Study on diamond thin film deposited on graphite substrate by different pretreatment methods

Hung-Yin Tsai 한양대학교 세라믹연구소 2012 Journal of Ceramic Processing Research Vol.13 No.S1

Nanocrystalline diamond thin film has been deposited on a graphite substrate by hot filament chemical vapor deposition system. The characteristics of diamond thin film growth on a graphite sheet were evaluated depending on the pretreatment methods which increase the nucleation density. Four kinds of pretreatments were studied including mechanical abrasion by nano-diamond powders, ultrasonication of graphite in solvents with nano-diamond powder suspension, electrophoretic deposition, and pretreatment with polyethyleneimine (PEI) to change the surface polarity, allowing the adsorption of negatively charged diamond particles onto the substrate surface. Electrophoresis and PEI pretreatment methods were found to be favorable of the diamond deposition to the graphite sheet. The serial process of the PEI-pretreatment and immersion into acetone solution of diamond nano-powders was concluded as an optimal condition, resulting in 100% film coverage of diamond film with the average grain size of 0.7-0.8 µm on the graphite sheet. It can be suggested that the diamond film deposited on graphite could replace current SiC deposited graphite carrier in MOCVD process.

Prediction of the compressive and tensile strength of HPC concrete with fly ash and micro-silica using hybrid algorithms

Yin, Hang,Liu, Shuxian,Lu, Shasha,Nie, Wei,Jia, Baoxin 테크노프레스 2021 Advances in concrete construction Vol.12 No.4

Evaluating the impact of fly ash (FA) and micro-silica (MS) on the tensile (TS) and compressive strength (CS) of concrete in different ages provokes to find the effective parameters in predicting the CS and TS, which not only could be usable in the practical works but also is extensible in the future analysis. In this study, in order to evaluate the effective parameters in predicting the CS and TS of concrete containing admixtures and to present a fitted equation, the multivariate adaptive regression splines (MARS) method has been used, which could find a relationship between independent and dependent variables. Next, for optimizing the output equation, hybrid genetic algorithm (GA), particle swarm optimization (PSO), and grey wolf optimization (GWO) methods have been utilized to find the optimal conclusions. It could be concluded that for both predictions of CS and TS, all models have the coefficient of determination (R²) larger than 0.949 and 0.9138, respectively. Furthermore, between three hybrid algorithms, MARS-PSO could be proposed as the best model to obtain the most accuracy in the prediction of CS and TS. The usage of hybrid MARS-PSO techniques causes a noticeable improvement in the prediction procedure.

Whole-liver Radiotherapy Concurrent with Chemotherapy as a Palliative Treatment for Colorectal Patients with Massive and Multiple Liver Metastases: a Retrospective Study

Yin, Hang,Lu, Kai,Qiao, Wen-Bo,Zhang, Hai-Yang,Sun, Di,You, Qing-Shan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4

The purpose of this study was to investigate whether whole-liver radiotherapy plus a tumor-boost dose with concurrent chemotherapy is beneficial for colorectal cancer patients with massive and multiple liver metastases. From January 2007 to December 2012, 19 patients who exhibited massive (with a longest diameter > 5 cm) and invasive liver metastases and multiple metastases were treated with radiotherapy and concurrent chemotherapy. The total radiation dose was 53.4 Gy (range 38.8 Gy-66.3 Gy). All of the patients received a continuous intravenous dose of 5 fluorouracil (5-FU) 225 mg/m2 concurrently with radiation. The median survival time was 19 months. The 1- and 2- year overall survival rates were 78.3% and 14.3%, respectively. Of all of the patients who presented with abdominal pain, 100% experienced a decrease in pain. Decreases in the rates of ascites and jaundice were confirmed by ultrasound and bilirubin levels. No cases of Grade 4 or 5 acute or late toxicity were recorded. There were only two cases of Grade 3 toxicity (elevated bilirubin). These data provide evidence that whole-liver radiotherapy plus a tumor-boost dose with concurrent chemotherapy is beneficial for colorectal cancer patients with massive and multiple liver metastases.

