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Medx Exercise가 요통 환자의 요추부 근력 강화에 미치는 영향
장예선,황룡,임순길 제주관광대학 1999 論文集 Vol.5 No.-
The purpose of this study is to identify effectiveness of MedX Exercise Machine being developed for reinforcing lumbar muscular strength of patients with lumbago through conducting 8 weeks of exercise by applying above-mentioned machine. Subjects of this study were a total of 30 people composed of a group of lumbago patients (15 persons) who had no operation and a group of lumbago patients (15 persons) who had operation subjected to MedX Exercise at U vertebra health research institute in Seoul. The tool of experiment was MedX Lumbar Extension Machine (MedX, Ocala, FL USA) and by means of this machine test was conducted by computing strength at tip of joint movement range with test angle between indentation of lumbar with no contraction of 72° - 0° (7 angles) standardized. In the course of extension test for lumbar with no contraction bar graph was produced by plotting muscular power of patients and secondary curves were produced by computer. The patients tested were subjected to an exercise program of 8 weeks with 3 times a week and 2 hours a session regime and the dates for exercise were fixed on Monday, Wednesday and Friday. Exercise was performed some time between 14:00 - 18:00 without fixed schedule. In general under the principle of therapy for curing paints Alpha Massage (johnson & johnson. USA) for treating heat on body surface was performed for 20 minutes thermally (36.7°C) prior to MedX Exercise and thereafter conducted light aerobic exercise for 45 minutes with 15 minutes session and carried out MedX Exercise for 30 minutes. As a winding up exercise cold therapy (18.3°C) was performed for 20 minutes. MedX Exercise for reinforcing lumbar muscular strength was conducted two 2 sets of 10-12 times with 15 minutes session and recorded that it improved muscular strength of the subject patients. In the course of conduction MedX Lumbar Extention Test the section of 0° - 72° was divided into 7 subsections (72°, 62°, 48°, 36°, 24°, 12°, 0°) and patients were made to generate maximum muscular strength for 2 seconds respectively. In the course of test for the purpose of strengthing lumbar muscular strength measurements were taken for 2 times in total before the exercise and after exercise for 8 weeks. Main results were 1. There was considerable increase in lumbar muscular strength because prior to starting exercise it was 796.5ft-lbs but after 8 weeks from exercise this figure was 1251.8ft-lbs (p<0.01). 2. It was shown that lumbago patients who had not operation (485.8ft-lbs) have higher level of improvement in muscular strength compared to lumbago patients who had operation (424.8ft-lbs). From the result mentioned above it was possible to draw a conclusion that by means of MedX Exercise considerable improvement of lumbar muscular strength is possible and therapeutic exercise substantiated by scientific method is effective and suitable to prevention and treatment of lumbago.
여수국가산업단지 인근 지역 대기오염물질 농도에 영향을 미치는 요인분석
김민영,변정훈,이영훈,이건영,한지은,이예림,임지현,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2
Eight monitoring stations in the Yeosu National Industrial Complex will determine the concentration of air pollutants measured every hour in 2019, analyze what factors affect them, and how they correlate with the air pollutant measurements. Six air pollutants (SO2, NO2, O3, CO, PM-10 and PM-2.5) measured at eight monitoring stations around Yeosu National Industrial Complex (Seogang-dong, Wolnae-dong, Munsu-dong, Yeocheon-dong, Deokchung-dong, Hwayang-myeon, Yulchon-myeon, Samil-dong) the measurement data for each hour of the year were downloaded to analyze the concentration by weather condition, time zone, season, separation distance from Yeosu Industrial Complex, and separation distance from Gwangyang Industrial Complex. SO2, NO2, and CO concentrations were significantly higher in winter, significantly lower in summer, and O3, PM-10, and PM-2.5 concentrations were significantly higher in spring. SO2, CO, PM-10, and PM-2.5 concentrations were significantly higher between 10 a.m. and 12 p.m., NO2 concentrations were significantly higher between 7 a.m. and 9 a.m., and O3 concentrations were significantly higher between 13 p.m. and 15 p.m.(p<0.001). The concentration of air pollutants (SO2, NO2, CO, PM-10, PM-2.5) excluding O3 was found to have a negative (-) correlation with weather condition, and in the case of O3, it was found to have a positive (+) correlation with PM-10, PM-2.5, temperature and wind speed. It was confirmed that the concentration of air pollutants emitted from the Yeosu National Industrial Complex differs depending on the season, time and distance to the industrial complex. This study aims to establish measures to minimize health damage to residents living relatively close to the industrial complex and contribute to the establishment of management and response measures according to the properties of substances to reduce the concentration of air pollutants in the future.
