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한국개비자(Cephalotaxus koreana)의 Harringtonine 과 Homoharringtonine에 관한 연구
이연,박두천,박호일,주우홍,이현채,신동수 昌原大學校 基礎科學硏究所 1996 基礎科學硏究所論文集 Vol.8 No.-
한국산 개비자로부터 alkaloid계통의 성분인 harringtonine과 homoharringtonine의 혼합물을 추출하여 한국산 개비자의 잎, 줄기, 뿌리에서의 harringtonine과 homoharringtonine의 함량은 고속 액체 크래마토그래피에 의해 결정하였다. 두물질의 함량은 서식지, 식물의 부위에 따라 상이하였다. Harringtonine의 함량은 줄기보다 잎과 뿌리에서 높았고, homoharringtonine의 함량은 harringtonin 함량보다 낮았다. 팔공산, 덕유산, 백양산, 지리산 및 남해에서의 잎의 homoharringtonine 함량은 줄기와 뿌리에서 높게 나왔으며, 조계산과 진도에서는 잎의 함량이 뿌리와 줄기에서 보다 낮았다. Harringtonine and homoharringtonine known as anti-cancer agents were isolated from Korean native plumyew (Cephalotaxus koreana). The contents of harringtonine and homoharringtonine in the needles, stems, and roots of Korean native plumyew were determined by high performance liquid chromatography (HPLC). The contents of both compounds varied with the site of location and the part of plant. The content of harringtonine was higher in needles and roots than in stems, whereas the content of homoharringtonine was lower than harringtonine. Homoharringtonine contents in needles at Mt. Palgong, Mt. Dukyu, Mt. Baekyang, Mt. Jiri, and Namhae were higher than in stems and roots. But homoharringtonine contents in needles at Mt. Jokye and Jindo were lower than in stems and roots.
문상돈,김연직,임익태,박찬우 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-
As a technology to machine the 3-dimensional shapes of general metal material more flexibly, machining technologies such as metal cutting, grinding, etc have been steadily improved in their accuracy as well. However, the working method using machining technologies are restricted in terms of surface roughness, metal working accuracy and working hours, if a workpiece has an irregular 3-dimensional shape. Magnetic abrasive finishing process is also one of the super-precision machining technologies which proceed with the finishing metal working of precision working piece using the action of magnetic field and the mixed type magnetic abrasive. However, such studies only focus on the improvement of machining accuracy but are still incomplete in investigating the roundness. This study aims to realize the high accuracy finishing machining focusing on the roundness after magnetic abrasive finishing process of circular workpiece and the surface roughness of precision machining surface.
誘導電動機의 驅動을 위한 負荷轉流型 인버터에 관한 硏究
소용철,이우춘,정연택 明知大學校 産業技術硏究所 1991 産業技術硏究所論文集 Vol.10 No.-
Investigation of the driving range of the induction motor which is operated by using a load commutated inverter has been carried out in this paper. It is shown that capacitance of the commutation capacitor can be reduced by the forced-com-mutation driving up to a half range of normal frequency in the low frequency in the low frequency range when to start the motor drive.
진정법을 이용한 치과치료 시 편도선의 크기가 행동에 미치는 영향
김현지,백광우,마연주,정영정 大韓小兒齒科學會 2010 大韓小兒齒科學會誌 Vol.37 No.3
본 연구에서는 진정법을 이용한 치과치료에서 소아환자의 편도선 크기가 진정법 중 환자의 행동에 미치는 영향을 평가하기 위해 진정법으로 치과치료를 받은 소아환자 35명의 진정기록지를 분석하였다. 진정법은 chloral hydrate 50 mg/kg, hydroxyzine 1 mg/kg를 경구투여하고, 치료 중 50% 아산화질소-산소 흡입 진정 및 필요에 따라 midazolam의 점막하투여(0~0.3 mg/kg)를 병행하는 방법으로 시행되었으며, 편도선의 크기는 Brodsky 분류법을 이용하여 4그룹으로 분류하였다. 환자의 진정 기록지를 분석하여 다음과 같은 결과를 얻었다. 1. 진정법 중 행동 반응은 수면, 움직임, 울음, 전반적 행동 모두에서 편도선 크기가 클수록 낮은 지수(negative behavior)를 보였다(p<0.05). 2. 편도선의 크기는 진정법 중 구호흡과 유의한 연관성을 보였으나(p<0.05), 진정법 중 코골이, 기침과는 유의한 연관성을 보이지 않았다(p>0.05). 3. 편도선의 크기가 큰 환자일수록 midazolam의 점막하투여량이 유의하게 증가하였다(p<0.05). The purpose of this study was to evaluate the effect of children's tonsil size on the behavior during pediatric dental sedation. The sedation records of thirty five children were examined in this study. All the sedations had been performed using chloral hydrate/hydroxyzine, nitrous oxide/oxygen or/and submucosal midazolam, and the subjects were divided into 4 groups according to their tonsil size using Brodsky's tonsil classification. The results were as follows: 1. The patients with enlarged tonsils showed negative behaviors in all behavior rating aspects(sleep, movement, crying, overall behavior) during sedation than those with normal tonsils(p<0.05). 2. Enlarged tonsils were correlated with mouth breathing(p<0.05) but not with snoring and coughing(p>0.05) during sedation. 3. For the patients with enlarged tonsils, significantly higher doses of midazolam were administered during sedation than for those with normal tonsils(p<0.05).
