여대생의 먹방 시청과 생활 스트레스, 음식중독 증상에 대한 연구

김대희,김영서,박채연,백정희,윤예원,장정원,전혜린,차윤정,Jiang Han,양숙자 이화여자대학교간호학회 2020 이화간호학회지 Vol.- No.54

Purpose: This study aimed to know whether there is a comparison of food video watching, life stress, food addiction symptom for female college students. Methods: A quantitative research is used. A total of 162 people were performed with questionnaire which was conducted from September 16, 2019 to October 2, 2019. The study sample was female college students of one university in Seoul. This study used general characteristics, life stress tool, and food addiction symptoms tool as a research tool. In dependent T-test, ANOVA, and pearson’s correlation was used for this study. Result: The food video watching time and the food addiction symptoms showed a significant positive of correlation (r=.230, p=.003). Also, life stress and food addiction symptoms were significantly correlated (r=.329, p<.001). However, food video watching time and life stress did not show statistically significant correlation (r=.062, p=.430). Conclusion: Based on the study results, food video watching time and life stress are highly correlated with food addiction symptoms. The findings of this study could be the basis for later research on nursing intervention in the life stress and food addiction symptoms among female college students.

A Phase 3 Evaluation of Daclatasvir plus Asunaprevir in Treatment-Naive Patients with Chronic HCV Genotype 1b Infection

( L. Wei ),( F. Wang ),( M. Zhang ),( J. Jia ),( A.A. Yakovlev ),( W. Xie ),( E.Z. Burnevich ),( J. Niu ),( Y.J. Jung ),( X. Jiang ),( M. Xu ),( X. Chen ),( Q. Xie ),( J. Li ),( J. Hou ),( H. Tang ),( 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Background/Aims: Treatment-naive GT 1b-infected patients from mainland China, South Korea and Russia were assessed for SVR at follow-up week 12 (SVR12) after receiving daclatasvir (60 mg, QD) and asunaprevir (100 mg, BID) (DCV+ASV). Methods: Patients were randomized 3:1 to receive DCV+ASV (24 weeks; immediate treatment [IM]) or 12 weeks of placebo followed by DCV+ASV (24 weeks; placebo-deferred treatment [PD]). The primary endpoint was to evaluate SVR12 in the IM arm to the historical rate for peginterferon/ribavirin (70%). Secondary endpoints included overall safety and safety comparisons between the treatment arms during the first 12 weeks. Results: 207 patients were randomized to IM (n=155) or PD (n=52); Asian (86%), female (59%), IL28B CC genotype (68%) and median age 49 (range 18-73) years; cirrhosis (13%), HCV RNA ≥6x106 IU/mL (53%). SVR12 in the IM arm was 92% and broadly unaffected by most baseline factors assessed (Figure); SVR12 was higher in patients without (96%) baseline NS5A-L31M/V or Y93H polymorphisms. There were 6 virologic breakthroughs, 6 relapses and 1 detectable HCV RNA at end-of-treatment in the IM arm. Safety was mostly comparable between the two arms during the first 12 weeks. The most frequent adverse events (AEs; ≥5%) during DCV+ASV (24 weeks) treatment in both arms were aminotransferase, bilirubin and INR elevations, hypertension, fatigue and respiratory tract infections; the most frequent treatment-emergent grade 3/4 laboratory abnormalities were aminotransferase (≤4.5%) and hematologic, lipase and total bilirubin abnormalities (≤2%); one patient (IM) discontinued DCV+ASV for aminotransferase elevations, nausea and jaundice (all reversible); one patient PD) discontinued DCV+ASV for a fatal AE unrelated to treatment. Conclusions: These data demonstrate that DCV+ASV is a highly efficacious and well tolerated treatment for treatment-naive HCV GT 1b-infected patients. Those treated immediately with DCV+ASV achieved a 92% SVR12 rate which was unaffected by factors known to attenuate response to interferon.