Jang, Ye-Lim,Kim, Sang-Gyu,Kim, Young-Ho The Korean Society of Plant Pathology 2011 Plant Pathology Journal Vol.27 No.4
Two antifungal bacteria were selected from forest soils during the screening of microorganisms antagonistic to Cylindrocarpon destructans, a cause of ginseng root rot. The antifungal bacteria were identified as Bacillus subtilis (I4) and B. amyloliquefaciens (yD16) based on physiological and cultural characteristics, the Biolog program, and 16S rRNA gene sequencing analyses. Antagonistic activity of both bacterial isolates to C. destructans increased with increasing temperature. More rapid starch hydrolytic activity of the bacteria was seen on starch agar at higher temperatures than at lower temperatures, and in the higher density inoculum treatment than in the lower density inoculum treatment. The bacterial isolates failed to colonize ginseng root the root tissues inoculated with the bacteria alone at an inoculum density of $1{\times}10^6$ cfu/ml, but succeeded in colonizing the root tissues co-inoculated with the bacteria and C. destructans. Scanning electron microscopy showed that the pathogen was damaged by the low-density inoculum treatment with the bacterial isolates as much as by the high-density inoculum treatment. Both bacterial isolates were more effective in reducing root rot when they were treated at a concentration of $1{\times}10^6$ cfu/ml than at $1{\times}10^8$ cfu/ml. Also, only the former treatment induced prominent wound periderm formation, related to structural defense against pathogen infection. The results suggest that the bacterial antagonists may have high potential as biocontrol agents against ginseng root rot at relatively low-inoculum concentrations.
Neuroprotective Effects of Cuscutae Semen in a Mouse Model of Parkinson's Disease
Ye, Minsook,Lee, Seul gi,Chung, Eun Sook,Lim, Su-jin,Kim, Won Seob,Yoon, Heera,Kim, Sun Kwang,Ahn, Kwang Sung,Jang, Young Pyo,Bae, Hyunsu Hindawi Publishing Corporation 2014 Evidence-based Complementary and Alternative Medic Vol.2014 No.-
<P>Parkinson's disease (PD) is a neurodegenerative movement disorder that is characterized by the progressive degeneration of the dopaminergic (DA) pathway. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) causes damage to the DA neurons, and 1-4-methyl-4-phenylpyridinium (MPP<SUP>+</SUP>) causes cell death in differentiated PC12 cells that is similar to the degeneration that occurs in PD. Moreover, MPTP treatment increases the activity of the brain's immune cells, reactive oxygen species- (ROS-) generating processes, and glutathione peroxidase. We recently reported that Cuscutae Semen (CS), a widely used traditional herbal medicine, increases cell viability in a yeast model of PD. In the present study, we examined the inhibitory effect of CS on the neurotoxicity of MPTP in mice and on the MPP+-induced cell death in differentiated PC12 cells. The MPTP-induced loss of nigral DA neurons was partly inhibited by CS-mediated decreases in ROS generation. The activation of microglia was slightly inhibited by CS, although this effect did not reach statistical significance. Furthermore, CS may reduce the MPP+ toxicity in PC12 cells by suppressing glutathione peroxidase activation. These results suggest that CS may be beneficial for the treatment of neurodegenerative diseases such as PD.</P>
Detection of an intermediate during the unfolding process of the dimeric ketosteroid isomerase
Jang, Do Soo,Lee, Hyeong Ju,Lee, Byeongdu,Hong, Bee Hak,Cha, Hyung Jin,Yoon, Jinhwan,Lim, Kwanseop,Yoon, Ye Jeong,Kim, Jehan,Ree, Moonhor,Lee, Hee Cheon,Choi, Kwan Yong Elsevier 2006 FEBS letters Vol.580 No.17
<P><B>Abstract</B></P><P>Failure to detect the intermediate in spite of its existence often leads to the conclusion that two-state transition in the unfolding process of the protein can be justified. In contrast to the previous equilibrium unfolding experiment fitted to a two-state model by circular dichroism and fluorescence spectroscopies, an equilibrium unfolding intermediate of a dimeric ketosteroid isomerase (KSI) could be detected by small angle X-ray scattering (SAXS) and analytical ultracentrifugation. The sizes of KSI were determined to be 18.7Å in 0M urea, 17.3Å in 5.2M urea, and 25.1Å in 7M urea by SAXS. The size of KSI in 5.2M urea was significantly decreased compared with those in 0M and 7M urea, suggesting the existence of a compact intermediate. Sedimentation velocity as obtained by ultracentrifugation confirmed that KSI in 5.2M urea is distinctly different from native and fully-unfolded forms. The sizes measured by pulse field gradient nuclear magnetic resonance (NMR) spectroscopy were consistent with those obtained by SAXS. Discrepancy of equilibrium unfolding studies between size measurement methods and optical spectroscopies might be due to the failure in detecting the intermediate by optical spectroscopic methods. Further characterization of the intermediate using <SUP>1</SUP>H NMR spectroscopy and Kratky plot supported the existence of a partially-folded form of KSI which is distinct from those of native and fully-unfolded KSIs. Taken together, our results suggest that the formation of a compact intermediate should precede the association of monomers prior to the dimerization process during the folding of KSI.</P>