Predictive factors of postherpetic neuralgia in patients with herpes zoster
( Yong Yon Won ),( Seung Hee Loh ),( Dong Woo Suh ),( Bark Lynn Lew ),( Woo Young Sim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2
Background: Postherpetic neuralgia(PHN) is the most common complication of herpes zoster(HZ) .Effective prophylaxis is currently lacking, in spite of importance of prevention. Identifying the predictive factors of PHN is critical to lower the incidence of PHN in HZ patients. Objectives: To evaluate predictors of PHN in HZ patients. Methods: A retrospective study of 1,030 HZ patients whohad been treated at the dermatology department of our hospital was performed.. Primary dermatome region, age, sex, immune status, the period taken from pain onset to treatment, antiviral medications, steroid medication, amitriptyline medication, gabapentin medication and nortriptyline medication were evaluated as potential predictors of PHN. Results: We used logistic regression for this study. In the multivariable regression model, advanced age [odds ratio(OR)=1.029, confidence interval(CI)=1.014-1.045; P=0.000], the period taken from pain onset to treatment [OR=1.081, CI=1.041-1.122; P=0.000], missed amitriptyline medication[OR=1.904, CI=1.193-3.039; P= 0.007] and missed antiviral medication[OR=1.981, CI= 1.060-3.703; P=0.032] were significantly associated with the development of PHN. Conclusion: It is well-recognized that older age and greater severity of acute pain at rash onset increase therisk of developing PHN. Our study suggests that older age, missed amitriptyline medication, the period taken from pain onset to treatment, missed antiviral medication may play a role in the development of PHN.
김연래(Yon-Lae Kim),윤영우(Young-Woo Yoon),정재용(Jae-Yong Jung),이정우(Jeong-Woo Lee),정진범(Jin-Beom Chung) 대한방사선과학회(구 대한방사선기술학회) 2021 방사선기술과학 Vol.44 No.4
A quality assurance of computed tomography(CT) have done seven items that were water attenuation coefficient, noise, homogeneity, spatial resolution, contrast resolution, slice thickness, artifact using by standard phantom. But there is no quality assurance items and methods for CT simulator at domestic institutions yet. Therefore the study aimed to access the CT dose index(CTDI), table tilting, image distortion, laser accuracy, table movement accuracy and CT seven items for CT simulator quality assurance. The CTDI at the center of the head phantom was 0.81 for 80 kVp, 1.55 for 100 kVp, 2.50 for 120 ㎜, 0.22 for 80 kVp at the center of the body phantom, 0.469 for 100 kVp, and 0.81 for 120 kVp. The table tilting was within the tolerance range of ±1.0° or less. Image distortion had 1 ㎜ distortion in the left and right images based on the center, and the laser accuracy was measured within ±2 ㎜ tolerance. The purpose of this study is to improve the quality assurance items suitable for the current situation in Korea in order to protect the normal tissues during the radiation treatment process and manage the CT simulator that is implemented to find the location of the tumor more clearly. In order to improve the accuracy of the CT simulator when looking at the results, the error range of each item should be small. It is hoped that the quality assurance items of the CT simulator will be improved by suggesting the quality assurance direction of the CT simulator in this study, and the results of radiation therapy will also improve.