Improved Quantum-Behaved Particle Swarm Method for Optimizing Complex Thin Plate Structure

Weitao Cheng,Yixiao Qin,Jinpeng Gu,Haibiao Gao,Yue Yan,Junle Yang,Yang Chen,Shen Su,Kaiyao Yang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.4

A large number of heavy-duty asymmetric thin-plate box girder structures exist in large equipment, and their optimization can reduce the amount of material used and increase their load-carrying capacity. A new optimization method based on the Improved Quantum-Behaved Particle Swarm Optimization method (IQBPSO) is proposed in order to efficiently solve the mathematical model for the rationalization and optimization design of structures. The penalty function and Lévy flight strategy are considered in the optimization design of the improved algorithm, thus transforming the constrained optimization problem into an unconstrained optimization problem and improving the diversity and local optimization search capability of the quantum particle swarm. A mathematical model for the optimal design of box girder section size is established with the reduction of beam cross-sectional area as the objective function and the thin plate strength, rigidity, and stability of the thin slab as the constraints. The rapid lightweight design of the thin plate box beam was achieved, resulting in a 9.6% reduction in the manufacturing cost of the thin plate box beam. The optimization results are compared with several solutions of the thin slab box beams to verify the reliability and validity of the proposed optimization method.

Fault injection and failure analysis on Xilinx 16 nm FinFET Ultrascale+ MPSoC

Weitao Yang,Yonghong Li,Chaohui He 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.6

Energetic particle strikes the device and induces data corruption in the configuration memory (CRAM),causing errors and even malfunctions in a system on chip (SoC). Software-based fault injection is aconvenient way to assess device performance. In this paper, dynamic partial reconfiguration (DPR) isadopted to make fault injection on a Xilinx 16 nm FinFET Ultrascaleþ MPSoC. And the reconfigurationmodule implements the Sobel and Gaussian image filtering, respectively. Fault injections are executed onthe static and reconfiguration modules' bitstreams, respectively. Another contribution is that the failuremodes and effects analysis (FMEA) method is applied to evaluate the system reliability, according to theobtained injection results. This paper proposes a software-based solution to estimate programmabledevice vulnerability.

System-on-Chip Single Event Effect hardening design and validation using proton irradiation

Yang Weitao,Li Yang,Guo Gang,He Chaohui,Wu Longsheng 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.3

A multi-layer design is applied to mitigate single event effect (SEE) in a 28 nm System-on-Chip (SoC). It depends on asymmetric multiprocessing (AMP), redundancy and system watchdog. Irradiation tests utilized 70 and 90 MeV proton beams to examine its performance through comparative analysis. Via examining SEEs in on-chip memory (OCM), compared with the trial without applying the multi-layer design, the test results demonstrate that the adopted multi-layer design can effectively mitigate SEEs in the SoC.

An Improvement of the Response Surface Method Based on Reference Points for Structural Reliability Analysis

Weitao Zhao,Weihua Liu,Qijiao Yang 대한토목학회 2016 KSCE Journal of Civil Engineering Vol.20 No.7

The Response Surface Method (RSM) is a powerful technique to evaluate the structural reliability. However, for a Limit State Function (LSF) with highly non-linear, the accuracy of the approximation of the failure probability does not depend very much upon the design point. It is necessary for RSMs to consider the design point and the non-linear trend of actual LSF around the design point, because both of them influence the failure probability. Thus, in order to improve the fitting precision of the Response Surface Function (RSF) to the actual LSF over a larger region containing the design point, the reference points of experimental points are constructed in this paper. Experimental points used to obtain parameters of a RSF are selected according to the information of reference points. Four examples are discussed in detail. The numerical results indicate that the accuracy and the efficiency of the proposed method are both desirable for both numerical and implicit LSFs, and the proposed method is superior to the classical RSM in terms of efficiency and accuracy.

An efficient response surface method considering the nonlinear trend of the actual limit state

Weitao Zhao,Zhiping Qiu,Yi Yang 국제구조공학회 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.47 No.1

In structural reliability analysis, the response surface method is a powerful method to evaluate the probability of failure. However, the location of experimental points used to form a response surface function must be selected in a judicious way. It is necessary for the highly nonlinear limit state functions to consider the design point and the nonlinear trend of the limit state, because both of them influence the probability of failure. In this paper, in order to approximate the actual limit state more accurately, experimental points are selected close to the design point and the actual limit state, and consider the nonlinear trend of the limit state. Linear, quadratic and cubic polynomials without mixed terms are utilized to approximate the actual limit state. The direct Monte Carlo simulation on the approximated limit state is carried out to determine the probability of failure. Four examples are given to demonstrate the efficiency and the accuracy of the proposed method for both numerical and implicit limit states.

An efficient response surface method considering the nonlinear trend of the actual limit state

Zhao, Weitao,Qiu, Zhiping,Yang, Yi Techno-Press 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.47 No.1

In structural reliability analysis, the response surface method is a powerful method to evaluate the probability of failure. However, the location of experimental points used to form a response surface function must be selected in a judicious way. It is necessary for the highly nonlinear limit state functions to consider the design point and the nonlinear trend of the limit state, because both of them influence the probability of failure. In this paper, in order to approximate the actual limit state more accurately, experimental points are selected close to the design point and the actual limit state, and consider the nonlinear trend of the limit state. Linear, quadratic and cubic polynomials without mixed terms are utilized to approximate the actual limit state. The direct Monte Carlo simulation on the approximated limit state is carried out to determine the probability of failure. Four examples are given to demonstrate the efficiency and the accuracy of the proposed method for both numerical and implicit limit states.

