Direct Chemical Vapor Deposition-Derived Graphene Glasses Targeting Wide Ranged Applications

Sun, Jingyu,Chen, Yubin,Priydarshi, Manish Kr.,Chen, Zhang,Bachmatiuk, Alicja,Zou, Zhiyu,Chen, Zhaolong,Song, Xiuju,Gao, Yanfeng,Rü,mmeli, Mark H.,Zhang, Yanfeng,Liu, Zhongfan American Chemical Society 2015 NANO LETTERS Vol.15 No.9

<P>Direct growth of graphene on traditional glasses is of great importance for various daily life applications. We report herein the catalyst-free atmospheric-pressure chemical vapor deposition approach to directly synthesizing large-area, uniform graphene films on solid glasses. The optical transparency and sheet resistance of such kinds of graphene glasses can be readily adjusted together with the experimentally tunable layer thickness of graphene. More significantly, these graphene glasses find a broad range of real applications by enabling the low-cost construction of heating devices, transparent electrodes, photocatalytic plates, and smart windows. With a practical scalability, the present work will stimulate various applications of transparent, electrically and thermally conductive graphene glasses in real-life scenarios.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2015/nalefd.2015.15.issue-9/acs.nanolett.5b01936/production/images/medium/nl-2015-019367_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl5b01936'>ACS Electronic Supporting Info</A></P>

Investigation on quasi-static and dynamic mechanical properties of disc springs considering asymmetric frictional boundary

Yanfeng Zhou,Dan Wang,Jianyuan He,Weifang Chen,Rupeng Zhu 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.11

Systematic experimental studies of disc springs are sparse. In this paper, quasistatic and dynamic compression experiments are performed on a single disc spring under both symmetric and asymmetric frictional conditions for different series of disc springs. On this basis, multiple disc springs stacked in parallel are also investigated. The full-range load-displacement curves of disc springs under quasi-static and dynamic compression are obtained and compared with the theoretical values, and the limitations of the existing analytical solutions are pointed out. The analysis revealed that frictional conditions of contact boundaries greatly affect the damping of disc springs. As the compression frequency increases, the damping of the disc spring gradually increases and finally remains stable. When the disc springs are stacked in parallel, the stiffness relationship can be approximated as conforming to the law of parallel connection, but the damping increases significantly due to the introduction of friction between internal contact surfaces.

Effect of polyethylene foam on dynamic cushioning energy absorption of paper corrugation tubes

Yanfeng Guo,Xuxiang Han,Yungang Fu,Shenghui Chen 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.4

The influence of the filled polyethylene foam on the cushioning energy absorption and impact resistance of the corrugation tube is analyzed through the axial drop impact experiment. Moreover, the compression deformation mode of the corrugation tube wall is predicted and experimentally verified. Results show that the X-direction tube has initial geometrical imperfections, which may reduce the initial impact force. The interaction between the polyethylene foam and the corrugation tube wall can improve the overall stability of the filled tube, and the structural stability of the double corrugation tube is the best. For the single tube, double tube, and single-filled tube, the volume (or mass) of the foam relative to the corrugation tube increases sequentially. The cushioning energy absorption of the paper corrugation tube is not improved, but the impact resistance is reinforced.

MiR-212 Attenuates MPP+-Induced Neuronal Damage by Targeting KLF4 in SH-SY5Y Cells

Yanfeng Song,Ying Liu,Xiaowei Chen 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.3

