The Lightweight Ownership Transfer Protocol using Physically Unclonable Function

Xuejun Zhang,Wanlu Huang,He Xu,Yu Wang 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.2

RFID technology has increasingly used in the various fields of our lives, and in the entire life cycle of the tag, there may be several ownership changes. Therefore, it is very important to protect the security and privacy of customer’s information during transferring. Combining with the physical characteristics of the anti-clone tag and the low-cost requirement, we proposed a lightweight ownership transfer protocol using Physically Unclonable Function (PUF) to achieve a safe ownership transfer. Through using formal analysis, it shows that this protocol can also resist reply attack, desynchronization attack, tampering attack, to protect the old and the new owner’s private information.

Enlarging the Terminal Region of Quasi-infinite Horizon NMPC Based on T-S Fuzzy Model

Shuyou Yu,Hong Chen,Xuejun Li 제어·로봇·시스템학회 2009 International Journal of Control, Automation, and Vol.7 No.3

The paper presents a method for enlarging the terminal region of quasi-infinity horizon nonlinear model predictive control (NMPC) for nonlinear systems with constraints. The main technique builds on the fact that terminal controllers are fictitious and never applied to the system in the quasi-infinite horizon NMPC [1]. Based on T-S fuzzy models of nonlinear systems, we show that a parameter-dependent state feedback law exists such that the corresponding value function and its level set can be served as terminal cost and terminal region. The problem of maximizing the terminal region is formulated as a convex optimization problem based on linear matrix inequalities (LMIs). A numerical example is given to illustrate the effectiveness of the proposed method.

Mechanical Properties and Microstructure of Lime-Treated Red Clay

Lijie Chen,Xuejun Chen,He Wang,Xiang Huang,Yu Song 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.1

This research conducted a triaxial test on lime-treated clay with different contents to analyze the effect of mechanical properties. Scanning electron microscope (SEM) and low-field nuclear magnetic resonance (NMR) analysis were used to analyze the effect. X-ray diffraction (XRD) was used to analyze the chemical changes of calcium oxide on red clay. The results show that with the increase of calcium oxide content, the strength increases, and it can be increased by 282% at 200 kPa confining pressure. The calcium oxide in the red clay reactedwith the water in the soil to form calcium hydroxide. The alkaline environment will erode the edge of the soil particles and cause pores to become larger. SEM observed that the addition of calcium oxide caused the agglomeration of soil particles and changed the pore structure of red clay. Low-field NMR showed that calcium oxide had a significant effect on the pore structure of red clay. Calcium oxide increased the total pore volume of the soil sample. Calcium oxide had a substantial influence on the three pore distribution ranges, I (1.1 − 11 μm), II (15 − 137 μm), and III (137 − 512 μm). The porosity fitted with shear strength, it negatively correlated with I and III, and positively correlated with II.

Ginsenoside Rh2 reduces depression in offspring of mice with maternal toxoplasma infection during pregnancy by inhibiting microglial activation via the HMGB1/TLR4/NF-kB signaling pathway

Xiang Xu,Yu-Nan Lu,Jia-Hui Cheng,Hui-Wen Lan,Jing-Mei Lu,Guang-Nan Jin,Guang-Hua Xu,Cheng-Hua Jin,Juan Ma,Hu-Nan Piao,Xuejun Jin,Lian-Xun Piao 고려인삼학회 2022 Journal of Ginseng Research Vol.46 No.1

Background: Maternal Toxoplasma gondii (T. gondii) infection during pregnancy has been associated with various mental illnesses in the offspring. Ginsenoside Rh2 (GRh2) is a major bioactive compound obtained from ginseng that has an anti-T. gondii effect and attenuates microglial activation through toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-kB) signaling pathway. GRh2 also alleviated tumor-associated or lipopolysaccharide-induced depression. However, the effects and potential mechanisms of GRh2 on depression-like behavior in mouse offspring caused by maternal T. gondii infection during pregnancy have not been investigated. Methods: We examined GRh2 effects on the depression-like behavior in mouse offspring, caused by maternal T. gondii infection during pregnancy, by measuring depression-like behaviors and assaying parameters at the neuronal and molecular level. Results: We showed that GRh2 significantly improved behavioral measures: sucrose consumption, forced swim time and tail suspended immobility time of their offspring. These corresponded with increased tissue concentrations of 5-hydroxytryptamine and dopamine, and attenuated indoleamine 2,3-dioxygenase or enhanced tyrosine hydroxylase expression in the prefrontal cortex. GRh2 ameliorated neuronal damage in the prefrontal cortex. Molecular docking results revealed that GRh2 binds strongly to both TLR4 and high mobility group box 1 (HMGB1). Conclusion: This study demonstrated that GRh2 ameliorated the depression-like behavior in mouse offspring of maternal T. gondii infection during pregnancy by attenuating the excessive activation of microglia and neuroinflammation through the HMGB1/TLR4/NF-kB signaling pathway. It suggests that GRh2 could be considered a potential therapy in preventing and treating psychiatric disorders in the offspring mice of mothers with prenatal exposure to T. gondii infection.

A Design of the Evaluation and Prediction of Power Energy Consumption of Office Buildings based on Multivariate Linear Regression

Nie Zihang,Xuejun Yu 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.4

In recent years, with the rapid increase of office buildings and the requirements to improve the office environment, office building energy consumption has increased significantly. That has brought great pressure to the user, environment and city power supply and demand. The electric energy consumption of office building conservation is the most important way to reduce the energy consumption. Simulation is a major method to understand about office building power consumption. At present domestic and foreign computer software simulation technology cannot work without a lot of professional parameters. And the obtained results is so professional that cannot give the management decision auxiliary. This paper presents a holistic statistical distribution instead of complex thermodynamic iterative computation model, and the analysis method. Using the mode "facing to the whole" for analysis of power energy consumption of office buildings, without more intricate parameters, and can be iterative adjusted according to the difference between measured data and the prediction.

