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      • Tunable magnetic properties of double perovskite La<sub>2</sub>Fe<sub>2-x</sub>Co<sub>x</sub>O<sub>6</sub>

        Wang, Weihua,Feng, Wuwei,Yuan, Jiangyan,Pang, Ning,Zhao, Xiaoxue,Li, Meiyun,Bao, Zhidi,Zhu, Kun,Odkhuu, Dorj Elsevier 2018 PHYSICA B-CONDENSED MATTER - Vol.540 No.-

        <P><B>Abstract</B></P> <P>Double perovskite La<SUB>2</SUB>Fe<SUB>2-x</SUB>Co<SUB>x</SUB>O<SUB>6</SUB> was prepared and studied. Orthorhombic and trigonal structures were obtained depend on the molar ratio of Fe to Co. Fe-rich sample demonstrate ferrimagnetic properties; with increasing content of Co, trigonal structure is favored and the net magnetic moment of sample decrease gradually to zero. Our experimental results were further supported by first-principle theoretical calculations and demonstrate that La<SUB>2</SUB>Fe<SUB>2-x</SUB>Co<SUB>x</SUB>O<SUB>6</SUB> is a new high <I>T</I> <SUB> <I>c</I> </SUB> ferromagnetic semiconductor with tunable magnetic properties and is thus a promising material for spintronics devices.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Phase-pure double perovskite La2Fe2-xCoxO6 was prepared. </LI> <LI> Orthorhombic and trigonal structures were obtained depending on the ratio of Fe to Co. </LI> <LI> La2Fe2-xCoxO6 is a new high Tc ferromagnetic semiconductor with tunable magnetic properties. </LI> <LI> Theoretical ab initio calculations further support our experimental results. </LI> </UL> </P>

      • KCI등재

        High expression of HOXC6 predicts a poor prognosis and induces proliferation and inflammation in multiple myeloma cells

        Li Zhihua,Wang Yaru,Hou Xiaoxu,Guo Luyao,Li Yanling,Ma Yanping,Ma Yanping 한국유전학회 2023 Genes & Genomics Vol.45 No.7

        Background Multiple myeloma (MM) is a common blood system malignance accompanied by monoclonal plasma cell hyperplasia. Homeobox C6 (HOXC6) acts as an oncogene in various cancers, but its function on MM is elusive. Objective The role of HOXC6 on MM development was clarified in this study. Methods HOXC6 expression and its clinical significance were determined in the peripheral blood samples collected from forty MM patients and thirty healthy adult volunteers. The overall survival was evaluated by Kaplan-Meier analysis with the log-rank test. Cell viability, proliferation and apoptosis were measured by CCK-8, EdU assay and Flow cytometry in U266 and MM.1R cells. Tumor growth was estimated by a xenograft assay. The apoptosis of tumor tissues was evaluated using TUNEL staining. The protein level in tissues was tested by immunohistochemistry. Results The HOXC6 expression was elevated in MM and high HOXC6 level was associated with the poor overall survival of MM. Besides, the HOXC6 expression was associated with hemoglobin level and ISS stage. Furthermore, silencing HOXC6 suppressed cell proliferation, induced cell apoptosis, and restrained the secretion of inflammatory factors (TNF-α, IL-6, and IL-8) in MM cells through inactivating the NF-κB pathway. Moreover, silencing HOXC6 suppressed the tumor growth of MM, the inflammatory factors levels, and the activation of NF-κB pathway but enhanced apoptosis in vivo. Conclusion HOXC6 was elevated in MM and associated with poor survival. Knockdown of HOXC6 suppressed proliferation, inflammation and tumorigenicity of MM cells via inactivating the NF-κB pathway. HOXC6 may be a meaningful target for MM therapy.