Effects of Alfalfa Meal on Growth Performance and Gastrointestinal Tract Development of Growing Ducks

Jiang, J.F.,Song, X.M.,Huang, X.,Zhou, W.D.,Wu, J.L.,Zhu, Z.G.,Zheng, H.C.,Jiang, Y.Q. Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.10

A study was conducted to evaluate effects of alfalfa meal on growth performance and gastrointestinal tract development of growing layer ducks to provide evidence for application of alfalfa meal in the duck industry. Two hundred and fifty-six healthy Shaoxing 7-wk old growing layer ducks were selected and randomly allocated to 1 of 4 dietary treatments based on corn and soybean meal and containing 0, 3, 6, and 9% of alfalfa meal for 8 wks. Each treatment consisted of 4 replicates of 16 ducks each. Briefly, birds were raised in separate compartments, and each compartment consisted of three parts: indoor floor house, adjacent open area and a connecting water area. The results showed: i) Growing ducks fed alfalfa meal diet were not significantly different in average daily gain, feed intake and gain-to-feed ratio from those fed no alfalfa diet (p>0.05). ii) Alfalfa meal increased the ratio crop, gizzard to live weight, caecum to live weight, the caecum index of growing ducks (p<0.05). iii) Villus height in duodenum and jejunum of growing ducks increased significantly with the increase of alfalfa meal levels (p<0.05). Crypt depth in duodenum and jejunum of growing ducks decreased significantly with the increase of alfalfa meal levels (p<0.05). This experiment showed that feeding of alfalfa meal to growing layer ducks could improve gastrointestinal tract growth and small intestinal morphology without effect on performance. This experiment provides evidence that alfalfa meal is a very valuable feedstuff for growing layer ducks.

Evidence for Viscoelastic Effects in Surface Capillary Waves of Molten Polymer Films

Jiang, Zhang,Kim, Hyunjung,Jiao, X.,Lee, H.,Lee, Y.-J.,Byun, Y.,Song, S.,Eom, D.,Li, C.,Rafailovich, M. H.,Lurio, L. B.,Sinha, S. K. American Physical Society 2007 Physical Review Letters Vol.98 No.22

Transition-Metal-Free Synthesis of Substituted Pyridines via Ring Expansion of 2-Allyl-2H-azirines

Jiang, Y.,Park, C.-M.,Loh, T.-P. THE AMERICAN CHEMICAL SOCIETY 2014 ORGANIC LETTERS Vol.16 No.13

Chitosan-graft-polyethylenimine as a gene carrier

Jiang, H.L.,Kim, Y.K.,Arote, R.,Nah, J.W.,Cho, M.H.,Choi, Y.J.,Akaike, T.,Cho, C.S. Elsevier Science Publishers 2007 Journal of controlled release Vol.117 No.2

Chitosans have been proposed as biocompatible alternative cationic polymers that are suitable for non-viral delivery. However, the transfection efficiency of chitosan-DNA nanoparticles is still very low. To improve transfection efficiency, we prepared chitosan-graft-polyethylenimine (CHI-g-PEI) copolymer by an imine reaction between periodate-oxidized chitosan and polyethylenimine (PEI). The molecular weight and composition of the CHI-g-PEI copolymer were characterized, using multi-angle laser scattering (GPC-MALS) and <SUP>1</SUP>H nuclear magnetic resonance (<SUP>1</SUP>H NMR), respectively. The copolymer was complexed with plasmid DNA (pDNA) in various copolymer/DNA (N/P) charge ratios, and the complex was characterized. CHI-g-PEI showed good DNA binding ability and high protection of DNA from nuclease attack. Also, with an increase in charge ratio, the sizes of the CHI-g-PEI/DNA complex showed a tendency to decrease, whereas the zeta potential of the complex showed an increase. The CHI-g-PEI copolymer had low cytotoxicity, compared to PEI 25K from cytotoxicity assays. At high N/P ratios, the CHI-g-PEI/DNA complex showed higher transfection efficiency than PEI 25K in HeLa, 293T and HepG2 cell lines. Our results indicate that the CHI-g-PEI copolymer has potential as a gene carrier in vitro.

Creep damage and crack initiation in P92-BNi2 brazed joint

Jiang, W.,Zhang, W.,Zhang, G.,Luo, Y.,Zhang, Y.C.,Woo, W.,Tu, S.T. BUTTERWORTH - HEINEMANN 2015 MATERIALS AND DESIGN Vol.72 No.-

Nickel-based brazed joints are widely used at high temperatures, and it is very important to ensure the creep strength. Using three-dimensional finite element method, this paper presents a study on the creep damage and creep crack initiation (CCI) in P92-BNi2 brazed compact tension (CT) joint specimen, and the effect of brazed residual stress on CCI has been investigated. Firstly, the as-brazed residual stress is simulated. Then the effect of residual stress on creep and damage is calculated by an uncoupled Norton equation and the ductility exhaustion approach. The results show that the CCI is a function of residual stress, load level, joint thickness and notch radius. The brazed residual stress has a great effect on creep damage, and it can lead to the initiation of creep crack lonely without any mechanical load. The combination of applied load not only accelerates the creep damage and decreases the CCI time, but also determines the creep crack propagation rate. The CCI time decreases with the increase of applied load and joint thickness. As the notch radius increases, the CCI time increases.