The Gut Microbiota of Pregnant Rats Alleviates Fetal Growth Restriction by Inhibiting the TLR9/MyD88 Pathway

Tang Hui,Li Hanmei,Li Dan,Peng Jing,Zhang Xian,Yang Weitao 한국미생물·생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.9

Fetal growth restriction (FGR) is a prevalent obstetric condition. This study aimed to investigate the role of Toll-like receptor 9 (TLR9) in regulating the inflammatory response and gut microbiota structure in FGR. An FGR animal model was established in rats, and ODN1668 and hydroxychloroquine (HCQ) were administered. Changes in gut microbiota structure were assessed using 16S rRNA sequencing, and fecal microbiota transplantation (FMT) was conducted. HTR-8/Svneo cells were treated with ODN1668 and HCQ to evaluate cell growth. Histopathological analysis was performed, and relative factor levels were measured. The results showed that FGR rats exhibited elevated levels of TLR9 and myeloid differentiating primary response gene 88 (MyD88). In vitro experiments demonstrated that TLR9 inhibited trophoblast cell proliferation and invasion. TLR9 upregulated lipopolysaccharide (LPS), LPS-binding protein (LBP), interleukin (IL)-1β and tumor necrosis factor (TNF)-α while downregulating IL-10. TLR9 activated the TARF3-TBK1-IRF3 signaling pathway. In vivo experiments showed HCQ reduced inflammation in FGR rats, and the relative cytokine expression followed a similar trend to that observed in vitro. TLR9 stimulated neutrophil activation. HCQ in FGR rats resulted in changes in the abundance of Eubacterium_coprostanoligenes_group at the family level and the abundance of Eubacterium_coprostanoligenes_group and Bacteroides at the genus level. TLR9 and associated inflammatory factors were correlated with Bacteroides, Prevotella, Streptococcus, and Prevotellaceae_Ga6A1_group. FMT from FGR rats interfered with the therapeutic effects of HCQ. In conclusion, our findings suggest that TLR9 regulates the inflammatory response and gut microbiota structure in FGR, providing new insights into the pathogenesis of FGR and suggesting potential therapeutic interventions.

A detector system for searching lost γ-ray source

Khan Waseem,He Chaohui,Cao Yu,Khan Rashid,Yang Weitao 한국원자력학회 2020 Nuclear Engineering and Technology Vol.52 No.7

The aim of this work is to develop a Geiger-Muller (GM) detector system for robot to look for a radioactive source in case of a nuclear emergency or in a high radiation environment. In order to find a radiation source easily, a detector system, including 3 detectors, was designed to search g-ray radiation sources autonomously. First, based on GEANT4 simulation, radiation dose rates in 3 Geiger-Muller (GM) counters were simulated at different source-detector distances, distances between detectors and angles. Various sensitivity analyses were performed experimentally to verify the simulated designed detector system. A mono-energetic 137Cs g-ray source with energy 662 keV and activity of 1.11 GBq was used for the observation. The simulated results were compared with the experimental dose rate values and good agreements were obtained for various cases. Only based on the dose rates in three detectors, the radiation source with a specific source activity and angle was localized in the different location. A method was adopted with the measured dose rates and differences of distances to find the actual location of the lost g-ray source. The corresponding angles of deviation and detection limits were calculated to determine the sensitivity and abilities of our designed detector system. The proposed system can be used to locate radiation sources in low and high radiation environments

A General Strategy for Construction of Both 2,6-cis- and 2,6-trans-Disubstituted Tetrahydropyrans: Substrate-Controlled Asymmetric Total Synthesis of (+)-Scanlonenyne

Lee, Hyunjoo,Kim, Kwan Woo,Park, Janghyun,Kim, Hyoungsu,Kim, Sanghee,Kim, Deukjoon,Hu, Xiangqian,Yang, Weitao,Hong, Jiyong WILEY-VCH Verlag 2008 Angewandte Chemie. international edition Vol.47 No.22

<B>Graphic Abstract</B> <P>A synthetic three-ring circus: The asymmetric total synthesis of (+)-scanlonenyne includes a sequential epimerization and intramolecular hetero-Michael addition for the construction of pyrano-γ-lactones (see scheme; DBU: 1,8-diazabicyclo[5.4.0]undec-7-ene), a highly efficient one-carbon homologation/bromination strategy, and a Weinreb ketone synthesis/cross-metathesis protocol for the elaboration of a sensitive side chain. <img src='wiley_img/14337851-2008-47-22-ANIE200705663-content.gif' alt='wiley_img/14337851-2008-47-22-ANIE200705663-content'> </P>

ChemInform Abstract: A General Strategy for Construction of Both 2,6-cis- and 2,6-trans-Disubstituted Tetrahydropyrans: Substrate-Controlled Asymmetric Total Synthesis of (+)-Scanlonenyne.

Lee, Hyunjoo,Kim, Kwan Woo,Park, Janghyun,Kim, Hyoungsu,Kim, Sanghee,Kim, Deukjoon,Hu, Xiangqian,Yang, Weitao,Hong, Jiyong WILEY-VCH Verlag 2008 Chem Inform Vol.39 No.37

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