Variations in Practice among Asia–Pacific Surgeons and Recommendations for Managing Cervical Myelopathy: The First Asia–Pacific Spine Society Collaborative Study

Jason Pui Yin Cheung,Prudence Wing Hang Cheung,Chee Kidd Chiu,Chris Yin Wei Chan,Mun Keong Kwan 대한척추외과학회 2019 Asian Spine Journal Vol.13 No.1

Study Design: Surgeon survey. Purpose: To study the various surgical practices of different surgeons in the Asia–Pacific region. Overview of Literature: Given the diversity among Asia–Pacific surgeons, there is no clear consensus on the preferred management strategies for cervical myelopathy. In particular, the role of prophylactic decompression for silent cervical spinal stenosis is under constant debate and should be addressed. Methods: Surgeons from the Asia–Pacific Spine Society participated in an online questionnaire comprising 50 questions. Data on clinical diagnosis, investigations and outcome measures, approach to asymptomatic and silent cervical spinal stenosis, guidelines for surgical approach, and postoperative immobilization were recorded. All parameters were analyzed by the Mantel–Haenszel test. Results: A total of 79 surgeons from 16 countries participated. Most surgeons used gait disturbance (60.5%) and dyskinetic hand movement (46.1%) for diagnosis. Up to 5.2% of surgeons would operate on asymptomatic spinal stenosis, and 18.2% would operate on silent spinal stenosis. Among those who would not operate, most (57.1%) advised patients on avoidance behavior and up to 9.5% prescribed neck collars. For ossification of the posterior longitudinal ligament (OPLL), anterior removal was most commonly performed for one-level disease (p <0.001), whereas laminoplasty was most commonly performed for two- to four-level disease (p =0.036). More surgeons considered laminectomy and fusion for multilevel OPLL. Most surgeons generally preferred to use a rigid neck collar for 6 weeks postoperatively (p <0.001). Conclusions: The pooled recommendations include prophylactic or early decompression surgery for patients with silent cervical spinal stenosis, particularly OPLL. Anterior decompression is primarily suggested for one- or two-level disease, whereas laminoplasty is preferred for multilevel disease.

Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management

Caroline Yik-fong Hung,Xin-yin Wu,Vincent Chi-ho Chung,Endy Chun-hung Tang,Justin Che-yuen Wu,Alexander Yuk-lun Lau 한국한의학연구원 2019 Integrative Medicine Research Vol.8 No.3

Background: Acupuncture has been using as an alternative non-pharmacological therapy in the management of post stroke depression and cognitive impairment but its effectiveness and safety remain controversial. We conducted an overview of systematic reviews with meta-analyses to evaluate the evidence on the effect of acupuncture in the treatment of stroke with conventional medicine intervention. Methods: Systematic reviews summarized the treatment effects of acupuncture for post stroke cognitive impairment and post stroke depression were considered eligible. Methodological quality of included systematic reviews was assessed using A MeaSurement Tool to Assess systematic Reviews 2 (AMSTAR 2). Results: Four systematic reviews on post stroke cognitive impairment and ten systematic reviews on post stroke depression with good methodological quality were included. Meta-analyses revealed that acupuncture plus cognitive rehabilitation; and acupuncture or moxibustion plus cognitive rehabilitation, versus cognitive rehabilitation demonstrated statistically significant increase in Mini-Mental State Examination scores in compared to cognitive rehabilitation after 4 weeks treatment [Pooled weighted mean difference (WMD) = 3.14, 95% confidence interval (CI) = 2.06 to 4.21, I2 = 36%]; and (Pooled WMD = 3.22, 95% CI = 2.09 to 4.34, I2 = 0%). Furthermore, acupuncture versus antidepressant demonstrated statistically significant improve depression measured by increasing in 17-item Hamilton Depression Rating Scale in comparing to cognitive rehabilitation after 2 weeks treatment (Pooled WMD= -2.34, 95% CI= -3.46 to -1.22, I2 = 5%). Acupuncture usage was not associated with increased risk of adverse events. Conclusions: Acupuncture is safe and improves cognitive function and depressive disorder without obvious serious adverse events for post stroke patients.