Galactosylated chitosan-graft-polyethylenimine as a gene carrier for hepatocyte targeting

Jiang, H-L,Kwon, J-T,Kim, Y-K,Kim, E-M,Arote, R,Jeong, H-J,Nah, J-W,Choi, Y-J,Akaike, T,Cho, M-H,Cho, C-S Nature Publishing Group 2007 Gene Therapy Vol.14 No.19

Chitosans have been proposed as alternative, biocompatible cationic polymers for nonviral gene delivery. However, the low transfection efficiency and low specificity of chitosan need to be addressed before clinical application. We prepared galactosylated chitosan-graft-polyethylenimine (GC-g-PEI) copolymer by an imine reaction between periodate-oxidized GC and low-molecular-weight PEI. The molecular weight and composition were characterized using gel permeation chromatography column with multi-angle laser scattering and <SUP>1</SUP>H nuclear magnetic resonance, respectively. The copolymer was complexed with plasmid DNA in various copolymer/DNA (N/P) charge ratios, and the complexes were characterized. GC-g-PEI showed good DNA-binding ability and superior protection of DNA from nuclease attack and had low cytotoxicity compared to PEI 25K. GC-g-PEI/DNA complexes showed higher transfection efficiency than PEI 25K in both HepG2 and HeLa cell lines. Transfection efficiency into HepG2, which has asialoglycoprotein receptors, was higher than that into HeLa, which does not. GC-g-PEI/DNA complexes also transfected liver cells in vivo after intraperitoneal (i.p.) administration more effectively than PEI 25K. These results suggest that GC-g-PEI can be used in gene therapy to improve transfection efficiency and hepatocyte specificity in vitro and in vivo.Gene Therapy (2007) 14, 1389–1398; doi:10.1038/sj.gt.3302997; published online 19 July 2007

Identification of Differentially Expressed Proteins in Liver in Response to Subacute Ruminal Acidosis (SARA) Induced by High-concentrate Diet

Jiang, X.Y.,Ni, Y.D.,Zhang, S.K.,Zhang, Y.S.,Shen, X.Z. Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.8

The aim of this study was to evaluate protein expression patterns of liver in response to subacute ruminal acidosis (SARA) induced by high-concentrate diet. Sixteen healthy mid-lactating goats were randomly divided into 2 groups and fed either a high-forage (HF) diet or a high-concentrate (HC) diet. The HC diet was expected to induce SARA. After ensuring the occurrence of SARA, liver samples were collected. Proteome analysis with differential in gel electrophoresis technology revealed that, 15 proteins were significantly modulated in liver in a comparison between HF and HC-fed goats. These proteins were found mainly associated with metabolism and energy transfer after identified by matrix-assisted laser desorption ionization/time of flight. The results indicated that glucose, lipid and protein catabolism could be enhanced when SARA occurred. It prompted that glucose, lipid and amine acid in the liver mainly participated in oxidation and energy supply when SARA occurred, which possibly consumed more precursors involved in milk protein and milk fat synthesis. These results suggest new candidate proteins that may contribute to a better understanding of the mechanisms that mediate liver adaptation to SARA.

Use of negative capacitance to simulate the electrical characteristics in double-gate ferroelectric field-effect transistors

Y.G. Xiao,M.H. Tang,Y. Xiong,J. C. Lin,C.P. Cheng,B. Jiang,H.Q. Cai,Z.H. Tang,X.S. Lv,X.C. Gu,Y.C. Zhou 한국물리학회 2012 Current Applied Physics Vol.12 No.6

The surface potential and drain current of double-gate metal-ferroelectric-insulator-semiconductor (MFIS) field-effect transistor were investigated by using the ferroelectric negative capacitance. The derived results demonstrated that the up-converted semiconductor surface potential and low subthreshold swing S = 34 (<60 mV/dec) can be realized with appropriate thicknesses of ferroelectric thin film and insulator layer at room temperature. What’s more, a reduction gate voltage about 260 mV can be reached if the ON-state current is fixed to 600 mA/mm. It is expected that the derived results can offer useful guidelines for the application of low power dissipation in ongoing scaling of FETs.