      • SCIESCOPUSKCI등재

        Partial discharge detection of insulated conductors based on CNN-LSTM of attention mechanisms

        Li, Zhongzhi,Qu, Na,Li, Xiaoxue,Zuo, Jiankai,Yin, Yanzhen The Korean Institute of Power Electronics 2021 JOURNAL OF POWER ELECTRONICS Vol.21 No.7

        Under the condition of a strong electric field, partial discharge often occurs when insulated wire is damaged. The recognition of partial discharge is an effective method for the fast and accurate detection of high voltage insulated wire faults. This paper proposes a PD recognition algorithm based on a convolutional neural network and long short-term memory (LSTM). In addition, attention mechanisms are introduced to give separate weights to LSTM hidden states through a mapping, weighting, and learning parameter matrix. This is done to reduce the loss of historical information and to strengthen the influence of important information. The complex relationship between the voltage signal change and the grid operation state response has been established. The proposed method is verified by the ENET data set published by VSB University. The recognition accuracy is 95.16% for no-PD and 94.44% for PD. Results from the proposed algorithm show that this method has a higher detection accuracy.

      • Application of Improved Grid Search Algorithm on SVM for Classification of Tumor Gene

        Li Wenwen,Xing Xiaoxue,Liu Fu,Zhang Yu 보안공학연구지원센터 2014 International Journal of Multimedia and Ubiquitous Vol.9 No.11

        According to the merits and shortcomings of the traditional gridsearch algorithm in parameters optimization of support vector machine (SVM), an improved grid search algorithm is proposed. Dichotomous search algorithm is used to reduce target searching range. First, searching range is determined roughly, and a set of parameters are obtained. Then fine search is applied in reduction the range for searching, and searching the optimum parameters.Three kinds of famous tumor gene data set are used in the comparison experiments to validate the classification accuracy of principal component analysis (PCA)-SVM and kernel principal component analysis (KPCA)-SVM. Experiment results and data analysis shows that, comparing with traditional gridsearch algorithm, the proposed method has higher classification accuracy and less search time.

      • KCI등재

        Accumulation of Flavonoids and Antioxidant Activity of Stellera chamaejasme by an Efficient Callus Culture

        Jun-li Wang,Xuan Xiao,Qian Wang,Xiaoxu Li,Lu Zhang,Jianfei Li 한국원예학회 2013 Horticulture, Environment, and Biotechnology Vol.54 No.5

        An efficient callus proliferation system of Stellera chamaejasme was developed. The calli were initially induced by cultivating the leaf explants on the MS medium containing 1.0 mg·L-1 2,4-dichlorophenoxy acetic acid (2,4-D). The culture had its fresh and dry weights increased by about 29 and 25 times, respectively, through further cultivation on the MS medium containing 0.5 mg·L-1 α-naphthalene acetic acid (NAA) and 1.0 mg·L-1 n-phenyl-n′-1,2,3-thiadiazol-5-ylurea (TDZ). The concentrations of NAA and 6-benzylaminopurine (BA) for an efficient accumulation of the total flavonoids in the callus were found to be 1.0 mg·L-1 and 0.25 mg·L-1, respectively. With this combination,the content of the total flavonoids slightly increased to 10.8 mg·g-1 dry weight (DW) in comparison to 10.1 mg·g-1DW obtained in the root of wild-type plant. The antioxidant activities of all flavonoid extracts were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The flavonoid extracts from the callus as induced by 1.0 mg·L-1 NAA and 0.25 or 0.5 mg·L-1 BA was very active in radical scavenging, and their IC50 values were 11.94 and 19.17 μg·mL-1,respectively. Compared to the ascorbic acid (IC50 21.21 μg·mL-1), the antioxidant activity of callus from S. chamaejasme was even stronger, suggesting that be another potential source of new natural antioxidants.

      • KCI등재

        Multiple Gene Genealogical Analyses of a Nematophagous Fungus Paecilomyces lilacinus from China

        Juan Li,Heng Li,Xiaoxu Bi,Ke-Qin Zhang 한국미생물학회 2013 The journal of microbiology Vol.51 No.4

        Paecilomyces lilacinus is a geographically widespread nematophagous fungus and a promising biological control agent against plant parasitic nematodes. However, relatively little is known about its patterns of genetic variation through its broad geographic and ecological contexts. In this study, we analyzed the genetic variation of 2 virulence-associated genes (PLS and PLC) and 4 housekeeping gene fragments (ITS,RPB1, RPB2, and β-tubulin) among 80 P. lilacinus specimens collected from 7 locations in China. Various degrees of polymorphism and haplotype diversity were observed among the six gene fragments. However, no genetic differentiation was observed among the geographic populations, consistent with extensive gene flow among these geographic populations of P. lilacinus in China. Our analysis also suggested that clonal reproduction was the predominant mode of reproduction in natural populations of P. lilacinus.