Resources, production and management for edible matsutake in China

Zhong Chonglu,Gong Mingqin,Chen Yu,Wang Fengzhen,Li Chun,Huang Haikui,Chen Xuejun 한국버섯학회 2004 한국버섯학회 국제학술대회 Vol.3 No.-

The hydrogen storage nanomaterial MgH2 improves irradiation-induced male fertility impairment by suppressing oxidative stress

Jing Ma,Suhe Dong,Hongtao Lu,Zhongmin Chen,Huijie Yu,Xuejun Sun,Renjun Peng,Wei Li,Sinian Wang,Qisheng Jiang,Fengsheng Li,Li Ma 한국생체재료학회 2022 생체재료학회지 Vol.26 No.2

Objective: This study aimed to reveal the protective effect of hydrogen storage nanomaterial MgH2 on radiationinduced male fertility impairment. Methods: The characterization of MgH2 were analyzed by scanning electron microscopy (SEM) and particle size analyzer. The safety of MgH2 were evaluated in vivo and in vitro. The radioprotective effect of MgH2 on the reproductive system were analyzed in mice, including sperm quality, genetic effect, spermatogenesis, and hormone secretion. ESR, flow cytometry and western blotting assay were used to reveal the underlying mechanisms. Results: MgH2 had an irregular spherical morphology and a particle size of approximately 463.2 nm, and the content of Mg reached 71.46%. MgH2 was safe and nontoxic in mice and cells. After irradiation, MgH2 treatment significantly protected testicular structure, increased sperm density, improved sperm motility, reduced deformity rates, and reduced the genetic toxicity. Particularly, the sperm motility were consistent with those in MH mice and human semen samples. Furthermore, MgH2 treatment could maintain hormone secretion and testicular spermatogenesis, especially the generation of Sertoli cells, spermatogonia and round sperm cells. In vitro, MgH2 eliminated the [·OH], suppressed the irradiation-induced increase in ROS production, and effectively alleviated the increase in MDA contents. Moreover, MgH2 significantly ameliorated apoptosis in testes and cells and reversed the G2/M phase cell cycle arrest induced by irradiation. In addition, MgH2 inhibited the activation of radiation-induced inflammation and pyroptosis. Conclusion: MgH2 improved irradiation-induced male fertility impairment by eliminating hydroxyl free radicals.

Engineering tumor-specific catalytic nanosystem for NIR-II photothermal-augmented and synergistic starvation/chemodynamic nanotherapy

Shuixiu Zhou,Jiahuan Xu,Yanfei Dai,Yan Wei,Liang Chen,Wei Feng,Yu Chen,Xuejun Ni 한국생체재료학회 2022 생체재료학회지 Vol.26 No.4

Background: As an emerging therapeutic modality, chemodynamic therapy (CDT), converting hydrogen peroxide (H2O2) into highly toxic reactive oxygen species (ROS), has been developed for tumor-specific therapy. However, the deficiency of endogenous H2O2 and high concentration of glutathione (GSH) in the tumor microenvironment (TME) weaken the CDT-based tumor-therapeutic efficacy. Herein, a photothermal-enhanced tumor-specific cascade catalytic nanosystem has been constructed on the basis of glucose oxidase (GOD)-functionalized molybdenum (Mo)-based polyoxometalate (POM) nanoclusters, termed as GOD@POMs. Methods: GOD@POMs were synthesized by a facile one-pot procedure and covalently conjugation. Then, its structure was characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS). In addition, ultraviolet-visiblenear-infrared (UV-vis-NIR) absorption spectrum and infrared thermal camera were applied to evaluate the catalytic and photothermal performance, respectively. Moreover, to confirm the therapeutic effects in vitro, cell counting kit-8 (CCK-8) assay, live/dead staining and ROS staining were performed. Furthermore, the biosafety of GOD@POMs was investigated via blood routine, blood biochemistry and hematoxylin and eosin (H&E) staining in Kunming mice. Besides, the C6 glioma tumor-bearing mice were constructed to evaluate its anti-tumor effects in vivo and its photoacoustic (PA) imaging capability. Notably, RNA sequencing, H&E, TdT-mediated dUTP nick end labeling (TUNEL) and Ki-67 staining were also conducted to disclose its underlying anti-tumor mechanism. Results: In this multifunctional nanosystem, GOD can effectively catalyze the oxidation of intratumoral glucose into gluconic acid and H2O2, achieving the cancer starvation therapy. Meanwhile, the generated gluconic acid decreases the pH in TME resulting in POM aggregation, which enables PA imaging-guided tumor-specific photothermal therapy (PTT), especially in the second near-infrared (NIR-II) biological window. Importantly, the Mo (VI) sites on POM can be reduced to Mo (V) active sites in accompany with GSH depletion, and then the post-produced Mo (V) transforms in situ overproduced H2O2 into singlet oxygen (1O2) via Russell mechanism, achieving self-enhanced CDT. Moreover, the PTT-triggered local tumor temperature elevation augments the synergistic nanocatalytic-therapeutic efficacy. Conclusions: Consequently, the integration of GOD-induced starvation therapy, H2O2 self-supply/GSH-depletion enhanced Mo-based CDT, and POM aggregation-mediated PTT endow the GOD@POMs with remarkable synergistic anticancer outcomes with neglectable adverse effects.