Treatment outcomes of patients with stage II pure endometrioid-type endometrial cancer: a Taiwanese Gynecologic Oncology Group (TGOG-2006) retrospective cohort study

Hung-Chun Fu,Jen-Ruei Chen,Min-Yu Chen,Keng-Fu Hsu,Wen-Fang Cheng,An Jen Chiang,Yu-Min Ke,Yu-Chieh Chen,Yin-Yi Chang,Chia-Yen Huang,Chieh-Yi Kang,Yuan-Yee Kan,Sheng-Mou Hsiao,Ming-Shyen Yen 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.5

Objective: Choice of hysterectomy and adjuvant treatment for International Federation of Gynecology and Obstetrics (FIGO) 2009 stage II endometrioid endometrial cancer (EEC) is still controversial. Aims of this study were to evaluate survival benefits and adverse effects of different hysterectomies with or without adjuvant radiotherapy (RT), and to identify prognostic factors. Methods: The patients at 14 member hospitals of the Taiwanese Gynecologic Oncology Group from 1992 to 2013 were retrospectively investigated. Patients were divided into simple hysterectomy (SH) alone, SH with RT, radical hysterectomy (RH) alone, and RH with RT groups. Endpoints were recurrence-free survival (RFS), overall survival (OS), disease-specific survival (DSS), adverse effects and prognostic factors for survival. Results: Total of 246 patients were enrolled. The 5-year RFS, OS, DSS and recurrence rates for the entire cohort were 89.5%, 94.3%, 96.2% and 10.2%, respectively. Patients receiving RH had more adverse effects including blood loss (p<0.001), recurrent urinary tract infections (p=0.013), and leg lymphedema (p=0.038). Age over 50-year (HR=9.2; 95% confidence interval [CI], 1.2–70.9) and grade 3 histology (HR=7.28; 95% CI, 1.45–36.6) were independent predictors of OS. Grade 3 histology was an independent predictor of RFS (HR=5.13; 95% CI, 1.38–19.1) and DSS (HR=5.97; 95% CI, 1.06–58.7). Patients receiving adjuvant RT had lower locoregional recurrence (p=0.046), but no impact on survival. Conclusion: Different treatment modalities yield similar survival outcomes. Patients receiving SH with RT had lower locoregional recurrent with acceptable morbidity. Age and tumor grading remained significant predictors for survival among patients with FIGO 2009 stage II EEC.

Iridoid Compounds from Boschniakia rossica

Yin, Zong Zhu,Kim, Hang Sub,Kim, Young Ho,Lee, Jung Joon 충남대학교 약학대학 의약품개발연구소 1999 藥學論文集 Vol.15 No.-

Four iridoid compounds were isolated from methanol extract of Boschniakia rossica by repeated column chromatography. Their structures were determined as boschnaloside (1), boschnarol (2), bosnarol methylether (3), and 7-deoxy 8-epiloganic acid (4), respectively. Compound 2, 3, and 4 were isolated for the first time from this plant.

Activation of Small GTPases RhoA and Rac1 Is Required for Avian Reovirus p10-induced Syncytium Formation

Hung-Jen Liu,Ping-Yuan Lin,Ling-Rung Wang,Hsue-Yin Hsu,Ming-Huei Liao,Wen-Ling Shih 한국분자세포생물학회 2008 Molecules and cells Vol.26 No.4