Purpose: Parkinson’s disease (PD) is a common age-dependent neurodegenerative disease. MiR-212 has been demonstrated toexert protective effects in several neurological disorders. The present study aimed to investigate the role and underlying molecularmechanism of miR-212 in PD. Materials and Methods: 1-methyl-4-phenylpyridinium (MPP+)-induced SH-SY5Y cells were applied as a PD model in vitro. RTqPCRwas used to measure the expression of miR-212 and Kruppel-like factor 4 (KLF4) mRNA. Western blot analysis was performedto detect the protein levels of KLF4, Notch1 and Jagged1. Cell viability and apoptosis were determined by the Cell CountingKit-8 and flow cytometry, respectively. Quantitative analysis of caspase-3 activity, lactate dehydrogenase (LDH), reactiveoxygen species (ROS), superoxide dismutase (SOD), tumor necrosis factor-α (TNF-α), and interleukin-1 beta (IL-1β) was conductedwith corresponding ELISA kits. Dual-luciferase reporter assay was employed to evaluate the relationship between miR-212 and KLF4. Results: MiR-212 was downregulated in MPP+-induced SH-SY5Y cells. Also, miR-212 alleviated MPP+-induced SH-SY5Y cell damage,embodied by increased cell viability, decreased caspase-3 activity, LDH release, ROS production, TNF-α, and IL-1β expression,as well as elevated SOD levels. KLF4 was a direct target of miR-212, and miR-212 repressed KLF4 expression in a post-transcriptionalmanner. Moreover, miR-212-mediated protection effects were abated following KLF4 expression restoration in MPP+-induced SH-SY5Y cells, represented as lowered cell viability and enhanced apoptotic rate. Furthermore, Notch signaling wasinvolved in the regulation of miR-212/KLF4 axis in MPP+-induced SH-SY5Y cells. Conclusion: miR-212 might attenuate MPP+-induced neuronal damage by regulating KLF4/Notch signaling pathway in SH-SY5Ycells, a promising target for PD therapy.

Combinatorial Methylerythritol Phosphate Pathway Engineering and Process Optimization for Increased Menaquinone-7 Synthesis in Bacillus subtilis

Taichi Chen,Hongzhi Xia,Shixiu Cui,Xueqin Lv,Xueliang Li,Yanfeng Liu,Jianghua Li,Guocheng Du,Long Liu 한국미생물·생명공학회 2020 Journal of microbiology and biotechnology Vol.30 No.5

Vitamin K2 (menaquinone) is an essential vitamin existing in the daily diet, and menaquinone-7 (MK- 7) is an important form of it. In a recent work, we engineered the synthesis modules of MK-7 in Bacillus subtilis, and the strain BS20 could produce 360 mg/l MK-7 in shake flasks, while the methylerythritol phosphate (MEP) pathway, which provides the precursor isopentenyl diphosphate for MK-7 synthesis, was not engineered. In this study, we overexpressed five genes of the MEP pathway in BS20 and finally obtained a strain (BS20DFHG) with MK-7 titer of 415 mg/l in shake flasks. Next, we optimized the fermentation process parameters (initial pH, temperature and aeration) in an 8-unit parallel bioreactor system consisting of 300-ml glass vessels. Based on this, we scaled up the MK-7 production by the strain BS20DFHG in a 50-l bioreactor, and the highest MK-7 titer reached 242 mg/l. Here, we show that the engineered strain BS20DFHG may be used for the industrial production of MK-7 in the future.

Patient preferences and shared decision making for the traditional Chinese medicine treatment of lung cancer: A discrete choice experiment study

Teng Yue,Wei Yan,Chen Yingyao,Yan Juntao,Liu Shimeng,Li Fuming,Bao Shiyi,Ren Yanfeng,Liu Liu,Yang Yi 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.3

Background: Traditional Chinese Medicine (TCM), integrating patient preferences into decision-making process, has been widely used in the multimodality therapy of lung cancer. This study aimed to estimate patient preferences for treatment and shared decision-making (SDM) modes concerning inpatient TCM treatment of lung cancer in Shanghai in order to provide a basis for clinical decision-making process on TCM therapy for lung cancer. Methods: This study was conducted among patients (n = 347) from nine tertiary hospitals in Shanghai by discrete-choice experiment (DCE) survey and Shared Decision-Making Questionnaire-patient version (SDM-Q-9) survey. The DCE was developed with the inclusion of the most relevant attributes at appropriate levels for the TCM treatment of lung cancer. The empirical data analyses of patients were performed using mixed logit models. Additionally, subgroup analysis was conducted. Results: In total, 347 respondents completed the questionnaire. All attributes’ coefficients were statistically significant for patients’ preferences. Patients showed strong preferences for increasing disease control rate, relieving nausea and vomiting, reducing the risk of side effects, and were concerned about monthly out-of-pocket costs. Subgroup analysis indicated that patients with a lower SDM-Q-9 score and those who were satisfied with medical services emphasized more importance of higher disease control rate. Furthermore, most of the patients (90.20%) self-reported a high willingness to use SDM during the decision-making process. Conclusion: In Shanghai, patients mainly preferred SDM and considered disease control rate as the most essential attribute in the TCM treatment of lung cancer. The study findings could underscore the importance of considering patients’ preferences and promote SDM.