      • KCI등재

        High vis-light photocatalytic property of g-C3N4 on four pollutants (RhB, MB, TC-HCl and P-Nitrophenol)

        Lian Xiaoxue,Li Yan,Zou Yunling,An Dongmin,Wang Qiong,Zhou Qingjun,Li Xueqi 한국물리학회 2022 Current Applied Physics Vol.39 No.-

        The g-C3N4 nanosheets were synthesized by a multistage program calcination with different heating rate, which was an easy, low-cost, and quick method. The morphology and structure of samples were characterized by various techniques. The performance evaluation of the samples was tested by degrading Rhodamine B, Methylene Blue, Tetracycline Hydrochloride and P-Nitrophenol in visible light. The results show that the photodegradation properties of TP-g-C3N4 prepared by multistage program calcination are the best than others. In particular, the degradation rate of TP-g-C3N4 to Rhodamine B reached 99.6% in just 4 min. TP-g-C3N4 catalyst has excellent stability and recycling performance. According to free radical capture experiments, •O2- may be the main active species for pollutant degradation. The possible photocatalytic degradation mechanism was also discussed. Due to the high specific surface area and a narrow band gap, the TP-g-C3N4 becomes a promising photocatalyst.

      • KCI등재

        Effect of Diammonium Phosphate Supplementation on the Amino Acid Metabolism during Fermentation and Sensory Properties of Fresh Spine Grape (Vitis davidii Foex) Wine

        Qing Jin,Liang Chen,Zheng Li,Xiaoxue Li,Jingming Li 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.6

        Spine grapes (Vitis daviddi Foex) are cultivated in southern China and possess a unique taste and flavor. However, nitrogen-deficiency results in poor quality spine wine. Diammonium phosphate (DAP) was added to spine grape must to determine the effect of DAP supplementation on the evolution of amino acids and associated by-products. DAP addition increased concentrations of amino acids from 73.5 to 101.0mg/L and biogenic amines from 3.9 to 5.0mg/L, but decreased concentrations of higher alcohols from 322.3 to 273.8mg/L and ethyl carbamate from 16.0 to 10.2 μg/L after fermentation. Sensory evaluation revealed that DAP supplementation kept the unique aroma and taste of fresh spine wine. DAP supplementation can benefit spine grape vinification and improve the quality of fresh spine wine.

      • KCI등재

        A Lightweight Pseudonym Authentication and Key Agreement Protocol for Multi-medical Server Architecture in TMIS

        ( Xiaoxue Liu ),( Yanping Li ),( Juan Qu ),( Yong Ding ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.2

        Telecare Medical Information System (TMIS) helps the patients to gain the health monitoring information at home and access medical services over the mobile Internet. In 2015, Das et al proposed a secure and robust user AKA scheme for hierarchical multi-medical server environment in TMIS, referred to as DAKA protocol, and claimed that their protocol is against all possible attacks. In this paper, we first analyze and show DAKA protocol is vulnerable to internal attacks, impersonation attacks and stolen smart card attack. Furthermore, DAKA protocol also cannot provide confidentiality. We then propose a lightweight pseudonym AKA protocol for multi-medical server architecture in TMIS (short for PAKA). Our PAKA protocol not only keeps good security features declared by DAKA protocol, but also truly provides patient`s anonymity by using pseudonym to protect sensitive information from illegal interception. Besides, our PAKA protocol can realize authentication and key agreement with energy-saving, extremely low computation cost, communication cost and fewer storage resources in smart card, medical servers and physical servers. What`s more, the PAKA protocol is proved secure against known possible attacks by using Burrows-Abadi-Needham (BAN) logic. As a result, these features make PAKA protocol is very suitable for computation-limited mobile device.

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