The first ORF of the ARV S1133 S1 segment encodes the nonstructural protein p10, which is responsible for the induction of cell syncytium formation. However, p10-dependent signaling during syncytium formation is fully unknown. Here, we show that dominant negative RhoA, Rho inhibitor C3 exoenzyme, ROCK/Rho-kinase inhibitor Y-27632 and Rac1 inhibitor NSC23766 inhibit p10-mediated cell fusion. p10 over-expression is concomitant with activation and membrane translocation of RhoA and Rac1, but not cdc42. RhoA and Rac1 downstream events, including JNK phosphorylation and transcription factor AP-1 and NF-B activation, as well as MLC expression and phosphorylation are simultaneously activated by p10. p10 point mutant T13M possessed 20% fusion-inducing ability and four p10 fusion-deficient mutants V15M, V19M, C21S and L32A reduced or lost their ability to activate RhoA and Rac1 signaling. We conclude that p10-mediated syncytium formation proceeds by utilizing RhoA and Rac1-dependent signaling.

Iridoid Compounds from Boschniakia rossica

Yin, Zong-Zhu,Kim, Hang-Sub,Kim, Young-Ho,Lee, Jung-Joon The Pharmaceutical Society of Korea 1999 Archives of Pharmacal Research Vol.22 No.1

Four iridoid compounds were isolated from methanol extract of Boschniakia rossica by repeated column chromatography. Their structures were determined as boschnaloside (1), boschnarol (2), bosnarol methylether (3), and 7-deoxy 8-epiloganic acid (4), respectively. Compound 2, 3, and 4 were isolated for the first time form this plant.

Rice-panicle-like γ-Fe₂O₃@C nanofibers as high-rate anodes for superior lithium-ion batteries

Yin, Linghong,Gao, Ying Jun,Jeon, Injun,Yang, Hang,Kim, Jong-Pil,Jeong, Se Young,Cho, Chae Ryong Elsevier 2019 CHEMICAL ENGINEERING JOURNAL -LAUSANNE- Vol.356 No.-

<P><B>Abstract</B></P> <P>We synthesized nanoarchitectures comprising γ-Fe<SUB>2</SUB>O<SUB>3</SUB>@C nanofibers with one-dimensional rice-panicle-like morphologies via a facile electrospinning and annealing process for use as anodes in lithium-ion batteries (LIBs). A thin carbon layer grown on the surface of γ-Fe<SUB>2</SUB>O<SUB>3</SUB> provides a synergistic effect to relieve the stress and alleviate the volume expansion occurring during the lithium-ion insertion/extraction process. The unique structure not only offers good electron transport routes, but also enhances the lithium-ion conductive channels, resulting in excellent electrochemical activity and electrical conductivity of the LIB anode material. A high reversible specific capacity of 1252 mAh g<SUP>−1</SUP> was achieved after 200 cycles even at the current density of 10 A g<SUP>−1</SUP>. When examined at the scan rate of 5 mV s<SUP>−1</SUP>, a high capacitive contribution ratio of 88.5% was achieved. The short lithium-ion diffusion pathways avoid structural damage to the active material and provide excellent rate capacities. This work suggests a new method to improve the electrochemical performance of LIBs through the synergistic design of uniquely structured metal oxides.</P> <P><B>Highlights</B></P> <P> <UL> <LI> 1D rice-panicle-like γ-Fe<SUB>2</SUB>O<SUB>3</SUB>@C nanofibers are successfully fabricated. </LI> <LI> Sufficient active sites for lithium storage are provided by unique structure. </LI> <LI> High rate capability of γ-Fe<SUB>2</SUB>O<SUB>3</SUB>@C electrode was achieved. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>One-dimensional γ-Fe<SUB>2</SUB>O<SUB>3</SUB>@C NFs with rice-panicle-like morphology was successfully fabricated via a facile electrospinning and post annealing process. A stable and high reversible specific capacity of 1252 mAh g<SUP>−1</SUP> was achieved after 200 cycles at a current density of 10 A g<SUP>−1</SUP>, which was ascribed to the synergistic effect of a novel combination between ultrathin carbon layer and γ-Fe<SUB>2</SUB>O<SUB>3</SUB> nanocrystallites.</P> <P>[DISPLAY OMISSION]</P>