)로 재결정 되었다. 그러나 BaA-Sr 제올라이트 계의 경우는 500℃ 이하부터 구조가 파괴되기 시작하여 500∼900℃ 에서 무정형 단계를 거친 후, 1,100℃에서 Ba/Sr-feldspar (Ba0.9Sr0.1Al2Si2O8 및 Ba0.5Sr0.5Al2Si2O8 공존)로 재결정 되었다. 상기 제올라이트 계 모두 온도 증가에 따라 탈수/(분해)→ 무정형→ 재결정의 단계를 거쳐 광물상으로 재결정 되었으며, 고온 열 분해 과정에서의 Cs 및 Sr의 휘발성, 침출성 등의 추가 연구가 요구되지만 각 제올라이트 계에 흡착된 Cs 및 Sr은 pollucite나 Sr-feldspar, Ba/Sr-feldspar 등으로 광물화 하여 Cs과 Sr을 배소체/(고화체) 내에 완전히 고정화 시킬 수 있을 것으로 보인다. For the immobilization of high-radioactive nuclides such as Cs and Sr by high-temperature thermal decomposition, this study was carried out to investigate the phase transformation with calcined temperature by using TGA (thermogravimetric analysis) and XRD (X-ray diffraction) in the Cs-adsorbed CHA (chabazite zeolite of K type)-Cs and CHA-PCFC (potassium cobalt ferrocyanide)-Cs zeolite system, and Sr-adsorbed 4A-Sr and BaA-Sr zeolite system, respectively. In the case of CHA-Cs zeolite system, the structure of CHA-Cs remained at up to 900℃ and recrystallized to pollucite (CsAlSi2O6) at 1,100℃ after undergoing amorphous phase at 1,000℃. However, the CHA-CFC-Cs zeolite system retained the CHA-PCFC-Cs structure up to 700℃, but its structure collapsed in 900~1,000℃, and then transformed to amorphous phase, and recrystallized to pollucite at 1,100℃. In the case of 4A-Sr zeolite system, on the other hand, the structure of 4A-Sr maintained up to 700℃ and its phase transformed to amorphous at 800℃, and recrystallized to Sr-feldspar (SrAl2Si2O8, hexagonal) at 900℃ and to SrAl2Si2O8 (triclinic) at 1,100℃. However, the BaA-Sr zeolite system structure began to break down at below 500℃, and then transformed to amorphous phase in 500~900℃ and recrystallized to Ba/Sr-feldspar (coexistence of Ba0.9Sr0.1Al2Si2O8 and Ba0.5Sr0.5Al2Si2O8) at 1,100℃. All of the above zeolite systems recrystallized to mineral phase through the dehydration/(decomposition)→ amorphous → recrystallization with increasing temperature. Although further study of the volatility and leachability of Cs and Sr in the high-temperature thermal decomposition process is required, Cs and Sr adsorbed in each zeolite system are mineralized as pollucite, Sr-feldspar and Ba/Sr-feldspar. Therefore, Cs and Sr seen to be able to completely immobilize in the calcining wasteform/(solidified wasteform).

조기위암의 내시경적 고찰

김진희,이충식,배진선,조준식,임의혁,정현용,김영건,이헌영,육은주,김성걸,노승무,장일성 대한소화기내시경학회 1995 Clinical Endoscopy Vol.15 No.2

In order to decide on appropriate treatment strategy against gastric cancer, an accurate preoperative evaluation of the depth of cancer invasion is essential. We studied 165 cases(19%) of early gastric cancer among 706 cases of gastric cancer. resected over a 6 year period. A retrospective study of early gastric cancer was done to evaluate the endoscopic accuracy and lymph node metastasis status, the following results were obtained: 1) The proportion of EGC according to macroscopic type was 68.5% of depressed type(II, III, IIa+III, IIc+III, III+IIc, IIb+IIc), 26% of elevated type(I, IIa, IIa+ IIb, IIa+IIc), 5.5% of flat type(IIb). 2) In the view of accuracy of endoscopic diagnosis, the rate of accurate diagnosis suitable for postoperative macroscopic type was 37.5%, the rate of unsuitable typed EGC was 33.3%, overestimation(diagnosed to AGC) was 20.6% and underestimation(diagnosed to benign diseases)was 8.6%. Overall accuracy of endoscopic diagnosis was 70.8%. 3) The cases confined to the mucosa were 40.6% and others were submucosal cancers(59.4%). 4) Positive lymph node metastasis was found in 1.5% of M-cancer and 18.4% of SM-cancer(overall 11.5%). 5) Node positive rate of differentiated cancer was 10.5%, undifferentiated carcinoma was 15.4%. There was no signficant difference in frequency of nodal metastasis according tumor size and macroscopic type. 6) Tumors which satisfy the following criteria may not metastasize to lymph nodes:(1) confined to the mucosa; (2) less than 2.0cm in diameter; (3) macroscopically elevated or flat; (4) histologically well or moderately differentiated.

노년층 피부질환의 분포에 관한 임상적 관찰

김병수,이승철,은희철,유재학,정승용,이일수,여운철,김영걸,고우석,김계정,최호철,이시원 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.5

Background: It is a trend that the average life span is prolonged in proportion to the advance of socio-economy and medical science. Consequently, the number of elderly patients with skin diseases is increasing. Objective: This study was performed to see the change of patterns of skin diseases in elderly patients. Methods: One thousand four hundred and twenty elderly patients, over the age of 65, who visited the departments of dermatology and in five hospitals, from January 1, 1997 to December 31, 1997 were selected. We surveyed the frequeney of skin disease by types and the distributions by month, season and age. Results: The results were as follows; 1. The frequent skin diseases were herpes zoster and postherpetic neuralgia (12.3%), fungal infection (11.3%), pruritus (9.2%), contact dermatitis (6.8%), and seborrheic dermatitis (5.7%). 2. The most frequent was herpes zoster and postherpetic neuralgia in January, February, March, April, June, August and October, in January, July, September and December, fungal infection; in May, contact dermatitis; in November, pruritus. 3. The most frequent skin desease was herpes zoster and postherpetic nueralgia in spring, summer and winter; in autumn, fungal infection. 4. The most frequent skin disease for the 65-74 aged-group was herpes zoster and postherpetic neuralgia; for the over 85 aged group, herpes zoster and postherpetic neuralgia. Conclusion: The results showed that, in contrast to previous studies, herpes zoster and postherpetic neuralgia increased in elderly patients. These findings may be helpful for the government and medical centers to plan and establish a management system on the skin diseases of elderly patients.

Thermal Decomposition of Chabazite-Cs and Chabazite-PCFC-Cs Zeolite

Eil-Hee Lee,Ji-Min Kim,Maeng-Kyo Oh,Min-Jeong Kim,Keun-Young Lee,Kwang-Wook Kim,Hyung-Ju Kim,Ik-Soo Kim,Dong-Yong Chung,Jei-Kwon Moon,Jong-Won Choi 한국방사성폐기물학회 2017 한국방사성폐기물학회 학술논문요약집 Vol.2017 No.05

스테인레스 스틸와이어 메쉬에 의해 보강된 구형교각의 내진 성능평가

김성훈(Kim Sung Hoon),김대곤(Kim Dae Kon),김현일(Kim Hyun Eil),김영규(Kim Young Kyu) 대한토목학회 2005 대한토목학회 학술대회 Vol.2005 No.10