The Research on Demands and Development Strategy of Mobile Travel Service--an Empirical Study based on Chinese Scenic spot

Miao Miao,Jinzhao Shi,Yanfeng Chen 보안공학연구지원센터 2014 International Journal of Multimedia and Ubiquitous Vol.9 No.7

Research and application of fluidized flotation units: A review

Jikang Han,Peng Chen,Taishan Liu,Yanfeng Li 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.126 No.-

Flotation cells have a wide range of applications in the field of particle separation as a traditional flotationunit. Due to the declining ore grades and the increasing market demand for mineral resources, recoveringparticles in a wider range of sizes efficiently is a challenge that plants must face, but which is not anadvantage of traditional units. The fluidized flotation cell is a new type of flotation unit that has emergedin the last 20 years and has been proven to have a good separation effect in a larger particle size range. Although studies related to fluidized bed flotation cells have been reported in the literature at this stage,the summary is not comprehensive enough to summarize the operating parameters and hydrodynamicproperties of cells. To fill this gap, this paper summarizes the unique structures and applications of fourfluidized bed flotation cells based on published research work. The factors affecting the operating parametersof cells have been extensively discussed. Progress related to the study of hydrodynamic parameters,such as minimum fluidization velocity, gas holdup, bed expansion and porosity in cells, is also reviewed. The end of the review offers some insights into future fluidized bed research interests.

Lifetime Enhancement of Aerospace Components Using a Dual Nitrogen Plasma Immersion Ion Implantation Process

Honghui Tong,Qinchuan Chen,LiLu Shen,Yanfeng Huo,Ke Wang,Tanmin Feng,Lilan Mu,Jun Zha,Paul K. Chu 한국진공학회(ASCT) 2002 Journal of Korean Vacuum Science & Technology Vol.6 No.2

Hydraulic pumps are used to control the landing wheels of aircrafts, and their proper operation is vital to plane safety. It is well known that adhesive wear failure is a major cause of pump failure. A dual nitrogen plasma immersion ion implantation process calling for the implantation of nitrogen at two different energies and doses has been developed to enhance the surface properties of the disks in the pumps. The procedures meet the strict temperature requirement of <200℃, and after the treatment, the working lifetime of the pumps increases by more than a factor of two. This experimental protocol has been adopted by the hydraulic pump factory as a standard manufacturing procedure.

Mechanical behaviour between adjacent cracks in CFRP plate reinforced RC slabs

Xin Yuan,Hongyu Bai,Chen Sun,Qinqing Li,Yanfeng Song 국제구조공학회 2022 Structural Engineering and Mechanics, An Int'l Jou Vol.84 No.3

This paper discussed and analyzed the interfacial stress distribution characteristic of adjacent cracks in Carbon Fiber Reinforced Polymer (CFRP) plate strengthened concrete slabs. One un-strengthened concrete test beam and four CFRP platestrengthened concrete test beams were designed to carry out four-point flexural tests. The test data shows that the interfacial shear stress between the interface of CFRP plate and concrete can effectively reduce the crack shrinkage of the tensile concrete and reduces the width of crack. The maximum main crack flexural height in pure bending section of the strengthened specimen is smaller than that of the un-strengthened specimen, the CFRP plate improves the rigidity of specimens without brittle failure. The average ultimate bearing capacity of the CFRP-strengthened specimens was increased by 64.3% compared to that without CFRP-strengthen. This indicites that CFRP enhancement measures can effectively improve the ultimate bearing capacity and delay the occurrence of debonding damage. Based on the derivation of mechanical analysis model, the calculation formula of interfacial shear stress between adjacent cracks is proposed. The distributions characteristics of interfacial shear stress between certain crack widths were given. In the intermediate cracking region of pure bending sections, the length of the interfacial softening near the mid-span cracking position gradually increases as the load increases. The CFRP-concrete interface debonding capacity with the larger adjacent crack spacing is lower than that with the smaller adjacent crack spacing. The theoretical calculation results of interfacial bonding shear stress between adjacent cracks have good agreement with the experimental results. The interfacial debonding failure between adjacent cracks in the intermediate cracking region was mainly caused by the root of the main crack. The larger the spacing between adjacent cracks exists, the easier the interfacial debonding failure occurs.